Asunto(s)
Candida albicans/aislamiento & purificación , Candidiasis Bucal , Fluconazol/administración & dosificación , Lengua Vellosa , Administración Tópica , Anciano de 80 o más Años , Antifúngicos/administración & dosificación , Candidiasis Bucal/complicaciones , Candidiasis Bucal/diagnóstico , Candidiasis Bucal/tratamiento farmacológico , Candidiasis Bucal/fisiopatología , Femenino , Humanos , Lengua Vellosa/diagnóstico , Lengua Vellosa/tratamiento farmacológico , Lengua Vellosa/etiología , Lengua Vellosa/fisiopatología , Resultado del TratamientoRESUMEN
Black hairy tongue (BHT) is a benign medical condition characterized by elongated filiform lingual papillae with typical carpet-like appearance of the dorsum of the tongue. Its prevalence varies geographically, typically ranging from 0.6% to 11.3%. Known predisposing factors include smoking, excessive coffee/black tea consumption, poor oral hygiene, trigeminal neuralgia, general debilitation, xerostomia, and medication use. Clinical presentation varies but is typically asymptomatic, although aesthetic concerns are common. Differential diagnosis includes pseudo-BHT, acanthosis nigricans, oral hairy leukoplakia, pigmented fungiform papillae of the tongue, and congenital melanocytic/melanotic nevi/macules. Clinical diagnosis relies on visual observation, detailed history taking, and occasionally microscopic evaluation. Treatment involves identification and discontinuation of the offending agent, modifications of chronic predisposing factors, patient's re-assurance to the benign nature of the condition, and maintenance of adequate oral hygiene with gentle debridement to promote desquamation. Complications of BHT (burning mouth syndrome, halitosis, nausea, gagging, dysgeusia) typically respond to therapy. Prognosis is excellent with treatment of underlying medical conditions. BHT remains an important medical condition which may result in additional burden on the patient and health care system and requires appropriate prevention, recognition and treatment.
Asunto(s)
Lengua , Diagnóstico Diferencial , Humanos , Valor Predictivo de las Pruebas , Factores de Riesgo , Lengua/patología , Lengua/fisiopatología , Lengua Vellosa/diagnóstico , Lengua Vellosa/epidemiología , Lengua Vellosa/fisiopatología , Lengua Vellosa/terapia , Resultado del TratamientoAsunto(s)
Glositis Migratoria Benigna/diagnóstico , Anomalías de la Boca/diagnóstico , Higiene Bucal/métodos , Neoplasias de la Lengua/diagnóstico , Lengua Vellosa , Anciano , Anquiloglosia , Café/efectos adversos , Diagnóstico Diferencial , Humanos , Leucoplasia Vellosa/diagnóstico , Masculino , Melanoma/diagnóstico , Melanoma/patología , Factores de Riesgo , Fumar/efectos adversos , Lengua/patología , Neoplasias de la Lengua/patología , Lengua Vellosa/diagnóstico , Lengua Vellosa/etiología , Lengua Vellosa/fisiopatologíaRESUMEN
OBJECTIVE: The association between OSAS and patient history and physical exam findings is previously established; however, to our knowledge there are no studies that evaluate the role of tongue scalloping as a reliable clinical indicator for OSA, snoring, or the presence of other sleep pathology as evidenced by polysomnography. This study evaluates the hypothesis that such an association exists. SUBJECTS AND METHODS: Sixty-one otolaryngology clinic patients were evaluated by history and physical exam for the presence and degree of tongue scalloping, snoring, and other previously established clinical indicators for sleep-disordered breathing and obstructive apnea. Twenty-five of the 61 study patients were additionally evaluated by overnight polysomnography to provide conclusive diagnosis of sleep pathology. The degree of tongue scalloping was graded from 0 to 3 and its significance as a screening, diagnostic, and predictive factor for sleep pathology was then statistically determined. RESULTS: Twenty-seven patients (44%) had known or newly documented OSA and 47 (77%) had a history of snoring. Twenty-seven patients (44%) had some degree of tongue scalloping (1-3) and 74% of these patients were male. The presence of any degree of tongue scalloping (grade 1-3) in patients with known or newly documented OSA showed sensitivity, specificity, PPV, and NPV of 52%, 68%, 70%, and 50% respectively. The presence of tongue scalloping in patients with either known snoring history or newly documented snoring showed sensitivity, specificity, PPV, and NPV of 47%, 64%, 81%, and 26% respectively. Presence of tongue scalloping was 71% specific for abnormal sleep efficiency (<85%), 70% specific for abnormal AHI (>5), and 86% specific for nocturnal desaturation >4% below baseline. Presence of tongue scalloping also showed PPV of 67% for abnormal AHI, 89% for apnea or hypopnea, and 89% for nocturnal desaturation. Presence and severity of tongue scalloping showed positive correlation with increasing Mallampati and modified Mallampati airway classification. CONCLUSIONS: In high-risk patients we found tongue scalloping to be predictive of sleep pathology. Tongue scalloping was also associated with pathologic polysomnography data and abnormal Mallampati grades. We feel the finding of tongue scalloping is a useful clinical indicator of sleep pathology and that its presence should prompt the physician to inquire about snoring history.
