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5.
Int Anesthesiol Clin ; 62(4): 48-58, 2024 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-39233571

RESUMEN

Tracheal intubation is a fundamental facet of airway management, for which the importance of achieving success at the first attempt is well recognized. Failure to do so can lead to significant morbidity and mortality if there is inadequate patient oxygenation by alternate means. The evidence supporting the benefits of a videolaryngoscope in attaining this objective is now overwhelming (in adults). This has led to its increasing recognition in international airway management guidelines and its promotion from an occasional airway rescue tool to the first-choice device during routine airway management. However, usage in clinical practice does not currently reflect the increased worldwide availability that followed the upsurge in videolaryngoscope purchasing during the coronavirus disease 2019 pandemic. There are a number of obstacles to widespread adoption, including lack of adequate training, fears over de-skilling at direct laryngoscopy, equipment and cleaning costs, and concerns over the environmental impact, among others. It is now clear that in order for patients to benefit maximally from the technology and for airway managers to fully appreciate its role in everyday practice, proper training and education are necessary. Recent research evidence has addressed some existing barriers to default usage, and the emergence of techniques such as awake videolaryngoscopy and video-assisted flexible (bronchoscopic) intubation has also increased the scope of clinical application. Future studies will likely further confirm the superiority of videolaryngoscopy over direct laryngoscopy, therefore, it is incumbent upon all airway managers (and their teams) to gain expertise in videolaryngoscopy and to use it routinely in their everyday practice..


Asunto(s)
Manejo de la Vía Aérea , Intubación Intratraqueal , Laringoscopía , Humanos , Laringoscopía/métodos , Manejo de la Vía Aérea/métodos , Intubación Intratraqueal/métodos , COVID-19 , Laringoscopios , Grabación en Video
6.
Int Anesthesiol Clin ; 62(4): 37-47, 2024 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-39233570

RESUMEN

ABSTRACT: Advanced airway management is a skill that is used every day in patient care settings throughout the world. Albeit common, it is not benign. Advanced airway management may either be elective or urgent; in either case, it may result in significant patient morbiidity and mortality. The complications of difficult or failed endotracheal intubation can be severe and include death or permanent neurologic injury. Difficulty or failure with advanced airway management often coincides with the onset of hypoxia. The onset of hypoxia affects both the patient and the airway manager. While hypoxemia may result in dysrhythmias and ultimately cardiac arrest for the patient, it adds time pressure and stress to the airway manager, and thus may impact successful performance. In this review, we will discuss how to identify patients at risk for rapid desaturation during advanced airway management. Additionally, methods of peri-oxygenation throughout the performance of airway management will be discussed.


Asunto(s)
Manejo de la Vía Aérea , Hipoxia , Intubación Intratraqueal , Humanos , Manejo de la Vía Aérea/métodos , Hipoxia/terapia , Intubación Intratraqueal/métodos , Terapia por Inhalación de Oxígeno/métodos , Oxígeno/administración & dosificación
7.
Int Anesthesiol Clin ; 62(4): 91-100, 2024 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-39233575

RESUMEN

ABSTRACT: Supraglottic airways have been utilized as an alternative to facemask ventilation and endotracheal intubation and thus have been essential to airway management since their introduction in the late 1980s. This chapter describes basic considerations in their use and an update on current clinical practice, with an emphasis on safe management. The devices have evolved to meet today's clinical airway challenges, and they provide benefits for patients and practitioners.


Asunto(s)
Manejo de la Vía Aérea , Intubación Intratraqueal , Máscaras Laríngeas , Humanos , Manejo de la Vía Aérea/métodos , Manejo de la Vía Aérea/instrumentación , Intubación Intratraqueal/métodos , Intubación Intratraqueal/instrumentación
8.
Int Anesthesiol Clin ; 62(4): 59-71, 2024 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-39233572

RESUMEN

Awake tracheal intubation (ATI) remains the "gold standard" technique in securing a definitive airway in conscious, self-ventilating patients with predicted or known difficult airways and the procedure is associated with a low failure rate. Since its inception a variety of techniques to achieve ATI have emerged and there have been accompanying advancements in pharmaceuticals and technology to support the procedure. In recent years there has been a growing focus on the planning, training and human factors involved in performing the procedure. The practice of ATI, does however, remain low around 1% to 2% of all intubations despite an increase in those with head and neck pathology. ATI, therefore, presents a skill that is key for the safety of patients but may not be practised with regularity by many anesthetists. In this article we therefore aim to highlight relevant guidance, recent literature and provide an update on the practical methods fundamental for successful ATI. We also discuss the crucial aspects of a safe airway culture and how this can help to embed training and maintenance of skills.


