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1.
Curr Neurol Neurosci Rep ; 24(11): 561-569, 2024 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-39259429

RESUMEN

PURPOSE OF REVIEW: This review aims to rediscuss the leading theories concerning the role of basal ganglia and the thalamus in the genesis of aphasic symptoms in the absence of gross anatomical lesions in cortical language areas as assessed by conventional neuroimaging studies. RECENT FINDINGS: New concepts in language processing and modern neuroimaging techniques have enabled some progress in resolving the impasse between the current dominant theories: (a) direct and specific linguistic processing and (b) subcortical structures as processing relays in domain-general functions. Of particular interest are studies of connectivity based on functional magnetic resonance imaging (MRI) and tractography that highlight the impact of white matter pathway lesions on aphasia development and recovery. Connectivity studies have put into evidence the central role of the arcuate fasciculus (AF), inferior frontal occipital fasciculus (IFOF), and uncinate fasciculus (UF) in the genesis of aphasia. Regarding the thalamus, its involvement in lexical-semantic processing through modulation of the frontal cortex is becoming increasingly apparent.


Asunto(s)
Afasia , Tálamo , Humanos , Afasia/fisiopatología , Afasia/diagnóstico por imagen , Afasia/etiología , Afasia/patología , Tálamo/diagnóstico por imagen , Tálamo/fisiopatología , Tálamo/patología , Ganglios Basales/diagnóstico por imagen , Ganglios Basales/fisiopatología , Ganglios Basales/patología , Vías Nerviosas/fisiopatología , Vías Nerviosas/diagnóstico por imagen , Encéfalo/diagnóstico por imagen , Encéfalo/patología , Encéfalo/fisiopatología , Imagen por Resonancia Magnética
2.
Cortex ; 178: 287-298, 2024 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-39084164

RESUMEN

Pauses in speech are indicators of cognitive effort during language production and have been examined to inform theories of lexical, grammatical and discourse processing in healthy speakers and individuals with aphasia (IWA). Studies of pauses have commonly focused on their location and duration in relation to grammatical properties such as word class or phrase complexity. However, recent studies of speech output in aphasia have revealed that utterances of IWA are characterised by stronger collocations, i.e., combinations of words that are often used together. We investigated the effects of collocation strength and lexical frequency on pause duration in comic strip narrations of IWA and non-brain-damaged (NBD) individuals with part of speech (PoS; content and function words) as covariate. Both groups showed a decrease in pause duration within more strongly collocated bigrams and before more frequent content words, with stronger effects in IWA. These results are consistent with frameworks which propose that strong collocations are more likely to be processed as holistic, perhaps even word-like, units. Usage-based approaches prove valuable in explaining patterns of preservation and impairment in aphasic language production.


Asunto(s)
Afasia , Habla , Humanos , Afasia/fisiopatología , Habla/fisiología , Masculino , Femenino , Persona de Mediana Edad , Anciano , Adulto , Lenguaje
3.
Folia Phoniatr Logop ; 76(5): 482-490, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38219713

RESUMEN

INTRODUCTION: It is important to analyze the micro- and macrostructure of connected language production across languages in neurotypical and impaired speakers such as people with aphasia (PWA). However, the validity, reliability, sensitivity, or specificity of the available Brazilian-Portuguese connected language production batteries remains untested. OBJECTIVE: The purpose of this study was to provide a preliminary assessment of the translated Brazilian-Portuguese Story Retell Procedure (SRP-BP) in PWA and neurotypical control participants (NCPs) and investigate whether the SRP can serve as a measure of overall communication impairment in PWA. METHODS: This cross-sectional study was developed at the Federal University of São Paulo. Seven right-handed PWA and 14 NCPs were recruited. PWA had a single left-hemisphere post-stroke lesion and were without severe aphasia or non-fluent aphasia that might interfere with performing the SRP. The connected language measures calculated from the SRP-BP were the numbers of words, information units, and propositions produced. The data were analyzed with the non-parametric Mann-Whitney test. RESULTS: The NCPs produced significantly more information units and propositions in each of the 12 SRP-BP stories than the PWA group. The same group results were found for the number of words for 11 of the 12 stories, with no statistically significant difference between groups for the Água (Water) story. CONCLUSION: The SRP-BP distinguished the connected language production of PWA from that of NCPs. These results motivate additional psychometric assessment and test development of the SRP-BP in neurotypical, PWA, and other language and cognitively impaired populations.


Asunto(s)
Afasia , Humanos , Masculino , Brasil , Femenino , Persona de Mediana Edad , Estudios Transversales , Afasia/etiología , Adulto , Anciano , Accidente Cerebrovascular/complicaciones , Reproducibilidad de los Resultados , Lenguaje , Pruebas del Lenguaje
4.
Folia Phoniatr Logop ; 76(2): 172-182, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-37557086

RESUMEN

INTRODUCTION: The comprehension and production of connected language are essential for effective communication. However, few assessment and intervention programs requiring connected language have been made available in Brazilian Portuguese. One connected language sampling procedure, the Story Retell Procedure (SRP), has been widely studied in English and primarily for people with aphasia. The SRP employs 12 stories, whose individual plots are quite different and still equivalent in terms of verbal productivity measures. The first objective of this study was to present the translation and adaptation of the SRP stories into Portuguese and to determine whether the translations are similar to English stories. The second objective was to analyze a small group of healthy adults' responses to this assessment, thus observing whether the retellings of the SRP story forms in Portuguese would be similar to each other in the number of words, information units (IUs), and propositions - as demonstrated in English. METHODS: This preliminary study translated and adapted into Portuguese, the 12 original English SRP stories. Only small cultural adaptations were made, preserving the essential content of the stories. The stories were then presented to 14 healthy adults, and the participants' retellings from each story were compared to the other stories regarding the number of words, IUs, and propositions. RESULTS: Few differences were found in the retellings considering the variables analyzed. Particularly, the retells of Gasolina (Gas), Biblioteca (Library), Empréstimo (Loan), Sanduíche (Sandwich), Futebol (Baseball), and Multas (Ticket) were not significantly different in the three aspects investigated in this study (percentages of words, IUs, and propositions). CONCLUSION: The SRP stories adapted to Portuguese, despite having a quite close number of words, IUs, and propositions to those in the original stories, did not result in retellings with similar number of words, IUs, or propositions across stories. Nonetheless, the parameters analyzed were not significantly different among the majority of the stories, and some were nearly identical. This study identified the SRP stories that can be equivalently used in assessment, reassessment, and possibly in the rehabilitation of patients with communication disorders. Likewise, differences must be considered when the stories are used with pathological populations.


