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Introduction: Urinary incontinence (UI) is highly prevalent in low- and middle-income countries (LMIC). Concurrently, the availability of surgical or conservative UI treatments in LMIC is limited. Methods: We conducted a prospective feasibility study of Belize women with UI treated with pelvic floor physical therapy (PFPT) and education (PFE). Patients received individual PFPT/PFE over 2 days, consisting of biofeedback-enhanced PFMT in addition to behavioral, dietary, and general pelvic education. Patient completed a daily 6-month home regimen including 7 PFMT exercises (total 70 repetitions) comprising both endurance and quick flick exercises. Patients also performed comprehensive dietary and behavioral modification activities. Outcomes were assessed at baseline and 6-months, including validated symptom (ICIQ-FLUTS) and QOL (IIQ-7) questionnaires, and strength testing (PERFECT score, perineometry). Results: Twenty-eight patients underwent baseline assessment. Four patients were lost to in-person 6-month follow-up, with two of these patients completing subjective assessment only by telephone. The mean (±SD) patient age, BMI, and parity were 50.0 (±10.0) years, 33.2 (±5.8), and 2.8 (±1.5). Provider assessment demonstrated patient comprehension of basic, endurance, and quick flick pelvic floor contractions in 28 (100%), 24 (86%), and 24 (86%) patients, respectively. At 6-month follow-up, significant improvements were seen across multiple validated questionnaire and strength measurement assessments. Median patient-reported improvement level was 7.0 on a 10-point Likert scale. Discussion: Study patients demonstrated good understanding of PFMT/PFE and program completion was associated with significant improvements across a variety of subjective incontinence and quality of life outcomes, as well as objective strength testing.
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BACKGROUND: Urinary incontinence (UI) is a common dysfunction of the pelvic floor, affecting 10-20% of all women, and up to 70% in the elderly general prevalence of 17% 20-year-old women and 38% in women over 60 years. It is estimated that only 25% of patients seek treatment for this debilitating condition. AIM: The aim of this study was to evaluate the efficacy of a device based on top flat magnetic stimulation to treat pelvic floor disorders especially female urinary incontinence. METHODS: A total of 33 volunteer patients were divided into 5 groups according to the type of complaint. Subjects received 8 treatment sessions, with a frequency of twice a week with two different settings. Pelvic Floor Bother Questionnaire (PFBQ), Pelvic Organ Prolapse/Urinary Incontinence Sexual Function Questionnaire (PISQ-12) and Urinary Incontinence Short Form (ICIQ-UI-SF) were compiled by all patients at the beginning and after 3 months from the end of the last treatment (3MFU). RESULTS: The patient's scores from validated Questionnaires significantly decreased (p < 0.01) from baseline up to 3MFU inside most of the groups. CONCLUSIONS: The noninvasiveness and safety of device make this approach an interesting tool as alternative approach for pelvic floor dysfunctions .
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Trastornos del Suelo Pélvico , Prolapso de Órgano Pélvico , Incontinencia Urinaria , Femenino , Humanos , Anciano , Adulto Joven , Adulto , Diafragma Pélvico , América Latina/epidemiología , Incontinencia Urinaria/terapia , Trastornos del Suelo Pélvico/complicaciones , Trastornos del Suelo Pélvico/terapia , Prolapso de Órgano Pélvico/complicaciones , Prolapso de Órgano Pélvico/terapia , Encuestas y Cuestionarios , Fenómenos Magnéticos , Calidad de VidaRESUMEN
INTRODUCTION AND HYPOTHESIS: Electrical nerve stimulation is a widely used treatment for overactive bladder but there is no consensus regarding the best placement of electrodes or protocols. We hypothesised that some non-implanted neurostimulation protocols would be more effective compared to others for treating urinary symptoms and improving quality of life among adults diagnosed with non-neurogenic overactive bladder. METHODS: A systematic review and meta-analyses of randomized clinical trials were performed in five electronic databases: PubMed/MEDLINE, Lilacs, CINAHL, Web of Science, and PEDro. The main outcome was urinary symptoms-frequency, nocturia, and urgency-and the secondary outcome quality of life. Some protocol characteristics were extracted, e.g., frequency, pulse width, intensity, intervention time, and electrode placement. RESULTS: Nine randomized controlled trials were included. Tibial neurostimulation showed better results than sacral neurostimulation for urge incontinence (mean difference = 1.25 episodes, 95% CI, 0.12-2.38, n = 73). On the pooled analysis, the different neurostimulation protocols-intravaginal, percutaneous tibial, and transcutaneous tibial nerve stimulation-demonstrated similar results for urinary frequency, nocturia, and urgency as well as quality of life. In general, effect sizes from meta-analyses were low to moderate. The best reported parameters for percutaneous tibial nerve stimulation were 20-Hz frequency and 200-µs width, once a week. CONCLUSIONS: There was evidence that tibial neurostimulation is more effective than sacral neurostimulation for urge incontinence symptoms among patients with non-neurogenic overactive bladder. Overall, there was no superiority of an electrical nerve stimulation electrode placement and protocol over others considering urinary symptoms and quality of life. Further studies with three-arm trials are necessary. This study was registered at PROSPERO: CRD4201810071.
