Asunto(s)
Ovario/irrigación sanguínea , Complicaciones Cardiovasculares del Embarazo/cirugía , Útero/irrigación sanguínea , Enfermedades Vasculares/cirugía , Adulto , Femenino , Hemoperitoneo/etiología , Hemoperitoneo/cirugía , Humanos , Embarazo , Complicaciones Cardiovasculares del Embarazo/complicaciones , Rotura Espontánea , Enfermedades Vasculares/complicaciones , VenasRESUMEN
Children born to women participating in a prospective study of hypertension during pregnancy were followed up from birth. Data on growth and development at the age of 71/2 years of 56 children whose mothers had superimposed pre-eclampsia are compared with results of 176 children whose mothers had only hypertension. Perinatal mortality in the hypertension-only group was similar to that for the hospital population in general at the time of their birth; but in the group who developed preeclampsia it was significantly higher. At the age of 71/2 years no differences were found in the frequency of health, handicap, sight and hearing problems, weight, height, head circumference, and standing and supine blood pressures. For six aspects of intellectual development children in the pre-eclampsia group had slightly higher mean scores; and in one of these, "perceptual matching' the difference was significant after adjustment had been made for confounding variables. Pre-eclampsia superimposed on hypertension does not increase the likelihood of impaired growth and development among children who survive the perinatal period.
Asunto(s)
Discapacidades del Desarrollo/etiología , Trastornos del Crecimiento/etiología , Hipertensión/complicaciones , Preeclampsia/complicaciones , Complicaciones Cardiovasculares del Embarazo/complicaciones , Efectos Tardíos de la Exposición Prenatal , Niño , Femenino , Muerte Fetal/etiología , Humanos , Inteligencia , Masculino , Embarazo , Proteinuria/complicacionesAsunto(s)
Placenta , Diagnóstico Prenatal , Síndrome de Dificultad Respiratoria del Recién Nacido/diagnóstico , Ultrasonografía , Cesárea , Femenino , Monitoreo Fetal , Humanos , Hipertensión/complicaciones , Recién Nacido , Masculino , Placenta/fisiología , Embarazo , Complicaciones Cardiovasculares del Embarazo/complicaciones , Probabilidad , Respiración Artificial , Síndrome de Dificultad Respiratoria del Recién Nacido/mortalidad , Síndrome de Dificultad Respiratoria del Recién Nacido/terapiaAsunto(s)
Aorta Torácica/anomalías , Coartación Aórtica/complicaciones , Complicaciones Cardiovasculares del Embarazo , Adulto , Aorta Torácica/diagnóstico por imagen , Coartación Aórtica/diagnóstico por imagen , Femenino , Humanos , Hipertensión/complicaciones , Recién Nacido , Embarazo , Complicaciones Cardiovasculares del Embarazo/complicaciones , RadiografíaRESUMEN
The birth of a child with a reduction limb defect (RLD) was evaluated in relation to vaginal bleeding, threatened abortion, and other complications of pregnancy, placental weight, birth weight, family history, parental age, and the outcome of previous pregnancies. The material consisted of 453 cases of reduction limb defect and an equal number of non-malformed controls matched for time and place. The children were born in Finland during 1964-77. The cases with reduction limb defect without additional malformations were analysed separately. Statistically significant associations were found between the occurrence of reduction limb defect and the following risk indicators: vaginal bleeding, threatened abortion, duration of gestation under 37 weeks, placental weight 400 g or less, birth weight 2500 g or less, and any type of malformation in the relatives. Vaginal bleeding indicated the risk of reduction limb defect to be increased about fourfold; short gestation indicated about twofold risk of reduction limb defect as an isolated malformation. Both low placental weight and low birth weight were associated to a threefold risk of an isolated reduction limb defect. These factors of an abnormal pregnancy indicated even higher risk of reduction limb defect with additional malformations. Preliminary genetic analysis suggests that hereditary factors play no major part in the aetiology of reduction limb defects.
Asunto(s)
Deformidades Congénitas de las Extremidades , Amenaza de Aborto/complicaciones , Peso al Nacer , Anomalías Congénitas/genética , Femenino , Edad Gestacional , Humanos , Recién Nacido , Recien Nacido Prematuro , Tamaño de los Órganos , Linaje , Placenta/anatomía & histología , Embarazo , Complicaciones Cardiovasculares del Embarazo/complicaciones , Riesgo , Hemorragia Uterina/complicacionesRESUMEN
Routine investigations designed to detect excessive intravascular coagulation in patients with gestational hypertension and pre-eclampsia have been analysed in 936 cases. Reticulocyte counts did not differ significantly from those in normal controls and abnormal red cell morphology was detected in only two patients. Fibrinogen degradation products and thrombocytopenia were found in about 10% of all hypertensive women and macrothrombocytosis in 32%. Neither reticulocyte counts nor the scanning of stained blood films for evidence of microangiopathic haemolysis have a place in the routine investigation of pre-eclampsia and it is doubtful whether any of the other screening tests can influence the management of patients with uncomplicated gestational hypertension. In fully developed pre-eclampsia, macrothrombocytosis is found in about 50% of patients, fibrinogen degradation products and thrombocytopenia in about 15%. All three parameters reflect the degree of clinical severity of the disease.
