RESUMEN
Nowadays, alternative methods that do not use formaldehyde to preserve cadavers must be used due to this substance's toxicity. Synthetic models are a training option for teaching, but cost makes their use unviable in most underdeveloped countries. The present study's main objective was to develop a model for education and researching thorax radiology in cadavers of chemically prepared dogs. Megaesophagus, pleural effusion, pneumothorax, and bronchography, as well as pulmonary insufflation, were simulated in 32 dogs cadavers, which received 150 mL/kg of pure ethyl alcohol solution with 5% glycerin followed by injection of 120 mL/kg of a solution containing 20% sodium chloride, 1% sodium nitrite and 1% sodium nitrate; they were kept refrigerated between 2 to 6 °C, for 30, 60, 90 or 120 days (G30, G60, G90, G120). There was no contamination, putrid odor, or subcutaneous emphysema. The pulmonary insufflation was kept, and the color and the consistency were similar to a fresh corpse after 120 days of conservation. It was possible to perform radiographic procedures, and almost all affections could be greatly mimicked. Megaesophagus and bronchography were easily simulated. Pneumothorax was the most challenging condition to be reproduced, especially in cadavers with some liquid in the thorax. The alcoholic and curing salt solutions are an embalming alternative with low financial and environmental costs and proved to preserve corpses.
Nos dias atuais, métodos alternativos e que não utilizem o formaldeído para conservação de cadáveres devem ser empregados, devido à toxicidade desse agente. Modelos sintéticos são opção de treinamento para o ensino, mas geralmente o preço inviabiliza seu uso na maioria dos países subdesenvolvidos. O objetivo do presente trabalho foi desenvolver um modelo visando ao ensino e pesquisa da radiologia torácica em cadáveres de cães quimicamente preparados. Foram simulados megaesôfago, efusão pleural, pneumotórax e broncografia, além de insuflação pulmonar, em 32 cadáveres de cães, que receberam 150 mL/kg de solução de álcool etílico puro com 5% de glicerina seguido de injeção de 120 mL/kg de solução contendo 20% de cloreto de sódio, 1% de nitrito de sódio e 1% de nitrato de sódio, mantidos sob refrigeração entre 2 e 6 graus, por 30, 60, 90 ou 120 dias (G30, G60, G90, G120). Não houve contaminação, odor pútrido ou enfisema subcutâneo. A insuflação pulmonar foi mantida, e a cor e a consistência foram semelhantes a um cadáver fresco após 120 dias de conservação. Em todos os grupos foi possível realizar os procedimentos radiográficos e quase todas afecções puderam ser grandemente mimetizadas. O megaesôfago e a broncografia foram facilmente simuladas. O pneumotórax foi a afecção mais difícil de ser simulada principalmente nos cadáveres com um pouco de líquido na cavidade torácica. A solução alcoólica e de sal de cura são uma alternativa de embalsamamento com baixo custo financeiro e ambiental e comprovadamente conservam cadáveres.
Asunto(s)
Animales , Perros , Radiología , Embalsamiento , Caja TorácicaRESUMEN
OBJECTIVE: To assess the rib cage expansion and respiratory rate in newborns using an abdominal stabilization band. METHODS: The study included 32 newborns of both genders, with gestational age between 35 and 41 weeks. The abdominal stabilization band was used for 15 minutes between the xiphoid process and the anterosuperior iliac crest, with an abdominal contention 0.5cm smaller than the abdominal circumference. The rib cage expansion was evaluated by a breathing transducer (Pneumotrace II™) three minutes before using the band, during the use (15 minutes), and ten minutes after removing the band. The Shapiro-Wilk test verified data normality, and the Wilcoxon test compared the variables considering rib cage expansion and respiratory rate. Significance was set to p<0.05. RESULTS: There was an increase in respiratory rate when comparing before and ten minutes after removing (p=0.008) the abdominal stabilization band, as well as when comparing during its use and ten minutes after its removal (p=0.001). There was also an increase in rib cage expansion when comparing before and during the use of the abdominal stabilization band (p=0.005). CONCLUSIONS: The use of the abdominal stabilization band promoted an increase in the rib cage expansion and respiratory rate in the assessed newborns and may be a viable option to improve the respiratory kinematics of this population.
Asunto(s)
Abdomen , Mecánica Respiratoria , Humanos , Recién Nacido , Femenino , Masculino , Lactante , Mecánica Respiratoria/fisiología , Abdomen/cirugía , Abdomen/fisiología , Músculos Abdominales , Respiración , Caja TorácicaRESUMEN
INTRODUCTION: Tuberculosis (TB) is an infectious, transmissible and immune disease caused by the Mycobacterium tuberculosis-complex (MTBC). Although osteoarticular tuberculosis (OATB) has been widely described, the ribcage variety remains a rare form. CASE REPORT: A thirteen-month-old male and a twenty-month-old female, both with pain and increased volume of anterolateral left rib cage were described. Physical examination revealed the presence of a soft consistent mass at the level of the 9th and 5th costal arches in the male and female patients respectively. Upon clinical evaluation, tuberculosis was suspected, which was confirmed by X-ray and histopathological studies. After confirmation, the management, based on anti-tuberculosis therapy was started as follows: nine months of anti-tuberculosis therapy for the male patient and fourteen months for the female. The outcomes were favorable for both patients. However, further interventions, consisting of abscess drainage in the male patient and excisional biopsy in the female patient were necessary. With these therapeutic interventions, to date, the patients are without any evidence of active TB.