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Nocturia , Estimulación Eléctrica Transcutánea del Nervio , Vejiga Urinaria Hiperactiva , Adulto , Humanos , Calidad de Vida , Nervio Tibial , Estimulación Eléctrica Transcutánea del Nervio/métodos , Resultado del Tratamiento , Vejiga Urinaria Hiperactiva/tratamiento farmacológico , Incontinencia Urinaria de Urgencia/terapiaRESUMEN
Abstract Introduction: Urinary incontinence (UI) is present in the lives of a considerable number of women worldwide. This condition and its associated factors have been sufficiently investigated in recent years, however, prevalence estimates are still not fully clarified, as UI is seen as stigmatizing in a cultural context, and the search for treatment is not always considered by affected individuals. So, this dysfunction and its subtypes must be better understood so that it is possible to alleviate its consequences. Objective: To identify the prevalence of urinary incontinence subtypes, in women from a reference clinic in a public hospital in Curitiba, PR, Brazil. Methods: This was an observational and analytical study, with 227 women affected by UI, evaluated by means of a questionnaire including sociodemographic and general health information, in addition to defining the UI subtype. The SPSS version 25 was used for statistical analysis. Results: The patients presented a mean age of 60.33 ± 12.26 years. Mixed UI was the prevalent subtype (87.2%; n = 198), followed by stress (7.5%; n = 17), and urge (5.3%; n = 12). Among women with mixed UI, 60.6% had only completed elementary school, 59.1% were housewives, and 87.6% had experienced two or more pregnancies. Conclusion: Outlining UI subtypes, and the general and obstetric characteristics of the studied population enables the development of coping strategies for this condition, ranging from planning, diagnosis and treatment, to costs and public health management.
Resumo Introdução: A incontinência urinária (IU) está presente na vida de considerável número de mulheres no mundo. Essa condição e fatores associados a ela vêm sendo suficientemente investigados nos últimos anos, no entanto, as estimativas de prevalência ainda não são totalmente esclarecidas visto que a IU é vista como estigmatizante em âmbito cultural e a procura por tratamento nem sempre é considerada por indivíduos acometidos. Torna-se importante, portanto, esclarecer cada vez mais essa disfunção e seus subtipos para que seja possível amenizar suas consequências. Objetivo: Identificar a prevalência dos subtipos de IU em mulheres de um ambulatório de referência em um hospital público de Curitiba, PR. Métodos: Estudo observacional e analítico com 227 mulheres com IU, avaliadas por meio de um questionário para coleta de informações sociodemográficas e de saúde geral, além da definição do subtipo de IU. Utilizou-se o pacote estatístico SPSS versão 25 para a análise estatística. Resultados: A idade média da amostra foi de 60,33 ± 12,26 anos. IU mista foi o subtipo mais prevalente (87,2%; n = 198), seguida por esforço (7,5%; n = 17) e urgência (5,3%; n = 12). Das mulheres com IU mista, 60,6% tinham apenas o ensino fundamental, 59,1% eram donas de casa e 89,4% passaram por duas ou mais gestações. Conclusão: Delinear os subtipos de IU e as características gerais e obstétricas da população estudada permite que sejam elaboradas estratégias de enfrentamento desta condição, que vão desde planejamento envolvendo diagnóstico e tratamento até custos e gestão de saúde pública.
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A bexiga hiperativa caracteriza-se pela urgência miccional, geralmente acompa- nhada de noctúria e aumento da frequência urinária. Trata-se de afecção preva- lente, com enorme comprometimento da qualidade de vida, em todos os seus as- pectos. Diversos biomarcadores vêm sendo estudados para melhor caracterização dos diferentes fenótipos da afecção, entre eles as neurotrofinas urinárias, o ATP, a genômica e a microbiota urinária. Acredita-se que tal caracterização poderá ter implicações para prevenção, fisiopatologia e individualização do tratamento.(AU)
The overactive bladder is characterized by urinary urgency, usually accompanied by nocturia and increased urinary frequency. It is a prevalent condition, with enormous impairment of quality of life, in all its aspects. Several biomarkers have been studied to better characterize the different phenotypes of the condition, including urinary neurotrophins, ATP, genomics and urinary microbiota. It is believed that such charac- terization may have implications for prevention, pathophysiology and individualiza- tion of treatment.(AU)
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Humanos , Masculino , Femenino , Vejiga Urinaria Hiperactiva , Incontinencia Urinaria de Urgencia , Biomarcadores , Adenosina Trifosfato , Genómica , Microbiota , Factores de Crecimiento NerviosoRESUMEN
OBJECTIVES: The Brazilian public health system does not cover pharmacotherapy for urge urinary incontinence (UUI). The aim of this study was to estimate the cost-effectiveness and budget impact of providing tolterodine, solifenacin, oxybutynin (OXY), darifenacin, and mirabegron for the treatment of UUI in Brazilian public health system. METHODS: A cost-effectiveness analysis with budget impact was performed. Six scenarios were assessed: in one scenario, all 5 therapeutic alternatives approved for coverage, and in the remaining 5 scenarios, only 1 alternative is approved for adoption for all patients. Clinical data were derived from a rapid systematic review conducted in several databases. One-way sensitivity analysis was also performed. The time horizon was 12 months. RESULTS: The cost-effectiveness analysis showed that patients treated with OXY had the lowest incremental cost-effectiveness ratio (ICER) per outcomes assessed (change in urinary incontinence episodes (UIE): R$1180.08; change in urge incontinence episodes: R$757.85 and change in micturition frequency: R$907.75), corresponding to a budget impact of R$17.9 billion over 5 years. The change in effectiveness measures was the parameter that most influenced the results of the ICER per patient-year. CONCLUSION: The results of the study have shown that OXY and solifenacin had the lowest ICER per patient-year and the lowest budget impact when compared with other drugs.