Asunto(s)
Intubación Intratraqueal , Vigilia , Humanos , Intubación Intratraqueal/métodos , Manejo de la Vía Aérea/métodos , Competencia Clínica
9.
Int Anesthesiol Clin ; 62(4): 101-114, 2024 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-39233576

RESUMEN

Emergency front-of-neck access refers to all techniques that deliver oxygen into the airway lumen through the anterior neck structures and encompasses access both through the cricothyroid membrane and the tracheal wall. There has yet to be a universal agreement regarding the preferred technique. A surgical incision is currently the most common approach in prehospital and in-hospital care. This review intends to review and summarize the existing clinical, basic science, and societal guidelines for eFONA.


Asunto(s)
Manejo de la Vía Aérea , Servicios Médicos de Urgencia , Cuello , Humanos , Cuello/cirugía , Manejo de la Vía Aérea/métodos , Servicios Médicos de Urgencia/métodos , Intubación Intratraqueal/métodos , Tráquea
10.
PLoS One ; 19(9): e0310146, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39241031

RESUMEN

Although prehospital emergency anesthesia (PHEA), with a specific focus on intubation attempts, is frequently studied in prehospital emergency care, there is a gap in the knowledge on aspects related to adherence to PHEA guidelines. This study investigates adherence to the "Guidelines for Prehospital Emergency Anesthesia in Adults" with regard to the induction of PHEA, including the decision making, rapid sequence induction, preoxygenation, standard monitoring, intubation attempts, adverse events, and administration of appropriate medications and their side effects. This retrospective study examined PHEA interventions from 01/01/2020 to 12/31/2021 in the city of Aachen, Germany. The inclusion criteria were adult patients who met the indication criteria for the PHEA. Data were obtained from emergency medical protocols. A total of 127 patients were included in this study. All the patients met the PHEA indication criteria. Despite having a valid indication, 29 patients did not receive the PHEA. 98 patients were endotracheally intubated. For these patients, monitoring had conformed to the guidelines. The medications were used according to the guidelines. A significant increase in oxygen saturation was reported after anesthesia induction (p < 0.001). The patients were successfully intubated endotracheally on the third attempt. Guideline adherence was maintained in terms of execution of PHEA, rapid sequence induction, preoxygenation, monitoring, selection, and administration of relevant medications. Emergency physicians demonstrated the capacity to effectively respond to cardiorespiratory events. Further investigations are needed on the group of patients who did not receive PHEA despite meeting the criteria. The underlying causes of decision making in these cases need to be evaluated in the future.


Asunto(s)
Anestesia , Servicios Médicos de Urgencia , Adhesión a Directriz , Humanos , Estudios Retrospectivos , Femenino , Masculino , Persona de Mediana Edad , Anciano , Anestesia/métodos , Adulto , Alemania , Intubación Intratraqueal , Anciano de 80 o más Años
11.
BMC Anesthesiol ; 24(1): 316, 2024 Sep 06.
Artículo en Inglés | MEDLINE | ID: mdl-39243003

RESUMEN

BACKGROUND: The primary objective of anesthesiologists during the induction of anaesthesia is to mitigate the operative stress response resulting from endotracheal intubation. In this prospective, randomized controlled trial, our aim was to assess the feasibility and efficacy of employing Index of Consciousness (IoC, IoC1 and IoC2) monitoring in predicting and mitigating circulatory stress induced by endotracheal intubation for laparoscopic cholecystectomy patients under general anesthesia (GA). METHODS: We enrolled one hundred and twenty patients scheduled for laparoscopic cholecystectomy under GA and randomly allocated them to two groups: IoC monitoring guidance (Group T, n = 60) and bispectral index (BIS) monitoring guidance (Group C, n = 60). The primary endpoints included the heart rate (HR) and mean arterial pressure (MAP) of the patients, as well as the rate of change (ROC) at specific time points during the endotracheal intubation period. Secondary outcomes encompassed the systemic vascular resistance index (SVRI), cardiac output index (CI), stroke volume index (SVI), ROC at specific time points, the incidence of adverse events (AEs), and the induction dosage of remifentanil and propofol during the endotracheal intubation period in both groups. RESULTS: The mean (SD) HR at 1 min after intubation under IoC monitoring guidance was significantly lower than that under BIS monitoring guidance (76 (16) beats/min vs. 82 (16) beats/min, P = 0.049, respectively). Similarly, the mean (SD) MAP at 1 min after intubation under IoC monitoring guidance was lower than that under BIS monitoring guidance (90 (20) mmHg vs. 98 (19) mmHg, P = 0.031, respectively). At each time point from 1 to 5 min after intubation, the number of cases with HR ROC of less than 10% in Group T was significantly higher than in Group C (P < 0.05). Furthermore, between 1 and 3 min and at 5 min post-intubation, the number of cases with HR ROC between 20 to 30% or 40% in Group T was significantly lower than that in Group C (P < 0.05). At 1 min post-intubation, the number of cases with MAP ROC of less than 10% in Group T was significantly higher than that in Group C (P < 0.05), and the number of cases with MAP ROC between 10 to 20% in Group T was significantly lower than that in Group C (P < 0.01). Patients in Group T exhibited superior hemodynamic stability during the peri-endotracheal intubation period compared to those in Group C. There were no significant differences in the frequencies of AEs between the two groups (P > 0.05). CONCLUSION: This promising monitoring technique has the potential to predict the circulatory stress response, thereby reducing the incidence of adverse reactions during the peri-endotracheal intubation period. This technology holds promise for optimizing anesthesia management. TRAIL REGISTRATION:  Chinese Clinical Trail Registry Identifier: ChiCTR2300070237 (20/04/2022).


