RESUMEN
As part of a health-hazard survey on the health risk of hospital cleaning workers from exposure to Lyorthol, a hazard assessment of o-benzo-p-chlorophenol, one of the constituents of Lyorthol, has been prepared. In this paper, the physical and chemical characteristics, kinetics and effects of o-benzochlorophenol are described and discussed, and an overall, summarizing hazard evaluation is presented.
Asunto(s)
Diclorofeno/análogos & derivados , Desinfectantes/toxicidad , Administración Oral , Adulto , Animales , Diclorofeno/administración & dosificación , Diclorofeno/efectos adversos , Diclorofeno/farmacocinética , Diclorofeno/toxicidad , Desinfectantes/administración & dosificación , Desinfectantes/efectos adversos , Desinfectantes/farmacocinética , Femenino , Servicio de Limpieza en Hospital , Humanos , Masculino , Persona de Mediana Edad , Pruebas de Mutagenicidad , Exposición Profesional , Personal de Hospital , Conejos , Ratas , Reproducción/efectos de los fármacos , Piel/efectos de los fármacos , Distribución TisularRESUMEN
A case is described of a saturation diver with no previous history of asthma who repeatedly developed work-related symptoms of asthma at pressure, which appear to be causally related to the use of dichlorophen as a disinfectant agent. Although challenge tests were negative, suggesting that dichlorophen may have been acting as an irritant rather than as a sensitizer, the symptoms were abolished by the use of an alternative disinfectant agent. The potential importance of this effect in a diver is discussed, and the case highlights the importance of the use of nontoxic agents in the diving environment.