RESUMEN

The case of a 49 yr old alcoholic women with clinical and laboratory findings that suggested a Cushing syndrome is presented. The functional tests showed cortisol suppression greater than 50% of the basal value with 8 mg of dexamethasone and no response in the combined dexamethasone/desmopressin test. Pituitary Nuclear Magnetic Resonance (NMR) was negative, Abdominal Computed Axial Tomography suggested hyperplastic adrenal glands; adrenal nodules were not found in the NMR. Pituitary or hipothalamic Cushing with secondary autonomous micronodular adrenal hyperplasia was suspected. Norcholesterol-I131 SPECT scintigraphy under dexamethasone suppression demonstrated a functional adrenal hyperplasia which was hystologically confirmed.

Asunto(s)

19-Yodocolesterol/análogos & derivados , Corteza Suprarrenal/diagnóstico por imagen , Síndrome de Cushing/diagnóstico por imagen , Glándulas Suprarrenales , Síndrome de Cushing/etiología , Femenino , Humanos , Persona de Mediana Edad , Hipófisis , Tomografía Computarizada de Emisión de Fotón Único