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1.
Int Urogynecol J ; 30(10): 1673-1677, 2019 10.
Artículo en Inglés | MEDLINE | ID: mdl-30643976

RESUMEN

INTRODUCTION AND HYPOTHESIS: This study aimed to determine whether incontinence to flatus is associated with women's bother in a symptomatic population and with sonographically diagnosed external anal sphincter (EAS) trauma. METHODS: This is a retrospective study of women attending a tertiary urogynecological unit between May 2013 and November 2015. Baseline evaluation included a standardized interview with St. Mark's Incontinence Score (SMIS) and visual analog scale (VAS) assessment for bother, as well as a physical examination and translabial pelvic floor ultrasound. At least one volume obtained covered the entire length of the EAS. These volumes were analyzed with the reviewer blinded to all clinical data. RESULTS: During the inclusion period, 1104 patients visited the unit. Fifty-three patients were excluded from the study for missing data, leaving 1051 for final analysis. Mean age was 57 years (56-58) and mean body mass index (BMI) 29.1 kg/m2 (28.8-29.6). The prevalence of any anal incontinence (AI) and flatus incontinence were 16.4% (172/1051) and 13.9% (146/1051), respectively. In the group of patients with AI, mean SMIS was 11.8 (11.0-12.6), and mean VAS for AI bother was 5.4 (5.0-5.9). Significant EAS trauma was detected in 9.8% (103/1051) of patients and was associated with flatus incontinence (p = 0.002). Including a flatus incontinence question in the SMIS questionnaire improved the prediction of patient bother from AI (R2 87.8% versus R2 86.3%, p = 0.04). CONCLUSIONS: Flatus incontinence is associated with ultrasound findings of EAS trauma and with higher patient bother from AI.


Asunto(s)
Canal Anal/diagnóstico por imagen , Incontinencia Fecal/psicología , Flatulencia/psicología , Canal Anal/lesiones , Incontinencia Fecal/diagnóstico por imagen , Femenino , Flatulencia/diagnóstico por imagen , Humanos , Persona de Mediana Edad , Estudios Retrospectivos , Ultrasonografía
2.
Liver Int ; 37(1): 141-147, 2017 01.
Artículo en Inglés | MEDLINE | ID: mdl-27375263

RESUMEN

BACKGROUND & AIMS: Excessive intestinal gas and liver steatosis are frequent sonographic findings. Both of these appear to be caused by variations of the gut microflora. We assessed the relationship between ultrasonographic detection of intestinal gas and liver steatosis. METHODS: This study included 204 consecutive patients (99 male; mean age 53.0 ± 15.6 years), who underwent ultrasonography for abdominal complaints or follow-up of benign lesions. Body mass index, biochemical liver markers, sonographic presence of liver steatosis and/or degree of intestinal gas interfering with the examination were collected. Both sonographic findings were assessed based on standardized criteria. The association between liver steatosis and intestinal gas was evaluated by means of univariate and multivariate analyses. RESULTS: Eighty (39.2%) of patients showed moderate to large amounts of gas preventing an accurate evaluation of the liver or pancreas and 90 (44.1%) had liver steatosis. A significant correlation between the degree of intestinal gas and liver steatosis both in obese (r=.603; P<.001) and in nonobese patients (r=.555; P<.001) was found. Univariate analysis showed that intestinal gas, body mass index, aspartate transaminase, alanine transaminase, gamma-GT, age and sex were predictors of liver steatosis; only intestinal gas (OR 7.4; 95% CI 3.4-16.1) and body mass index (OR; 1.4, 95% CI 1.2-1.5), however, were independent predictors at multivariate analysis. The presence of excessive gas was also significantly correlated with liver steatosis coupled with elevated ALT (P = .001). CONCLUSION: This study shows a significant correlation between excessive intestinal gas and liver steatosis. The reasons of this finding and its clinical implications remain to be defined.


Asunto(s)
Hígado Graso/fisiopatología , Flatulencia/fisiopatología , Hígado/fisiopatología , Obesidad/complicaciones , Adulto , Anciano , Índice de Masa Corporal , Hígado Graso/diagnóstico por imagen , Femenino , Flatulencia/diagnóstico por imagen , Motilidad Gastrointestinal , Humanos , Italia , Hígado/diagnóstico por imagen , Modelos Logísticos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Estudios Prospectivos , Índice de Severidad de la Enfermedad , Ultrasonografía , gamma-Glutamiltransferasa/metabolismo
3.
J Med Case Rep ; 8: 136, 2014 May 05.
Artículo en Inglés | MEDLINE | ID: mdl-24886457

