RESUMEN
PURPOSE: To investigate the relationship between the kinematics of spontaneous blinks and the anterior area of the levator palpebrae superioris muscle in patients with Graves orbitopathy (GO). METHODS: This is a case-control study. The authors measured the margin reflex distance of the upper eyelid (margin reflex distance 1), the kinematics of spontaneous blinks, and the anterior area of levator palpebrae superioris muscle in CT coronal scans of patients with Graves upper eyelid retraction (GO) and a control group. The eye with the greatest margin reflex distance 1 was selected for analysis in each group. RESULTS: A total of 68 participants were included, with 36 in the GO group and 32 in the control group. In the GO group, the mean margin reflex distance 1 measured 6.5 mm, while in the control group, it was 3.9 mm. Almost all parameters related to the closing phase of spontaneous blinking activity, including amplitude, velocity, blinking rate, and interblink time, did not differ between the two groups. However, the effectiveness of the blink's amplitude (ratio of blink amplitude to margin reflex distance 1) and the main sequence (relationship between amplitude and velocity) were significantly reduced in the GO group compared with the control group. The area of the levator palpebrae superioris muscle was significantly larger in GO than in controls, with 71.4% of patients' muscles outside of the maximum range of the controls. CONCLUSIONS: In patients with GO, there is a reduction in blinking effectiveness, also known as blink lagophthalmos, which is a factor in the common occurrence of ocular surface symptoms. The increase in velocity with amplitude is also reduced in GO.
Asunto(s)
Parpadeo , Párpados , Oftalmopatía de Graves , Músculos Oculomotores , Humanos , Parpadeo/fisiología , Femenino , Oftalmopatía de Graves/fisiopatología , Oftalmopatía de Graves/complicaciones , Oftalmopatía de Graves/diagnóstico , Masculino , Persona de Mediana Edad , Músculos Oculomotores/fisiopatología , Adulto , Estudios de Casos y Controles , Párpados/fisiopatología , Enfermedades de los Párpados/fisiopatología , Enfermedades de los Párpados/diagnóstico , Anciano , Tomografía Computarizada por Rayos X , LagoftalmosRESUMEN
Pemphigus foliaceus (PF) is an autoimmune blistering disorder which affects the superficial layers of the epidermis with rare mucosal involvement. We present the case of a 12-year-old girl with PF involving the eyes and eyelids. A literature review of pediatric nonendemic PF revealed another two cases with ocular manifestations. Eyelid involvement is an uncommon feature of PF that should be properly identified and treated.
Asunto(s)
Enfermedades de los Párpados , Pénfigo , Niño , Femenino , Humanos , Enfermedades de los Párpados/diagnóstico , Enfermedades de los Párpados/patología , Párpados/patología , Pénfigo/diagnóstico , Pénfigo/patologíaRESUMEN
PURPOSE: To assess the sensitivity and specificity of lateral midpupil lid distances for the detection of upper lid lateral flare. METHODS: Lateral lid flare was determined by unanimous agreement among six experienced oculoplastic surgeons in the grading of photographs obtained for patients with Graves orbitopathy (GO). Bézier lines were employed to extract the upper eyelid contours of the patients and a control group of age and sex matched subjects. Custom software was employed to determine 5 lateral midpupil eyelid distances. The sensitivity and specificity of each measurement in detecting lateral flare were estimated from receiver operating characteristic curves. The non-parametric Kruskal-Wallis one-way analysis of variance (ANOVA) with Dunn's posthoc test was used to compare the median values of the contour parameters between groups. RESULTS: The degree of agreement between judges evaluated with the Fleiss' Kappa test was relatively high (K = 0.69, z = 16.6, p < .0001). The raters classified 12 lids with lateral lid flare (LLF) and 7 without LLF in patients with GO. There was no agreement on the presence or absence of LLF in 11 lids. In all eyes, lateral midpupil lid distances diminished from the center of the eyelid towards the lateral canthus. Receiver operating characteristic analysis for the midpupil distances revealed that the fourth distance from the center demonstrated high sensitivity and specificity in detecting flare. At this location (2.5 mm medial to the lateral canthus) a midpupil distance equal to or greater than 60% of the margin reflex distance (MRD1) indicated the presence of flare. CONCLUSIONS: - A single measurement of a lateral midpupil eyelid distance 2.5 mm medial to the lateral canthus is a sensitive and specific measurement for the diagnosis of the LLF.
