RESUMEN

BACKGROUND: Hernia correction is a routinely performed treatment in surgical practice. The improvement of the operative technique and available materials certainly has been a great benefit to the quality of surgical results. The insertion of prostheses for hernia correction is well-founded in the literature, and has become the standard of treatment when this type of disease is discussed. AIM: To evaluate two available prostheses: the polypropylene and polypropylene coated ones in an experimental model. METHODS: Seven prostheses of each kind were inserted into Wistar rats (Ratus norvegicus albinus) in the anterior abdominal wall of the animal in direct contact with the viscera. After 90 days follow-up were analyzed the intra-abdominal adhesions, and also performed immunohistochemical evaluation and videomorphometry of the total, type I and type III collagen. Histological analysis was also performed with hematoxylin-eosin to evaluate cell types present in each mesh. RESULTS: At 90 days the adhesions were not different among the groups (p=0.335). Total collagen likewise was not statistically different (p=0.810). Statistically there was more type III collagen in the coated polypropylene group (p=0.039) while type I was not different among the prostheses (p=0.050). The lymphocytes were statistically more present in the polypropylene group (p=0.041). CONCLUSION: The coated prosthesis was not different from the polypropylene one regarding the adhesion. Total and type I collagen were not different among the groups, while type III collagen was more present on the coated mesh. There was a greater number of lymphocytes on the polypropylene mesh.

Asunto(s)

RESUMEN

ABSTRACT Background: Hernia correction is a routinely performed treatment in surgical practice. The improvement of the operative technique and available materials certainly has been a great benefit to the quality of surgical results. The insertion of prostheses for hernia correction is well-founded in the literature, and has become the standard of treatment when this type of disease is discussed. Aim: To evaluate two available prostheses: the polypropylene and polypropylene coated ones in an experimental model. Methods: Seven prostheses of each kind were inserted into Wistar rats (Ratus norvegicus albinus) in the anterior abdominal wall of the animal in direct contact with the viscera. After 90 days follow-up were analyzed the intra-abdominal adhesions, and also performed immunohistochemical evaluation and videomorphometry of the total, type I and type III collagen. Histological analysis was also performed with hematoxylin-eosin to evaluate cell types present in each mesh. Results: At 90 days the adhesions were not different among the groups (p=0.335). Total collagen likewise was not statistically different (p=0.810). Statistically there was more type III collagen in the coated polypropylene group (p=0.039) while type I was not different among the prostheses (p=0.050). The lymphocytes were statistically more present in the polypropylene group (p=0.041). Conclusion: The coated prosthesis was not different from the polypropylene one regarding the adhesion. Total and type I collagen were not different among the groups, while type III collagen was more present on the coated mesh. There was a greater number of lymphocytes on the polypropylene mesh.

RESUMO Racional: A correção herniária é tratamento realizado rotineiramente na prática cirúrgica. O aprimoramento da técnica operatória e dos materiais disponíveis trouxe grande benefício na qualidade dos resultados cirúrgicos. A inserção de próteses para correção herniária é bem embasada na literatura e tornou-se o padrão de tratamento. Objetivo: Avaliar em modelo experimental dois tipos de próteses diferentes, de polipropileno e polipropileno revestido. Métodos: Foram inseridas sete próteses de cada tipo em ratos Wistar (Ratus norvegicus albinus) na parede abdominal anterior do animal em contato direto com as vísceras. Após o seguimento de 90 dias analisaram-se as aderências intra-abdominais, bem como avaliação por imunoistoquímica e videomorfometria do colágeno total, tipo I e tipo III. Também, fez-se análise histológica com hematoxylina-eosina para avaliação dos tipos celulares presentes em cada tela. Resultados: Aos 90 dias as aderências não foram diferentes entre os grupos (p=0,335). O colágeno total igualmente não foi estatisticamente diferente (p=0,810). O colágeno tipo III foi estatisticamente maior no grupo polipropileno revestido (p=0,039) enquanto o tipo I não diferiu entre as próteses (p=0,050). Os linfócitos foram estatisticamente mais presentes no grupo polipropileno (p=0,041). Conclusão: A prótese revestida não foi diferente da de polipropileno na variável aderência. O colágeno total e tipo I não foram diferentes entre os grupos enquanto que o colágeno tipo III foi mais presente na tela revestida. O número de linfócitos foi maior na tela de polipropileno.