Asunto(s)
Mycobacterium tuberculosis , Tuberculosis , Antituberculosos/uso terapéutico , Drenaje , Femenino , Humanos , Lactante , Masculino , Caja Torácica , Tuberculosis/tratamiento farmacológicoRESUMEN
Defective management of secretions is one of the most frequent complications in invasive mechanically ventilated patients. Clearance of secretions through chest physiotherapy is a critical aspect of the treatment of these patients. Manual rib cage compression is one of the most practiced chest physiotherapy techniques in ventilated patients; however, its impact on clinical outcomes remains controversial due to methodological issues and poor understanding of its action. In this review, we present a detailed analysis of the physical principles involved in rib cage compression technique performance, as well as the physiological effects observed in experimental and clinical studies, which show that the use of brief and vigorous rib cage compression, based on increased expiratory flows (expiratory-inspiratory airflow difference of > 33L/minute), can improve mucus movement toward the glottis. On the other hand, the use of soft and gradual rib cage compression throughout the whole expiratory phase does not impact the expiratory flows, resulting in ineffective or undesired effects in some cases. More physiological studies are needed to understand the principles of the rib cage compression technique in ventilated humans. However, according to the evidence, rib cage compression has more potential benefits than risks, so its implementation should be promoted.
O manejo deficiente das secreções é uma das complicações mais frequentes em pacientes em ventilação mecânica invasiva. A depuração das secreções por meio da fisioterapia respiratória é um aspecto crítico do tratamento desses pacientes. A compressão torácica manual é uma das técnicas de fisioterapia respiratória mais praticadas em pacientes ventilados, mas seu impacto nos desfechos clínicos permanece controverso devido a questões metodológicas e ao pouco conhecimento sobre sua ação. Nesta revisão, apresenta-se uma análise detalhada dos princípios físicos envolvidos na execução da técnica de compressão torácica. Também investigam-se os efeitos fisiológicos observados em estudos experimentais e clínicos, que mostram que o uso de compressão torácica curta e vigorosa, baseada no aumento de fluxos expiratórios (diferença de fluxo aéreo inspiratório-expiratório > 33L/minuto), pode melhorar o movimento do muco em direção à glote. Por outro lado, o uso de compressão torácica suave e gradual ao longo de toda a fase expiratória não afeta os fluxos expiratórios, resultando em efeitos ineficazes ou indesejados em alguns casos. Mais estudos fisiológicos são necessários para entender os princípios da técnica de compressão torácica em pacientes ventilados. No entanto, de acordo com as evidências, a compressão torácica tem mais benefícios potenciais do que riscos, o que incentiva sua implementação.
Asunto(s)
Ventilación Pulmonar , Respiración Artificial , Espiración , Humanos , Presión , Ventilación Pulmonar/fisiología , Respiración Artificial/métodos , Caja TorácicaRESUMEN
Chest compression is a parameter of injury criteria assessment for human beings. Additionally, it is used to find the external compression response as a result of vehicle crashes, falls, or sporting impacts. This behavioral feature is described by many deterministic models related to specific experimental tests, hindering distinct scenarios. The present study evaluates the energy absorbed as a function of rib compression. The proposed model was obtained from three different computed tomography (CT) studies. The anthropometric values are interpolated to obtain a parametric curve for a human rib's average size. The computed results are compared against an STL-DICOM® file used to obtain a virtual reconstruction of one rib. A numerical model of the behavior of the thorax displacement expressed injury in the human rib model's stiffness. The proposed model is used to determine the correlation of the input payload versus the numerical stiffness value. The outcome is confirmed by numerical analyses applied to a virtual human rib reconstruction.
Asunto(s)
Reanimación Cardiopulmonar , Traumatismos Torácicos , Humanos , Caja Torácica , Tórax/diagnóstico por imagen , Tórax/fisiología , Tomografía Computarizada por Rayos XRESUMEN
Pneumonia is responsible for high mortality rates around the world, and its major treatment is based on antibiotic treatment. Antimicrobial resistance has been increasing in the last years, resulting in relevant public health concern. A promising alternative for pneumonia is antimicrobial photodynamic therapy. The purpose of this study was to investigate whether 808 nm wavelength is able to be transmitted through the biological tissues of the thoracic wall and be delivered in enough energy inside the cage to activate indocyanine green and promote photodynamic response. A light source panel was developed composed of 200 lasers centered at 808 nm with an irradiance of 77.8 ± 10.0 mW/cm2 and tested in an ex vivo thoracic cage model. Monte Carlo simulations were used to understand the photon migration through all the tissues at the thoracic wall. It was observed that tissues responsible for the major absorption of photons are the skin and subcutaneous fat. Experimental measurement of the irradiance was obtained after the light pass-through ex vivo pig thoracic cage, obtaining 3% to 5% of the emitted irradiance. Finally, it was observed that even with 3% of the initial irradiance, a 99.9% reduction of the Streptococcus pneumoniae was successfully achieved after 42.6 minutes of irradiation.