RESUMEN

INTRODUCTION: Radiotherapy is a standard treatment for prostate cancer, and image-guided radiotherapy is increasingly being used to aid precision of dose delivery to targeted tissues. However, precision during radiotherapy cannot be maintained when unexpected intrafraction organ motion occurs. CASE PRESENTATION: We report our experience of internal organ motion caused by persistent gas production in a patient taking an alpha-glucosidase inhibitor. A 68-year-old Japanese man with prostate cancer visited our institution for treatment with helical tomotherapy. He suffered from diabetes mellitus and took an alpha-glucosidase inhibitor. Routine treatment planning computed tomography showed a large volume of rectal gas; an enema was given to void the rectum. Subsequent treatment planning computed tomography again showed a large volume of gas. After exercise (walking) to remove the intestinal gas, a third scan was performed as a test scan without tight fixation, which showed a sufficiently empty rectum for planning. However, after only a few minutes, treatment planning computed tomography again showed extreme accumulation of gas. Therefore, we postponed treatment planning computed tomography and consulted his doctor to suspend the alpha-glucosidase inhibitor, which was the expected cause of his persistent gas. Four days after the alpha-glucosidase inhibitor regimen was suspended, we took a fourth treatment planning computed tomography and made a treatment plan without gas accumulation. Thereafter, the absence of rectal gas accumulation was confirmed using daily megavolt computed tomography before treatment, and the patient received 37 fractions of intensity-modified radiotherapy at 74 Gy without rectal gas complications. In this case study, the alpha-glucosidase inhibitor induced the accumulation of intestinal gas, which may have caused unexpected organ motion, untoward reactions, and insufficient doses to clinical targets. CONCLUSIONS: We suggest that patients who are taking an alpha-glucosidase inhibitor for diabetes should discontinue use of that particular medicine prior to beginning radiotherapy.


Asunto(s)
Diabetes Mellitus Tipo 2/tratamiento farmacológico , Flatulencia/inducido químicamente , Inhibidores de Glicósido Hidrolasas/efectos adversos , Neoplasias de la Próstata/radioterapia , Planificación de la Radioterapia Asistida por Computador/métodos , Radioterapia de Intensidad Modulada/métodos , Anciano , Diabetes Mellitus Tipo 2/complicaciones , Flatulencia/diagnóstico por imagen , Humanos , Masculino , Neoplasias de la Próstata/complicaciones , Recto/diagnóstico por imagen , Tomografía Computarizada por Rayos X
4.
J Med Imaging Radiat Oncol ; 58(2): 253-6, 2014 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-24314069

RESUMEN

PURPOSE: This study aims to clarify the time-course of gas accumulation in the rectum during treatment as guidance for the management of rectal volumes. MATERIALS AND METHODS: We reviewed 2042 sets (35.2 sets per patient) of anteroposterior and right-left mega voltage (MV) images obtained for daily set-up from 58 patients who underwent radical external beam radiotherapy for localised prostate cancer. The patients were instructed to take magnesium oxide tablets during radiotherapy. They were also encouraged to avoid foods that might cause intestinal gas during radiotherapy. Gas accumulation in the rectum was graded into three classes by the same radiation oncologist. If no gas was seen in the rectum, it was classified as grade 0. A small amount of gas was classified as grade 1, whereas a marked amount of gas that required removal was classified as grade 2. RESULTS: Of the 2042 sets of MV images, grades 1 and 2 gas accumulation were seen in 332 (16%) and 156 (8%), respectively. By the trend test, gas accumulation significantly decreased towards the end of treatment (P = 0.02 for grade 1 or 2 and P = 0.02 for grade 2). On multivariate analysis, we did not identify any significant independent predictors for either baseline gas accumulation or gas reduction. CONCLUSION: Gas accumulation tended to decrease until the end of treatment. This tendency should be reconfirmed by other institutions.


Asunto(s)
Absorción de Radiación , Flatulencia/complicaciones , Neoplasias de la Próstata/complicaciones , Neoplasias de la Próstata/radioterapia , Dosificación Radioterapéutica , Radioterapia Conformacional/métodos , Recto/diagnóstico por imagen , Anciano , Anciano de 80 o más Años , Flatulencia/diagnóstico por imagen , Humanos , Masculino , Persona de Mediana Edad , Neoplasias de la Próstata/diagnóstico por imagen , Radiografía , Estudios Retrospectivos , Resultado del Tratamiento
5.
J Ark Med Soc ; 111(6): 110-1, 2014 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-25654924

RESUMEN

We present a case of a middle-aged patient presenting with acute onset abdominal pain and distension who had signs of bowel obstruction on physical exam. He was afebrile, hemodynamically stable with no peritoneal signs. Abdominal radiograph and CT scan were pathognomic for sigmoid volvulus. Through this case report we want to discuss the presentation, diagnosis, management options for sigmoid volvulus and importance of features suggestive of ischemic bowel that necessitates different management options.