Asunto(s)
Apnea Obstructiva del Sueño/etiología , Sueño/fisiología , Lengua Vellosa/complicaciones , Adulto , Anciano , Anciano de 80 o más Años , Progresión de la Enfermedad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Polisomnografía , Pronóstico , Factores de Riesgo , Índice de Severidad de la Enfermedad , Apnea Obstructiva del Sueño/diagnóstico , Apnea Obstructiva del Sueño/fisiopatología , Ronquido/complicaciones , Ronquido/diagnóstico , Ronquido/fisiopatología , Encuestas y Cuestionarios , Lengua Vellosa/diagnóstico , Lengua Vellosa/fisiopatologíaRESUMEN
Oral hairy leukoplakia was initially reported only in HIV-infected patients and was considered pathognomonic for HIV infection. The presence of Epstein-Barr virus and the decrease in Langerhans cells seem to be necessary for the development of oral hairy leukoplakia. HIV antigen is not present in oral hairy leukoplakia. We report on seven renal transplant recipients with oral hairy leukoplakia. In six of these patients no HIV infection was present. All patients showed marked immunosuppression following a vigorous immunosuppressive regimen. Five patients each had several rejection episodes, which were treated with further immunosuppressive therapy in addition to the basic immunosuppressive regimen. One patient was infected with HIV from the renal graft and another suffered from liver cirrhosis with portal hypertension caused by chronic hepatitis B infection. We believe that oral hairy leukoplakia is a marker for severe immunosuppression that is not necessarily associated with HIV infection. Organ transplant recipients undergoing dermatological check-up should be examined for oral hairy leukoplakia.
Asunto(s)
Tolerancia Inmunológica/fisiología , Trasplante de Riñón/inmunología , Leucoplasia Bucal/fisiopatología , Adulto , Femenino , Seropositividad para VIH/inmunología , Humanos , Técnicas Inmunológicas , Inmunosupresores/efectos adversos , Masculino , Persona de Mediana Edad , Lengua Vellosa/fisiopatologíaRESUMEN
Salivary condition and its correlation to tongue morphology was studied in 149 dental students. The students were divided according to the morphologic form of the tongue. The salivary pH and the buffer capacity of resting and stimulated saliva were determined. The pH values in the resting saliva of the fissured tongue group were more alkaline than those in the control group. The difference in pH values of stimulated saliva in the fissured tongue and control groups was only indicative. The stimulated saliva values of the normal tongue and the geographic tongue groups were similar. The pH valves of resting saliva in the geographic tongue group were more acidic than those in the normal tongue group. The salivary pH values of the filiform atrophy group were more acidic than those of the control group: resting salivar highly significantly and stimulated saliva significantly. The pH values of the hairy tongue group were also more acidic than those of the control group: both resting saliva and stimulated saliva highly significantly. No differences were observed in salivary buffer capacity, although buffer capacity in the hairy tongue group seemed to be lower than in the other groups.