RESUMEN
Purpose To evaluate the effect of a PP mesh on duct deferens morphology, testicular size and testosterone levels. Methods Forty adult male rats were distributed into groups: 1) no surgery; 2) inguinotomy; 3) mesh placed on the duct deferens; and 4) mesh placed on the spermatic funiculus. After 90 postoperative days, the inguinal region was resected, and blood samples were collected for the measurement of serum testosterone (pg/dl). The ducts deferens were sectioned in three axial sections according to the relationship with the mesh cranial, medial and caudal. The wall thickness and duct deferens lumen area were measured. Results The morphology of the duct deferens was preserved in all groups. The mesh placement did not alter this morphology in any of the analyzed segments. Surgery, with or without mesh placement, did not alter the morphology, wall thickness or lumen area (p>0.05). In all operated groups, serum testosterone levels were similar (p>0.05) but there was a decrease in testicle size (p 0.05). Conclusion Surgery, with or without mesh placement, did not alter the morphology of the duct deferens and, although this treatment resulted in testicular size reduction, it did not affect serum testosterone levels.(AU)
Asunto(s)
Animales , Masculino , Ratas , Polipropilenos/efectos adversos , Conducto Deferente/crecimiento & desarrollo , Testículo/crecimiento & desarrollo , Mallas Quirúrgicas/efectos adversos , Mallas Quirúrgicas/veterinaria , Testosterona/análisis , Hormonas Esteroides Gonadales/análisisRESUMEN
A pesquisa teve como objetivo comparar a eficiência da abraçadeira de náilon e do fio de náilon na deferentectomia e na laqueação dos ductus deferentes em cães adultos. A comparação incluiu as manobras cirúrgicas, o tempo de cirurgia e tempo decorrido à azoospermia. Foram utilizados doze cães machos, com idade entre um a oito anos, de raça variada pesando entre 11 a 26 kg. Foram divididos em quatro grupos de três animais, Grupo 1 foi submetido à deferentectomia usando a abraçadeira de náilon para ligadura dos ductus deferentes, Grupo 2 foi submetido à laqueação dos ductus deferentes usando a abraçadeira de náilon, Grupo 3 foi submetido à deferentectomia usando o fio de náilon, Grupo 4 foi submetido à laqueação dos ductus deferentes usando o fio de náilon. Constatou-se que a abraçadeira de náilon foi de fácil manipulação o que reduziu o tempo cirúrgico e consequentemente o tempo de anestesia e os custos que envolvem todo o processo. A azoospermia ocorreu na primeira semana após a cirurgia em todos os grupos de estudo.
The aim of the study was to compare the effectiveness of the nylon clamp and wire in deferentectomy and ligation of the deferens ducts in adult dogs. The comparison included surgery techniques, surgery time and azoospermy time. We used twelve male dogs, aged between one and eight years old, and weighing between eleven and twenty six kilograms. The animals were divided in four groups of three animals, Group 1, deferentectomy was performed using nylon clamp; Group 2, ligation of the deferens ducts using nylon clamp; Group 3, deferentectomy using nylon wire, Group 4, ligation of deferens ducts using nylon wire. The nylon clamp was easy to manipulate, which reduced surgical time and consequently the anesthesia time and the costs involved throughout the process. Azoospermy occurred in the first week after the surgery in all study groups.