Asunto(s)

RESUMEN

PURPOSE: To evaluate the effect of Schinus terebinthifolius Raddi (aroeira) and Orbignya phalerata Mart. (babassu) in the healing process of cecorrhaphy in rats. METHODS: : Fifty four rats were used, distributed into three groups randomly: aroeira, babassu and control, which were divided into three subgroups (six animals) according to the time of the deaths (7, 14, 21 days). All underwent the same surgical procedure, cecotomy and cecorrhaphy. The animals in group aroeira and babassu received daily dose of 100 mg/kg of hydroalcoholic extract and 50 mg/kg of aquous extract respectively, by gavage. The control group received only saline solution. The parameters evaluated were: macroscopic changes, ,resistance test to air insufflations and histological changes. RESULTS: : All animals showed good healing without infection. All groups presented adhesions between cecum and neighboring organs. The resistance test insufflating of atmospheric air showed progressive increase of pressure according to the days in the aroeira group, and decrease in babassu group, without significant difference. Microscopy showed significant difference in the polymorphonuclear, hyperemia, angiogenesis, fibroblast proliferation and collagen histological variables in the 14th day. CONCLUSION: : Hydroalcoholic extract of aroeira and the aqueous extract of babassu favored the healing process in cecorrhaphy in rats.

Asunto(s)

RESUMEN

El uso del Fumarato Ferroso Microencapsulado, produce una reducción significativa de la prevalencia de anemia en una población pediatrica de alto riesgo por presentar mejor adherencia a este. La aplicación de la nueva intervención en los Programas de Salud, aumentaria e n un 33 porciento los beneficio obtenidos por el nuevo suplemento, es decir que cada 3 niños tratados con Fumarato Ferroso, uno aumentará sus niveles de hemoglobina hasta alcanzar el estado no anémico...

Asunto(s)

RESUMEN

Os autores fazem uma revisão e atualização sobre as sinéquias intra-uterinas (SIUs), enfocando principalmente sua importância atual e o método histeroscópico para o tratamento dessa afecção. Outros enfoques terapêuticos como a histerotomia no tratamento das SIUs totais, limitações do método histeroscópico e eventuais complicações obstétricas subseqüentes à sinequiolise histeroscópica são também discutidos neste trabalho

Asunto(s)

RESUMEN

Se presenta una clasificación laparoscópica de las adherencias anexiales no endometriósicas, empleada en nuestro servicio y que consideramos de gran valor, pues se basa más en el análisis de la afección fisiológica posible, por parte del endoscopista, que en la lesión anatómica pura (tamaño y caracteres o localización de las adherencias). Se revisan las causas y los mecanismos de producción de estas adherencias y se insiste en su profilaxis (AU)

Asunto(s)

RESUMEN

Se presenta una clasificación laparoscópica de las adherencias anexiales no endometriósicas, empleada en nuestro servicio y que consideramos de gran valor, pues se basa más en el análisis de la afección fisiológica posible, por parte del endoscopista, que en la lesión anatómica pura (tamaño y caracteres o localización de las adherencias). Se revisan las causas y los mecanismos de producción de estas adherencias y se insiste en su profilaxis

Asunto(s)

RESUMEN

Se revisaron 200 pacientes estériles con factor tuboperitoneal alterado. La enfermedad adhesiva anexial fue el factor más importante en la esterilidad. La mayor parte de los casos estaban en la tercera década de vida; 40.5% fue de enfermedad inflamatoria pélvica inespecífica que respondió bien al tratamiento con antibióticos y antiinflamatorios. A mayor grado e enfermedad anexial adhesiva, menor posibilidad de embarazo

Asunto(s)