RESUMEN
INTRODUCTION: Intra-abdominal calcifications (iAC) detected during fetal ultrasound examinations are characterized by their isolated or associated nature, as well as their location. Our objective was to describe all cases of isolated iAC along with their etiological investigations and neonatal outcome, during a 10-year practice in a referral center. METHODS: We conducted a retrospective descriptive monocentric study on neonates diagnosed with isolated iAC after antenatal expert ultrasound scan and referred to the Multidisciplinary Center for Prenatal Diagnosis at Trousseau Hospital and born between January 1st, 2008 and June 30th, 2018. The exclusion criteria were: retroperitoneal calcifications, iAC associated with other digestive abnormalities or with congenital malformations. RESULTS: The 32 isolated iAC cases accounted for 46% of all iAC. Nine cases were excluded for missing neonatal data. Among the 23 remaining isolated iAC cases, we observed 15 intra-hepatic calcifications, 5 peri-hepatic and two peritoneal calcifications. One fetus had both intra- and peri-hepatic calcifications. The majority of iAC remained stable throughout pregnancy. No cases of aneuploidy, fetal infection, or cystic fibrosis were detected. The neonatal outcome was favorable in all cases. CONCLUSIONS: In case of isolated and stable iAC after expert ultrasound scan, after having ruled out infectious diseases of the fetus and looked for the most frequent mutations of cystic fibrosis in the parents, the prognosis is favorable. Fetal karyotyping is recommended when additional structural anomalies are present.
Asunto(s)
Calcinosis/diagnóstico por imagen , Resultado del Embarazo , Ultrasonografía Prenatal , Aneuploidia , Calcinosis/embriología , Fibrosis Quística/diagnóstico , Fibrosis Quística/genética , Femenino , Enfermedades Fetales/diagnóstico , Humanos , Recién Nacido , Infecciones/diagnóstico , Infecciones/embriología , Hepatopatías/diagnóstico por imagen , Hepatopatías/embriología , Enfermedades Peritoneales/diagnóstico por imagen , Enfermedades Peritoneales/embriología , Embarazo , Estudios RetrospectivosRESUMEN
A novel presentation of endometriosis is described in which the lesion is identified within the brim or floor of peritoneal pockets located within a crescentic band in the posterior pelvis. The predictability of these peritoneal pockets and their strong association with other anomalies of the Mullerian and urinary tracts raises the possibility of a congenital origin.