Asunto(s)
Coagulación Intravascular Diseminada/diagnóstico , Preeclampsia/sangre , Complicaciones Cardiovasculares del Embarazo/sangre , Pruebas de Coagulación Sanguínea , Coagulación Intravascular Diseminada/complicaciones , Recuento de Eritrocitos , Femenino , Productos de Degradación de Fibrina-Fibrinógeno/análisis , Hemoglobinometría , Humanos , Recuento de Plaquetas , Preeclampsia/complicaciones , Embarazo , Complicaciones Cardiovasculares del Embarazo/complicaciones , ReticulocitosAsunto(s)
Traumatismos del Nacimiento/complicaciones , Eritroblastosis Fetal/etiología , Muerte Fetal/etiología , Enfermedades Fetales/etiología , Complicaciones del Embarazo , Incompatibilidad de Grupos Sanguíneos/complicaciones , Eritroblastosis Fetal/terapia , Recambio Total de Sangre , Femenino , Humanos , Hipertensión/complicaciones , Recién Nacido , Embarazo , Complicaciones Cardiovasculares del Embarazo/complicaciones , Complicaciones Hematológicas del Embarazo/complicaciones , Complicaciones Infecciosas del Embarazo/complicaciones , Embarazo en Diabéticas/complicaciones , Sistema del Grupo Sanguíneo Rh-Hr , Trastornos Relacionados con Sustancias/complicaciones , Enfermedades de la Tiroides/complicacionesAsunto(s)
Muerte Fetal/etiología , Hipertensión/complicaciones , Mortalidad Infantil , Complicaciones Cardiovasculares del Embarazo/complicaciones , Proteinuria/complicaciones , Desprendimiento Prematuro de la Placenta/mortalidad , Femenino , Retardo del Crecimiento Fetal/mortalidad , Humanos , Hipertensión/mortalidad , Recién Nacido , Infarto/mortalidad , Enfermedades Placentarias/complicaciones , Enfermedades Placentarias/mortalidad , Embarazo , Complicaciones Cardiovasculares del Embarazo/mortalidad , Estudios Prospectivos , Proteinuria/mortalidadAsunto(s)
Retardo del Crecimiento Fetal/etiología , Complicaciones del Embarazo , Volumen Cardíaco , Femenino , Retardo del Crecimiento Fetal/fisiopatología , Cardiopatías Congénitas/complicaciones , Hemoglobinopatías/complicaciones , Humanos , Hipertensión/complicaciones , Enfermedades Placentarias/complicaciones , Placenta Previa/complicaciones , Preeclampsia/complicaciones , Embarazo , Complicaciones del Embarazo/fisiopatología , Complicaciones Cardiovasculares del Embarazo/complicaciones , Complicaciones Hematológicas del Embarazo/complicacionesAsunto(s)
Ovario/irrigación sanguínea , Complicaciones Cardiovasculares del Embarazo/complicaciones , Útero/irrigación sanguínea , Várices/complicaciones , Adulto , Femenino , Hemorragia/etiología , Humanos , Enfermedades del Ovario/etiología , Embarazo , Embarazo Múltiple , Rotura Espontánea , Síndrome , Hemorragia Uterina/etiologíaRESUMEN
Our resent experience on six cases of aplastic anemia complicated with pregnancy is described. In addition, 43 similar cases were collected from the literature and reviewed to analyze some prognostic aspects of this relatively rare but potentially serious complication. Clinical and hematological data were treated to extract some clinically meaningful factors in relation to the success and failure of pregnancy. Among initial hematological parameters, no significant difference was found between successful and unsuccessful cases with an exception of hemoglobin concentration. The patients diagnosed as aplastic anemia prior to conception demonstrated an better outcome of pregnancy as well as survival rate of mother when compared with those diagnosed during pregnancy. Mortality has apparently improved after the late 1950's. Success rate of pregnancy before 1958 was 21%, while it was 67% and 71% in the era of 1959-1969 and after 1970, respectively. However, hemorrhage and infection remained to be two major causes of maternal death in both eras. Based on these observations, the currently recommendable attitude to this complication is discussed.