Asunto(s)
Anestesia General , Monitores de Conciencia , Frecuencia Cardíaca , Intubación Intratraqueal , Monitoreo Intraoperatorio , Humanos , Anestesia General/métodos , Intubación Intratraqueal/métodos , Masculino , Femenino , Estudios Prospectivos , Persona de Mediana Edad , Adulto , Monitoreo Intraoperatorio/métodos , Frecuencia Cardíaca/fisiología , Colecistectomía Laparoscópica/métodos , Estado de Conciencia/efectos de los fármacos , Estrés Fisiológico , Presión Arterial , Propofol/administración & dosificación
12.
BMC Emerg Med ; 24(1): 157, 2024 Sep 02.
Artículo en Inglés | MEDLINE | ID: mdl-39218873

RESUMEN

BACKGROUND: Prehospital airway management remains crucial with regard to the quality and safety of emergency medical service (EMS) systems worldwide. In 2007, the benchmark study by Timmermann et al. hit the German EMS community hard by revealing a significant rate of undetected oesophageal intubations leading to an often-fatal outcome. Since then, much attention has been given to guideline development and training. This study evaluated the incidence and special circumstances of tube misplacement as an adverse peri-intubation event from a Helicopter Emergency Medical Services perspective. METHODS: This was a retrospective analysis of a German helicopter-based EMS database from January 1, 2012, to December 31, 2020. All registered patients were included in the primary analysis. The results were analysed using SPSS 27.0.1.0. RESULTS: Out of 227,459 emergency medical responses overall, a total of 18,087 (8.0%) involved invasive airway management. In 8141 (45.0%) of these patients, airway management devices were used by ground-based EMS staff, with an intubation rate of 96.6% (n = 7861), and alternative airways were used in 3.2% (n = 285). Overall, the rate of endotracheal intubation success was 94.7%, while adverse events in the form of tube misplacement were present in 5.3%, with a 1.2% rate of undetected oesophageal intubation. Overall tube misplacement and undetected oesophageal intubation occurred more often after intubation was carried out by paramedics (10.4% and 3.6%, respectively). In view of special circumstances, those errors occurred more often in the presence of trauma or cardiopulmonary resuscitation, with rates of 5.6% and 6.4%, respectively. Difficult airways with a Cormack 4 status were present in 2.1% (n = 213) of HEMS patients, accompanied by three or more intubation attempts in 5.2% (n = 11). CONCLUSIONS: Prehospital airway management success has improved significantly in recent years. However, adverse peri-intubation events such as undetected oesophageal intubation remain a persistent threat to patient safety. TRIAL REGISTRATION: The study was registered in the German Register for Clinical Studies (number DRKS00028068).


