RESUMEN
We describe here a disease related to mite-associated ulcerative dermatitis in BALB/c mice, a strain previously classified as resistant to this condition. The disease was recognized by pruritic cutaneous pathology and wasting. Pathologic studies showed a marked allergic-type inflammation in the skin. The dominant histologic feature was extensive mast cell infiltration in cutaneous lesions and in lymphoid tissues, associated with a greatly elevated serum IgE concentration. The disease was secondary to infestation with an acarian ectoparasite Myocoptes musculinus, and seemed to represent an allergic reaction to the parasite-derived substances, with an associated wasting syndrome. This condition may be a useful experimental model for allergic diseases.
Asunto(s)
Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Alérgica por Contacto/inmunología , Infestaciones por Ácaros/inmunología , Trastornos Nutricionales/diagnóstico , Animales , Dermatitis Alérgica por Contacto/orina , Femenino , Inmunoglobulina A/análisis , Inmunoglobulina A/sangre , Inmunoglobulina E/análisis , Inmunoglobulina E/sangre , Inmunoglobulina G/análisis , Inmunoglobulina G/sangre , Ganglios Linfáticos/anatomía & histología , Masculino , Ratones , Ratones Endogámicos BALB C , Infestaciones por Ácaros/terapia , Infestaciones por Ácaros/orina , Trastornos Nutricionales/orina , Piel/anatomía & histologíaRESUMEN
Nine Hereford calves were infested with Psoroptes ovis and were allowed to develop clinical mange during a 9-week period. Blood, serum, and urine samples were obtained before and after calves were infested and were compared with those from 3 noninfested control calves. All calves were euthanatized and necropsied 9 weeks after they were infested. Gross and microscopic anatomic changes occurred only in the skin. Calves developed typical exudative dermatitis, the extent of which was dependent on population density of mites. Severely infested calves (50% to 70% of skin with dermatitis) developed a mild anemia and lymphopenia with marked neutropenia and variable eosinophilia. There were also increases in fibrinogen, gamma-globulin, and in vitro lymphocyte response to mitogen stimulation and decreases in anion gap cortisol, albumin, albumin/globulin ratio, and fractional Na clearance values. The severity of many of the changes could be correlated with the extent of dermatitis.
Asunto(s)
Enfermedades de los Bovinos/parasitología , Infestaciones por Ácaros/veterinaria , Animales , Análisis Químico de la Sangre/veterinaria , Bovinos , Enfermedades de los Bovinos/sangre , Enfermedades de los Bovinos/orina , Femenino , Linfocitos/fisiología , Infestaciones por Ácaros/sangre , Infestaciones por Ácaros/orinaRESUMEN
In the urine of a ten-year-old girl mites of the species Tarsonemus minusculus (Can et Fanz.) and Cheyletus eruditus (Schr.) were found. A following examination of the bed dust from the bed of the child produced yet two further species of house dust mites Dermatophagoides pteronyssinus (Trouess) and Tyrophagus putrescentiae (Schr.). The demonstration of Tarsonemus minusculus in this area is new, just as the hitherto unknown male of this species.
Asunto(s)
Ropa de Cama y Ropa Blanca , Polvo , Infestaciones por Ácaros , Ácaros , Animales , Lechos , Niño , Femenino , Humanos , Masculino , Infestaciones por Ácaros/orina , Sistema Urogenital/parasitologíaRESUMEN
The present paper reports on 7 cases of primary infections, pyelonephritis and pyelocystitis, in which acrids were found in the urine during acute attacks. The cases were detected in the clinical laboratory of a county Hospital. All the 7 patients, ranging in age from 6 to 60 years, exhibited characteristic symptoms of pyelonephritis and pyelocystitis. Numerous acarids were found in the urinary sediment and, in some cases, also their eggs. Some of the acarids were motile, others were encrusted with salts. A female acarid was detected while laying eggs. In 6 patients the acardis were found in the urine only at the first examination and disappeared following the of urinary infection; in the seventh case they were detected at three consecutive examinations performed at 3--6 days interval.