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Acetanilidas/economía , Antagonistas Muscarínicos/economía , Salud Pública/tendencias , Tiazoles/economía , Incontinencia Urinaria de Urgencia/tratamiento farmacológico , Acetanilidas/uso terapéutico , Adulto , Brasil , Análisis Costo-Beneficio/métodos , Análisis Costo-Beneficio/estadística & datos numéricos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Antagonistas Muscarínicos/uso terapéutico , Salud Pública/economía , Salud Pública/estadística & datos numéricos , Tiazoles/uso terapéutico , Incontinencia Urinaria de Urgencia/economía , Agentes Urológicos/economía , Agentes Urológicos/uso terapéuticoRESUMEN
RESUMO Objetivo: verificar fatores associados a incontinência urinária em mulheres por tipo e gravidade. Metodologia: estudo transversal, realizado de novembro de 2018 a abril de 2019, com 30 mulheres em um hospital escola de Pernambuco. Foi utilizado o instrumento Gaudenz-Fragebogen para identificar os tipos de incontinência e o Incontinence Severity Index para classificar a gravidade da perda urinária. Utilizou-se o teste Exato de Fisher para analisar variáveis qualitativas e t-Student para variáveis racionais Resultados: incontinência urinária de esforço foi o tipo mais frequente (66,7%), na forma moderada (43,3%) e esteve associada a baixa escolaridade (p<0,001), índice de massa corporal de 28,6 (p=0,043), circunferência abdominal de 103,4 (p<0,001), diabetes (p<0,001), número de partos superior a 4 (p=0,046), cirurgia ginecológica (p=0,023) e falta de atividade física (p=0,001). Considerações Finais: a identificação do tipo, da gravidade e dos principais fatores de risco modificáveis poderá subsidiar intervenções preventivas e curativas mais eficientes e efetivas.
RESUMEN: Objetivo: verificar factores asociados con la incontinencia urinaria en mujeres, por tipo y por gravedad. Metodología: estudio transversal realizado entre noviembre de 2018 y abril de 2019 con 30 mujeres en un hospital escuela de Pernambuco. Se utilizó el instrumento Gaudenz- Fragebogen para identificar los tipos de incontinencia y el Incontinence Severity Index para clasificar la gravedad de la pérdida de orina. Se utilizó la prueba exacta de Fisher para analizar las variables cualitativas, y el t-Student para las variables racionales. Resultados: la incontinencia urinaria por esfuerzo fue el tipo más frecuente (66,7%), en su forma moderada (43,3%) y estuvo asociada a un bajo nivel de escolaridad (p<0,001), a un Índice de Masa Corporal de 28,6 (p=0,043), a una circunferencia abdominal de 103,4 (p<0,001), diabetes (p<0,001), cantidad de partos superior a 4 (p=0,046), cirugía ginecológica (p=0,023) y a la falta de actividad física (p=0,001). Consideraciones finales: identificar el tipo, la gravedad y los principales factores de riesgo modificables podrá ayudar a diseñar intervenciones preventivas y curativas más eficientes y efectivas.
ABSTRACT Objective: To verify factors associated with urinary incontinence in women by type and severity. Methodology: A cross-sectional study conducted from November 2018 to April 2019 with 30 women in a teaching hospital of Pernambuco. The Gaudenz-Fragebogen instrument was used to identify incontinence types, and the Incontinence Severity Index to classify urinary loss severity. Fisher's exact test was used to analyze qualitative variables, and the t-Student test for rational variables. Results: Stress-induced urinary incontinence was the most frequent type (66.7%), in its moderate form (43.3%), and was associated with low schooling (p<0.001), Body Mass Index of 28.6 (p=0.043), abdominal circumference of 103.4 (p<0.001), diabetes (p<0.001), number of deliveries above 4 (p=0.046), gynecological surgery (p=0.023), and lack of physical activity (p=0.001). Final Considerations: Identifying the type, severity, and main modifiable risk factors may support more effective and efficient preventive and curative interventions.
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OBJECTIVE: To analyze via the Andersen model what leads women with urinary incontinence (UI) to seek help and remain in the healthcare system. METHODS: An interpretative phenomenologic study enrolling women aged 18 years or older who were diagnosed with UI at a tertiary care hospital in Chile between January and March 2016. Data were collected by semi-structured interview. The categories explored experience with UI and reasons for seeking health care, and included the dimensions of the Andersen model. RESULTS: Ten women were enrolled. Characteristics that eased or hindered healthcare seeking were identified to come from the women (frequency and quantity of symptoms, coping strategies, and beliefs about its causes) and from their environment (reaction of partner, family, or coworkers to her condition). Some were associated with primary care (human and/or technical resources) and some with secondary care (pelvic floor units). CONCLUSION: The results reflect the complexities of asking for health care for women with UI, especially in a country such as Chile with different healthcare levels. Raising awareness of this complexity and developing an approach that includes all stakeholders (institution, community, and family) is crucial for professionals who want to offer both medical therapy and wellness-focused healthcare.
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Conocimientos, Actitudes y Práctica en Salud , Conducta de Búsqueda de Ayuda , Aceptación de la Atención de Salud/estadística & datos numéricos , Incontinencia Urinaria/psicología , Adaptación Psicológica , Adulto , Chile , Femenino , Humanos , Entrevistas como Asunto , Persona de Mediana Edad , Calidad de Vida , Incontinencia Urinaria/terapia , Adulto JovenRESUMEN
AIMS: To compare 300 U versus 500 U of abobotulinumtoxinA (ABO) intravesical injections for the treatment of idiopathic overactive bladder (OAB) refractory to first and second-line treatments. METHODS: A prospective, randomized, single blind study was performed in female patients with symptoms of OAB, who had failed conservative treatment. Patients were treated with 300 or 500 U of ABO injected into 30 sites, avoiding the trigone. All treatments were evaluated by voiding diary, ICIQ-OAB questionnaire, urodynamic test, visual analogue scale (VAS) for treatment satisfaction and patient global impression of improvement (PGI-I). The primary outcome was change in maximum cistometric capacity (MCC). Secondary outcome included changes in urgency, complete continence, subjective success (VAS and PGI-I), and adverse events (urinary retention, UTI, and CIC). RESULTS: Twenty-one patients were included. MCC has increased from 185.0 to 270.9 mL (300 U) and from 240.8 to 311.7 mL (500 U), comparing the baseline with 12 weeks, without statistical difference between the groups (P = 0.270). At 12 weeks, 91% of patients were dry in both groups. At 24 weeks, episodes of incontinence had returned in 50% (300 U) and 0% (500 U) (P = 0.013). Patients were better or much better (PGI-I) in70% (300 U) and 88.9% (500 U) at 12 w; and 50% (300 U) and 100% (500 U), at 24 w (P = 0.027). The peak of PVR was at 4 w, being 71.7 mL (300 U) and 96.5 mL (500 U). General UTI incidence was 35.7%. One patient (500 U) required CIC for 2 weeks. CONCLUSIONS: Intravesical ABO injection at 500 U improves symptoms and quality of life for longer period of time than 300 U for idiopathic OAB.