Asunto(s)
Enfermedades de los Párpados/diagnóstico , Párpados/diagnóstico por imagen , Oftalmopatía de Graves/diagnóstico , Aparato Lagrimal/diagnóstico por imagen , Estudios Transversales , Enfermedades de los Párpados/etiología , Oftalmopatía de Graves/complicaciones , HumanosRESUMEN
OBJECTIVE: To compare the measurement of the meibomian gland (MG) dropout between two infrared meibographers in patients with and without dry eye. METHODS: The right eyelids of each patient were imaged using the Antares and Cobra meibography devices. All images were analyzed using Phoenix software to calculate the percentage of the MG dropout. Lipid layer thickness, eyelid margin characteristics, ocular surface staining, MG secretion, number of expressible glands, and noninvasive tear breakup time were also evaluated. A comparison between nondry eye and evaporative dry eye was performed. RESULTS: Eighty participants (mean age, 36.93 years and 51.3% women) were included, of which 67.5% had nondry eye. A significant difference was observed in the dropout percentage of the superior eyelid between the Antares and Cobra devices (P=0.007) for all participants and when only the nondry eye patients were examined. In patients with dry eye, no significant differences were found in the dropout measurements of both eyelids. CONCLUSIONS: Statistically significant differences in the MG dropout percentage in the upper eyelid of nondry eye patients were obtained from both meibographers. The measurements were similar in patients with dry eye, suggesting that the two instruments can be interchanged.
Asunto(s)
Síndromes de Ojo Seco , Enfermedades de los Párpados , Adulto , Síndromes de Ojo Seco/diagnóstico , Enfermedades de los Párpados/diagnóstico , Femenino , Humanos , Lípidos , Masculino , Glándulas Tarsales/diagnóstico por imagen , Coloración y Etiquetado , LágrimasRESUMEN
RESUMO A amiloidose é caracterizada pela deposição extracelular de fibrilas amiloides proteicas nos tecidos, incluindo conjuntiva, motivada por sua insolubilidade em proteínas proteolíticas. A amiloidose conjuntival, afetando especificamente a conjuntiva palpebral, é um achado raro na prática clínica. Os autores descrevem um caso de um paciente do sexo masculino, caucasiano, de 71 anos, apresentando lesões bilaterais localizadas na conjuntiva da pálpebra inferior, elevadas, bem delimitadas, amareladas, aliadas a pálpebras desestabilizadas. Foi realizada excisão cirúrgica das lesões, e o exame histológico confirmou se tratar de amiloidose conjuntival. Não houve recorrência após o procedimento. A amiloidose conjuntival afetando ambas as pálpebras inferiores é um achado raro na literatura. O manejo da amiloidose conjuntival depende da extensão do envolvimento local e do status sistêmico do paciente, variando de sintomático, com o uso de lubrificantes, até cirúrgico, com a remoção das lesões.
ABSTRACT Amyloidosis is characterized by extracellular deposition of protein amyloid fibrils in tissues, including conjunctiva, which are insoluble in proteolytic proteins. Conjunctival amyloidosis specifically in the palpebral conjunctiva is a rare finding in clinical practice. The authors described the case of a 71-year-old caucasian male patient, with bilateral lesions located in the lower eyelid conjunctiva, elevated, well-defined, yellowish, combined with destabilized eyelids. Surgical excision of the lesions was performed, and the histological examination confirmed conjunctival amyloidosis. There was no recurrence after the procedure. Conjunctival amyloidosis in both lower eyelids is a rare finding in the literature. The management of conjunctival amyloidosis depends on the extent of local involvement and patient's general health status, varying from symptomatic, with use of ocular lubricants, to surgical, by removing the lesions.