Asunto(s)
Dolor Abdominal/diagnóstico por imagen , Colonoscopía/métodos , Flatulencia/diagnóstico por imagen , Vólvulo Intestinal/diagnóstico por imagen , Tomografía Computarizada por Rayos X/métodos , Dolor Abdominal/terapia , Enfermedad Aguda , Flatulencia/terapia , Humanos , Vólvulo Intestinal/terapia , Masculino , Persona de Mediana Edad
6.
Hepatobiliary Pancreat Dis Int ; 11(3): 314-8, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-22672827

RESUMEN

BACKGROUND: Disturbance of gastrointestinal function is a common complication in the early phase of acute pancreatitis (AP). Intestinal gas may reflect the function of the gut. Using plain abdominal radiographs, we investigated whether intestinal gas volume is related to AP. METHODS: Plain abdominal radiographs of 68 patients with AP within 24 hours after admission and 21 normal controls were digitized and transmitted to a computer. The region of intestinal gas was identified by an image manipulation software and the gas volume score (GVS) was calculated. The relationships between the GVS values and various clinical factors of AP were analyzed. RESULTS: The GVS in the AP group was 0.084+/-0.016, in the mild AP (MAP) group 0.070+/-0.005, and in the severe AP (SAP) group 0.094+/-0.013; all values were higher than that in the control group (P<0.01). The GVS in the SAP group was higher than that in the MAP group. The GVSs were correlated to the Ranson's scores (r=0.762, P<0.01) and the acute physiology and chronic health evaluation II (APACHE II) scores (r=0.801, P<0.01). In addition, the GVS in patients with secondary pancreatic and/or peripancreatic infection was 0.107+/-0.014, higher than that in patients without secondary infection (P<0.01). GVS was not related to gender, age, etiology or clinical outcome of AP. CONCLUSIONS: Intestinal gas volume is significantly elevated in patients with AP. It is closely related to Ranson's and APACHE II score and secondary pancreatic and/or peripancreatic infection. GVS may be a new prognostic tool for assessing the severity of AP in the early course of the disease.


Asunto(s)
Flatulencia/diagnóstico por imagen , Gases/metabolismo , Intestinos/diagnóstico por imagen , Pancreatitis/diagnóstico por imagen , APACHE , Enfermedad Aguda , Adolescente , Anciano , Análisis de Varianza , China , Femenino , Flatulencia/etiología , Flatulencia/metabolismo , Humanos , Mucosa Intestinal/metabolismo , Masculino , Pancreatitis/complicaciones , Valor Predictivo de las Pruebas , Pronóstico , Interpretación de Imagen Radiográfica Asistida por Computador , Radiografía Abdominal , Estudios Retrospectivos , Índice de Severidad de la Enfermedad
8.
AJR Am J Roentgenol ; 195(6): 1316-23, 2010 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-21098189

RESUMEN

OBJECTIVE: The purpose of this article is to compare the T-staging accuracy and lesion detectability of MDCT with gas distention versus water distention according to the surgical and histopathologic findings, for the preoperative evaluation of gastric cancer. MATERIALS AND METHODS: For a 3-month period, 113 consecutive patients (72 men and 41 women; age range, 23-85 years; mean age, 58 years) with 116 surgically confirmed gastric cancers from a single institution were included in our study. All patients had undergone preoperative MDCT with either effervescent granules taken orally (n = 55) or after having drunk 1,000 mL of tap water (n = 58) to create gastric distention. In addition to transverse images, multiplanar reformation images and 3D surface shaded display images were also obtained with gas distention CT, and multiplanar reformation images were obtained with water distention CT. The CT images were retrospectively reviewed by two abdominal radiologists separately with regard to T staging and lesion detectability. The accuracy values were compared between the two methods using Fisher's exact test. RESULTS: The T-staging accuracy for gastric cancer did not differ significantly between gas distention and water distention CT scans, according to both radiologists (p > 0.05). Furthermore, the staging accuracy values for T1a cancers on gas distention CT scans for radiologists 1 and 2 were also comparable with those of water distention CT scans (91.1% vs 85% for radiologist 1 and 89.3% vs 85% for radiologist 2; p > 0.05). However, the tumor detection rate was significantly higher on gas distention CT scans using 2D and surface shaded display images for both radiologists (94.6% for radiologist 1 and 91.1% for radiologist 2), compared with the rates for water distention CT scans (78.3% and 73.3%) or gas distention CT scans using only 2D images (75.0% and 67.9%) (p < 0.05). CONCLUSION: MDCT using the gas distention technique showed performance comparable to that of the water distention technique for the T staging of preoperative gastric cancer with better lesion detectability.