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Toxinas Botulínicas Tipo A/uso terapéutico , Vejiga Urinaria Hiperactiva/tratamiento farmacológico , Micción/efectos de los fármacos , Urodinámica/efectos de los fármacos , Agentes Urológicos/uso terapéutico , Administración Intravesical , Adulto , Anciano , Toxinas Botulínicas Tipo A/administración & dosificación , Femenino , Humanos , Persona de Mediana Edad , Satisfacción del Paciente , Estudios Prospectivos , Calidad de Vida , Método Simple Ciego , Encuestas y Cuestionarios , Resultado del Tratamiento , Agentes Urológicos/administración & dosificación , Escala Visual AnalógicaRESUMEN
INTRODUCTION AND HYPOTHESIS: Our objective was to evaluate the effectiveness of pelvic floor muscle training (PFMT) in reducing overactive bladder (OAB) symptoms in women. METHODS: Searches were performed at MEDLINE, PubMed, Physiotherapy Evidence Database (PEDro), Scielo, and Central Cochrane Library PubMed until January 2017. Controlled trials were researched by two independent reviewers. Eligible studies were restricted to random and controlled clinical trials that investigated the effectiveness of PFMT in decreasing OAB symptoms. Qualitative methodology was evaluated using the PEDro scale. Data was analyzed and interpreted qualitatively. RESULTS: The final search retrieved eight studies (n = 1161 women with urgency symptoms), which were published between 2002 and 2016. The methodological scores varied between 4 and 7 in the PEDro scale. PFMT, with the objective of controlling urgent micturition, demonstrated improvements in quality of life in women with OAB. Most data in this revision came from small- to moderate-sized trials, with different and inconsistent outcome measures, which could have impacted the end results. CONCLUSIONS: The literature regarding the effectiveness of PFMT in OAB remains heterogeneous and inconclusive.
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Terapia por Ejercicio/métodos , Modalidades de Fisioterapia , Vejiga Urinaria Hiperactiva/terapia , Adulto , Femenino , Humanos , Persona de Mediana Edad , Diafragma Pélvico/fisiopatología , Síndrome , Resultado del Tratamiento , Vejiga Urinaria Hiperactiva/fisiopatologíaRESUMEN
AIM: Depression and anxiety are prevalent psychiatric conditions and are associated with overactive bladder. The objective of this study was to determine prevalence and severity of anxiety and depression associated with overactive bladder (OAB) in women. METHODS: 274 women with clinical diagnosis of OAB were recruited from 2012 to 2015. They were submitted to the International Consultation on Incontinence Questionnaire-Overactive Bladder (ICIQ-OAB), the Beck Depression Inventory (BDI), and the Beck Anxiety Inventory (BAI). RESULTS: Severe or moderate depression was present in 59.8% of women and severe or moderate anxiety was identified in 62.4%. Higher scores of depression and anxiety were associated with higher scores of ICIQ-OAB (P = 0.0031 and 0.0049). Women with severe depression had higher nocturia score than those with mild depression (P = 0.0046). Also, women with severe depression had higher urgency incontinence score than those with minimal depression (P = 0.0261). Patients with severe anxiety had higher nocturia score than those with minimal anxiety (P = 0.0118) and women with moderate anxiety had higher urgency incontinence score than with minimal anxiety (P = 0.0300). CONCLUSIONS: Moderate or severe depression and anxiety are prevalent in women with OAB. There is a correlation between intensity of OAB symptoms with depression and anxiety. Anxiety and depression levels are mainly related with urgency incontinence and nocturia.
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Trastornos de Ansiedad/etiología , Trastornos de Ansiedad/psicología , Trastorno Depresivo/etiología , Trastorno Depresivo/psicología , Vejiga Urinaria Hiperactiva/complicaciones , Vejiga Urinaria Hiperactiva/psicología , Adulto , Anciano , Trastornos de Ansiedad/epidemiología , Brasil/epidemiología , Estudios Transversales , Trastorno Depresivo/epidemiología , Femenino , Humanos , Persona de Mediana Edad , Nocturia/epidemiología , Nocturia/psicología , Prevalencia , Escalas de Valoración Psiquiátrica , Factores Socioeconómicos , Encuestas y Cuestionarios , Vejiga Urinaria Hiperactiva/epidemiología , Incontinencia Urinaria/complicaciones , Incontinencia Urinaria/psicologíaRESUMEN
BACKGROUND AND AIMS: Models of tobacco smoking behaviour propose that anticipated pleasure or satisfaction, the need to alleviate a nicotine-induced drive state and a stimulus-driven impulse potentially play an important role. This study aimed to provide a preliminary assessment of how far urges to smoke are reported by smokers and whether the strength of such urges prior to a quit attempt predicts short-term success at quitting. METHODS: In a prospective study, 566 smokers attending a treatment programme to help smokers quit completed a written questionnaire covering frequency of different types of urge to smoke (automatic impulse - 'automatic urges', anticipated pleasure - 'pleasure urges', and fulfilling a need - 'need urges'). They were asked to rate this for whichever of these urges was dominant for them. The questionnaire also assessed daily cigarette consumption, time to first cigarette of the day, age and gender. Carbon monoxide verified smoking status was recorded at 1 and 4weeks after the target quit date. FINDINGS: A total of 47.9% (271) of smokers reported that automatic urges were dominant, 21.7% (123) reported pleasure urges to be dominant, and 30.4% (172) reported need urges to be dominant. The strength of automatic urges predicted abstinence at both 1week (OR=0.74, p=0.005, 95%CI=0.60-0.92) and 4weeks (OR=0.73, p=0.008, 95%CI=0.59-0.92). Associations between other urge types and abstinence were not statistically significant. CONCLUSIONS: A substantial proportion of smokers attending a clinic for help with quitting report that their dominant urges to smoke occur without any anticipation of pleasure or relief and the strength of the automatic urges predicts failure to sustain abstinence following a quit attempt.
