RESUMEN
Landry-Guillain-Barré-Strohl syndrome found in a three-days-old newborn is presented at the Mexican Navy Medical Center Hospital with an acute state after exchanges transfusion due to incompatibility of blood type was done. The case has the same clinical characteristics, such as those found by other authors in children, even though the statistics in this syndrome during the childhood and in the newborn periods are limited. It is frequent that the child dies before the diagnosis is made because motor and sensitive immaturity are present. This renders even more difficult the appropriate treatment and diagnosis, because the paralysis initiated in an ascending and progressive manner involving the spinal bulb may lead to confusion with other pathology, such as respiratory or neurological distress that may need respiratory mechanical assistance. It is very important to dissociated the relation albumin-citology of the spinal fluid to confirm the diagnosis. Corticoides do not modify the evolution of the clinical picture. In this paper we reviewed the modern ideas on pathogenesis and their possible allergic and immunologic association.
Asunto(s)
Recambio Total de Sangre/efectos adversos , Enfermedades del Recién Nacido/etiología , Polirradiculoneuropatía/etiología , Sistema del Grupo Sanguíneo ABO , Enfermedad Aguda , Incompatibilidad de Grupos Sanguíneos/terapia , Humanos , Recién Nacido , Enfermedades del Recién Nacido/sangre , Enfermedades del Recién Nacido/líquido cefalorraquídeo , Masculino , Polirradiculoneuropatía/sangre , Polirradiculoneuropatía/líquido cefalorraquídeoAsunto(s)
Eclampsia/líquido cefalorraquídeo , Inmunoglobulinas/líquido cefalorraquídeo , Enfermedades del Recién Nacido/líquido cefalorraquídeo , Adulto , Eclampsia/inmunología , Femenino , Humanos , Recién Nacido , Enfermedades del Recién Nacido/inmunología , Discapacidad Intelectual/líquido cefalorraquídeo , Discapacidad Intelectual/inmunología , Masculino , Embarazo , Convulsiones/líquido cefalorraquídeo , Convulsiones/inmunología , SíndromeAsunto(s)
Enfermedades del Recién Nacido/líquido cefalorraquídeo , Meningitis/líquido cefalorraquídeo , Punción Espinal/efectos adversos , Bacterias/aislamiento & purificación , Humanos , Lactante , Recién Nacido , Meningitis/microbiología , Oxígeno/sangre , Estudios Retrospectivos , Sepsis/líquido cefalorraquídeo , Sepsis/microbiologíaAsunto(s)
Flavobacterium , Enfermedades del Recién Nacido/microbiología , Meningitis/microbiología , Sepsis/microbiología , Antibacterianos/farmacología , Líquido Cefalorraquídeo/microbiología , Farmacorresistencia Microbiana , Flavobacterium/efectos de los fármacos , Humanos , Recién Nacido , Enfermedades del Recién Nacido/líquido cefalorraquídeo , MasculinoAsunto(s)
Humanos , Flavobacterium/efectos de los fármacos , Sepsis/microbiología , Meningitis/microbiología , Farmacorresistencia Microbiana , Líquido Cefalorraquídeo/microbiología , Enfermedades del Recién Nacido/líquido cefalorraquídeo , Enfermedades del Recién Nacido/microbiología , Antibacterianos/farmacologíaRESUMEN
The characteristics of the cytochemistry of the spinal fluid (LCR) were evaluated in 123 newborns that were divided into four groups according to their postnatal age. Following this, proteins were 103.25 +/- 49.05; 85.09 +/- 41.89; 66.31 +/- 43.44 and 55.38 +/- 20.91 mg/100 ml. respectively for the 10, 20, 30 and 50 days of life groups, with significant differenece (p less than 0.01) of the first group with the third and fourth. Values for glucose fluctuated form 53.56 +/- 20.32 mg/100 ml. to 63.16 +/- 22.80 for the different groups, but without statistical difference among them. A similar situation was found with the number of cells that fluctuated as an average form 4.28 to 7.38 mm3. Finally, the results from other work groups are reported showing similar outcome as ours.
Asunto(s)
Líquido Cefalorraquídeo/análisis , Recién Nacido , Factores de Edad , Proteínas del Líquido Cefalorraquídeo/análisis , Glucosa/líquido cefalorraquídeo , Humanos , Enfermedades del Recién Nacido/líquido cefalorraquídeoRESUMEN
Results of CSF examinations from 117 high-risk neonates were reviewed. The mean CSF cell count was 8.4 cells/mm3 and the range was 0 to 32 cells/mm.3 Approximately 60% of the CSF WBC were polymorphonuclear leukocytes. Average CSF protein concentrations were 90 mg/dl (range, 20-170 mg/dl) in term and 115 mg/dl (range, 65-150 mg/dl) in preterm infants. The average CSF glucose was 81% of the blood glucose value in term and 74% in preterm infants. Comparison of these CSF findings with those from 119 infants with bacterial meningitis revealed that there was considerable overlapping of values, but only one of the 119 infants with meningitis had a completely normal initial CSF examination. The decision to initiate antimicrobial therapy in neonates with suspected meningitis must be based on total evaluation of the patient.