Asunto(s)
Afasia , Lenguaje , Adulto , Humanos , Niño , Portugal , Lenguaje Infantil , Pruebas del Lenguaje , Brasil
5.
NeuroRehabilitation ; 53(4): 585-594, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37927287

RESUMEN

BACKGROUND: Some research suggests that post-stroke aphasia can recover "on its own", however, there is evidence of a common neural substrate for motor and language systems. We hypothesize, that motor neurorehabilitation of hemiparesis could be related to simultaneous improvement in aphasia. OBJECTIVE: To measure changes in post-stroke aphasia and its relation with hemiparesis treated with different therapies. METHODS: Database information (n = 32) on post-stroke hemiparesis (Fugl-Meyer Scale evaluated) managed with virtual reality (VR) versus modified constraint-induced movement therapy (mCIMT) or regular therapy (rPT/OT) was analyzed. None received logotherapy (LT) by appointment at four months. INCLUSION CRITERIA: < 3 months after the stroke, aphasia severe (Boston Aphasia Intensity Scale), and all three evaluations. RESULTS: Twenty-one patient records met inclusion criteria (71,4% women and mean age 66,67±3,13 years) who received VR, mCIMT, or rPT/OT (n = 6, 8, and 7, respectively). There was continuous intra-groups improvement in aphasia (p < 0.05), but inter-groups the greater aphasia recovery (p = 0.05) and hemiparesis (p = 0.02) were in VR, with a high correlation in evolution between them (r = 0.73; p = 0.047). CONCLUSION: High clinical correlation between aphasia, without LT, and hemiparesis evolution during motor neurorehabilitation would support common neural connections stimulation. We will conduct a clinical trial, with a larger sample size to contrast our hypothesis.


Asunto(s)
Afasia , Rehabilitación Neurológica , Rehabilitación de Accidente Cerebrovascular , Accidente Cerebrovascular , Realidad Virtual , Femenino , Humanos , Masculino , Afasia/etiología , Logoterapia , Paresia/etiología , Paresia/rehabilitación , Recuperación de la Función , Estudios Retrospectivos , Accidente Cerebrovascular/complicaciones , Accidente Cerebrovascular/terapia , Persona de Mediana Edad , Anciano
6.
Distúrb. comun ; 35(3)25/10/2023.
Artículo en Inglés, Portugués | LILACS | ID: biblio-1526056

RESUMEN

Introdução: A compreensão da afasia é fundamental para os profissionais de saúde que prestam assistência a pacientes com AVC. No entanto, a informação disponível sobre a afasia ainda é limitada e insuficiente para uma abordagem eficaz. É de suma importância identificar o conhecimento dos profissionais de saúde a respeito da afasia, a fim de planejar o atendimento aos pacientes e suas famílias.Objetivo: Avaliar o nível de conhecimento dos profissionais de saúde de um hospital público em relação à afasia e analisar como eles lidam com pacientes com afasia durante o período de hospitalização. Método: Realizamos uma pesquisa com profissionais de saúde por meio de um questionário online para avaliar seu conhecimento sobre a afasia e suas estratégias de atendimento. Resultados: Os resultados indicam que profissionais de saúde com níveis de educação mais elevados tendem a possuir um entendimento mais sólido da afasia. No entanto, persistem lacunas de conhecimento em diversos aspectos da afasia. Embora a maioria dos profissionais se sinta adequadamente preparado para lidar com pacientes com afasia, eles reconhecem os desafios envolvidos e expressam o desejo de receber orientações para aprimorar suas habilidades de comunicação. Conclusão: Este estudo ressalta a necessidade de uma formação mais abrangente para os profissionais de saúde no que diz respeito à afasia e suas estratégias de comunicação. É fundamental o desenvolvimento de programas de treinamento e a elaboração de diretrizes específicas para os profissionais que atuam com esses pacientes, visando proporcionar um atendimento de alta qualidade. (AU)


Introduction: Understanding aphasia is crucial for healthcare professionals providing care to stroke patients. However, there is a need to enhance and refine the information available about aphasia for practical application. It is imperative to assess the knowledge of healthcare professionals regarding aphasia to facilitate effective care planning for patients and their families. Objective: This study aims to evaluate the level of knowledge among healthcare professionals in a public hospital concerning aphasia and their approach to patients with aphasia during their hospitalization. Method: An online questionnaire was administered to healthcare professionals to assess their understanding of aphasia and their caregiving strategies. Results: The findings indicate that healthcare professionals with higher education levels tend to have a better understanding of aphasia. Nevertheless, knowledge gaps persist in various aspects of aphasia. While most professionals feel adequately prepared to interact with patients experiencing aphasia, they acknowledge the challenges involved and express a desire for guidance to enhance their communication skills. Conclusion: This study underscores the necessity for comprehensive training of healthcare professionals in the realm of aphasia and effective communication strategies. The development of training programs and guidelines is crucial to better serve patients with aphasia, ensuring the provision of high-quality care. (AU)