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Fumar Cigarrillos/terapia , Impulso (Psicología) , Hábitos , Cese del Hábito de Fumar/psicología , Fumar/psicología , Argentina , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Cese del Hábito de Fumar/métodos , Cese del Hábito de Fumar/estadística & datos numéricos , Encuestas y CuestionariosRESUMEN
La colpocleisis como técnica obliterante se va realizando desde el año 1823 y se ofrece como alternativa para tratamiento quirúrgico de prolapso tipo III y IV a pacientes sin deseo de vida sexual y con riesgos de morbilidad transquirúrgica. No existe mucha evidencia del grado de satisfacción post-quirúrgica de las pacientes Objetivo: determinar el grado de satisfacción de las pacientes sometidas a colpocleisis y los síntomas pélvicos más frecuentemente encontrados a lo largo del primer año post- quirúrgico. Método: studio transversal no experimental. Se aplicó cuestionario validado de satisfacción post-quirúrgica en pacientes sometidas a colpocleisis durante periodos 2013 a 2014, vía telefónica, dentro de su primer año post-quirúrgico. Se tabularon los datos obtenidos. Resultados: El total de pacientes encuestadas se encontraban entre satisfechas y muy satisfechas e indicaban que volverían a someterse a la cirugía. La edad promedio de las pacientes fue de 76 años. El 50% de las pacientes presentaron incontinencia urinaria de urgencia, 15% incontinencia anal, el restante 35% no presentó ninguna sintomatología. Los síntomas pélvicos se presentaron con más frecuencia en las pacientes con prolapsos tipo IV. Conclusiones: el nivel de satisfacción delas pacientes sometidas a colpocleisis es alto, se puede seguir ofreciendo como alternativa quirúrgica en mujeres sin actividad sexual, la sintomatología pélvica más frecuente fue incontinencia urinaria de urgencia e incontinencia anal, en las pacientes con mayor grado de prolapso.
The colpocleisis as obliterans technique is conducted since 1823 and is offered as an alternative to surgical treatment of prolapse type III and IV patients with no sexual desire for life and morbidity risks transsurgical. There is much evidence of the degree of post-surgical patient satisfaction Objective: to determine the degree of satisfaction of patients undergoing colpocleisis and urinary symptoms most frequently encountered throughout the first year post-surgery Methods:cross-sectional study is not experimental. validated questionnaire post-surgical satisfaction in patients undergoing colpocleisis during periods 2013-2014, by telephone, in his first post-surgical year was applied. The data obtained are tabulated Results: total patients were surveyed between satisfied and very satisfied and indicated they would undergo surgery. The average age of patients was 76 years. 50% of patients had urinary urge incontinence, anal incontinence 15%, 35% showed no symptoms. Patients who had type IV prolapses, presented some pelvic symptoms. Conclusion: The level of satisfaction delas patients undergoing colpocleisis is high, you can continue to offer as surgical alternative for women without sexual activity, the most common pelvic symptoms were urinary urge incontinence and anal incontinence in patients with higher degree of prolapse.
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Prolapso Uterino/cirugía , Incontinencia UrinariaRESUMEN
Abstract Objective: to identify risk factors related to overactive bladder syndrome. Method: a cross-sectional study was performed with elderly women (>60 years) from the community of Ceilândia, in the Distrito Federal, Brazil, with or without symptoms of OBS, who were evaluated through interviews and questionnaires. The clinical and sociodemographic variables analyzed were: age; body mass index (BMI); parity, schooling, previous abdominal and urogynecologic surgeries, physical activity, smoking, constipation, systemic arterial hypertension (SAH), diabetes mellitus; depression and anxiety. The questionnaires applied were the Overactive Bladder Awareness Tool (OAB-V8), the Geriatric Depression Scale and the Beck Anxiety Scale. Data were analyzed descriptively. Binary logistic regression was used to evaluate the significant associations between the independent variables and the outcome of interest. Risk ratios were calculated for each independent variable with 95% confidence intervals. Result: A total of 372 volunteers were recruited, 292 of whom were eligible. Of these, 172 were allocated to the case group (58.9%) and 120 (41.1%) were control subjects. The two groups were homogeneous between one another. There was a high prevalence of OBS in the study population and significant differences for the variables presence of SAH, abdominal surgery and pelvic surgery, with the case group presenting a higher frequency of these events. In multivariate analysis, it was observed that an active sexual life reduces the chance of having OBS by 70.8%, while urogynecologic surgeries increase this risk 3.098 times. Conclusion: In univariate logistic regression analysis, BMI, SAH, a previous history of abdominal and urogynecologic surgery, number of abortions and the presence of symptoms of depression and anxiety, were found to be factors associated with OBS. AU