Asunto(s)
Imagenología Tridimensional , Neoplasias Gástricas/patología , Tomografía Computarizada por Rayos X/métodos , Adulto , Anciano , Anciano de 80 o más Años , Medios de Contraste , Femenino , Flatulencia/diagnóstico por imagen , Gases , Humanos , Yohexol/análogos & derivados , Masculino , Persona de Mediana Edad , Invasividad Neoplásica , Estadificación de Neoplasias , Estudios Retrospectivos , Neoplasias Gástricas/diagnóstico por imagen , Neoplasias Gástricas/cirugía , Agua
9.
Am J Gastroenterol ; 105(4): 876-82, 2010 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-20179685

RESUMEN

OBJECTIVES: We sought to evaluate colonic gas accommodation, ileocecal competence, and colonic clearance in subgroups patients with abdominal bloating. METHODS: Thirty-six patients complaining of abdominal bloating (12 constipation-predominant irritable bowel syndrome (IBS-C), 12 diarrhea-predominant irritable bowel syndrome (IBS-D), and 12 functional bloating) and 18 healthy controls were studied. Abdominal perception and girth were measured during: (i) 1 h continuous infusion of gas at 24 ml/min into the rectum (accommodation period) and (ii) 30 min free rectal gas evacuation (clearance period). In eight patients and eight healthy subjects, the gas infused was labeled with radioactive xenon (74 MBq (133)Xe), and gas distribution was determined by scintigraphy. RESULTS: Colonic gas accommodation produced significantly more abdominal symptoms and distension in patients than in healthy subjects (3.8+/-0.2 vs. 2.4+/-0.3 perception score; P<0.001; 10.9+/-0.6 vs. 8.3+/-0.5 mm girth increment; P=0.009). Scintigraphy showed no differences in colonic gas distribution and no ileal gas reflux, but patients exhibited impaired gas clearance from the proximal colon (63%+/-10% clearance in 30 min vs. 80%+/-2% in health; P=0.042), resulting in more residual gas (506+/-46 vs. 174+/-47 ml; P<0.001), perception (1.9+/-0.2 vs. 1.0+/-0.2 score; P=0.015), and girth increment (4.2+/-0.7 vs. 2.2+/-0.5 mm; P=0.024); IBS-C patients exhibited increased sensation and objective distension, as opposed to sensation only in IBS-D and distension only in functional bloating. CONCLUSIONS: Patients with abdominal bloating have normal colonic accommodation and ileocecal competence but impaired gas clearance from the proximal colon after retrograde infusion, and the consequences of this dysfunction are related to bowel habit.


Asunto(s)
Abdomen/fisiopatología , Colon/fisiopatología , Flatulencia/fisiopatología , Síndrome del Colon Irritable/fisiopatología , Abdomen/diagnóstico por imagen , Adolescente , Adulto , Anciano , Análisis de Varianza , Estudios de Casos y Controles , Distribución de Chi-Cuadrado , Colon/diagnóstico por imagen , Femenino , Flatulencia/diagnóstico por imagen , Tránsito Gastrointestinal , Humanos , Síndrome del Colon Irritable/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Percepción , Cintigrafía , Estadísticas no Paramétricas , Encuestas y Cuestionarios , Radioisótopos de Xenón
11.
Am J Gastroenterol ; 103(8): 2036-42, 2008 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-18802999