Asunto(s)
Iluminación , Fotoquimioterapia , Animales , Método de Montecarlo , Fotoquimioterapia/métodos , Caja Torácica , Streptococcus pneumoniae , PorcinosRESUMEN
Introducción. La enfermedad de Erdheim Chester es un trastorno infrecuente, de etiología no clara y edad de presentación variable, que se caracteriza por la proliferación anormal de histiocitos no Langerhans. Puede presentarse de forma asintomática, con manifestaciones locales o como complicaciones sistémicas. El diagnóstico se basa en las condiciones clínicas del paciente, estudios imagenológicos y el estudio anatomopatológico, mediante el cual se confirma la enfermedad. Caso clínico. Paciente masculino con una lesión lítica en el séptimo arco costal, inicialmente asintomático y posteriormente con dolor torácico persistente. Se realizó resección y reconstrucción de la pared torácica, con resolución de la sintomatología y adecuada evolución posoperatoria. El resultado de la patología confirmó el diagnóstico de enfermedad de Erdheim Chester. Discusión. Se presenta el caso de un paciente con compromiso costal y fractura patológica como localización y manifestación inusual de la enfermedad de Erdheim Chester, tratado quirúrgicamente de forma adecuada, y sin aparición de recidiva. Debido a la diversidad de síntomas que pueden presentar y a la afectación de múltiples órganos, además de los estudios imagenológicos, la clínica debe orientar los exámenes complementarios, como electro o ecocardiograma, resonancia nuclear magnética, o angioTAC. En los pacientes asintomáticos se ha recomendado un manejo expectante y en los sintomáticos el tratamiento médico con glucocorticoides, inhibidores de BRAF e interferón alfa. El papel de la cirugía no ha sido estudiado a profundidad
Introduction. Erdheim Chester disease is a rare disorder of unclear etiology and variable age of presentation, characterized by abnormal proliferation of non-Langerhans histiocytes. It can present asymptomatic, with local manifestations or as systemic complications. The diagnosis is based on the clinical conditions of the patient, imaging studies, and the pathological study, through which the disease is confirmed.Clinical case. A male patient with a lytic lesion in the seventh costal arch, initially asymptomatic and later with persistent chest pain, underwent resection and reconstruction of the chest wall, with resolution of the symptoms and adequate postoperative evolution. The pathology report confirmed the diagnosis of Erdheim Chester's disease.Discussion. The case of a patient with rib involvement and pathological fracture is presented as an unusual location and manifestation of Erdheim Chester's disease, treated surgically appropriately, and without recurrence. Due to the diversity of symptoms that they can present and the involvement of multiple organs, in addition to imaging studies, the clinic should direct complementary tests such as electrocardiogram or echocardiogram, magnetic resonance imaging, or CT angiography. Expectant management has been recommended in asymptomatic patients, and medical treatment with glucocorticoids, BRAF inhibitors, and interferon alfa in symptomatic patients. The role of surgery has not been studied in depth
Asunto(s)
Humanos , Enfermedad de Erdheim-Chester , Fracturas Espontáneas , Terapéutica , Huesos , Dolor en el Pecho , Caja TorácicaRESUMEN
RESUMEN Las fracturas costales son la lesión más frecuente en los traumatismos torácicos. La fijación de las fracturas ha estado dirigida clásicamente al volet costal. En los últimos años se han extendido las indi caciones a las fracturas múltiples desplazadas aun sin volet. Se consideran asimismo otras indicaciones de osteosíntesis menos frecuentes. La neumonía y contusión pulmonar graves que requieren asisten cia respiratoria mecánica son consideradas contraindicaciones para la fijación quirúrgica. La primera semana es el momento óptimo para su realización. Diversos dispositivos de fijación se han ideado; las placas de titanio son las más utilizadas. La osteosíntesis costal ofrece a los pacientes una recuperación más rápida con menor estadía hospitalaria y en cuidados críticos, así como mejor funcionalidad respi ratoria y menor dolor en el corto y largo plazo.
ABSTRACT Rib fractures are the most common injuries in chest trauma. Fracture fixation has been traditionally performed in flail chest patients. Over the past years, the indication has been extended to multiple, severely displaced non-flail pattern fractures. Other less common indications for osteosynthesis have also been considered. Severe pneumonia and lung contusion requiring mechanical ventilation are considered contraindication for surgical fixation. The optimal timing for the intervention is the first week. Several devices have been developed for fracture fixation; titanium plates are the most commonly used. Rib fixation offers patients a more rapid recovery with shorter length of hospital stay and of intensive care unit stay with improved respiratory function and pain management in the short and long term.
Asunto(s)
Fracturas de las Costillas/cirugía , Traumatismos Torácicos/cirugía , Fracturas de las Costillas/diagnóstico por imagen , Traumatismos Torácicos/terapia , Traumatismos Torácicos/diagnóstico por imagen , Caja Torácica/lesiones , Fijación Interna de FracturasRESUMEN
The vertebral heart size is a method used to measure the cardiac dimension in order to identify the remodeling of the chambres in heart disease. This study aims to determinate the vertebral heart size values at right lateral and ventrodorsal radiographs views relating to canines weight and body area variations. For the purpose of the study 40 healthy dogs within the age of 1 to 6 years, males and females, with deep or intermediated thorax were selected, brachycephalic dogs were not included in the study; the dogs were separated in four groups: group 1(n=9) compound of dogs up to 5 kg; group 2 (n=8) with dogs from 5,1 to 10 kg; group 3 (n=12) with dogs from 10,1 to19 kg and group 4 (n=11) with dogs weighing more than 19,1 kg. The values of body score, body mass index and the thorax configuration where previously measured, as well as the vertebral heart size and the depth width ratio from the radiographs. The results demonstrated intervals of right lateral-lateral vertebral heart size 9.9 to 10.4v and ventro-dorsal vertebral heart size of 9.8-10.3v. The study results show that the vertebral heart size numbers did not correlate with weight or body area, regardless the type of radiography view. Therefore, it can be concluded that the vertebral heart size in right lateral and ventrodorsal radiography can be used to rate the cardiac area, not suffering influence by the dog's weight or body area.