Asunto(s)
Animales , Perros , Conducto Deferente/anomalías , Conducto Deferente/crecimiento & desarrollo , Vasectomía/tendencias , Vasectomía/veterinariaRESUMEN
A pesquisa teve como objetivo comparar a eficiência da abraçadeira de náilon e do fio de náilon na deferentectomia e na laqueação dos ductus deferentes em cães adultos. A comparação incluiu as manobras cirúrgicas, o tempo de cirurgia e tempo decorrido à azoospermia. Foram utilizados doze cães machos, com idade entre um a oito anos, de raça variada pesando entre 11 a 26 kg. Foram divididos em quatro grupos de três animais, Grupo 1 foi submetido à deferentectomia usando a abraçadeira de náilon para ligadura dos ductus deferentes, Grupo 2 foi submetido à laqueação dos ductus deferentes usando a abraçadeira de náilon, Grupo 3 foi submetido à deferentectomia usando o fio de náilon, Grupo 4 foi submetido à laqueação dos ductus deferentes usando o fio de náilon. Constatou-se que a abraçadeira de náilon foi de fácil manipulação o que reduziu o tempo cirúrgico e consequentemente o tempo de anestesia e os custos que envolvem todo o processo. A azoospermia ocorreu na primeira semana após a cirurgia em todos os grupos de estudo.(AU)
The aim of the study was to compare the effectiveness of the nylon clamp and wire in deferentectomy and ligation of the deferens ducts in adult dogs. The comparison included surgery techniques, surgery time and azoospermy time. We used twelve male dogs, aged between one and eight years old, and weighing between eleven and twenty six kilograms. The animals were divided in four groups of three animals, Group 1, deferentectomy was performed using nylon clamp; Group 2, ligation of the deferens ducts using nylon clamp; Group 3, deferentectomy using nylon wire, Group 4, ligation of deferens ducts using nylon wire. The nylon clamp was easy to manipulate, which reduced surgical time and consequently the anesthesia time and the costs involved throughout the process. Azoospermy occurred in the first week after the surgery in all study groups.(AU)
Asunto(s)
Animales , Perros , Conducto Deferente/anomalías , Conducto Deferente/crecimiento & desarrollo , Vasectomía/tendencias , Vasectomía/veterinariaRESUMEN
The effects of maternal exposure to fenvalerate during the prenatal and postnatal periods of sexual brain differentiation were studied in adult male offspring. Behavioral (open field, stereotyped, and sexual behaviors), physical (sexual maturation, body and organ weights), endocrine (testosterone levels), and neurochemical (striatal and hypothalamic monoamine and respective metabolite levels) data were assessed. The results showed that there was no change in the age of testis descent or testis weight, nor were there changes in monoamine levels or stereotyped behavior. However, there were significant reductions in ductus deferens and seminal vesicle weights and plasma testosterone concentrations. In addition, treated offspring showed decreased male sexual behavior and increased immobility in the open field. These results indicate that perinatal exposure to fenvalerate during the critical periods of male brain sexual differentiation has long-term effects on the reproductive physiology and behavior of male rats.
Asunto(s)
Insecticidas/efectos adversos , Efectos Tardíos de la Exposición Prenatal , Piretrinas/efectos adversos , Animales , Conducta Animal/efectos de los fármacos , Monoaminas Biogénicas/metabolismo , Peso Corporal/efectos de los fármacos , Cuerpo Estriado/efectos de los fármacos , Cuerpo Estriado/metabolismo , Sistema Endocrino/efectos de los fármacos , Femenino , Hipotálamo/efectos de los fármacos , Hipotálamo/metabolismo , Locomoción/efectos de los fármacos , Masculino , Nitrilos , Tamaño de los Órganos/efectos de los fármacos , Embarazo , Próstata/crecimiento & desarrollo , Ratas , Ratas Wistar , Vesículas Seminales/crecimiento & desarrollo , Caracteres Sexuales , Conducta Sexual Animal/efectos de los fármacos , Testosterona/sangre , Conducto Deferente/crecimiento & desarrolloRESUMEN
Algumas características morfológias do desenvolvimento pós-natal do ducto deferente no hamster dourado, em diferentes idades, säo descritas. Observou-se que embora a morfologia do epitélio deferencial no hamster tenha diferenciaçäo precoce, já sendo observada aos 10 dias de idade, este epitélio mostra um decréscimo de altura celular entre 10 e 60 dias. Contudo, a túnica mucosa, como um todo, näo apresenta um padräo similar ao do epitélio na diferenciaçäo pós-natal. Há uma ligeira variabilidade na composiçäo e quantidade do tecido conjuntivo da lâmina própria, o que provavelmente explicaria a observaçäo no nível da túnica mucosa, durante o desenvolvimento pós-natal. A túnica muscular, a camada mais espessa da parede tubular deferencial, apresentou em forma geral um aumento progressivo entre a idade juvenil de 10 dias e a idade pós-puberal de 60 dias.