Asunto(s)
Humanos , Masculino , Anciano , Enfermedades de la Conjuntiva/diagnóstico , Enfermedades de los Párpados/diagnóstico , Amiloidosis/diagnóstico , Biopsia , Conjuntiva/patología , Párpados/patologíaAsunto(s)
Dermatitis Alérgica por Contacto/diagnóstico , Dispositivos de Protección de los Ojos/efectos adversos , Enfermedades de los Párpados/diagnóstico , Natación , Adolescente , Dermatitis Alérgica por Contacto/etiología , Enfermedades de los Párpados/etiología , Párpados/fisiopatología , Femenino , HumanosRESUMEN
PURPOSE: To describe 26 cases of bulbar conjunctival sporotrichosis. METHODS: Review of clinical records of patients with bulbar conjunctivitis due to culture-proven Sporothrix spp. infection, in Rio de Janeiro, from 2007 to 2017. RESULTS: Twenty-six patients were identified. Median age was 25 years. Adults were more affected (53.8%), followed by adolescents (26.9%). There was a predominance of women (73.1%). Twenty-four patients (96%) reported contact with cats with sporotrichosis. Twenty-one patients (80.8%) presented a primary ocular sporotrichosis. Five patients presented associated eyelid lesions, and 21 (80.8%) tarsal conjunctivitis. Parinaud oculoglandular syndrome was observed in 17 (81%) patients. Eight patients (36.4%) reported the use of steroid drops before diagnosis was made. All patients but one were treated with oral itraconazole. Twenty-three patients (88.5%) were completely cured and three (11.5%) were lost to follow-up. Eight patients (34.8%) developed ocular sequelae. CONCLUSION: Bulbar conjunctivitis is an important clinical presentation of ocular sporotrichosis. It can lead to ocular sequelae. Sporotrichosis should be considered in the differential diagnosis of ophthalmic external diseases, especially in patients with cat contact history.
Asunto(s)
Conjuntivitis/microbiología , Enfermedades Endémicas/estadística & datos numéricos , Infecciones Fúngicas del Ojo/microbiología , Enfermedades de los Párpados/microbiología , Sporothrix/aislamiento & purificación , Esporotricosis/microbiología , Zoonosis/microbiología , Administración Oral , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Animales , Antifúngicos/uso terapéutico , Brasil/epidemiología , Niño , Conjuntivitis/diagnóstico , Conjuntivitis/tratamiento farmacológico , Conjuntivitis/epidemiología , Infecciones Fúngicas del Ojo/diagnóstico , Infecciones Fúngicas del Ojo/tratamiento farmacológico , Infecciones Fúngicas del Ojo/epidemiología , Enfermedades de los Párpados/diagnóstico , Enfermedades de los Párpados/tratamiento farmacológico , Enfermedades de los Párpados/epidemiología , Femenino , Humanos , Itraconazol/uso terapéutico , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Esporotricosis/diagnóstico , Esporotricosis/tratamiento farmacológico , Esporotricosis/epidemiología , Adulto Joven , Zoonosis/diagnóstico , Zoonosis/tratamiento farmacológico , Zoonosis/epidemiologíaRESUMEN
Introdução: A reconstrução de pálpebra inferior representa um desafio peculiar ao cirurgião plástico, uma vez que traduz uma região facial de importância estética e funcional. O objetivo é apresentar uma técnica opcional para a reconstrução de defeitos da pálpebra inferior com o retalho cutâneo zigomáticopalpebral. Esta técnica mostra uma alternativa nos casos de pele escleroatrófica de pessoas idosas, bem como para pessoas jovens, que não apresentam redundância da pele palpebral superior, impossibilitando por exemplo o uso de enxertos de pálpebra superior ou retalhos como o de Fricke ou Tripier. Métodos: Os autores mostram a indicação do retalho em casos de ectrópio cicatricial, reconstrução após ressecção de neoplasias, associação com outros retalhos como de Hughes ou para cobertura de enxertos cartilaginosos. É um retalho de transposição composto por pele e subcutâneo, randomizado. A técnica baseia-se no uso de retalho local, de características muito semelhantes à área do defeito, o que permite mimetização, segurança e exequibilidade. Resultados: Os resultados imediatos e tardios são satisfatórios e bem aceitos pelos pacientes e pela equipe cirúrgica em termos estéticos e funcionais, com oclusão palpebral adequada e lubrificação ocular preservada. Conclusão: O retalho zigomático-palpebral apresenta como vantagens a simplicidade de execução, sangramento mínimo, baixa morbidade de área doadora e feito sob anestesia local. O objetivo de reconstruir defeitos da pálpebra é restaurar a anatomia e função. Esta pode ser uma tarefa desafiadora, especialmente em defeitos maiores que podem estar presentes nos procedimentos oncológicos em jovens e em idosos com pele escleroatrófica e mínima frouxidão.