O vertebral heart size é um método utilizado para mensurar a dimensão cardíaca visando identificar os remodelamentos das câmaras nas cardiopatias. O objetivo do estudo foi determinar os valores de vertebral heart size nas projeções radiográficas latero-lateral direita e ventro-dorsal conforme as variações do peso e área corporal. Para isso, foram selecionados 40 cães hígidos com idade entre 1 e 6 anos, machos e fêmeas, com padrão torácico intermediário e profundo, com exclusão dos braquicefálicos; os cães foram divididos em quatro grupos: grupo 1 (n=9) composto por cães de até 5 kg; grupo 2 (n=8) com cães de 5,1 a 10 kg; grupo 3 (n=12) com cães de 10,1 a 19 kg e grupo 4 (n=11) com cães acima de 19,1 kg. Os valores de escore corporal, índice de massa corporal e conformação torácica foram previamente mensurados, bem como os valores dos vertebral heart size a relação profundidade/largura torácica das radiografias. Os resultados demonstraram intervalos de vertebral heart size latero-lateral 9.9 a 10.4v e vertebral heart size ventro dorsal de 9.8-10.3v. Os valores não apresentaram correlação com o peso e área corporal nos grupos estudados, independente das projeções estudas. Assim, pode-se concluir que método vertebral heart size nas projeções estudadas é aplicável na avaliação da área cardíaca, não sofrendo influências do peso e área corporal canina.
Asunto(s)
Animales , Perros , Peso Corporal/fisiología , Pesos y Medidas Corporales/veterinaria , Enfermedades Cardiovasculares/veterinaria , Perros/anatomía & histología , Variación Anatómica/fisiología , Corazón/anatomía & histología , Radiografía Torácica/veterinaria , Caja Torácica/anatomía & histología , Cardiopatías/veterinariaRESUMEN
Mulheres submetidas à cirurgia de mastectomia podem apresentar algumas complicações, dentre elas, alterações respiratórias e prejuízo funcional. O objetivo deste estudo foi avaliar a cinemática da parede torácica e a capacidade funcional no pós-operatório de pacientes mastectomizadas sem tratamento neoadjuvante e adjuvante associados. Foram avaliadas 4 mulheres no grupo mastectomia (GM) e 4 mulheres no grupo controle (GC). Todas as participantes foram submetidas aos procedimentos de avaliação antropométrica, função pulmonar, força muscular respiratória, cinemática da parede torácica e capacidade funcional. O GM também foi submetido à avaliação de inspeção e palpação torácica. Os dados foram analisados por meio de estatística descritiva. Foi observado que o GM apresentou menor variação de volume corrente da parede torácica, com delta de variação de 22,03% a menos que o GC, sendo a maior redução de volume corrente evidenciada no compartimento de caixa torácica pulmonar, com redução de 41,57% em relação ao GC. O GM não apresentou alterações de função pulmonar, força muscular respiratória e capacidade funcional, apresentando valores de normalidade nessas avaliações. Portanto, mulheres submetidas ao procedimento cirúrgico de mastectomia, sem tratamento neoadjuvante e adjuvante associados, não apresentaram comprometimento da função pulmonar, da força muscular respiratória e da capacidade funcional, contudo foi verificado redução do volume pulmonar na região do procedimento cirúrgico.
Women submitted to a mastectomy surgery may present some complications, among them, respiratory changes and functional impairment. The purpose of this study was to evaluate the chest wall kinematics and functional capacity in the postoperative period of mastectomized patients without associated adjuvant and neoadjuvant treatment. A total of four (4) women in the mastectomy group (MG) and four (4) in the control group (CG) were evaluated. All participants were submitted to the procedures of anthropometric evaluation, pulmonary function, respiratory muscle strength, chest wall kinematics and functional capacity. Patients in MG were also submitted to an inspection and palpation evaluation of the chest and breasts. Database was analyzed using descriptive statistics. It was observed that the MG presented a smaller variation of tidal volume of the chest wall, with a variation delta of 22.03% less than CG, with the largest reduction in tidal volume evidenced in the pulmonary chest cavity compartment, with a reduction of 41.57% when compared to CG. The MG did not present alterations of pulmonary function, respiratory muscle strength and functional capacity, presenting values of normality in these evaluations. Therefore, women submitted to the surgical procedure of mastectomy without associated neoadjuvant and adjuvant treatment did not present any impairment of pulmonary function, respiratory muscle strength and functional capacity. However, a reduction could be observed in the pulmonary volume in the region of the surgical procedure.