Resumo Objetivo: Identificar os fatores clínicos e sociodemográficos associados à Síndrome da Bexiga Hiperativa (SBH). Método: Estudo transversal, realizado com idosas (>60 anos) da comunidade de Ceilândia, DF, Brasil; avaliadas por meio de entrevistas e questionários. As variáveis clínicas e sociodemográficas analisadas foram: idade; índice de massa corpórea (IMC); paridade, escolaridade, cirurgias abdominais e uroginecológicas prévias, prática de atividade física, tabagismo, constipação, hipertensão arterial sistêmica (HAS), diabetes mellitus; depressão e ansiedade. Os questionários aplicados foram Overactive Bladder Awerenees Tool (OAB-V8), Escala de Depressão Geriátrica e Escala de Ansiedade de Beck. Os dados foram analisados descritivamente. Utilizou-se a regressão logística binária para avaliar as associações significativas entre as variáveis independentes e o desfecho de interesse. As razões de risco foram calculadas para cada variável independente com intervalos de 95% de confiança. Resultados: Recrutou-se 372 voluntárias, sendo elegíveis 292, destas, 172 eram grupo caso (58,9%) e 120 (41,1%) eram grupo controle. Observou-se alta prevalência de SBH na população estudada, além de diferenças significativas para as variáveis: presença de HAS; ter realizado cirurgia abdominal ou cirurgia pélvica, sendo que o grupo caso apresentou maior frequência desses eventos. Na análise multivariada, observou-se que vida sexual ativa reduz em 70,8% a chance de ter SBH, e cirurgias uroginecológicas aumentam em 3,098 vezes esse risco. Conclusão: Na análise de regressão logística univariada, o IMC, a HAS, a história prévia de cirurgia abdominal e uroginecológica, quantidade de abortos, presença de sintomas de depressão e ansiedade, apresentaram-se como fatores associados à SBH. AU
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Humanos , Femenino , Anciano , Salud del Anciano , Factores de Riesgo , Vejiga Urinaria Hiperactiva , Incontinencia Urinaria de UrgenciaRESUMEN
Introduction: Urinary incontinence (UI) is prevalent in women, and the frequency of its clinical subtypes varies according to the population studied and the choice of diagnostic criteria. The aim of this study was to evaluate the distribution of the most common subtypes stress urinary incontinence (SUI) and mixed urinary incontinence (MUI) and their correlation with demographic, clinical and reproductive factors of patients seen at the university hospital of Universidade Federal do Rio de Janeiro. Methods: This cross-sectional study was conducted in a referral service of a tertiary care center. A retrospective analysis of records of 770 women referred to the urogynecologic outpatient clinic was performed. The clinical diagnosis of UI subtype was established in accordance with international standardization. Women presenting with SUI and MUI were compared in terms of age, reproductive history, comorbidities, medications used and gynecological surgeries. The effect of independent variables was assessed through multiple regression analyses. Results: The frequency of the clinical diagnosis of MUI and SUI was, respectively, 54.6% and 31.8%. Factors associated with MUI when compared with SUI were diabetes mellitus (odds ratio, OR = 1.75; 95% confidence interval, 95% CI = 1.08; 2.85) and perineoplasty (OR = 1.79; 95% CI = 1.18; 2.72). Age showed a borderline significance (p = 0.05). Conclusions: The distribution of UI subtypes was different from the distribution found in populational studies, which shows the specific aspects of women referred for specialized care. MUI was the most common subtype and was associated with previous vaginal surgery and diabetes mellitus when compared with SUI (AU)
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Humanos , Femenino , Adulto , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Diabetes Mellitus/epidemiología , Procedimientos Quirúrgicos Ginecológicos/estadística & datos numéricos , Incontinencia Urinaria/epidemiología , Brasil/epidemiología , Comorbilidad , Histerectomía/estadística & datos numéricos , Prolapso de Órgano Pélvico/cirugía , Prevalencia , Estudios RetrospectivosRESUMEN
Abstract Introduction: Overactive bladder (OAB) is a clinical diagnosis of irritating urinary symptoms that influence on sufferers' life quality. There are effective treatments described in literature, but most of them present adverse effects. One way of treatment is the use of electrical stimulation, which has been widely used, but studies show varying results. Objective: To verify if intracavitary electrical stimulation can be effective in patients with OAB. Methods: online databases were searched with specific descriptors to find randomized clinical trials on overactive bladder treated with intracavitary electrical stimulation. Only articles with score equal or higher than 5 in methodological PEDro scale were used and those that described intra and / or inter-group P-value. Results: 217 articles were found, but only 6 were analyzed by the selection criteria. The studies show that electrical stimulation promotes the reduction of urinary frequency, urinary incontinence, nocturia, urgency and the number of protectors used, and improvements in maximum cystometric bladder capacity, symptoms of OAB and quality of life. Conclusion: Electrical stimulation was effective in patients with OAB and can be used before any invasive treatment due to none side effects.
Resumo Introdução: A bexiga hiperativa (BH) é um diagnóstico clínico de sintomas urinários irritantes que influenciam na qualidade de vida de seus portadores. Existem tratamentos eficazes descritos na literatura, porém a maioria deles apresenta efeitos adversos. Uma das formas de tratar é utilizando a eletroestimulação, a qual vem sendo muito utilizada, porém os estudos publicados apresentam resultados variados. Objetivo: Verificar se a eletroestimulação intracavitária pode ser eficaz nos distúrbios urinários de pacientes com BH. Métodos: Foram utilizadas bases de dados online com descritores específicos para busca de experimentos controlados randomizados, com pacientes portadores de BH tratados com eletroestimulação intracavitária. Foram selecionados apenas artigos com pontuação maior/igual a 5 na escala metodológica PEDro e que descrevessem P-valor intra e/ou intergrupos. Resultados: Foram encontrados 217 artigos, porém somente 6 atenderam aos critérios de seleção. A eletroestimulação promoveu a redução da frequência urinária, perda urinária, noctúria, urgência e do número de protetores utilizados diariamente, além de aumentar a capacidade cistométrica máxima da bexiga, melhorar os sintomas da BH e a qualidade de vida. Conclusão: A eletroestimulação mostrou-se eficaz em pacientes com BH, e por não apresentar efeitos colaterais, pode ser utilizada antes de qualquer tratamento invasivo.