Introduction: Lower eyelid reconstruction represents a unique challenge to plastic surgeons, since it involves a facial region of aesthetic and functional importance. The objective is to present an optional technique for the reconstruction of lower eyelid defects using zygomatic-palpebral skin flap. This technique represents an alternative in cases of scleroatrophic skin in older patients, and for young people who do not have an upper eyelid skin redundancy, which prevents, for example, the use of upper eyelid grafts or flaps such as those of Fricke or Tripier. Methods: The authors describe the flap used in cases of cicatricial ectropion and reconstruction after resection of neoplasms and association with other flaps, such as those of Hughes, or for coverage of cartilage grafts. The flap consisted of a transposition flap made up of skin and underlying subcutaneous tissues, randomized . The technique was based on the use of a local flap with highly similar characteristics to the defect area, which allowed it to mimic functions, while being safe and feasible. Results: The immediate and late results in terms of aesthetics and function were satisfactory and well accepted by patients and the surgical team, with adequate eyelid occlusion and preserved ocular lubrication. Conclusion: The advantages of the zygomatic-palpebral flap are its ease of execution, minimal bleeding, low morbidity of the donor area, and the use of local anesthesia. The reconstruction of eyelid defects aims to restore anatomy and function. This can be a challenging task, especially in cases with larger defects that may be present after oncologic procedures both in young and old patients presenting with scleroatrophic skin and minimal tissue laxity.
Asunto(s)
Humanos , Adulto , Persona de Mediana Edad , Anciano , Colgajos Quirúrgicos/cirugía , Colgajos Quirúrgicos/efectos adversos , Conjuntiva/anatomía & histología , Conjuntiva/cirugía , Enfermedades de la Conjuntiva/cirugía , Procedimientos de Cirugía Plástica/efectos adversos , Procedimientos de Cirugía Plástica/métodos , Ojo , Enfermedades de los Párpados/cirugía , Enfermedades de los Párpados/complicaciones , Enfermedades de los Párpados/diagnóstico , Párpados/cirugíaRESUMEN
RESUMEN Se presentó un caso operado de ptosis palpebral severa del ojo izquierdo, en un paciente de 83 años de edad, chofer profesional. el mismo fue corregido mediante la técnica de Fox, fijando el párpado superior al músculo frontal con una banda de silicona de 1 mm de ancho. Se presentaron los buenos resultados de esta cirugía correctiva en el trans-operatorio y post-operatorio de 7 días y al mes. Se mostraron resultados satisfactorios visual y estético con el uso de la misma. No se reportó reacción adversa a la banda de silicona. Se recomienda extender el uso de esta técnica a todos los servicios de la provincia. Continuar el perfeccionamiento de la misma en el servicio (AU).
ABSTRACT An 83 years old patient, professional driver, operated of a severe ptosis in the left eye, is corrected by Fox procedure, fixating the upper eyelid to the frontal muscle with a silicone band of 1 mm. The good corrective results, during surgery, after that, at 7 days and at a month, are showed as a great achievement in visual and aesthetic fields. There was not allergic reaction to the silicone material. We recommend to extend the use of this procedure to all provinces services and to continue the improvement of the procedure in our service (AU).
Asunto(s)
Humanos , Masculino , Anciano , Blefaroptosis/cirugía , Extracción de Catarata/efectos adversos , Implantación de Lentes Intraoculares/efectos adversos , Enfermedades de los Párpados/diagnóstico , Rehabilitación , Blefaroptosis/diagnósticoRESUMEN
RESUMEN Se presentó un caso operado de ptosis palpebral severa del ojo izquierdo, en un paciente de 83 años de edad, chofer profesional. el mismo fue corregido mediante la técnica de Fox, fijando el párpado superior al músculo frontal con una banda de silicona de 1 mm de ancho. Se presentaron los buenos resultados de esta cirugía correctiva en el trans-operatorio y post-operatorio de 7 días y al mes. Se mostraron resultados satisfactorios visual y estético con el uso de la misma. No se reportó reacción adversa a la banda de silicona. Se recomienda extender el uso de esta técnica a todos los servicios de la provincia. Continuar el perfeccionamiento de la misma en el servicio (AU).