Asunto(s)
Humanos , Femenino , Persona de Mediana Edad , Anciano , Periodo Posoperatorio , Pruebas de Función Respiratoria , Mujeres/psicología , Capacidad Residual Funcional , Mastectomía/rehabilitación , Procedimientos Quirúrgicos Operativos/rehabilitación , Fenómenos Biomecánicos , Músculos Respiratorios/cirugía , Neoplasias de la Mama/cirugía , Volumen de Ventilación Pulmonar , Pared Torácica/cirugía , Fuerza Muscular , Caja Torácica/cirugíaRESUMEN
Objective: To assess thoraco-abdominal kinematics, respiratory muscle strength and electromyographic activity of the diaphragm (EAdi) in moderate-severe allergic rhinitis (AR) patients. Methods: A cross-sectional study involving 40 individuals (20 in the AR group) and 20 in the control group [CG]) was conducted. Ventilatory pattern and chest wall volume distribution (optoelectronic plethysmography), respiratory muscle strength (manovacuometry and sniff nasal inspiratory pressure [SNIP]), and EAdi were assessed in both groups. Results: The AR patients had impaired thoraco-abdominal kinematics (reduced total chest wall volume) (p = 0.004), lower values of total respiratory cycle time (p = 0.014) and expiratory time (p = 0.006). They also presented an increase of percentage contribution of the abdominal rib cage (p = 0.475) and respiratory rate (p = 0.019). A positive correlation among pulmonary rib cage tidal volume and MIP (r = 0.544; p < 0.001), SNIP (r = 0.615; p < 0.001), and MEP (r = 0.604; p < 0.001) was observed. After adjusting for age, BMI and gender through multivariate analysis, the individuals with AR presented lower values ââof MIP (ß = -24.341; p < 0.001), MEP (ß = -0.277; p < 0.001), SNIP (ß = -34.687; p < 0.001) and RMS (ß = -0.041; p = 0.017). Conclusions: The individuals with moderate-severe persistent AR had worse respiratory muscle strength, diaphragm activation and chest wall volume distribution with a higher abdominal contribution to tidal volume than the control group. These findings reinforce the notion that the upper and lower airways work in an integrated and synergistic manner.
Asunto(s)
Diafragma/fisiopatología , Músculos Intercostales/fisiopatología , Mecánica Respiratoria/fisiología , Rinitis Alérgica/fisiopatología , Pared Torácica/fisiopatología , Adulto , Fenómenos Biomecánicos , Estudios Transversales , Electromiografía , Femenino , Humanos , Masculino , Fuerza Muscular/fisiología , Pletismografía , Rinitis Alérgica/diagnóstico , Caja Torácica/fisiopatología , Índice de Severidad de la Enfermedad , Volumen de Ventilación Pulmonar/fisiologíaRESUMEN
Existem evidências de que alterações posturais possam influenciar no funcionamento da caixa torácica. Além disso, para uma respiração adequada, é necessária boa postura e equilíbrio muscular. O objetivo do presente estudo foi verificar se existe correlação entre a pressão plantar e a força muscular respiratória, visto que ambas sofrem interferência das alterações posturais. Foram avaliados 30 funcionários de uma instituição de Ensino Superior do Médio Paraíba, com idade média de 43,43 ± 13,29 anos, subdivididos em 2 grupos: Grupo experimental (I) e Grupo Controle (II). O grupo I foi submetido a 30 sessões de treinamento muscular respiratório; e ao final da intervenção, ambos os grupos foram reavaliados. Os resultados mostraram que algumas pressões plantares sofreram interferência significativa, com p < 0,05 da força muscular respiratória (PImáx e PEmáx), após o protocolo de exercício, confirmando nossa hipótese sobre a possível associação entre a força muscular respiratória e a pressão plantar, pela correlação positiva apresentada por algumas variáveis avaliadas. (AU)
There are evidences that postural alteration may influence the functioning of the thoracic cage. However, proper breathing requires good posture and muscle balance. The present study aim was to verify whether there is correlation between a plantar pressure and respiratory muscle strength, as both suffer interference of the postural alterations. We evaluated 30 employees from an a higher Education Institution with the average age between 43,43 ± 13,29 years subdivided into two groups: Experimental group (I) and Control group (II). Group I underwent 30 sessions of respiratory muscle training and at the end of the intervention both groups were reevaluated. The results showed that some plantar pressures undergo significant interference with p < 0.05 in respiratory muscle strength (PEmáx e PEmáx) after exercise protocol confirming our hypothesis about the possible association between respiratory muscle strength and plantar pressure by the positive correlation presented by some variables evaluated. (AU)
Asunto(s)
Humanos , Sistema Respiratorio , Equilibrio Postural , Presiones Respiratorias Máximas , Ejercicios Respiratorios , Caja TorácicaRESUMEN
BACKGROUND: Aspergillus osteomyelitis of the ribs is relatively uncommon. It is a debilitating and severe form of invasive aspergillosis. CASE REPORT: A 61year-old female presented with spontaneous chest pain on the right side of the rib cage and a palpable soft-tissue mass. FDG-PET/CT scan identified activity in the infected site. The lesion was punctured, and purulent material was sent to the laboratory. Aspergillus complex Flavi was isolated. An antifungal treatment with voriconazole was started. The lesion healed, and no recurrence was observed at 8-month follow-up. Molecular identification of the isolate was based on PCR amplification and sequencing of ß-tubulin gene. Aspergillus flavus was identified. CONCLUSIONS: Our case highlights the relevance of microbiological studies in patients with osteomyelitis and the involvement of soft tissue. The FDG-PET/CT scan was found to be a useful tool for revealing the extent of the disease and evaluating the response to the antifungal therapy.
