RESUMEN
A rare case of recurrent cervical cancer presenting multiple metastases to the small intestine is reported. A 69-year-old Japanese woman with a past history of early-stage (Ia) cervical cancer 13 years previously suffered sudden onset of panperitonitis caused by perforation of the small intestine. In the perforated lesion, squamous cell carcinoma, which was histologically similar to that of the primary lesion, was observed, and was diagnosed as a late recurrence of the cervical cancer. Perforation of the small intestine caused by tumor metastasis, especially metastasis from cervical cancer, rerely occurs. Furthermore, recurrence of an early cervical cancer presenting 13 years after hysterectomy is extremely rare. The present case draws attention to the possibility of late recurrence of cervical cancer, even in cases treated at the early-stage.
Asunto(s)
Carcinoma de Células Escamosas/patología , Histerectomía , Perforación Intestinal/etiología , Neoplasias del Cuello Uterino/complicaciones , Anciano , Carcinoma de Células Escamosas/complicaciones , Carcinoma de Células Escamosas/diagnóstico , Femenino , Humanos , Perforación Intestinal/patología , Intestino Delgado/patología , Microscopía Electrónica , Metástasis de la Neoplasia/complicaciones , Estadificación de Neoplasias , Recurrencia , Factores de Tiempo , Neoplasias del Cuello Uterino/diagnóstico , Neoplasias del Cuello Uterino/patologíaRESUMEN
Acute renal failure proved fatal in a patient with metastatic breast adenocarcinoma, complicated by the hemolytic-uremic syndrome. Low-grade hemolysis probably was ongoing prior to a third course of chemotherapy that included mitomycin. Terminal renal failure was caused by glomerular infarction and tubular necrosis. Schiztocytes in the blood smear and casts in the urine sediment may be relative contraindications to prolongation of tumor-lysis therapy. Recent advances in "rescue therapy" for hemolytic-uremic syndromes justify dialysis at least on a temporary basis.
Asunto(s)
Lesión Renal Aguda/complicaciones , Adenocarcinoma/tratamiento farmacológico , Neoplasias de la Mama/tratamiento farmacológico , Síndrome Hemolítico-Urémico/complicaciones , Mitomicinas/uso terapéutico , Lesión Renal Aguda/patología , Adenocarcinoma/complicaciones , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Neoplasias de la Mama/complicaciones , Femenino , Síndrome Hemolítico-Urémico/terapia , Humanos , Mitomicina , Mitomicinas/efectos adversos , Metástasis de la Neoplasia/complicaciones , Metástasis de la Neoplasia/tratamiento farmacológicoAsunto(s)
Fracturas del Cuello Femoral/cirugía , Adulto , Placas Óseas , Niño , Femenino , Fracturas del Cuello Femoral/diagnóstico por imagen , Fijación Interna de Fracturas , Fracturas Espontáneas/etiología , Prótesis de Cadera , Humanos , Masculino , Metástasis de la Neoplasia/complicaciones , RadiografíaRESUMEN
Se informa una paciente con neoplasia no linfomatosa asociada a gammapatía monoclonal. Este hallazgo ha sido informado por diferentes autore, pero su implicación continúa sujeta a discrepancias. Se revisan los elementos diferenciales entre el mieloma múltiple y la aparición de inmunoglobulina monoclonal en pacientes con neoplasias no reticulares; se exponen los criterios sobre esta asociación (AU)
Asunto(s)
Adulto , Humanos , Femenino , Hipergammaglobulinemia/complicaciones , Metástasis de la Neoplasia/complicacionesRESUMEN
Se informa una paciente con neoplasia no linfomatosa asociada a gammapatía monoclonal. Este hallazgo ha sido informado por diferentes autore, pero su implicación continúa sujeta a discrepancias. Se revisan los elementos diferenciales entre el mieloma múltiple y la aparición de inmunoglobulina monoclonal en pacientes con neoplasias no reticulares; se exponen los criterios sobre esta asociación
Asunto(s)
Adulto , Humanos , Femenino , Hipergammaglobulinemia/complicaciones , Metástasis de la Neoplasia/complicacionesRESUMEN
A case of hip osteoarthritis is reported, in which histological investigation demonstrated the absence of tumoral involvement in femoral head in spite of nearby intraosseous carcinomatous metastasis. It comes in addition to a previously reported similar personal case. Further studies of surgical or post-mortem specimens are needed to indicate whether these observations were fortuitous or whether the two conditions might not even be mutually exclusive.