ABSTRACT An 83 years old patient, professional driver, operated of a severe ptosis in the left eye, is corrected by Fox procedure, fixating the upper eyelid to the frontal muscle with a silicone band of 1 mm. The good corrective results, during surgery, after that, at 7 days and at a month, are showed as a great achievement in visual and aesthetic fields. There was not allergic reaction to the silicone material. We recommend to extend the use of this procedure to all provinces services and to continue the improvement of the procedure in our service (AU).
Asunto(s)
Humanos , Masculino , Anciano , Blefaroptosis/cirugía , Extracción de Catarata/efectos adversos , Implantación de Lentes Intraoculares/efectos adversos , Enfermedades de los Párpados/diagnóstico , Rehabilitación , Blefaroptosis/diagnósticoRESUMEN
PURPOSE: To assess ocular surface disease (OSD) in glaucoma using clinical parameters, self-report assessment, and keratograph analysis. METHODS: A total of 30 glaucoma patients and 27 subjects with cataracts (control group) were enrolled in the study. Only glaucoma patients who were using at least 1 topical intraocular pressure-lowering medication were included. An ophthalmological examination was performed, including tear break-up time (BUT), assessment of conjunctival hyperemia and keratitis, and completion of the Ocular Surface Disease Index (OSDI) questionnaire. All the patients underwent keratograph analysis including noninvasive BUT, meibography, tear meniscus height, and redness scale. Quality of life was also assessed in all the patients using National Eye Institute Visual Function Questionnaire (NEI VFQ)-25. The comparison of OSD between the 2 groups was assessed. RESULTS: There was a significant difference in OSD: keratitis and conjunctival hyperemia were worse in the glaucoma group (P=0.009 and 0.008, respectively). The glaucoma group had significantly worse scores on the OSDI questionnaire (32.53±20.75 vs. 20.42±18.77; P=0.007). For the keratograph assessment, the glaucoma group had significantly smaller tear meniscus height (0.22±0.08 vs. 0.24±0.04, respectively; P=0.041); worse bulbar redness (2.06±0.67 vs. 1.70±0.45, respectively; P=0.021); higher meibography grades (2.34±1.01 vs. 1.52±0.64, respectively; P=0.001); and worse noninvasive keratograph tear BUT (5.45±4.16 vs. 8.40±5.65, respectively; P=0.023). Patients with glaucoma had a worse quality of life (60.73±18.25 vs. 76.62±8.03, respectively; P=0.039). CONCLUSIONS: Our findings not only confirm the high prevalence of clinical findings of OSD in glaucoma patients but also reveal new objective parameters measured by keratograph analysis.