Asunto(s)
Aspergilosis/complicaciones , Aspergillus flavus/aislamiento & purificación , Osteomielitis/microbiología , Caja Torácica , Antifúngicos/uso terapéutico , Aspergilosis/diagnóstico por imagen , Aspergilosis/tratamiento farmacológico , Aspergillus flavus/genética , Femenino , Humanos , Persona de Mediana Edad , Osteomielitis/diagnóstico por imagen , Osteomielitis/tratamiento farmacológico , Tomografía Computarizada por Tomografía de Emisión de Positrones , Caja Torácica/microbiología , Tomografía Computarizada por Rayos X , Voriconazol/uso terapéuticoRESUMEN
Chest wall shape is an important aspect to consider when planning a breast augmentation. Minor chest wall deformities are usually underestimated by the patient and surgeon and may compromise postoperative outcomes. Lower costal cartilage dysmorphia or winged rib is one of these minor underestimated chest wall deformities characterized by a visible and palpable cartilaginous prominence under the inframammary fold and causes discomfort in patients decreasing the satisfaction with the breast augmentation surgery. For these patients, the author utilized an innovative surgical technique that allows resection of the protruding cartilages and placement of breast implants through the same surgical incision. Six patients with winged ribs underwent breast augmentation and costal cartilage resection via this method and there were no intraoperative or early postoperative complications, and all patients were satisfied with the aesthetical result after 6 months of follow-up. The presented surgical technique has a short learning curve with excellent postoperative results. Cases are presented to demonstrate the improved postoperative chest wall contour combined with breast augmentation outcome.Level of Evidence IV This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
Asunto(s)
Implantación de Mama/métodos , Mamoplastia/métodos , Costillas/anomalías , Costillas/cirugía , Adulto , Implantación de Mama/efectos adversos , Implantes de Mama/efectos adversos , Estudios de Cohortes , Estética , Femenino , Estudios de Seguimiento , Humanos , Persona de Mediana Edad , Cuidados Preoperatorios/métodos , Estudios Retrospectivos , Caja Torácica/anomalías , Caja Torácica/cirugía , Factores de Tiempo , Resultado del TratamientoRESUMEN
PURPOSE: The aim of this phase II study was to evaluate the activity and safety of the combination of cisplatin and vinorelbine with thoracic radiotherapy in unresectable locally advanced stage III non-small cell lung cancer (NSCLC). The primary endpoint was the objective response rate (ORR). Secondary objectives included toxicity profile, progression-free survival (PFS), and overall survival (OS). MATERIALS AND METHODS: A total of 48 NSCLC patients were enrolled (median age 60 years, 52% stage IIIA and 48% stage IIIB, 52% adenocarcinoma). Patients received three cycles of chemotherapy every 21 days [intravenous cisplatin 80 mg/m2 and intravenous vinorelbine 25 mg/m2 on day 1 and oral vinorelbine on day 8 (60 mg/m2)] concurrent with radiotherapy (66 Gy, administered at 1.8 Gy per day, five consecutive days per week). RESULTS: ORR was 79.2% (72.9% showing partial response and 6.3% showing complete response). With a median follow-up of 20.7 months, median PFS was 12 months and median OS was 36 months. Grade 3/4 toxicities were: neutropenia (14.5%), anaemia (6.2%), vomiting (2%), and oesophagitis (4.2%). No toxic deaths were reported. CONCLUSION: This combined regimen shows efficacy and a manageable safety profile. PFS and OS outcomes are encouraging and warrant further research.
Asunto(s)
Carcinoma de Pulmón de Células no Pequeñas/terapia , Quimioradioterapia , Neoplasias Pulmonares/terapia , Adulto , Anciano , Carcinoma de Pulmón de Células no Pequeñas/mortalidad , Carcinoma de Pulmón de Células no Pequeñas/patología , Cisplatino/administración & dosificación , Cisplatino/efectos adversos , Progresión de la Enfermedad , Femenino , Humanos , Neoplasias Pulmonares/mortalidad , Neoplasias Pulmonares/patología , Masculino , Persona de Mediana Edad , Estadificación de Neoplasias , Caja Torácica/efectos de la radiación , España/epidemiología , Análisis de Supervivencia , Vinorelbina/administración & dosificación , Vinorelbina/efectos adversosRESUMEN
ABSTRACT Congenital scoliosis associated with costal malformation is well known. However, there are no reports of idiopathic scoliosis associated with the fusion of the costal arcs in the literature. This report describes a case of idiopathic scoliosis with fusion of the 1st and 2nd costal arches in a female patient and reports changes in the deformity due to scoliosis because of the treatment. The analysis was performed from a morphological and clinical point of view, and by complementary tests. Radiographs and CT scans were obtained and evaluated from the first consultation in 2012 and during the period in which the patient was followed in a private clinic, until the stabilization of the condition, in 2014. The evolution was favorable with the use of a Milwaukee vest and there was improvement of the clinical picture after the skeletal maturity, and the angle of lateral curvature, measured by the Cobb method, initially of 20 degrees, was reduced and stabilized in nine degrees, measure which is currently maintained. The analysis showed concomitant pathologies, and the fusion of costal arches did not influence the spine deformity, since there was regression with the clinical treatment. This evolution leads us to conclude that adolescent idiopathic scoliosis should be imputed as the sole responsible for the clinical picture of the patient, and that the fusion of the costal arches does not interfere with the biomechanics of the spine. Level of Evidence: IV. Type of study: Case series.
RESUMO A escoliose congênita associada à malformação costal é bem conhecida. Porém, não existe na literatura relatos de escoliose idiopática associada à fusão dos arcos costais. Este relato descreve um caso de escoliose idiopática com a fusão do 1º e 2º arcos costais em paciente do sexo feminino, e relata modificações da deformidade por escoliose em decorrência do tratamento. A análise foi realizada do ponto de vista morfológico, clínico e por exames complementares. Foram avaliadas radiografias e tomografias obtidas desde a primeira consulta, em 2012, e durante o período em que a mesma foi acompanhada em uma clínica particular, até a estabilização do quadro em 2014. A evolução foi favorável com uso de colete de Milwaukee e houve melhora do quadro clínico após maturidade esquelética, sendo que o ângulo de curvatura lateral, aferido pelo método de Cobb, inicialmente de 20 graus, reduziu e se estabilizou em nove graus, sendo que esta medida se mantém atualmente. Pela análise realizada, houve uma concomitância de patologias, sendo que a fusão de arcos costais não influenciou na deformidade da coluna, uma vez que a mesma regrediu com o tratamento clínico. Esta evolução nos leva a concluir que a escoliose idiopática da adolescente deve ser imputada como a única responsável pelo quadro clínico da paciente, e que a fusão dos arcos costais não interfere na biomecânica da coluna vertebral. Nível de Evidência: IV. Tipo de estudo: Série de caso.