Asunto(s)
Cabeza Femoral , Cuello Femoral , Metástasis de la Neoplasia/patología , Osteoartritis/patología , Anciano , Femenino , Humanos , Masculino , Metástasis de la Neoplasia/complicaciones , Osteoartritis/complicacionesAsunto(s)
Taponamiento Cardíaco/diagnóstico , Metástasis de la Neoplasia/diagnóstico , Anciano , Carcinoma de Células Escamosas , Taponamiento Cardíaco/etiología , Taponamiento Cardíaco/cirugía , Humanos , Neoplasias Pulmonares , Masculino , Invasividad Neoplásica , Metástasis de la Neoplasia/complicaciones , Metástasis de la Neoplasia/cirugía , Pericardio/cirugíaAsunto(s)
Fracturas Espontáneas/cirugía , Placas Óseas , Fracturas del Fémur/etiología , Displasia Fibrosa Ósea/complicaciones , Fijación Interna de Fracturas , Fijación Intramedular de Fracturas , Fracturas Espontáneas/etiología , Humanos , Metástasis de la Neoplasia/complicaciones , Osteogénesis Imperfecta/complicaciones , Diseño de Prótesis , Traumatismos Vertebrales/etiologíaRESUMEN
Pituitary ablation by the injection of alcohol through a transphenoidal needle has been practised for a number of years. In order to reduce the complications resulting from the spread of alcohol to neighbouring structures, a cryoprobe has been constructed which can be passed up through the needle into the gland and a series of localised lesions produced. The degree of pain relief is as good if not better than that obtained with alcohol. Only one instance of temporary blurring of vision resulted and hormonal disturbances were not seen. No difference was observed between the results obtained from the treatment of hormone-dependent and hormone-insensitive tumours. Pain caused in one patient by a benign tumour was unsuccessfully treated.
Asunto(s)
Criocirugía , Hipofisectomía/métodos , Metástasis de la Neoplasia/complicaciones , Dolor Intratable/cirugía , Criocirugía/efectos adversos , Femenino , Estudios de Seguimiento , Humanos , Hipofisectomía/efectos adversos , Masculino , Dolor Intratable/etiologíaRESUMEN
Data from 133 patients with cancer and suspected compression of the spinal cord or cauda equina was reviewed. Although there were differences in presenting symptoms and signs between the group of 62 patients with compression and the 71 without, no single symptom or sign discriminated adequately between the two groups. Multiple logistic regression was used to try to develop an index of signs and symptoms which could identify those without compression, thereby sparing them a myelogram. Eight characteristics, in combination, proved most effective as an index, but they were not perfect predictors of patients with block. Final diagnoses in the group without compression were: vertebral metastases 35%, carcinomatous meningitis 24%, plexopathy and/or neuropathy 21%, other 30% (10% had two diagnoses). Sixty-six percent of those with compression and 50% of those without compression died within six months, although patients rarely survived for much longer.
Asunto(s)
Cauda Equina/diagnóstico por imagen , Metástasis de la Neoplasia/complicaciones , Síndromes de Compresión Nerviosa/diagnóstico por imagen , Compresión de la Médula Espinal/diagnóstico por imagen , Adolescente , Adulto , Anciano , Niño , Femenino , Humanos , Masculino , Persona de Mediana Edad , Mielografía , Síndromes de Compresión Nerviosa/etiología , Pronóstico , Compresión de la Médula Espinal/etiologíaAsunto(s)
Infecciones por Clostridium/diagnóstico , Clostridium perfringens/aislamiento & purificación , Sepsis/diagnóstico , Adulto , Anciano , Enfermedades de las Vías Biliares/complicaciones , Enfermedades de las Vías Biliares/microbiología , Infecciones por Clostridium/complicaciones , Infecciones por Clostridium/mortalidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Metástasis de la Neoplasia/complicaciones , Metástasis de la Neoplasia/microbiología , Neoplasias/complicaciones , Neoplasias/microbiología , Neumonía/complicaciones , Neumonía/microbiología , Sepsis/complicaciones , Sepsis/mortalidad , Infecciones Urinarias/complicaciones , Infecciones Urinarias/microbiologíaRESUMEN
Factor VIII procoagulant activity, antigen concentration and von Willebrand activity as ristocetin cofactor were determined several times in 10 patients with DIC. These is a significant negative correlation between the DIC-score and the VIII:C/von Willebrand activity ratio.
Asunto(s)
Factores de Coagulación Sanguínea/análisis , Coagulación Intravascular Diseminada/sangre , Factor VIII/análisis , Factor de von Willebrand/análisis , Coagulación Intravascular Diseminada/etiología , Factor VIII/fisiología , Humanos , Cirrosis Hepática/complicaciones , Metástasis de la Neoplasia/complicaciones , Sepsis/complicaciones , Choque/complicacionesRESUMEN
29 out of 34 consecutive patients of pediatric age, operated upon for posterior fossa medulloblastoma, were divided into 2 groups according to the chemotherapeutic treatment (intrathecal methotrexate or intravenous cyclophosphamide) received at random after surgery and radiation treatment. The modalities of irradiation and chemotherapy are described. 9 patients have not yet shown a local recurrence and are alive at varous intervals after surgery. Only 1 patient with local recurrence is still alive 31 months after the primary operation. The mean actuarial survival of the whole series of patients is about 38 months. Differences between the two groups, concerning either the survival rate till local recurrence, or the general and neurologic conditions of survival, are not statistically significant. Hematologic toxicity was more pronounced in the group treated with cyclophosphamide, whereas late neurologic sequelae were a more prominent feature of the intrathecal methotrexate trial.