Introducción: La comprensión de la afasia es importante para los profesionales de la salud que atienden a pacientes con ACV. Sin embargo, la información sobre la afasia sigue siendo limitada e insuficiente para un enfoque efectivo. Es importante identificar el conocimiento de los profesionales de la salud sobre la afasia para planificar la atención a los pacientes y sus familias. Objetivo: Evaluar el conocimiento de los profesionales de la salud de un hospital público sobre la afasia y cómo manejan a los pacientes con afasia durante el período de hospitalización. Método: Se realizó una encuesta a profesionales de la salud a través de un cuestionario en línea para evaluar su conocimiento sobre la afasia y sus tácticas de atención. Resultados: Se señala un mayor conocimiento sobre la afasia entre los profesionales de nivel superior, pero aún existen lagunas de conocimiento en varios aspectos de la afasia. La mayoría de los profesionales se sienten preparados para manejar a pacientes con afasia, pero reconocen que la atención es desafiante y les gustaría recibir orientación para mejorar sus habilidades de comunicación. Conclusión:Este estudio destaca la necesidad de una formación más amplia y completa para los profesionales de la salud sobre la afasia y su comunicación. Es fundamental desarrollar programas de capacitación y guías para atender mejor a estos pacientes y garantizar una atención de calidad. (AU)


Asunto(s)
Humanos , Afasia/etiología , Conocimientos, Actitudes y Práctica en Salud , Estudios Transversales , Encuestas y Cuestionarios , Personal de Salud/educación , Accidente Cerebrovascular/complicaciones , Hospitalización , Hospitales Públicos
7.
Am J Speech Lang Pathol ; 32(6): 2768-2791, 2023 11 06.
Artículo en Inglés | MEDLINE | ID: mdl-37678193

RESUMEN

PURPOSE: This mixed-methods research sought to examine the experience of people with aphasia who used text-to-speech (TTS) support to read a novel for virtual book club participation. METHOD: Six people with chronic aphasia used a TTS system to review portions of a novel about which they conversed during eight virtual book club meetings occurring over 5 weeks. During one-on-one interactions prior to each meeting, participants answered comprehension questions and provided feedback about reading experiences. Then, during group meetings, they reviewed and discussed relevant book content and predicted upcoming content. During a structured individual interview, participants reflected on their supported reading and book club experience. RESULTS: Participants reported a range of reading confidence prior to study participation, mostly influenced by decreased comprehension or reading speed. After book club participation, four participants expressed increased confidence. Some reported searching for key words and skipping difficult words as strategies additional to TTS support. All reviewed at least some book sections more than once either with or without TTS support. Highly motivated participants expressed low frustration and high reading ease and enjoyment. Perceived comprehension was roughly consistent with actual comprehension across participants. Most believed TTS support promoted faster reading than otherwise possible. Participants liked adjustable features affecting speech output rate, word or sentence highlighting, and font size. Psychosocial benefits included decreased isolation and increased friendship. CONCLUSIONS: The findings extend previous evidence about perceived and actual benefits associated with TTS support. People with aphasia express positive experiences when given TTS support during book club participation.


Asunto(s)
Afasia , Habla , Humanos , Afasia/psicología , Comprensión , Lectura , Tecnología
8.
J Speech Lang Hear Res ; 66(7): 2296-2315, 2023 07 12.
Artículo en Inglés | MEDLINE | ID: mdl-37410632

RESUMEN

BACKGROUND: There is a lack of standardized assessment tools for poststroke aphasia in Brazil, particularly bedside screenings for early identification of patients with suspected language disorders. The Language Screening Test (LAST) is a valid and reliable method for screening hospitalized patients following a stroke. This tool was first developed in French and then translated and validated in other languages. PURPOSE: This study aimed to translate, culturally adapt, and validate the LAST into Brazilian Portuguese. METHOD: Following a systematic, multistep approach to translation and cultural adaptation of language instruments, this study developed the two parallel versions of the Brazilian Portuguese LAST (pLAST) Versions A and B. The final versions were applied to 70 healthy and 30 poststroke adults across age and educational levels. Subtests of the Boston Diagnostic Aphasia Examination (BDAE) were used to assess the external validity of the pLAST. RESULTS: Findings showed that the two versions (A and B) of the pLAST were equivalent (intraclass correlation coefficient = .91; p < .001). No floor or ceiling effects were observed, and internal validity was excellent (Cronbach's α = .85). Moreover, its external validity against the BDAE was moderate to strong. Test sensitivity and specificity were 0.88 and 1, respectively, and accuracy was 0.96. CONCLUSION: The Brazilian Portuguese version of the LAST is a valid, simple, easy, and rapid test to screen poststroke aphasia in hospital settings. SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.23548911.


Asunto(s)
Afasia , Pruebas del Lenguaje , Encuestas y Cuestionarios , Adulto , Humanos , Afasia/diagnóstico , Afasia/etiología , Brasil , Reproducibilidad de los Resultados , Accidente Cerebrovascular/complicaciones , Traducciones , Comparación Transcultural , Masculino , Femenino , Persona de Mediana Edad
9.
Am J Speech Lang Pathol ; 32(5S): 2580-2588, 2023 10 17.
Artículo en Inglés | MEDLINE | ID: mdl-37486768

RESUMEN

PURPOSE: The goal of the Collaborative Commentary (CC) system is to make the TalkBank adult clinical databases-including AphasiaBank, DementiaBank, RHDBank, and TBIBank-open to commentary and analysis from the full community of researchers, instructors, students, and clinicians. METHOD: CC allows a group leader to establish a commentary group and invite colleagues or students to join as members of the group. Members can then browse through the transcript database using the TalkBank Browser. When they wish to insert a comment, they click on the utterance line number or drag the cursor across a range of utterances and a window opens to receive the comment. The comment can include open text along with codes selected from a predefined set of codes created by that commentary group. RESULTS: CC was released for public use in August 2022. It is being used currently in five research projects and eight classes. An important feature of CC is its ability to evaluate the reliability of coding systems and to sharpen analytic categories. By familiarizing instructors and researchers with the capabilities of CC, we expect to see an increasing usage of CC for a variety of clinical and research applications. CONCLUSIONS: CC can contribute to a better understanding of connected speech features in aphasia, dementia, right hemisphere disorder, and traumatic brain injury. CC represents an extreme innovation not only for the study of adult neurogenic communication disorders but also for the study of spoken language generally.