Asunto(s)
Ambulancias Aéreas , Manejo de la Vía Aérea , Servicios Médicos de Urgencia , Humanos , Estudios Retrospectivos , Alemania , Masculino , Femenino , Manejo de la Vía Aérea/métodos , Persona de Mediana Edad , Adulto , Anciano , Intubación Intratraqueal/efectos adversos , Intubación Intratraqueal/estadística & datos numéricos , Bases de Datos Factuales , Niño , Adolescente , Seguridad del Paciente
13.
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ; 36(7): 778-781, 2024 Jul.
Artículo en Chino | MEDLINE | ID: mdl-39223897

RESUMEN

Extracorporeal membrane oxygenation (ECMO) is commonly a transitional treatment way used in patients with severe heart and lung problem. Deoxidized blood is extracted through venous intubation, and then returned to the arterial or venous system after oxygenation. There is a risk of intubation-related infection in arterial or venous intubation. Once the infection occurs, it will prolong the patient's length of hospitalization stay, increase the mortality and medical expenses. Longer duration of ECMO and higher simplified acute physiology score (SAPS) were risk factors for infection. At present, the main diagnostic method for infection is blood culture. Ultrasound-guided percutaneous cannulation can reduce the occurrence of infection; if infection still occurs, antibiotics should be actively treated. In order to bring reference for clinical work, this article reviews the incidence, risk factors, diagnostic criteria, prevention strategies, treatment methods and other key points of ECMO intubation-related infection.


Asunto(s)
Oxigenación por Membrana Extracorpórea , Oxigenación por Membrana Extracorpórea/métodos , Humanos , Factores de Riesgo , Intubación Intratraqueal/métodos
14.
PLoS One ; 19(9): e0307723, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39283873

RESUMEN

In critically ill patients, endotracheal intubation (ETI) is lifesaving but carries a high risk of adverse events, notably hypoxemia. Preoxygenation is performed before introducing the tube to increase the safe apnea time. Oxygenation is monitored by pulse oximeter measurement of peripheral oxygen saturation (SpO2). However, SpO2 is unreliable at the high oxygenation levels produced by preoxygenation and, in the event of desaturation, may not decrease sufficiently early to allow preventive measures. The oxygen reserve index (ORI) is a dimensionless parameter that can also be measured continuously by a fingertip monitor and reflects oxygenation in the moderate hyperoxia range. The ORI ranges from 0 to 1 when arterial oxygen saturation (PaO2) varies between 100 to 200 mmHg, as occurs during preoxygenation. No trial has assessed the potential effects of ORI monitoring to guide preoxygenation for ETI in unstable patients. We designed a multicenter, two-arm, parallel-group, randomized, superiority, open trial in 950 critically ill adults requiring ETI. The intervention consists in monitoring ORI values and using an ORI target for preoxygenation of at least 0.6 for at least 1 minute. In the control group, preoxygenation is guided by SpO2 values recorded by a standard pulse oximeter, according to the standard of care, the goal being to obtain 100% SpO2 during preoxygenation, which lasts at least 3 minutes. The standard-of-care ETI technique is used in both arms. Baseline parameters, rapid-sequence induction medications, ETI devices, and physiological data are recorded. The primary outcome is the lowest SpO2 value from laryngoscopy to 2 minutes after successful ETI. Secondary outcomes include cognitive function on day 28. Assuming a 10% standard deviation for the lowest SpO2 value in the control group, no missing data, and crossover of 5% of patients, with the bilateral alpha risk set at 0.05, including 950 patients will provide 85% power for detecting a 2% between-group absolute difference in the lowest SpO2 value. Should ORI monitoring with a target of ≥0.6 be found to increase the lowest SpO2 value during ETI, then this trial may change current practice regarding preoxygenation for ETI. Trial registration: Registered on ClinicalTrials.gov (NCT05867875) on April 27, 2023.


Asunto(s)
Unidades de Cuidados Intensivos , Intubación Intratraqueal , Oximetría , Saturación de Oxígeno , Oxígeno , Humanos , Intubación Intratraqueal/métodos , Oximetría/métodos , Oxígeno/metabolismo , Monitoreo Fisiológico/métodos , Enfermedad Crítica , Masculino , Adulto , Femenino , Persona de Mediana Edad
18.
Minerva Anestesiol ; 90(9): 739-747, 2024 09.
Artículo en Inglés | MEDLINE | ID: mdl-39279480