Asunto(s)
Enfermedades de la Conjuntiva/diagnóstico , Enfermedades de los Párpados/diagnóstico , Glaucoma de Ángulo Abierto/diagnóstico , Hiperemia/diagnóstico , Queratitis/diagnóstico , Glándulas Tarsales/patología , Anciano , Antihipertensivos/uso terapéutico , Estudios Transversales , Femenino , Glaucoma de Ángulo Abierto/tratamiento farmacológico , Glaucoma de Ángulo Abierto/fisiopatología , Humanos , Presión Intraocular/fisiología , Masculino , Persona de Mediana Edad , Autoinforme , Perfil de Impacto de Enfermedad , Encuestas y Cuestionarios , Tonometría Ocular , Agudeza Visual/fisiologíaAsunto(s)
Azitromicina/administración & dosificación , Chlamydia trachomatis/aislamiento & purificación , Enfermedades de los Párpados/diagnóstico , Párpados/patología , Tracoma/diagnóstico , Administración Oral , Antibacterianos/administración & dosificación , Niño , Diagnóstico Diferencial , Enfermedades de los Párpados/tratamiento farmacológico , Enfermedades de los Párpados/microbiología , Párpados/microbiología , Humanos , Masculino , Tracoma/tratamiento farmacológico , Tracoma/microbiologíaAsunto(s)
Humanos , Lactante , Preescolar , Niño , Adolescente , Enfermedades de los Párpados/diagnóstico , Párpados/anomalíasRESUMEN
Objetivo: determinar la efectividad del sondaje intraductal en el tratamiento de la disfunción de las glándulas de Meibomio. Métodos: se realizó un estudio descriptivo, longitudinal, prospectivo, en el Instituto Cubano de Oftalmología Ramón Pando Ferrer, en el período de marzo del año 2014 al mismo mes del año 2015 en 50 ojos (25 pacientes) con diagnóstico de disfunción de las glándulas de Meibomio, a los que se les realizó el sondaje intraductal. Resultados: el tiempo de ruptura de la película lagrimal preoperatorio mínimo fue de 1 segundo y el máximo de 9; al mes y a los seis meses el tiempo de ruptura de la película lagrimal mínimo era de 9 segundos y el máximo de 13. En el preoperatorio los 50 ojos tuvieron tiempo de ruptura de la película lagrimal Ë 10 segundos; en cambio, al mes y a los seis meses el 50 por ciento tenían tiempo de ruptura de la película lagrimal de ≥ 10 segundos. El índice de enfermedad de la superficie ocular preoperatorio fue 87,80 ± 9,48; a la semana 64,00 ± 10,20; al mes 35,30 ± 9,55 y a los seis meses 36,10 ± 10,37, con diferencia significativa con respecto al preoperatorio ( p= 0,000); no entre el posoperatorio de uno y seis meses (p= 0,6135). Los lubricantes fueron necesarios en todos antes y después del procedimiento; pero al mes y a los seis meses todos los usaban con menor frecuencia. No hubo complicaciones; 5 ojos (10 por ciento) necesitaron un segundo tratamiento y el tiempo promedio fue de 4,4 meses. Conclusiones: el sondaje intraductal de las glándulas de Meibomio es un procedimiento único, seguro, con baja necesidad de retratamiento, que reduce la necesidad del uso de lubricantes, por lo que es un tratamiento efectivo en la disfunción de estas(AU)
Objective: to determine the effectiveness of intraductal probing in treatment of Meibonian gland dysfunction. Methods: a prospective, longitudinal and descriptive study was conducted in 50 eyes (25 patients), who had been diagnosed as Meibonian gland dysfunction and performed the intraductal probing at Ramon Pando Ferrer Cuban Institute of Ophthalmology in the period March 2014 to March 2015. Results: the minimal length of time of rupture of the lachrymal film before surgery was one second and the maximum 9 seconds; after one month and six months the minimal value was 9 seconds and the maximum value was 13. In the preoperative period, 50 eyes showed length of time of rupture of the lachrymal film below 10 seconds; however, one month and six months later, 50 percent of patients had length of time of rupture of the lachrymal film equal or over 10 seconds. The preoperative index of disease of the ocular surface was 87.80 ± 9.48; after one week was 64.00 ± 10.20; after one month 35.30 ± 9.55 and after six months 36.10 ± 10.37, with significant difference in the preoperative (p= 0.000); but it was non-significant between the postoperative term at one month and at six months (p= 0.6135). Oils were necessary in all the eyes before and after the surgical procedure; however, one month and six months later, all the patients used them less frequently. There were no complications, five eyes (10 percent) required a second treatment and the average time elapsed was 4.4 months(AU) Conclusions: the intraductal Meibonian gland probing is a safe, single procedure with almost no requirement for retreatment, which reduces the need for the use of oils and is and effective therapy for Meibonian gland dysfunction.