RESUMEN La escoliosis congénita asociada a la malformación costal es bien conocida. Sin embargo, no existen relatos de escoliosis idiopática asociada a la fusión de los arcos costales en la literatura. Este relato describe un caso de escoliosis idiopática con la fusión del primer y segundo arco costal en paciente del sexo femenino y relata modificaciones de la deformidad por escoliosis como consecuencia del tratamiento. El análisis fue realizado desde el punto de vista morfológico y clínico y por exámenes complementarios. Se evaluaron las radiografías y tomografías obtenidas en la primera consulta, en 2012 y durante el período en el que la paciente fue acompañada en una clínica particular, hasta la estabilización del cuadro, en 2014. La evolución fue favorable con uso de chaleco de Milwaukee y hubo una mejora del cuadro clínico después de la madurez esquelética, siendo que el ángulo de curvatura lateral, medido por el método de Cobb, inicialmente de 20 grados, se redujo y se estabilizó en nueve grados, lo que se mantiene actualmente. Por el análisis realizado, hubo concomitancia de patologías, siendo que la fusión de arcos costales no influenció la deformidad de la columna, una vez que hubo regresión con el tratamiento clínico. Esta evolución nos lleva a concluir que la escoliosis idiopática de esta adolescente debe ser imputada como la única responsable del cuadro clínico de la paciente, y que la fusión de los arcos costales no interfiere en la biomecánica de la columna vertebral. Nivel de Evidencia: IV. Tipo de estudio: Serie de caso.
Asunto(s)
Humanos , Femenino , Adolescente , Escoliosis , Costillas , Diagnóstico por Imagen , Caja TorácicaRESUMEN
OBJECTIVES: According to eco-geographic rules, humans from high latitude areas present larger and wider trunks than their low-latitude areas counterparts. This issue has been traditionally addressed on the pelvis but information on the thorax is largely lacking. We test whether ribcages are larger in individuals inhabiting high latitudes than in those from low latitudes and explored the correlation of rib size with latitude. We also test whether a common morphological pattern is exhibited in the thorax of different cold-adapted populations, contributing to their hypothetical widening of the trunk. MATERIALS AND METHODS: We used 3D geometric morphometrics to quantify rib morphology of three hypothetically cold-adapted populations, viz. Greenland (11 individuals), Alaskan Inuit (8 individuals) and people from Tierra del Fuego (8 individuals), in a comparative framework with European (Spain, Portugal and Austria; 24 individuals) and African populations (South African and sub-Saharan African; 20 individuals). RESULTS: Populations inhabiting high latitudes present longer ribs than individuals inhabiting areas closer to the equator, but a correlation (p < 0.05) between costal size and latitude is only found in ribs 7-11. Regarding shape, the only cold adapted population that was different from the non-cold-adapted populations were the Greenland Inuit, who presented ribs with less curvature and torsion. CONCLUSIONS: Size results from the lower ribcage are consistent with the hypothesis of larger trunks in cold-adapted populations. The fact that only Greenland Inuit present a differential morphological pattern, linked to a widening of their ribcage, could be caused by differences in latitude. However, other factors such as genetic drift or specific cultural adaptations cannot be excluded and should be tested in future studies.
Asunto(s)
Adaptación Biológica/fisiología , Antropometría/métodos , Frío , Imagenología Tridimensional/métodos , Caja Torácica , Alaska , Antropología Física , Argentina , Chile , Groenlandia , Humanos , Indígenas Norteamericanos , Caja Torácica/diagnóstico por imagen , Caja Torácica/fisiología , Población BlancaRESUMEN
Este estudo teve por objetivo desenvolver um modelo matemático que a partir da extensão do osso esterno fornecesse o tamanho do pulmão compatível para o receptor. Foram coletadas as medidas antropométricas do tórax de 250 indivíduos, através de exame de tomografia computadorizada. Os resultados apontam que a medida do osso esterno (distância da incisura jugular até processo xifóide) apresenta correlação positiva com todas as outras medidas do tórax (medida ântero-posterior e látero-medial entre II e III costela, e ápice à base de ambos os pulmões). Entretanto, o volume pulmonar e sua relação com o osso esterno apresentam discrepâncias quando analisados sob a correlação de Pearson, pois a relação entre a medida da incisura jugular ao processo xifóide e a medida do ápice à base do pulmão direito e esquerdo, apresenta correlação positiva média (0,31-0,6). Já a medida da incisura jugular ao processo xifóide com a medida ântero-posterior e látero-medial do tórax, apresenta correlação significativa baixa (0-0,3). Então, a análise estatística da correlação de Pearson demonstrou ser inviável o desenvolvimento da fórmula, pois esta não seria confiável já que funcionaria para cerca de apenas 39% dos pacientes. Assim, o melhor método para determinar o doador para o transplante, continua sendo a análise de fatores de risco, a capacidade vital forçada do doador e receptor com estatura maior do que a do doador.