RESUMEN

BACKGROUND: It is unknown if abdominal bloating is attributable to excess abdominal gas or improved by a prokinetic agent. AIMS: To assess abdominal gas content in functional abdominal bloating and to ascertain the effect of a prokinetic agent on intestinal gas symptoms in these patients. METHODS: In 20 patients, intra-abdominal gas content and symptoms were quantified before and during treatment with pyridostigmine (30 mg/8 hp. o) in this randomized, placebo-controlled, double-blind study. Daily symptoms were quantified for 5 days before and 10 days during treatment, and abdominal gas volume was quantified by CT imaging before and at the fourth day of treatment. A CT scan was also obtained in 10 healthy subjects. RESULTS: Before treatment, the total volume of intestinal gas was similar in patients (112 +/- 18 mL) and in healthy controls (116 +/- 20 mL). The treatment-induced change in total and regional intestinal gas volume was not significantly different between pyridostigmine (-4 +/- 18 mL; mean +/- SEM) and placebo (0 +/- 15 mL). However, pyridostigmine reduced the severity of bloating from 3.3 +/- 0.3 to 2.6 +/- 0.4 (P < 0.05), whereas placebo did not (3.2 +/- 0.3 vs 3.0 +/- 0.4), although the change did not reach statistical difference across groups. CONCLUSION: In patients complaining of functional bloating, the volume and distribution of intestinal gas, measured on nonselected days, is comparable to asymptomatic subjects. Prokinetic stimulation improves bloating sensation without detectable changes in gas content.


Asunto(s)
Dolor Abdominal/tratamiento farmacológico , Inhibidores de la Colinesterasa/uso terapéutico , Flatulencia/tratamiento farmacológico , Síndrome del Colon Irritable/tratamiento farmacológico , Bromuro de Piridostigmina/uso terapéutico , Dolor Abdominal/diagnóstico por imagen , Dolor Abdominal/etiología , Adulto , Anciano , Método Doble Ciego , Femenino , Flatulencia/diagnóstico por imagen , Flatulencia/etiología , Motilidad Gastrointestinal , Humanos , Síndrome del Colon Irritable/complicaciones , Síndrome del Colon Irritable/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Proyectos Piloto , Radiografía
12.
Int J Radiat Oncol Biol Phys ; 72(2): 456-66, 2008 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-18374517

RESUMEN

PURPOSE: To evaluate the prostate and seminal vesicle motion in patients during both simulation and radiotherapy by rectal gas removal. METHODS AND MATERIALS: A total of 34 patients were treated in a whole pelvic radiotherapy (WPRT) arm and 42 patients in a non-WPRT arm. Of the 76 patients, 42 (26 in the non-WPRT arm and 16 in the WPRT arm) were instructed to insert their index finger and wash their rectums to evacuate their rectal gas. In addition to the planning computed tomography scan, three subsequent computed tomography scans were obtained during RT. The organs were outlined on each computed tomography image. Changes in the position of the prostate and seminal vesicles were analyzed using the center of mass (COM) coordinate system. The time trend, overall variations, systematic variations, and random variations were analyzed. RESULTS: The average cross-sectional area in the rectal gas removal group was significantly smaller than in all patients and in the WPRT arm. The vector of the prostate and seminal vesicle displacement for the rectal gas removal group was significantly smaller than in all patients. With rectal gas removal, the 95% confidence limit of the prostate displacement vector was reduced by 2.3 mm in the non-WPRT arm and 2.9 mm in the WPRT arm. The 95% confidence limit of the seminal vesicle displacement vector was reduced by 0.3 mm in the non-WPRT arm and 4.4 mm in the WPRT arm. CONCLUSIONS: Using rectal gas removal, the cross-sectional area could be decreased, resulting in reduced motion and margins for the prostate and seminal vesicles. This is especially important for WPRT patients who require RT to the prostate, seminal vesicles, and pelvic lymph nodes.


Asunto(s)
Flatulencia/diagnóstico por imagen , Movimiento (Física) , Próstata/diagnóstico por imagen , Neoplasias de la Próstata/radioterapia , Recto/diagnóstico por imagen , Análisis de Varianza , Intervalos de Confianza , Gases , Humanos , Higiene , Masculino , Movimiento , Neoplasias de la Próstata/diagnóstico por imagen , Radiografía , Planificación de la Radioterapia Asistida por Computador , Radioterapia Conformacional , Recto/anatomía & histología , Vesículas Seminales/diagnóstico por imagen , Vejiga Urinaria/anatomía & histología , Vejiga Urinaria/diagnóstico por imagen
13.
Eur J Gastroenterol Hepatol ; 19(7): 589-93, 2007 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-17556907