Asunto(s)
Afasia , Lesiones Traumáticas del Encéfalo , Trastornos de la Comunicación , Adulto , Humanos , Reproducibilidad de los Resultados , Trastornos de la Comunicación/diagnóstico , Habla , Afasia/diagnóstico , Comunicación
10.
PeerJ ; 11: e15518, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37334126

RESUMEN

Aphasia is a language disorder that occurs after brain injury and directly affects an individual's communication. The incidence of stroke increases with age, and one-third of people who have had a stroke develop aphasia. The severity of aphasia changes over time and some aspects of language may improve, while others remain compromised. Battery task training strategies are used in the rehabilitation of aphasics. The idea of this research is to use electroencephalography (EEG) as a non-invasive method, of electrophysiological monitoring, with a group of aphasic patients in rehabilitation process in a prevention and rehabilitation unit of the person with disabilities of the Unified Health System (SUS), of reference in the state of Bahia-Brazil. In this study, the goal is to analyze brain activation and wave frequencies of aphasic individuals during a sentence completion task, to possibly assist health professionals with the analysis of the aphasic subject's rehabilitation and task redefinition. We adopted the functional magnetic resonance imaging (fMRI) paradigm, proposed by the American Society for Functional Neuroradiology as a reference paradigm. We applied the paradigm in the group of aphasics with preserved comprehension, right hemiparesis, and left hemisphere injured or affected by stroke. We analyzed four electrodes (F3/F4 and F7/F8) corresponding to the left/right frontal cortex. Preliminary results of this study indicate a more robust activation in the right hemisphere (average of aphasics), with a difference of approximately 14% higher in Theta and Alpha frequencies, with 8% higher in low Beta (BetaL) and with approximately 1% higher in high Beta frequency (BetaH), Gamma frequency was higher by approximately 3% in the left hemisphere of the brain. The difference in electrical activation may be revealing to us a migration of language to the non-language dominant hemisphere. We point to possible evidence suggesting that EEG may be a promising tool for monitoring the rehabilitation of the aphasic subject.


Asunto(s)
Afasia , Accidente Cerebrovascular , Humanos , Encéfalo/diagnóstico por imagen , Afasia/etiología , Accidente Cerebrovascular/complicaciones , Lenguaje , Electroencefalografía/efectos adversos
11.
Epileptic Disord ; 25(1): 104-109, 2023 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-37070376

RESUMEN

Ictal clinical phenomenology, including aphasia, is usually associated with increased regional cerebral perfusion. We present an unusual pattern of ictal cerebral perfusion in three patients with pharmacoresistant, lesional temporal lobe epilepsy and ictal/postictal aphasia studied with prolonged video-EEG, ictal, and interictal SPECT and MRI for pre-surgical evaluation. Subtraction of ictal-interictal SPECT images co-registered with MRI (SISCOM) showed ictal hyperperfusion in the temporal epileptogenic area in all patients. In addition, hypoperfusion of Broca's area in one case, Wernicke's area in other patient, and both areas in the remaining one were observed. Ictal aphasia in these patients may be explained by functional inhibition of a primary language area, driven by the epileptogenic network. This pattern can contribute to understand the pathophysiology of some ictal signs, with an impact on the evaluation of individual surgical risks.


Asunto(s)
Afasia , Epilepsia del Lóbulo Temporal , Humanos , Epilepsia del Lóbulo Temporal/cirugía , Tomografía Computarizada de Emisión de Fotón Único/métodos , Imagen por Resonancia Magnética/métodos , Electroencefalografía , Afasia/etiología , Encéfalo
12.
J Speech Lang Hear Res ; 66(4): 1351-1364, 2023 04 12.
Artículo en Inglés | MEDLINE | ID: mdl-37014997

RESUMEN

PURPOSE: The purpose of this study was to evaluate whether a short-form computerized adaptive testing (CAT) version of the Philadelphia Naming Test (PNT) provides error profiles and model-based estimates of semantic and phonological processing that agree with the full test. METHOD: Twenty-four persons with aphasia took the PNT-CAT and the full version of the PNT (hereinafter referred to as the "full PNT") at least 2 weeks apart. The PNT-CAT proceeded in two stages: (a) the PNT-CAT30, in which 30 items were selected to match the evolving ability estimate with the goal of producing a 50% error rate, and (b) the PNT-CAT60, in which an additional 30 items were selected to produce a 75% error rate. Agreement was evaluated in terms of the root-mean-square deviation of the response-type proportions and, for individual response types, in terms of agreement coefficients and bias. We also evaluated agreement and bias for estimates of semantic and phonological processing derived from the semantic-phonological interactive two-step model (SP model) of word production. RESULTS: The results suggested that agreement was poorest for semantic, formal, mixed, and unrelated errors, all of which were underestimated by the short forms. Better agreement was observed for correct and nonword responses. SP model weights estimated by the short forms demonstrated no substantial bias but generally inadequate agreement with the full PNT, which itself showed acceptable test-retest reliability for SP model weights and all response types except for formal errors. DISCUSSION: Results suggest that the PNT-CAT30 and the PNT-CAT60 are generally inadequate for generating naming error profiles or model-derived estimates of semantic and phonological processing ability. Post hoc analyses suggested that increasing the number of stimuli available in the CAT item bank may improve the utility of adaptive short forms for generating error profiles, but the underlying theory also suggests that there are limitations to this approach based on a unidimensional measurement model. SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.22320814.