Asunto(s)
Humanos , Enfermedades de los Párpados/diagnóstico , Gotas Lubricantes para Ojos/uso terapéutico , Glándulas Tarsales/lesiones , Sonda de Prospección , Epidemiología Descriptiva , Estudios Longitudinales , Estudios ProspectivosRESUMEN
Objetivo: determinar la efectividad del sondaje intraductal en el tratamiento de la disfunción de las glándulas de Meibomio. Métodos: se realizó un estudio descriptivo, longitudinal, prospectivo, en el Instituto Cubano de Oftalmología Ramón Pando Ferrer, en el período de marzo del año 2014 al mismo mes del año 2015 en 50 ojos (25 pacientes) con diagnóstico de disfunción de las glándulas de Meibomio, a los que se les realizó el sondaje intraductal. Resultados: el tiempo de ruptura de la película lagrimal preoperatorio mínimo fue de 1 segundo y el máximo de 9; al mes y a los seis meses el tiempo de ruptura de la película lagrimal mínimo era de 9 segundos y el máximo de 13. En el preoperatorio los 50 ojos tuvieron tiempo de ruptura de la película lagrimal Ë 10 segundos; en cambio, al mes y a los seis meses el 50 por ciento tenían tiempo de ruptura de la película lagrimal de ≥ 10 segundos. El índice de enfermedad de la superficie ocular preoperatorio fue 87,80 ± 9,48; a la semana 64,00 ± 10,20; al mes 35,30 ± 9,55 y a los seis meses 36,10 ± 10,37, con diferencia significativa con respecto al preoperatorio ( p= 0,000); no entre el posoperatorio de uno y seis meses (p= 0,6135). Los lubricantes fueron necesarios en todos antes y después del procedimiento; pero al mes y a los seis meses todos los usaban con menor frecuencia. No hubo complicaciones; 5 ojos (10 por ciento) necesitaron un segundo tratamiento y el tiempo promedio fue de 4,4 meses. Conclusiones: el sondaje intraductal de las glándulas de Meibomio es un procedimiento único, seguro, con baja necesidad de retratamiento, que reduce la necesidad del uso de lubricantes, por lo que es un tratamiento efectivo en la disfunción de estas(AU)
Objective: to determine the effectiveness of intraductal probing in treatment of Meibonian gland dysfunction. Methods: a prospective, longitudinal and descriptive study was conducted in 50 eyes (25 patients), who had been diagnosed as Meibonian gland dysfunction and performed the intraductal probing at Ramon Pando Ferrer Cuban Institute of Ophthalmology in the period March 2014 to March 2015. Results: the minimal length of time of rupture of the lachrymal film before surgery was one second and the maximum 9 seconds; after one month and six months the minimal value was 9 seconds and the maximum value was 13. In the preoperative period, 50 eyes showed length of time of rupture of the lachrymal film below 10 seconds; however, one month and six months later, 50 percent of patients had length of time of rupture of the lachrymal film equal or over 10 seconds. The preoperative index of disease of the ocular surface was 87.80 ± 9.48; after one week was 64.00 ± 10.20; after one month 35.30 ± 9.55 and after six months 36.10 ± 10.37, with significant difference in the preoperative (p= 0.000); but it was non-significant between the postoperative term at one month and at six months (p= 0.6135). Oils were necessary in all the eyes before and after the surgical procedure; however, one month and six months later, all the patients used them less frequently. There were no complications, five eyes (10 percent) required a second treatment and the average time elapsed was 4.4 months(AU) Conclusions: the intraductal Meibonian gland probing is a safe, single procedure with almost no requirement for retreatment, which reduces the need for the use of oils and is and effective therapy for Meibonian gland dysfunction.
Asunto(s)
Humanos , Enfermedades de los Párpados/diagnóstico , Gotas Lubricantes para Ojos/uso terapéutico , Glándulas Tarsales/lesiones , Sonda de Prospección , Epidemiología Descriptiva , Estudios Longitudinales , Estudios ProspectivosRESUMEN
Abstract The authors report a case of unilateral floppy eyelid syndrome with ipsilateral intolerance to brimonidine in a 65-year-old man. The singularity of this case is the combination of two rare illnesses of great phlogistic potentiality in the same eye. The purpose of this article is to report a case of unilateral floppy eyelid syndrome with ipsilateral intolerance to brimonidine, emphasizing a possible relation between them. The result was a unilateral keratopathy that emulated an intraepithelial neoplasia. The key to solving the problem was an unexplained anterior uveitis that raised the suspicion of drug toxicity.The upper eyelid eversion of the affected eye during sleep seemed to be the common denominator of both ailments. The bizarre aspect of the epitheliopathy most likely resulted from the combination of trauma, insufficient lubrication, and drug intolerance.