RESUMEN

BACKGROUND: Endotracheal intubation is a frequently performed procedure in anesthesia practice, and ensuring the correct inflation of the cuff is essential for maintaining the airway seal. Overinflation of endotracheal tube (ETT) cuffs can lead to complications, such as postoperative sore throat. This study aimed to compare the incidence of elevated ETT cuff pressure between saline and air inflation in elective laparoscopic abdominal surgery. METHODS: The study involved 60 participants ranging in age from 18 to 65, with American Society of Anesthesiologists physical status levels 1-2, who underwent laparoscopic abdominal surgery. We randomly assigned patients to two groups: Group A (air-filled ETT cuffs, N.=30) and Group S (saline-filled ETT cuffs, N.=30). Intra-cuff pressure was recorded before and after CO2 insufflation, as well as during changes in patient position. The number of interventions to restore intra-cuff pressure to 18 mmHg was documented. Peak airway pressure, plateau pressure, and positive end-expiratory pressure (PEEP) were measured at 15-minute intervals. RESULTS: The number of interventions needed to maintain intra-cuff pressure was significantly lower in the saline group compared to the air group. All patients started with initial cuff pressures above 20 mmHg. After insufflation, the first-minute cuff pressures were higher in the air group (P=0.001). Both groups experienced a significant increase in intra-cuff pressure with the Trendelenburg position, and after moving to the reverse Trendelenburg position (saline and air groups, P=0.001 and 0.012, respectively), the air group had higher intra-cuff pressure than the saline group (P=0.002). There were no significant differences between groups in peak airway pressure, plateau pressure, and PEEP. CONCLUSIONS: Inflating ETT cuffs with saline instead of air during laparoscopic abdominal surgeries led to a reduced requirement for interventions in maintaining pressure. This indicates that the use of saline inflation may significantly lower the risk of high cuff pressure and related complications.


Asunto(s)
Abdomen , Intubación Intratraqueal , Laparoscopía , Solución Salina , Humanos , Intubación Intratraqueal/métodos , Masculino , Persona de Mediana Edad , Femenino , Adulto , Abdomen/cirugía , Anciano , Solución Salina/administración & dosificación , Aire , Adulto Joven , Presión , Adolescente
19.
BMJ Case Rep ; 17(9)2024 Sep 13.
Artículo en Inglés | MEDLINE | ID: mdl-39277193

RESUMEN

Blunt injury to the neck following high-impact trauma can be associated with airway injury. The anaesthesiologist should have a high index of suspicion for the same when the patient presents for any surgical intervention for trauma. A complete evaluation of the tracheobronchial tree using a flexible bronchoscope is essential before instrumenting the airway in a child with suspected laryngotracheal trauma because blind intubation can convert a lesser grade airway trauma into a significant one. We report the airway management in a child belonging to middle childhood, who presented with complete tracheal transection after a blunt laryngotracheal trauma.


Asunto(s)
Manejo de la Vía Aérea , Broncoscopía , Laringe , Tráquea , Heridas no Penetrantes , Humanos , Heridas no Penetrantes/complicaciones , Heridas no Penetrantes/cirugía , Tráquea/lesiones , Tráquea/cirugía , Laringe/lesiones , Laringe/cirugía , Manejo de la Vía Aérea/métodos , Masculino , Niño , Intubación Intratraqueal/métodos , Traumatismos del Cuello/cirugía , Traumatismos del Cuello/complicaciones
20.
Acta Cir Bras ; 39: e395724, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39258618

RESUMEN

PURPOSE: Shock, cardiovascular problems, and respiratory failure constitute the main causes of death in patients cared in medical emergency rooms. Patients commonly require orotracheal intubation (OTI), a fact that has been intensified by diseases that generate important and fatal hemodynamic and respiratory problems in the affected patient. METHODS: Although etomidate (ETO) is a highly used anesthetic for OTI, its use remains controversial in several scenarios. Some studies refer to an increase in mortality with its use in critically patients, while others do not refer to a difference. Therefore, we evaluated the mortality of patients submitted to OTI in the public hospital of a public federal university, with the use of ETO and other sedative-hypnotic drugs used in the induction of the performance of OTI, with the in-hospital mortality of patients cared in hospital. RESULTS: The results demonstrate that the use of ETO as a hypnotic for OTI in the emergency room is not associated with a significant difference in morbidity or early mortality, within 30 days of hospitalization, compared with other hypnotics. CONCLUSIONS: There was no difference in mortality between patients intubated in the emergency department who used ETO and those who used non-ETO hypnotic within 72 hours and 30 days.


Asunto(s)
COVID-19 , Servicio de Urgencia en Hospital , Etomidato , Mortalidad Hospitalaria , Hipnóticos y Sedantes , Intubación Intratraqueal , Humanos , Intubación Intratraqueal/métodos , Servicio de Urgencia en Hospital/estadística & datos numéricos , Masculino , Femenino , Persona de Mediana Edad , Hipnóticos y Sedantes/administración & dosificación , Hipnóticos y Sedantes/uso terapéutico , Anciano , Adulto , Pandemias , SARS-CoV-2 , Brasil/epidemiología , Anestésicos Intravenosos/administración & dosificación
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