RESUMEN

OBSERVATION: Intestinal gas production and abdominal discomfort can be triggered by the ingestion of carbohydrates such as lactulose. Using plain abdominal radiographs, we studied whether subjective complaints after a lactulose breath test would be quantitatively related to intestinal gas volumes. METHODS: Abdominal symptoms after the breath test were quantified by a written questionnaire and gas volumes were scored in plain abdominal radiographs, in 50 consecutive patients with unexplained, irritable bowel syndrome-like symptoms. Breath excretion of hydrogen and methane was determined in all patients. RESULTS: Forty-two (84%) of the patients claimed that their post-breath test symptoms were a true replicate of their customary discomfort. Total symptom scores (sum of scores for pain/discomfort, borborygmi, bloating, diarrhea, constipation) or any specific symptom score were not significantly correlated to gas volume scores (r=-0.04; P=0.8 for total symptom score). The 13 (26%) methane producers had significantly higher mean gas volume scores compared with nonproducers (0.38 vs. 0.24; P=0.0008), but fewer symptoms (total symptom score 11.9 vs. 18.2; P=0.17). CONCLUSION: Intestinal gas volume, as scored in plain abdominal radiographs, is not correlated with abdominal discomfort after lactulose challenge. Intestinal gas may not be the major cause of abdominal discomfort following carbohydrate ingestion in patients with functional gut disorders.


Asunto(s)
Flatulencia/fisiopatología , Gases/análisis , Síndrome del Colon Irritable/fisiopatología , Lactulosa , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Pruebas Respiratorias/métodos , Femenino , Fermentación , Flatulencia/diagnóstico por imagen , Flatulencia/etiología , Humanos , Hidrógeno/metabolismo , Intestinos/diagnóstico por imagen , Intestinos/fisiopatología , Síndrome del Colon Irritable/diagnóstico por imagen , Masculino , Metano/biosíntesis , Persona de Mediana Edad , Radiografía , Índice de Severidad de la Enfermedad
14.
Am J Gastroenterol ; 102(4): 842-9, 2007 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-17397409

RESUMEN

BACKGROUND AND AIMS: Patients frequently complain of gas symptoms precipitated by meals, but the effect of early digestion on intestinal gas content remains unknown. Our aim was to determine the influence of meals on intestinal gas volume and distribution. METHODS: First, we developed a CT image analysis program, based on independent software modules, to measure gas content within the gut. The system was validated in nine healthy subjects by taking helical abdominal CT scans before and after rectal infusion of known volumes of air (100-400 mL). In 15 healthy subjects, intestinal gas distribution was measured in fast and early postcibal CT scans. The postcibal scan was taken 99 +/- 22 minutes after a 597 +/- 57 kcal meal. RESULTS: The volume of gas infused per rectum was detected with an accuracy of 100.4 +/- 3.0%. During fasting, intestinal gas volume was 94 +/- 7 mL (excluding two extreme outliers). After the meal, gas content within the gut increased by 64.7% (up to 149 +/- 21 mL, P < 0.01 vs fast) and the increment occurred in the colon (59 +/- 9 mL precibal vs 121 +/- 20 mL postcibal, P < 0.001), while other gut compartments remained unchanged. CONCLUSION: Ingestion of a meal activated gas metabolism and increased gas content within the gut. The increment occurred early, presumably prior to colonic fermentation of food substrates and was localized in the distal gut, suggesting that gas had a proximal origin and was propelled caudally.


Asunto(s)
Ingestión de Alimentos , Flatulencia/diagnóstico por imagen , Gases/metabolismo , Recto/diagnóstico por imagen , Tomografía Computarizada Espiral , Adulto , Ayuno , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estadísticas no Paramétricas
15.
Gastroenterology ; 128(3): 574-9, 2005 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-15765392

RESUMEN

BACKGROUND & AIMS: Patients reporting abdominal bloating exhibit impaired tolerance to intestinal gas loads. The aim of this study was to identify the gut compartment responsible for gas retention. METHODS: In 30 patients predominantly reporting abdominal bloating (24 with irritable bowel syndrome and 6 with functional bloating) and 22 healthy subjects, gas (nitrogen, carbon dioxide, and oxygen) was infused into the intestine for 2 hours while measuring rectal gas outflow. First, in 12 patients and 10 healthy subjects, gas transit (24 mL/min jejunal infusion labeled with 74 MBq bolus of 133 Xe) was measured by scintigraphy. Second, in groups of patients and healthy subjects, the effects of gas infusion (12 mL/min) in the jejunum versus ileum, jejunum versus cecum, and jejunum versus sham infusion (n=6 each) were compared by paired tests. RESULTS: In patients, total gut transit of gas was delayed (50% clearance time, 33 +/- 4 min vs 23 +/- 4 min in healthy subjects; P <.05) owing to impaired small bowel transit (50% clearance time, 20 +/- 2 min vs 12 +/- 3 min in healthy subjects; P <.05), whereas colonic transit was normal (50% clearance time, 13 +/- 2 min vs 11 +/- 2 min in healthy subjects; not significant). Furthermore, jejunal gas infusion in patients was associated with gas retention (329 +/- 81 mL vs 88 +/- 79 mL in healthy subjects; P <.05), whereas direct ileal or colonic infusion was not (61 +/- 103 mL and -143 +/- 87 mL retention, respectively). CONCLUSIONS: In patients reporting bloating, the small bowel is the gut region responsible for ineffective gas propulsion.