Asunto(s)
Afasia , Humanos , Afasia/diagnóstico , Lingüística , Reproducibilidad de los Resultados , Semántica
13.
Photobiomodul Photomed Laser Surg ; 41(5): 234-240, 2023 May.
Artículo en Inglés | MEDLINE | ID: mdl-36999917

RESUMEN

Objective: This is a case report showing that transcranial photobiomodulation (tPBM) combined with traditional, speech-language therapy improved and accelerated the results from speech-language therapy, in a stroke person with aphasia (PWA). Background: tPBM is a safe, noninvasive technique using red and near-infrared light to improve the metabolism of cells. tPBM helps by promoting neuromodulation, while decreasing neuroinflammation and promoting vasodilation. Several studies have shown that tPBM can help individuals with stroke or traumatic brain injury achieve significant cognitive improvements. Methods: A 38-year-old female, who sustained an ischemic stroke on the left side of the brain, received two, 5-month series of treatments. The first series of treatments included traditional speech-language therapy, for the first 5 months poststroke. The second series of treatments included tPBM in combination with speech-language therapy, for the next 5 months. The tPBM treatments included application of red (630 and 660 nm) and near-infrared (850 nm) wavelengths of photons applied to left hemisphere scalp areas. The major cortical language areas were subjacent to the scalp placements along the line of the Sylvian fissure. At each session, first a light-emitting diode (LED) cluster head with red (630 and 660 nm) and near-infrared (850 nm) wavelengths, with an irradiance (power density) of 200 mW/cm2, a beam size of 4.9 cm2, and a fluence (energy density) of 12 J/cm2 per minute, was applied to the left side of the scalp/brain, along the Sylvian fissure for 60 sec at each at the following eight, language network target areas: frontal pole, prefrontal cortex, and inferior frontal gyrus (Broca's area); supramarginal gyrus and angular gyrus in the parietal lobe; inferior motor/sensory cortex (mouth area); and posterior superior temporal gyrus (Wernicke's area) and superior temporal sulcus in the temporal lobe, for a total of 8 min. Second, for the next 20 min (1200 sec), simultaneous with speech-language therapy, an LED PBM helmet was applied to the scalp/head. This helmet contained 256 separate LED lights, near-infrared (810 nm) wavelength, 60 mW power per LED light, total power, 15 W; energy, 72 Joules; fluence, 28.8 J/cm2; and irradiance, 24 mW/cm2. Results and conclusions: During the initial, 5-month treatment series with traditional speech-language therapy only, there was little to no improvement in dysarthria and expressive language. During the second, 5-month treatment series, however, with tPBM applied first, to the left hemisphere only, and second, to both hemispheres during each session plus simultaneous speech-language therapy, there was marked improvement in the dysarthria and expressive language. After the first 5-month series, this PWA had utilized a slow rate of speech with a production of ∼25 to 30 words-per-minute during conversations and spontaneous speech. Utterance length was only 4-6 words with simple, grammatical structure. After the second, 5-month series of treatment combining tPBM plus speech-language therapy, the rate of speech increased to 80+ words-per-minute and utterance length was increased to 9-10 words, with more complex grammatical structure.


Asunto(s)
Afasia , Accidente Cerebrovascular , Femenino , Humanos , Adulto , Habla , Disartria , Terapia del Lenguaje , Afasia/terapia , Accidente Cerebrovascular/radioterapia , Cognición
14.
J Speech Lang Hear Res ; 66(6): 1908-1927, 2023 06 20.
Artículo en Inglés | MEDLINE | ID: mdl-36542852

RESUMEN

PURPOSE: Small-N studies are the dominant study design supporting evidence-based interventions in communication science and disorders, including treatments for aphasia and related disorders. However, there is little guidance for conducting reproducible analyses or selecting appropriate effect sizes in small-N studies, which has implications for scientific review, rigor, and replication. This tutorial aims to (a) demonstrate how to conduct reproducible analyses using effect sizes common to research in aphasia and related disorders and (b) provide a conceptual discussion to improve the reader's understanding of these effect sizes. METHOD: We provide a tutorial on reproducible analyses of small-N designs in the statistical programming language R using published data from Wambaugh et al. (2017). In addition, we discuss the strengths, weaknesses, reporting requirements, and impact of experimental design decisions on effect sizes common to this body of research. RESULTS: Reproducible code demonstrates implementation and comparison of within-case standardized mean difference, proportion of maximal gain, tau-U, and frequentist and Bayesian mixed-effects models. Data, code, and an interactive web application are available as a resource for researchers, clinicians, and students. CONCLUSIONS: Pursuing reproducible research is key to promoting transparency in small-N treatment research. Researchers and clinicians must understand the properties of common effect size measures to make informed decisions in order to select ideal effect size measures and act as informed consumers of small-N studies. Together, a commitment to reproducibility and a keen understanding of effect sizes can improve the scientific rigor and synthesis of the evidence supporting clinical services in aphasiology and in communication sciences and disorders more broadly. Supplemental Material and Open Science Form: https://doi.org/10.23641/asha.21699476.