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Abstract The overactive bladder (OAB) has a significant negative impact on the quality of life of patients. Antimuscarinics have become the pharmacological treatment of choice for this condition. The objective of this systematic review and meta-analysis is to examine the evidence from randomized clinical trials about the outcomes of the antimuscarinic drugs available in Brazil on OABs. We searched MEDLINE and the Cochrane Central Register of Controlled Trials from the inception of these databases through to September 2015. The primary outcome measures were the mean decrease in urge urinary incontinence episodes and the mean decrease in the frequency of micturition. The results suggest that there is a moderate to high amount of evidence supporting the benefit of using anticholinergic drugs in alleviating OAB symptoms when compared with placebo. It is still not clear whether any of the specific drugs that are available in Brazil offer advantages over the others. These drugs are associated with adverse effects (dry mouth and constipation), although they are not related to an increase in the number of withdrawals.
Resumo A bexiga hiperativa determina um impacto negativo na qualidade de vida dos nossos pacientes. Os antimuscarínicos tornaram-se o tratamento farmacológico de escolha para essa condição. O objetivo desta revisão sistemática e metanálise é examinar as melhores evidências científicas sobre estas medicações disponíveis no Brasil no tratamento de mulheres com bexiga hiperativa. As bases de dados utilizadas foram MEDLINE e a biblioteca da Cochrane, das quais selecionamos os ensaios clínicos randomizados até setembro de 2015. Os principais desfechos analisados foram a diminuição dos episódios de incontinência urinária de urgência e a diminuição da frequência de micção. Os resultados sugerem que as drogas existentes no Brasil sustentam o benefício dos anticolinérgicos no alívio dos sintomas da bexiga hiperativa quando comparadas como placebo. Emtermos de eficácia, as medicações apresentam resultados semelhantes no controle dos sintomas. Essas drogas estão associadas a efeitos adversos importantes, tais como boca seca e constipação, e esses efeitos adversos não influenciaram no uso da medicação.
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Humanos , Antagonistas Muscarínicos/uso terapéutico , Vejiga Urinaria Hiperactiva/tratamiento farmacológico , Ensayos Clínicos Controlados Aleatorios como Asunto , Resultado del TratamientoRESUMEN
ResumoObjetivo:Determinar a efetividade de 20 sessões de estimulação elétrica nervosa transcutânea (TENS) parassacral com periodicidade de duas vezes semanais no tratamento da urgência ou urge-incontinência urinária em crianças e adolescentes.Métodos:Ensaio clínico fase II, envolvendo pacientes com idade entre 5 e 14 anos com urgência ou urge-incontinência urinária. Realizadas 20 sessões de TENS, duas vezes por semana (aparelho Dualpex 961 Quark®). Os resultados foram avaliados pelo diário miccional, ultrassonografia dinâmica do trato urinário inferior (USGD-TUI) pré e pós-tratamento e questionário sobre perdas urinárias em cada sessão.Resultados:A idade média das 25 crianças envolvidas no estudo foi 7,80 ± 2,22 anos, sendo a maioria do sexo feminino (92%) e com urge-incontinência (92%). A comparação dos eventos de perda urinária pré e pós-tratamento foi estatisticamente significativa (p = 0,04); houve regressão do sintoma de perda urinária referida pelos acompanhantes em todas as crianças que completaram a 20ª sessão; os parâmetros da USGD-TUI, embora não estatisticamente significativos, demonstraram redução do percentual de crianças com contrações detrusoras (62,5% para 43,5%); maior adequação do volume vesical pré-miccional (4,2% versus 19,0%), respectivamente pré e pós-tratamento.Conclusões:A eletroestimulação realizada em duas sessões semanais demonstrou efetividade e metade dos pacientes apresentou regressão da incontinência urinária a partir da 12ª sessão, porém, é necessário maior número de pacientes para confirmação dos resultados obtidos.
AbstractObjective:To determine the effectiveness of 20 twice-weekly sessions of parasacral transcutaneous electrical neural stimulation (TENS) for treatment of urinary urgency and urge-incontinence in children and adolescents.Methods:A Phase II clinical trial was carried out with patients with urinary urgency or urge-incontinence aged between 5 and 14 years. Twenty TENS sessions were conducted, twice weekly, using a Quark® Dualpex 961 apparatus. The variables analyzed were daily micturition, dynamics ultrasonography of the lower urinary tract pre-and post-treatment and responses to a questionnaire on urinary leakage applied during each session.Results:The mean age of the 25 children participating in the study was 7.80 ± 2.22 years, most were female (92%) and had urge-incontinence (92%). The difference in urinary leakage pre- and post-treatment was statistically significant ( p = 0.04); a decline in the symptom of urinary leakage was reported by all caregivers in children who completed the 20th session; the ultrasound parameters, although not statistically significant, showed a reduction in the percentage of children with detrusor contractions (from 62.5% to 43.5%); and a more adequate pre-micturition bladder volume of 4.2% post-treatment compared with 19.0% prior to treatment.Discussion:The electro-stimulation carried out during the twice weekly sessions appeared to be effective and urinary incontinence declined in half of the patients from the 12th session onwards. However, there is a need for a study involving a larger number of patients to confirm the results obtained.
