RESUMEN

A retrospective analysis of 21 hirsute women seen at a gynaecological endocrine clinic revealed a high incidence of infertility, menstrual irregularities and abnormal androgen profile. Polycystic ovarian syndrome (PCOS) was the underlying abnormality in the majority of cases. Cyproterone acetate (CPA) with ethinyl oestradiol in a reverse sequential regime was more effective and better tolerated but much more expensive than the combination of spironolactone and the oral contraceptive pill (OCP).

Asunto(s)

Antagonistas de Andrógenos/uso terapéutico , Ciproterona/análogos & derivados , Etinilestradiol/uso terapéutico , Hirsutismo/tratamiento farmacológico , Espironolactona/uso terapéutico , Adolescente , Adulto , Ciproterona/uso terapéutico , Acetato de Ciproterona , Quimioterapia Combinada , Femenino , Hirsutismo/economía , Humanos , Estudios Retrospectivos , Trinidad y Tobago