Asunto(s)
Afasia , Humanos , Reproducibilidad de los Resultados , Teorema de Bayes , Afasia/terapia , Comunicación , Estudiantes
15.
Int J Lang Commun Disord ; 58(3): 826-847, 2023 05.
Artículo en Inglés | MEDLINE | ID: mdl-36448625

RESUMEN

BACKGROUND: Little is known about story retelling and comprehension abilities in groups with lower levels of education and socio-economic status (SES). A growing body of evidence suggests the role of an extended network supporting narrative comprehension, but few studies have been conducted in clinical populations, even less in developing countries. AIMS: To extend our knowledge of the impact of a stroke on macrostructural aspects of discourse processes, namely main and complementary information, in individuals with middle-low to low SES and low levels of education. Relationships were tested between the performance in story retell and comprehension and reading and writing habits (RWH). Also, the associations between retelling and comprehension measures and their structural grey matter (GM) correlates were explored. METHODS & PROCEDURES: A total of 17 adults with unilateral left hemisphere (LH) chronic ischaemic stroke without the presence of significant aphasia and 10 matched (age, education and SES) healthy controls (HC) participated in the study. Retell and comprehension tasks were performed after listening or reading narrative stories. Voxel-based morphometry (VBM) analysis was conducted on a subgroup of nine individuals with LH stroke and the 10 matched controls using structural magnetic resonance imaging (MRI). OUTCOMES & RESULTS: Retelling and comprehension abilities were not significantly different between LH and HC, nonetheless quantitively lower in LH. Exploratory correlations showed that retelling and comprehension abilities in both written and auditory modalities were correlated with naming abilities. At the neural level, written comprehension positively correlated with GM density of the LH, including areas in the temporal pole, superior and middle temporal gyrus as well as the orbitofrontal cortex, precentral and postcentral gyri. Auditory narrative comprehension was associated with GM density of the lingual gyrus in the right hemisphere. CONCLUSIONS & IMPLICATIONS: The present results suggest that retelling and comprehension of auditory and written narratives are relatively well-preserved in individuals with a LH stroke without significant aphasia, but poorer than in HC. The findings replicate previous studies conducted in groups with higher levels of education and SES both at the behavioural and neural levels. Considering that naming seems to be associated with narrative retell and comprehension in individuals with lower SES and education, this research provides evidence on the importance of pursuing further studies including larger samples with and without aphasia as well as with various SES and education levels. WHAT THIS PAPER ADDS: What is already known on this subject Story retell and comprehension of auditory and written discourse have been shown to be affected after stroke, but most studies have been conducted on individuals with middle to high SES and high educational levels. What this paper adds to existing knowledge The study reports on narrative retell and comprehension in both auditory and written modalities in groups of HC and individuals with LH brain damage, with low-to-middle SES and lower levels of education. What are the potential or actual clinical implications of this work? This study highlights the importance of taking into consideration the sociodemographic and RWH of patients when assessing discourse retell and comprehension in both auditory and written modalities. It also underlines the importance of including patients without significant aphasia following LH stroke to look at the effect of both stroke and aphasia on narrative comprehension and story retelling.


Asunto(s)
Afasia , Isquemia Encefálica , Accidente Cerebrovascular , Adulto , Humanos , Accidente Cerebrovascular/complicaciones , Isquemia Encefálica/complicaciones , Afasia/etiología , Comprensión , Imagen por Resonancia Magnética
16.
Rev. chil. fonoaudiol. (En línea) ; 22(1): 1-13, 2023. ilus, tab
Artículo en Español | LILACS | ID: biblio-1444990

RESUMEN

La afasia como secuela de un accidente cerebrovascular es un trastorno del lenguaje poco estudiado en adolescentes, tanto en Latinoamérica como a nivel mundial. Independientemente del hecho de que un número significativo de afasias mejora espontáneamente, la necesidad del inicio oportuno del tratamiento es imprescindible. En esta serie de casos se describe la presentación clínica y evolución de la afasia en 3 adolescentes con secuelas de accidente cerebrovascular que ingresaron a un instituto de neurorehabilitación. Fueron dos mujeres y un varón, de entre 15 y 17 años, que recibieron rehabilitación integral intensiva desde las áreas de fisioterapia, terapia ocupacional, neuropsicología, psicopedagogía, musicoterapia y fonoaudiología. Fueron evaluados con la versión chilena de la herramienta Western Aphasia Battery (WAB). A los 3 meses todos mejoraron y evolucionaron a un tipo de afasia más leve. Este estudio expone la importancia del tratamiento precoz e intensivo en esta población de adolescentes en plena etapa de construcción social como personas, en donde la alteración del lenguaje impacta en sus vínculos, grupo de pertenencia, estado anímico y a nivel académico. Se considera fundamental la evaluación y seguimiento sistemático con el objetivo de identificar los cambios y avances alcanzados durante la rehabilitación.


Aphasia as a sequela of stroke is an understudied language disorder in adolescents, both in Latin America and worldwide. Although a significant number of aphasia cases improve spontaneously, it is necessary to initiate treatment as soon as possible. This cases series describes the clinical presentation and evolution of aphasia in 3 adolescents with stroke sequelae who were admitted to a neurorehabilitation facility. Two females and one male, aged between 15 and 17 years, received intensive comprehensive rehabilitation from the areas of physiotherapy, occupational therapy, neuropsychology, psychopedagogy, music therapy and speech therapy. They were evaluated with the Chilean version of the Western Aphasia Battery (WAB). After 3 months, all of them improved and evolved to a milder type of aphasia. This study shows the importance of early, intensive treatment in adolescents who are in the height of their social development, where language alteration impacts on their bonds, their groups of belonging, their mood and their academic process. Systematicassessment and follow-up are considered essential to identify the changes and progress achieved during rehabilitation.