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Humanos , Masculino , Femenino , Preescolar , Niño , Adolescente , Incontinencia Urinaria/terapia , Estimulación Eléctrica Transcutánea del Nervio , Incontinencia Urinaria de Urgencia/terapiaRESUMEN
Identificar o impacto da incontinência urinária (IU) sobre a qualidade de vida (QV), comparar os escores dos domínios de QV em mulheres com incontinência de esforço (IUE), bexiga hiperativa (BH) e incontinência mista (IUM) e estabelecer a associação entre o tipo clínico de IU e o impacto sobre a QV. Foram coletadas informações sobre idade, índice de massa corpórea (IMC) e comorbidades de 181 mulheres incontinentes atendidas em serviço público. O Observou-se diferença significante entre os dois grupos de autoavaliação do impacto da IU para todos os domínios do KHQ. O grupo IUM apresentou piores escores que o grupo IUE para todos os domínios, e o grupo BH, para limitações de atividades diárias e físicas. Houve diferença significante entre as chances de as mulheres dos grupos IUE e IUM reportarem pior impacto de IU na QV (OR=2,9; p=0,02). Assim como em outras populações de serviços especializados, a IUM foi o subtipo mais comum, e a perda urinária comprometeu de forma moderada/grave a QV, afetando o domínio limitações das atividades diárias com maior intensidade. A análise ajustada mostrou que mulheres com IUM apresentam chance aproximadamente três vezes maior de reportarem pior impacto sobre ...
To identify the impact of urinary incontinence (UI) on quality of life (QoL), to compare the scores of QoL domains in women with stress urinary incontinence (SUI), overactive bladder (OAB) and mixed incontinence (MUI) and to establish the association between the clinical type of UI and the impact on QoL. Data of 181 incontinent women attended at a public hospital were collected regarding age, body mass index (BMI) and co-morbidities. King's Health Questionnaire (KHQ) was applied and patients were classified into two groups according to the self-assessment of incontinence impact. KHQ scores were compared by the Mann-Whitney test. Depending on their urinary symptoms, women were divided into SUI, OAB and MUI groups and their scores in the KHQ domains were compared by the Kruskal-Wallis and Dunn tests. The odds ratio (OR) of a woman reporting a worse effect of UI on QoL was estimated using the binary logistic model. The control variables were: age, BMI and number of co-morbidities. A significant difference was found between the two groups of self-assessment of UI impact for all KHQ domains. The MUI group showed worse scores than the SUI group for all domains, and OAB group, for limitation of physical and daily activities. There was a significant difference between the odds of the women in the SUI and MUI groups reporting worse effects of UI on QoL (OR=2.9; p=0.02). As reported at other reference services, MUI was the most commom type, and urinary loss had a moderate/major impact on QoL, affecting mainly role limitations domain. The adjusted analysis showed that women with MUI had almost three times greater odds of reporting worse impact on QoL than women with SUI.
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Humanos , Femenino , Persona de Mediana Edad , Calidad de Vida , Vejiga Urinaria Hiperactiva , Incontinencia Urinaria , Índice de Masa Corporal , Brasil , Estudios Transversales , Autoinforme , Vejiga Urinaria Hiperactiva/complicaciones , Vejiga Urinaria Hiperactiva/fisiopatología , Incontinencia Urinaria/clasificación , Incontinencia Urinaria/complicaciones , Incontinencia Urinaria/fisiopatologíaRESUMEN
Antecedentes: En el alcoholismo, el tema del craving es un asunto controvertido. Sin embargo, se sabe que, si un alcohólico puede hablar del suceso en sus propios términos, aumenta la probabilidad de lograr un afrontamiento exitoso y evitar una recaída. No obstante, se conoce muy poco acerca de dicho afrontamiento y aún menos cuando se alude a él con términos propios del bebedor.Objetivo: Conocer el afrontamiento de la "obsesión mental por beber", expresión que suelen utilizar los miembros de Alcohólicos Anónimos (AA) para hablar de las reacciones características del craving.Método: La muestra incluyó a 192 individuos que habían participado en AA durante 10 años en promedio (DE=7.5 años). Se aplicó un instrumento empírico para medir el afrontamiento (Kr=.86). Se utilizó un conglomerado de dos fases para establecer perfiles.Resultados: El análisis encontró cinco estilos de afrontamiento: 1. evadir situaciones inductoras al tiempo que se busca una solución (evasivo-activo); 2. evadir retrayéndose (evasivo-pasivo); 3. mostrar sentimientos de enojo y no hacer nada (emocional-pasivo); 4. recordar y comparar la vida pasada como alcohólicos activos (revalorativo) y 5. negar cualquier afrontamiento (negador).Discusión y conclusion: Los datos son preliminares, pero ofrecen la oportunidad de ampliar y especificar la forma en que ciertos alcohólicos de nuestro país solucionan un problema tan complejo como es el craving. El agrupamiento de respuestas supone esfuerzos o estilos de afrontar que pueden resultar o no efectivos para lograr una recuperación -por ejemplo, prevenir las recaídas en las personas que asisten a los grupos de AA-, por lo que plantea una importante perspectiva de investigación.
Background: Although craving is a controversial concept in alcoholism research, it is known that if an alcoholic can talk about the event using his own words, the probability of successful coping and prevention of relapse is bigger. However, little is known about such coping, and even less when it is articulated from the drinker's perspective.Objective: To identify the coping mechanism to this event that causes physical and emotional responses similar to those of craving, identified with the own language of Alcoholics Anonymous (AA).Method: The sample consisted of 192 individuals who participated in AA meetings for an average of ten years (SD=7.5). An empirical instrument was developed to measure coping (Kr=.86) and a two-phase conglomerate analysis was used to create categories to develop profiles.Results: The analysis showed five coping profiles suggesting that AA members cope with the event as follow: 1. evading but looking for a direct solution (elusive-active conglomerate), 2. evading but retracting (elusive-liabilities conglomerate), 3. getting upset and doing nothing (emotional-passive conglomerate), 4. remembering and comparing their past life (revalorative conglomerate), and 5. denying (denier conglomerate).Discussion and conclusion: Although the data are preliminary, they offer the opportunity to expand and specify how certain alcoholics solve a complex problem, such as craving. The information concurs with literature in the sense that this grouping of responses assumed those efforts that may be effective or not for the recovery process, for example, to prevent relapses in alcoholics who attend AA groups, so it raises an important research perspective.