RESUMEN
Recent studies have demonstrated an association between congenital Zika virus (ZIKV) infection and microcephaly; however, to date, there have been no reports on the consequences of ZIKV infection on fetuses in twin pregnancies. Herein, we reported on the first case of a monochorionic diamniotic (MCDA) twin pregnancy having ZIKV-related microcephaly. Our findings suggested that, in an MCDA twin pregnancy, the ZIKV may cause infection in both fetuses, resulting in severe abnormalities in the central nervous system due to neural cell destruction and the disruption of the normal development processes of the brain. This case report and other similar twin cases may help to understand the pathogenesis and to confirm the etiology of ZIKV as a teratogenic microorganism.
Asunto(s)
Enfermedades en Gemelos/virología , Microcefalia/virología , Complicaciones Infecciosas del Embarazo/virología , Infección por el Virus Zika/complicaciones , Adolescente , Exotropía/congénito , Exotropía/etiología , Exotropía/patología , Femenino , Humanos , Recién Nacido , Embarazo , Infección por el Virus Zika/congénitoRESUMEN
Objetivou-se estudar a incidência da ambliopia no estrabismo horizontal. Estudaram-se 302 pacientes com eso e exotropias, sendo 245 do primeiro grupo e 57 do segundo. Além disso, subdividiram-se as esotropias em esotropias congênitas, esotropias acomodativas e esotropias näo acomodativas. A incidência da ambliopia no desvio horizontal em geral é de 54,30%, sendo sua freqüência de 59,18% na esotropia e de 33,33% na exotropia. Ao subdividir-se a esotropia, obteve-se, na esotropia congênita 63,63% de amblíopes, na acomodativa, 53,39% e na näo acomodativa 65,57%, dados mutio elevados e com grande importância em saúde pública