Asunto(s)
Humanos , Masculino , Femenino , Adolescente , Afasia/fisiopatología , Afasia/rehabilitación , Accidente Cerebrovascular/complicaciones , Fonoaudiología , Rehabilitación Neurológica
17.
Audiol., Commun. res ; 28: e2745, 2023. graf
Artículo en Portugués | LILACS | ID: biblio-1420262

RESUMEN

RESUMO Objetivo observar, na linguagem em afasia de sujeitos adultos, a constituição de sentidos, considerando a (re)organização enunciativa na leitura e na escrita. Métodos pesquisa qualitativa com método aplicado e exploratório e perspectiva de análise enunciativa sobre a linguagem, tendo as noções de forma e sentido como base analítica. Foi realizada uma atividade com três sujeitos com afasia (Bir, Cr e Aul), integrantes do Grupo Interdisciplinar de Convivência (GIC), formado por participantes com e sem afasia. Tal atividade consistiu em (re)organizar quadrinhos de uma história, visando constituir sentido, uma vez que a leitura/escrita de textos são habilidades comumente comprometidas nas afasias. Resultados a categoria de tempo crônico mostra-se fundante para elaboração das narrativas dos sujeitos com afasia. Entretanto, eles encontraram formas distintas de sustentação de sentidos, mas sempre atrelados a experiências provenientes da relação entre homem e mundo. Conclusão as narrativas foram organizadas/construídas pelos participantes, tendo por base as imagens (base formal) - uma vez comprometida a habilidade de leitura de textos verbais. Bir, Cr e Aul usaram o tempo crônico como eixo organizacional de suas narrativas e suas histórias em quadrinhos, demonstrando que promovem leitura e escrita ao se considerar o viés enunciativo de análise da linguagem.


ABSTRACT Purpose to observe , in the language of aphasic adult subjects, the constitution of meanings, considering the enunciative (re)organization in reading and writing. Methods qualitative research with applied and exploratory methods and a perspective of enunciative analysis on language, using the notions of form and meaning as analytical base. From an activity performed by three subjects with aphasia (Bir, Cr and Aul), members of the Interdisciplinary Coexistence Group (GIC), formed by participants with and without aphasia, which constituted of (re)organizing the panels (frames) of a comic strip, in order to constitute meaning - since the reading/writing of texts are skills that are commonly affected in aphasia. Results the chronic time category shows itself to be fundamental for the elaboration of the narratives of the subjects with aphasia, however they found different ways of sustaining meanings, but always linked to experiences arising from the relationship between man and world. Conclusion the narratives were organized/constructed by the participants, having the images as a base (formal base) - since the ability to read verbal texts is impaired. Bir, Cr and Aul used chronic time as an organizational axis of their narratives and their comic strips show that these subjects with aphasia promote reading and writing when considering enunciative bias of language analysis.


Asunto(s)
Humanos , Afasia/terapia , Semántica , Trastornos del Habla , Historietas como Asunto
18.
Audiol., Commun. res ; 28: e2713, 2023. tab, graf
Artículo en Portugués | LILACS | ID: biblio-1420267

RESUMEN

RESUMO Objetivo Analisar a interlocução terapeuta-sujeito com afasia no processo de interpretação e organização de história em quadrinhos. Métodos Estudo transversal, de natureza qualitativa. Os dados coletados foram de situações enunciativas audiogravadas e apresentadas descritivamente por quadros de interlocução (A1-T1) e (A2-T2), registrando atividade com Histórias em Quadrinhos (HQ), realizada em encontro do Grupo Interdisciplinar de Convivência da instituição, do qual participaram sujeitos com e sem afasia. Analisou-se a interlocução entre duas terapeutas em formação (T1 e T2) e dois sujeitos com afasia (A1 e A2). Resultados As interlocuções entre A1-T1 e A2-T2, ocorridas durante o processo de organização das HQ, evidenciaram posicionamentos diferentes das terapeutas, no que tange ao ouvido e ao narrado. A1 foi reconhecida por T1 como sujeito de linguagem, à medida que a terapeuta promoveu a disjunção, ou seja, encaminhou A1 à condição de locutor; o mesmo fato não ocorreu com A2 e T2, pois o primeiro não foi reconhecido como sujeito de linguagem, já que T2 manteve-se em conjunção, não conferindo lugar de fala a A2. Conclusão A enunciação benvenistiana configura-se como recurso teórico-metodológico para análise e intervenção clínica junto a sujeitos com afasia. O contexto de convivência grupal impõe-se como lócus de cuidado e formativo para as diferentes áreas de atenção às pessoas com afasia, articulando, interdisciplinarmente, aspectos da enunciação à prática terapêutica.


ABSTRACT Purpose To analyze the therapist-subject with aphasia interlocution in the process of interpretation and organization of comics. Methods Cross-sectional study of a qualitative nature. The data are from audio-recorded enunciative situations and presented descriptively by interlocution charts (A1-T1) and (A2-T2), registering activity with Comics, held at a meeting of the Interdisciplinary Group of Coexistence (GIC) in which subjects with and without aphasia participate. The interlocution between two therapists in training (T1 and T2) and two subjects with aphasia (A1 and A2) is analyzed. Results: The interlocutions between A1-T1 and A2-T2, which occurred during the process of organization of the comic, show different positions of the therapists regarding the ear and the narrated. A1 is recognized by T1 as a subject of language as the therapist promotes disjunction, that is, it directs A1 to the condition of speaker; the same does not occur with A2 and T2, because the former is not recognized as a subject of language, since T2 remains in conjunction, not giving A2 speaking space. Conclusion Benvenistian enunciation is configured as a theoretical and methodological resource for analysis and clinical intervention with subjects with aphasia; the context of group coexistence imposes itself as a locus of care and training for the different areas of attention to people with aphasia, articulating, interdisciplinary, aspects of enunciation to therapeutic practice.


