RESUMEN
The oral mucosa may be the site of lesions attributable to contact allergy with dental material. Studies carried out show that in oral LP dental materials may represent a factor of by no means negligible importance in determining the lesion as they might be the triggering cause and subsequently influence course and development. On the basis of these observations, an interpretative model of the aetiopathogenetic relationship between dental materials and oral LP is proposed and the problem is also addressed from the clinical viewpoint. The essential aspects are outlined and a diagnostic-therapeutic protocol proposed that differentiates patients suffering from oral LP with presence of dental materials and those without.
Asunto(s)
Materiales Dentales/efectos adversos , Hipersensibilidad/etiología , Liquen Plano/etiología , Enfermedades de la Boca/etiología , Corrosión , Materiales Dentales/inmunología , Dentaduras/efectos adversos , Humanos , Hipersensibilidad/diagnóstico , Pruebas del ParcheRESUMEN
In addition to toxic reactions to dental materials, some individuals may develop or exhibit hypersensitivity reactions to leachable components. An experimental model combining the guinea pig maximization test for induction of hypersensitivity and the subcutaneous implantation of dental cements is described. Guinea pigs immunized with AH 26, an epoxy-bisphenol resin, showed an increased tissue response to AH26 implants. Guinea pigs immunized with zinc oxide-eugenol did not show a similarly increased response, possibly because of an anti-inflammatory effect of eugenol. The experimental model may prove useful in predicting the effect of leachable allergens from dental materials in sensitized individuals.