Asunto(s)
Flatulencia/etiología , Flatulencia/fisiopatología , Yeyuno/fisiopatología , Adulto , Anciano , Estudios de Casos y Controles , Femenino , Flatulencia/diagnóstico por imagen , Gases , Tránsito Gastrointestinal , Humanos , Masculino , Persona de Mediana Edad , Cintigrafía , Factores de Tiempo
16.
Am J Emerg Med ; 22(3): 214-8, 2004 May.
Artículo en Inglés | MEDLINE | ID: mdl-15138961

RESUMEN

Hepatic portal venous gas (HPVG) is a rare radiographic finding of significance. Most cases with HPVG are related to mesenteric ischemia that have been associated with extended bowel necrosis and fatal outcome. With the help of computed tomography (CT) in early diagnosis of HPVG, the clinical outcome of patients with mesenteric ischemia has improved. There has been also an increasing rate of detection of HPVG with certain nonischemic conditions. In this report, we present two cases demonstrating HPVG unrelated to mesenteric ischemia. One patient with cholangitis presented abdominal pain with local peritonitis and survived after appropriate antibiotic treatment. Laparotomy was avoided as a result of lack of CT evidence of ischemic bowel disease besides the presence of HPVG. The other case had severe enteritis. Although his CT finding preluded ischemic bowel disease, conservative treatment was implemented because of the absence of peritoneal signs or clinical toxic symptoms. Therefore, whenever HPVG is detected on CT, urgent exploratory laparotomy is only mandatory in a patient with whom intestinal ischemia or infarction is suspected on the basis of radiologic and clinical findings. On the other hand, unnecessary exploratory laparotomy should be avoided in nonischemic conditions that are usually associated with a better clinical outcome if appropriate therapy is prompted for the underlying diseases. Patients with radiographic diagnosis of HPVG should receive a detailed history review and physical examination. The patient's underlying condition should be determined to provide a solid ground for exploratory laparotomy. A flow chart is presented for facilitating the management of patients with HPVG in the ED.


Asunto(s)
Flatulencia/diagnóstico por imagen , Venas Hepáticas , Vena Porta , Tomografía Computarizada por Rayos X , Anciano , Anciano de 80 o más Años , Algoritmos , Antibacterianos/uso terapéutico , Causalidad , Colangitis/complicaciones , Terapia Combinada , Árboles de Decisión , Drenaje , Embolia Aérea , Tratamiento de Urgencia/métodos , Enteritis/complicaciones , Femenino , Flatulencia/etiología , Flatulencia/terapia , Humanos , Intubación Gastrointestinal , Isquemia/complicaciones , Masculino , Anamnesis/métodos , Oclusión Vascular Mesentérica/complicaciones , Peritonitis/complicaciones , Examen Físico/métodos , Neumatosis Cistoide Intestinal/complicaciones , Tomografía Computarizada por Rayos X/métodos , Tomografía Computarizada por Rayos X/normas
17.
Ned Tijdschr Geneeskd ; 146(7): 325-7, 2002 Feb 16.
Artículo en Holandés | MEDLINE | ID: mdl-11876038

RESUMEN

A 64-year-old man of Hindustan origin presented at the Emergency Department with symptoms which suggested stomach perforation. A chest X-ray taken with the patient in the upright position showed gas between the liver and the right hemidiaphragm. After 30 minutes the pain subsided spontaneously. The gas seen on the chest X-ray was diagnosed as Chilaiditi's sign, caused by interposition of the colon between the liver and the diaphragm. This interposition is usually asymptomatic and does not require surgical treatment.