Asunto(s)
Humanos , Afasia/terapia , Trastornos del Habla , Historietas como Asunto , Estudios del Lenguaje , Estudios de Casos y Controles
19.
Artículo en Portugués | LILACS, CONASS, Coleciona SUS, SES-GO | ID: biblio-1444113

RESUMEN

Caracterizar as alterações de linguagem encontradas em pacientes com lesão encefálica adquirida em fase aguda Métodos: Trata-se de uma pesquisa observacional, descritiva do tipo transversal. A avaliação foi realizada nas enfermarias de um hospital de urgências, com pacientes de idade superior a 18 anos, diagnóstico de lesão encefálica adquirida e tempo de internação de até 60 dias. O protocolo utilizado incluiu avaliação das praxias orais, expressão, compreensão da linguagem oral e leitura. Ao final, foi possível apresentar as hipóteses diagnósticas de afasias fluentes e não fluentes, disartria e sem alteração de linguagem. A análise dos dados foi realizada por meio de estatística descritiva através da distribuição de frequência absoluta e frequência relativa Resultados: A amostra foi composta por 24 pacientes sendo a maioria do gênero masculino, com média de idade de 51 anos. O diagnóstico de maior frequência foi Acidente Vascular Cerebral. Dos pacientes avaliados, 79% tiveram alterações de fala/linguagem. As hipóteses diagnósticas fonoaudiológicas encontradas foram: afasia global, afasia de broca, afasia transcortical mista, afasia de condução, afasia transcortical motora, afasia transcortical sensorial e disartria. Conclusão: A afasia global foi o transtorno de linguagem de maior ocorrência entre os indivíduos, bem como o gênero masculino e o acidente vascular cerebral. A avaliação da linguagem de pacientes com lesões encefálicas adquiridas na fase aguda é pertinente, pois promove o levantamento de alterações desde as perceptíveis até as mais discretas


To characterize the language disorders found in patients with brain injury acquired in the acute phase Methods: This is an observational, descriptive cross-sectional study. The evaluation was carried out in the wards of an emergency hospital, with patients aged over 18 years, diagnosed with acquired brain injury and hospitalization time of up to 60 days. The protocol used included assessment of oral praxis, expression, comprehension of oral language and reading. In the end, it was possible to present the diagnostic hypotheses of fluent and non-fluent aphasias, dysarthria and without language alteration. Data analysis was performed using descriptive statistics through the distribution of absolute frequency and relative frequency. Results: The sample consisted of 24 patients, most of whom were male, with a mean age of 51 years. The most frequent diagnosis was Cerebral Vascular Accident. Of the evaluated patients, 79% had speech/language disorders. The speech-language diagnostic hypotheses found were: global aphasia, drill aphasia, mixed transcortical aphasia, conduction aphasia, motor transcortical aphasia, sensory transcortical aphasia and dysarthria. Conclusion: Global aphasia was the most frequent language disorder among individuals, as well as males and stroke. The evaluation of the language of patients with brain injuries acquired in the acute phase is relevant, as it promotes the survey of changes from the perceptible to the most discreet


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano , Adulto Joven , Lesiones Encefálicas/complicaciones , Accidente Cerebrovascular/complicaciones , Trastornos del Lenguaje , Afasia/diagnóstico , Disartria
20.
Artículo en Portugués | LILACS, CONASS, Coleciona SUS, SES-GO | ID: biblio-1561006

RESUMEN

Cerca de um terço da população acometida por Acidente Vascular Cerebral (AVC) pode desencadear afasia, sendo esta caracterizada pela perda ou comprometimento da função de linguagem, podendo causar prejuízos na compreensão, emissão da fala, habilidades de leitura, escrita e numéricas, considerada um preditor importante de sofrimento emocional e qualidade de vida (QV) negativa. O objetivo proposto de avaliar aspectos da QV de pacientes afásicos pós AVC.Trata-se de um estudo quantitativo, observacional, analítico e transversal realizado em um centro de reabilitação. Os critérios de inclusão foram idade acima de 18 anos, de ambos os sexos e excluídos pacientes com tempo de lesão menor que 6 meses, com história pregressa de doenças psiquiátricas e/ou condições neurológicas progressivas concomitantes. Foram coletados os dados sociodemográficos, as variáveis clínicas e aplicado o questionário SAQOL-39. Para análise estatística foi considerado o nível de 5% de significância. Resultados: Dos 33 participantes, 54,5% eram do sexo feminino, com prevalência de idade de 28 a 49 anos (45,5%), majoritariamente indivíduos casados (54,5%), tendo o cônjuge como o principal cuidador (58,1%). O domínio mais afetado foi o da comunicação (2,23) e o energia (3,15) o menos afetado. Foi observado relevância significativa entre QV e faixa etária, sexo, tipo de AVC, o não uso de cadeira de rodas e alterações motoras. Entre as diversas sequelas provenientes do AVC em afásicos, que influenciam diretamente no bem-estar geral, a comunicação parece ser a habilidade que mais impacta na QV destes indivíduos


About a third of the population affected by Cerebral Vascular Accident (CVA) can trigger aphasia, which is characterized by the loss or impairment of the language function, which can cause impairments in comprehension, speech emission, reading, writing and numerical skills, considered a important predictor of emotional distress and negative quality of life (QoL). Objective: Evaluate QoL aspects of aphasic patients after stroke. Method: Quantitative, observational, analytical and cross-sectional study carried out in a rehabilitation center. Inclusion criteria were age above 18 years, of both genders, and patients with injury time of less than 6 months, with a past history of psychiatric illnesses and/or concomitant progressive neurological conditions were excluded. Sociodemographic data and clinical variables were collected and the SAQOL-39 questionnaire was applied. For statistical analysis, a significance level of 5% was considered. Results: Of the 33 participants, 54.5% were female, with an age prevalence of 28 to 49 years (45.5%), mostly married individuals (54.5%), with the spouse as the main caregiver (58.1 %). The most affected domain was communication (2.23) and energy (3.15) the least affected. Significant relevance was observed between QoL and age group, sex, type of stroke, non-use of a wheelchair and motor alterations. Conclusion: Among the various sequelae from stroke in aphasic patients, which directly influence general well-being, communication seems to be the skill that most impacts the QoL of these individuals


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano , Afasia , Calidad de Vida , Accidente Cerebrovascular/complicaciones , Brasil
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