Resumo Os autores relatam um caso de síndrome da pálpebra flácida unilateral com intolerância ipsilateral à brimonidina em um homem de 65 anos de idade. A singularidade deste caso é a combinação de duas doenças raras de grande potencialidade inflamatória no mesmo olho. O objetivo deste artigo é relatar um caso de síndrome da pálpebra flácida com intolerância ipsilateral à brimonidina, enfatizando uma possível relação entre eles. O resultado foi uma ceratopatia unilateral que simulou uma neoplasia intra-epitelial. A chave para resolver o problema foi uma uveíte anterior inexplicável que levantou a suspeita de toxicidade medicamentosa. A eversão da pálpebra superior do olho afetado durante o sono parece ser o denominador comum de ambas as doenças. O aspecto bizarro da epiteliopatia provavelmente resultou da combinação de trauma, lubrificação insuficiente e intolerância ao medicamento.
Asunto(s)
Humanos , Masculino , Anciano , Uveítis Anterior/inducido químicamente , Enfermedades de los Párpados/complicaciones , Enfermedades de los Párpados/diagnóstico , Enfermedades de los Párpados/terapia , Tartrato de Brimonidina/efectos adversos , Soluciones Oftálmicas , Fluorometolona/uso terapéutico , Carboximetilcelulosa de Sodio/uso terapéutico , Glaucoma/tratamiento farmacológico , Enfermedades de la Córnea/etiología , Tartrato de Brimonidina/uso terapéutico , Microscopía con Lámpara de HendiduraRESUMEN
Eyelid retraction, has received limited attention and it has passively been interpreted as the result of an overactive levator palpebrae superioris muscle secondary to midbrain injury. However, eyelid retractions can occur in other neurological diseases, not directly related with the midbrain. We report three patients who developed eyelid retraction. One patient had a bilateral eyelid retraction, related with Creutzfeldt-Jakob disease (CJD). Another patient had a unilateral right eyelid retraction associated with a thalamic-mesencephalic infarct. The third patient had a bilateral pontine infarction on magnetic resonance imaging. In the patient with CJD, eyelid retraction did not subside. Among patients with infarctions, the retraction persisted after focal symptoms had subsided, showing an evolution that was apparently independent of the basic process. The analysis of these patients allows us to conclude that the pathogenesis of eyelid retraction includes supranuclear mechanisms in both the development and maintenance of the phenomenon. Unilateral or bilateral eyelid retraction does not alter the normal function of eyelid, which ever had normal close eye blink. In these reported cases, a hyperactivity of levator palpebrae superioris muscle was clinically ruled out.
Asunto(s)
Infarto Encefálico/complicaciones , Síndrome de Creutzfeldt-Jakob/complicaciones , Enfermedades de los Párpados/etiología , Enfermedades Musculares/complicaciones , Músculos Oculomotores , Adulto , Infarto Encefálico/diagnóstico por imagen , Síndrome de Creutzfeldt-Jakob/diagnóstico por imagen , Enfermedades de los Párpados/diagnóstico , Femenino , Humanos , Imagen por Resonancia Magnética , Persona de Mediana EdadRESUMEN
Eyelid retraction, has received limited attention and it has passively been interpreted as the result of an overactive levator palpebrae superioris muscle secondary to midbrain injury. However, eyelid retractions can occur in other neurological diseases, not directly related with the midbrain. We report three patients who developed eyelid retraction. One patient had a bilateral eyelid retraction, related with Creutzfeldt-Jakob disease (CJD). Another patient had a unilateral right eyelid retraction associated with a thalamic-mesencephalic infarct. The third patient had a bilateral pontine infarction on magnetic resonance imaging. In the patient with CJD, eyelid retraction did not subside. Among patients with infarctions, the retraction persisted after focal symptoms had subsided, showing an evolution that was apparently independent of the basic process. The analysis of these patients allows us to conclude that the pathogenesis of eyelid retraction includes supranuclear mechanisms in both the development and maintenance of the phenomenon. Unilateral or bilateral eyelid retraction does not alter the normal function of eyelid, which ever had normal close eye blink. In these reported cases, a hyperactivity of levator palpebrae superioris muscle was clinically ruled out.