Asunto(s)
Dolor Abdominal/etiología , Enfermedades del Colon/diagnóstico por imagen , Flatulencia/diagnóstico por imagen , Enfermedades del Colon/complicaciones , Diagnóstico Diferencial , Diafragma/diagnóstico por imagen , Flatulencia/complicaciones , Humanos , Hígado/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Radiografía , Síndrome
18.
Am J Gastroenterol ; 95(7): 1735-41, 2000 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-10925977

RESUMEN

OBJECTIVE: Ideally, the diagnosis of irritable bowel syndrome (IBS) would be achieved using a minimal number of procedures. It is presumed that bowel gas is related to IBS, and it is easily visualized by plain abdominal radiograph. In the present study, to clarify the relationship between IBS and the quantity of bowel gas, the measured bowel gas volume using plain abdominal radiographs was compared with the pathology of IBS. METHODS: Plain abdominal radiographs were digitized and transmitted to a computer (computed radiography) in 30 IBS patients and 30 normal controls. The quantity of bowel gas, determined as the pixel value on images and standardized by physique, was defined as the gas volume score (GVS). Using the mean +/- 2SD of GVS in the control group as the normal score, IBS patients were divided into three groups: high, normal, and low. To examine the sequential reproducibility of a similar quantity of bowel gas, a second plain abdominal radiography was performed about 2 months later, and the GVS were compared. The colonic transit time was determined using radiopaque markers. RESULTS: There was a strong correlation between the quantities of bowel gas measured by two independent gastroenterologists. The mean GVS of IBS patients was significantly higher than that in the control group (p < 0.001). The sequential reproducibility was recognized in all 10 IBS patients. There was no significance between colonic transit time and GVS, nor between symptoms and GVS. CONCLUSIONS: Abdominal gas was analyzed objectively by using GVS, and GVS was considered to represent a useful tool for the diagnosis of IBS.


Asunto(s)
Enfermedades Funcionales del Colon/complicaciones , Enfermedades Funcionales del Colon/diagnóstico por imagen , Flatulencia/diagnóstico por imagen , Flatulencia/etiología , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Radiografía , Reproducibilidad de los Resultados
19.
Acad Radiol ; 2(8): 667-9, 1995 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-9419622

RESUMEN

RATIONALE AND OBJECTIVES: The radiology report is the primary means of communication between the radiologist and the referring physician. A lack of precision in this report may adversely affect patient care. We examined how radiologists would define "nonspecific abdominal gas pattern" and how referring physicians would perceive the meaning. METHODS: A questionnaire was distributed to radiologists and referring physicians in Flint, Michigan. They were asked to categorize their definition or interpretation, respectively, of "nonspecific abdominal gas pattern" into "normal"; "either normal or abnormal"; or "abnormal, representing either mechanical obstruction or adynamic ileus." RESULTS: Thirty-three radiologists responded, 23 (69.7%) of whom used the term. One hundred fifty-seven referring physicians responded, 127 of whom assigned a specific definition to the term. Using a 2 x 3 chi-square test (df = 2), we found a statistically significant difference (p < .03) between the distribution of the meaning of the term between radiologists and their referring physicians. CONCLUSION: The term "nonspecific abdominal gas pattern" should be abandoned because it may signify a normal condition or a pathologic state. We found the definition to be dichotomous and asynchronous between radiologists and their referring physicians.


Asunto(s)
Gases , Radiografía Abdominal , Terminología como Asunto , Diagnóstico Diferencial , Flatulencia/diagnóstico por imagen , Humanos , Intestinos/diagnóstico por imagen , Variaciones Dependientes del Observador , Pautas de la Práctica en Medicina , Curva ROC , Radiografía Abdominal/estadística & datos numéricos , Encuestas y Cuestionarios
20.
Am J Gastroenterol ; 86(5): 599-602, 1991 May.
Artículo en Inglés | MEDLINE | ID: mdl-2028951

RESUMEN

Patients with functional bowel disorders frequently complain of bloating and abdominal pain, but no practical method is available to measure intestinal gas objectively. To evaluate a new technique, we evaluated 54 abdominal radiographs from 19 patients. A gastroenterologist and a radiologist independently outlined the intestinal gas bubbles in these films. Areas of gas bubbles were measured with a computer digitizing board. Bowel gas was also measured in 24 healthy controls, and in five emergency room patients, supine and erect radiographs were compared to evaluate the effects of position on bowel gas patterns. The two evaluators agreed well on the measured areas of bowel gas (r = 0.96), showing that this is a reliable method. Bowel gas was significantly greater in patients than in controls but did not correlate with symptoms. Bowel gas was significantly greater in supine than upright films, showing that the position of the patient must be standardized.


Asunto(s)
Gases , Intestinos/diagnóstico por imagen , Adulto , Anciano , Enfermedades Funcionales del Colon/diagnóstico por imagen , Enfermedades Funcionales del Colon/fisiopatología , Computadores , Femenino , Flatulencia/diagnóstico por imagen , Flatulencia/fisiopatología , Humanos , Intestinos/fisiopatología , Masculino , Persona de Mediana Edad , Postura , Radiografía
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