Asunto(s)
Anemia Aplásica/diagnóstico , Complicaciones Hematológicas del Embarazo/diagnóstico , Adulto , Infecciones Bacterianas/complicaciones , Femenino , Hemoglobinas/análisis , Hemorragia/complicaciones , Humanos , Embarazo , Complicaciones Cardiovasculares del Embarazo/complicaciones , Complicaciones Hematológicas del Embarazo/complicaciones , Complicaciones Infecciosas del Embarazo/complicaciones , Pronóstico , Factores de TiempoAsunto(s)
Hipertensión/sangre , Complicaciones Cardiovasculares del Embarazo/sangre , Adulto , Coagulación Sanguínea , Volumen Sanguíneo , Coagulación Intravascular Diseminada/complicaciones , Eclampsia/sangre , Eclampsia/complicaciones , Femenino , Productos de Degradación de Fibrina-Fibrinógeno/análisis , Fibrinógeno/análisis , Hemólisis , Humanos , Hipertensión/complicaciones , Hipertensión/fisiopatología , Preeclampsia/sangre , Preeclampsia/complicaciones , Embarazo , Complicaciones Cardiovasculares del Embarazo/complicaciones , Complicaciones Cardiovasculares del Embarazo/fisiopatología , Trombocitopenia/complicacionesAsunto(s)
Eclampsia/complicaciones , Adulto , Anciano , Enfermedad Crónica , Diabetes Mellitus/etiología , Femenino , Estudios de Seguimiento , Humanos , Hipertensión/etiología , Persona de Mediana Edad , Mortalidad , Paridad , Embarazo , Complicaciones Cardiovasculares del Embarazo/complicaciones , Pronóstico , RecurrenciaAsunto(s)
Coagulación Intravascular Diseminada/etiología , Complicaciones Cardiovasculares del Embarazo/complicaciones , Hemorragia Uterina/complicaciones , Desprendimiento Prematuro de la Placenta/complicaciones , Embolia de Líquido Amniótico/complicaciones , Femenino , Muerte Fetal/complicaciones , Humanos , Hemorragia Posparto/complicaciones , Preeclampsia/complicaciones , Embarazo , Sepsis/complicacionesAsunto(s)
Hipertensión/patología , Placenta/patología , Complicaciones Cardiovasculares del Embarazo/patología , Útero/patología , Arterias/patología , Decidua/patología , Femenino , Humanos , Hipertensión/complicaciones , Hipertensión/terapia , Hipertensión Renal/complicaciones , Placenta/irrigación sanguínea , Placentación , Preeclampsia/complicaciones , Preeclampsia/patología , Embarazo , Complicaciones Cardiovasculares del Embarazo/complicaciones , Complicaciones Cardiovasculares del Embarazo/terapia , Trofoblastos/patología , Enfermedades Vasculares/etiología , Enfermedades Vasculares/patologíaRESUMEN
Blood samples were taken from 254 women with pregnancies with various complications and 119 completely normal pregnant women for measurement of serum human placental lactogen (hPL) during the third trimester. The value of this test in the management of these pregnancies was retrospectively evaluated through details of outcome. Serum hPL and urinary estriol were compared as tools for assessment of fetal condition. Serum hPL was found to be very efficient in the prenatal diagnosis of intrauterine growth retardation associated with maternal hypertension. Low hPL levels were recorded in all severely hypertensive patients who were delivered of small-for-dates infants (a 100 per cent prediction rate), while 30 per cent of these patients had normal estriol values. Prediction rate of postmature infants by serum hPL level was 70 per cent as compared to 50 per cent by urinary estriol level. The diagnostic significance of low hPL levels is emphasized, with stress upon its value in early detection of unfavorable intrauterine environment. The importance of preterm deliveries in pregnancies involving intrauterine growth retardation and low hPL levels is discussed and demonstration cases are presented.
Asunto(s)
Lactógeno Placentario/sangre , Complicaciones del Embarazo/sangre , Adulto , Estriol/orina , Femenino , Retardo del Crecimiento Fetal/diagnóstico , Humanos , Hipertensión/complicaciones , Recién Nacido , Recién Nacido Pequeño para la Edad Gestacional , Enfermedades Placentarias/diagnóstico , Pruebas de Función Placentaria , Embarazo , Complicaciones Cardiovasculares del Embarazo/complicaciones , Tercer Trimestre del Embarazo , Embarazo Prolongado , Diagnóstico Prenatal , Riesgo , SíndromeRESUMEN
Primary hyperparathyroidism of pregnancy may result in spontaneous abortion, neonatal hypocalcemia, or neonatal tetany if appropriate treatment is not instituted. Of great importance in prevention of these complications is an awareness by physicians that this disease exists and is of clinical importance. Parathyroidectomy performed during the second trimester of pregnancy offers the best chance for fetal and neonatal survival. This operation results in little risk to either the mother or the fetus. Normal calcium homeostasis is restored to the fetus and the risk of hypocalcemia in the neonatal period is virtually eliminated.
Asunto(s)
Hiperparatiroidismo/cirugía , Glándulas Paratiroides/cirugía , Complicaciones del Embarazo/cirugía , Adulto , Femenino , Humanos , Hipertensión/complicaciones , Recién Nacido , Glándulas Paratiroides/anomalías , Paridad , Embarazo , Complicaciones Cardiovasculares del Embarazo/complicaciones , Segundo Trimestre del EmbarazoRESUMEN
Great advances in ultrasound instrumentation have enabled the physician to delineate subtle intrauterine changes. Not only can specific measurements of the fetal body be obtained but tissue textures within fetal organs can be appreciated. The perinatologist is constantly searching for ways to learn more about the fetus, and ultrasound has clearly become a major implement in this search. The following discussion will focus on information made available by ultrasound for aid in the modern management of hypertension, one of the most challenging conditions complicating pregnancy.