This study aimed at developing a mathematical model that can provide the compatible lung size for the recipient from the length of the sternum bone. Anthropometric chest measurements of 250 individuals were collected through a CT scan. The results indicate that the measurement of the sternum bone (distance from the jugular notch to the xiphoid process) shows a positive correlation with all other thorax measurements (antero-posterior and medial-posterior measurement between ribs II and III, and apex-to-base on both lungs). However, lung volume and its correlation to the sternal bone present discrepancies when analyzed under Pearson's correlation, since the relation between the jugular notch measurement and the apex measurement at the base of the right and left lungs shows a positive correlation mean (0.31-0.6). The measurement of the jugular notch in the xiphoid process with the anterior-posterior and medial-medial measurements, presents a low significant correlation (0-0.3). Therefore, the statistical analysis of the Pearson's correlation showed that the formula could not be applied since it would not be reliable since it would work for only 39% of the patients. Thus, the best method to determine the donor for transplantation remains the analysis of risk factors, the forced vital capacity of the donor, and the recipient being taller than the donor.
Asunto(s)
Trasplante , Caja Torácica/anatomía & histología , Histocompatibilidad , PulmónRESUMEN
ABSTRACT The spine presents distinct mobility and characteristics according to the anatomical region, and there are several instruments that allow it to be assessed. This systematic review aimed to identify methods and instruments used to assess the range of motion of the thoracic and lumbar spine in the sagittal plane, with confirmed validity and/or repeatability and/or reproducibility, evidencing their respective psychometric indexes. Searches were conducted on BIREME, EMBASE, PEDro, PubMed, Science Direct, SCOPUS and Web of Science databases, and there were manual searches as well. Two independent reviewers selected the studies, extracted data, evaluated methodological quality, risk of bias, and evidence (GRADE). A total of 46 studies were included in the qualitative analysis, seven of which only were included in the quantitative analysis. There is scientific evidence, confirmed by meta-analysis, on the inter-rater reproducibility of the measuring tape instrument in the modified Schöber's test for lumbar flexion, and the intra-rater reproducibility of the Flexicurve and video analysis system instruments for lumbar extension and flexion. Besides, based on GRADE criteria, there is still little scientific evidence on the validity, repeatability and reproducibility of the instruments and methods indicated for assessing the range of motion of the thoracic and lumbar spine in the sagittal plane.
RESUMO A coluna vertebral apresenta mobilidade e características distintas conforme a região anatômica, e, há diversos instrumentos que propiciam sua avaliação. Esta revisão sistemática objetivou identificar os métodos e instrumentos utilizados para avaliar a amplitude de movimento da coluna vertebral torácica e lombar no plano sagital que apresentam validade e/ou repetibilidade e/ou reprodutibilidade confirmados, evidenciando seus respectivos índices psicométricos. Foram realizadas buscas nas bases de dados BIREME, EMBASE, PEDro, PubMed, Science Direct, SCOPUS e Web of Science, além de buscas manuais. Dois revisores independentes realizaram a seleção dos estudos, extraíram os dados, avaliaram a qualidade metodológica, o risco de viés e a evidência (GRADE). Foram incluídos 46 estudos na análise qualitativa, e destes, apenas sete foram incluídos na análise quantitativa. Há evidência científica, confirmada por metanálise, acerca da reprodutibilidade interavaliador do instrumento fita métrica no teste de Schöber modificado para flexão lombar e da reprodutibilidade intra-avaliador dos instrumentos flexicurva e sistema de análise de vídeo para a extensão e flexão lombar. E, com base nos critérios do GRADE, ainda há baixa evidência científica sobre a validade, repetibilidade e reprodutibilidade dos instrumentos e métodos indicados para a avaliação da amplitude de movimento articular da coluna vertebral torácica e lombar no plano sagital.
Asunto(s)
Columna Vertebral , Rango del Movimiento Articular , Caja TorácicaRESUMEN
OBJECTIVE:: To review the literature on the effects of expiratory rib cage compression on ventilatory mechanics, airway clearance, and oxygen and hemodynamic indices in mechanically ventilated adults. METHODS:: Systematic review with meta-analysis of randomized clinical trials in the databases MEDLINE (via PubMed), EMBASE, Cochrane CENTRAL, PEDro, and LILACS. Studies on adult patients hospitalized in intensive care units and under mechanical ventilation that analyzed the effects of expiratory rib cage compression with respect to a control group (without expiratory rib cage compression) and evaluated the outcomes static and dynamic compliance, sputum volume, systolic blood pressure, diastolic blood pressure, mean arterial pressure, heart rate, peripheral oxygen saturation, and ratio of arterial oxygen partial pressure to fraction of inspired oxygen were included. Experimental studies with animals and those with incomplete data were excluded. RESULTS:: The search strategy produced 5,816 studies, of which only three randomized crossover trials were included, totaling 93 patients. With respect to the outcome of heart rate, values were reduced in the expiratory rib cage compression group compared with the control group [-2.81 bpm (95% confidence interval [95%CI]: -4.73 to 0.89; I2: 0%)]. Regarding dynamic compliance, there was no significant difference between groups [-0.58mL/cmH2O (95%CI: -2.98 to 1.82; I2: 1%)]. Regarding the variables systolic blood pressure and diastolic blood pressure, significant differences were found after descriptive evaluation. However, there was no difference between groups regarding the variables secretion volume, static compliance, ratio of arterial oxygen partial pressure to fraction of inspired oxygen, and peripheral oxygen saturation. CONCLUSION:: There is a lack of evidence to support the use of expiratory rib cage compression in routine care, given that the literature on this topic offers low methodological quality and is inconclusive.