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1.
Asian Pac J Cancer Prev ; 24(12): 4133-4138, 2023 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-38156848

RESUMEN

PURPOSE/OBJECTIVE: The purpose of this study is to investigate the effect of treatment couch and immobilization devices on surface dose for megavoltage photon beams. MATERIAL/METHODS: Percentage surface dose (PSD) measurement was carried out in Elekta Synergy™ Linear accelerator using PTW Markus® Parallel plate ionization chamber of volume 0.05cm3 with water equivalent RW3 Slab phantom (PTW, Germany). The measurement depth was considered at 0.07mm. The reference PSD was measured at 0° gantry angle with 10×10cm2, 20×20cm2 and 30×30cm2 field sizes and 100cm SSD for 4MV, 6MV and 15MV photon beams. For comparison, PSD measurement was carried out at 180° gantry angle inclusion of treatment couch (TC), All in One positioning system (AIO - PS) and Vac lok Cushions (VLC). RESULTS: Beam angle at 0°, for field sizes 10×10cm2, 20×20cm2 and 30×30cm2, the PSD was observed as 30.9%, 40.5%, 48.7% for 4MV; 23.7%, 33.8%, 42.2% for 6MV; and 17.0%, 29.6%, 38.6% for 15MV respectively. Beam angle at 180° with TC, an increase in PSD by maximum of 65.0% for 4MV, 64.9% for 6MV and 55.9% for 15MV as compared to 0° angle. The PSD increased when beam angle was 180° with TC and AIO - PS were 65.0% for 4MV, 67.4% for 6MV, and 60.9% for 15MV than 0° angle. Similarly, increased PSD for beam angle at 180° with TC and VLC were 66.8% for 4MV, 66.8% for 6MV and 61.3% for 15MV as compared to 0° angle. CONCLUSION: For all three-photon energies, at 180° gantry angle, the PSD increased significantly in case of TC, VLC, and AIO - PS for all the field sizes as compared to gantry angle at 0°. It is necessary to consider TC, AIO - PS and VLC during dose calculation to ensure accuracy of patient treatment delivery.


Asunto(s)
Fotones , Planificación de la Radioterapia Asistida por Computador , Humanos , Fotones/uso terapéutico , Fantasmas de Imagen , Aceleradores de Partículas , Agua , Dosificación Radioterapéutica
2.
J Appl Clin Med Phys ; 23(7): e13629, 2022 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-35506575

RESUMEN

PURPOSE/OBJECTIVES: To report our 7-year experience with a daily monitoring system to significantly reduce couch position overrides and errors in patient treatment positioning. MATERIALS AND METHODS: Treatment couch position override data were extracted from a radiation oncology-specific electronic medical record system from 2012 to 2018. During this period, we took several actions to reduce couch position overrides, including reducing the number of tolerance tables from 18 to 6, tightening tolerance limits, enforcing time outs, documenting reasons for overrides, and timely reviewing of overrides made from previous treatment day. The tolerance tables included treatment categories for head and neck (HN) (with/without cone beam CT [CBCT]), body (with/without CBCT), stereotactic body radiotherapy (SBRT), and clinical setup for electron beams. For the same time period, we also reported treatment positioning-related incidents that were recorded in our departmental incident report system. To verify our tolerance limits, we further examined couch shifts after daily kilovoltage CBCT (kV-CBCT) for the patients treated from 2018 to 2021. RESULTS: From 2012 to 2018, the override rate decreased from 11.2% to 1.6%/year, whereas the number of fractions treated in the department increased by 23%. The annual patient positioning error rate was also reduced from 0.019% in 2012, to 0.004% in 2017 and 0% in 2018. For patients treated under daily kV-CBCT guidance from 2018 to 2021, the applied couch shifts after imaging registration that exceeded the tolerance limits were low, <1% for HN, <1.2% for body, and <2.6% for SBRT. CONCLUSIONS: The daily monitoring system, which enables a timely review of overrides, significantly reduced the number of treatment couch position overrides and ultimately resulted in a decrease in treatment positioning errors. For patients treated with daily kV-CBCT guidance, couch position shifts after CBCT image guidance demonstrated a low rate of exceeding the set tolerance.


Asunto(s)
Radiocirugia , Radioterapia de Intensidad Modulada , Tomografía Computarizada de Haz Cónico/métodos , Humanos , Posicionamiento del Paciente/métodos , Radiocirugia/métodos , Planificación de la Radioterapia Asistida por Computador/métodos , Errores de Configuración en Radioterapia/prevención & control , Radioterapia de Intensidad Modulada/métodos
3.
J Appl Clin Med Phys ; 23(6): e13616, 2022 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-35488728

RESUMEN

PURPOSE: Increasing number of heavy cancer patients has created challenges in diagnostic imaging and radiation oncology. Practical weight limits of the equipment can become an obstacle both for imaging and treatment of these patients. Most magnetic resonance imaging and computed tomography (CT) tables' static load capacities are between 450 and 500 pounds, and linear accelerator tables can support similar weights depending on the type of the table and manufacturer. One recurring issue we encountered was failure of the treatment couch's longitudinal drive belt due to heavy patients' sudden movement. In several cases, snapping of the longitudinal drive belt occurred when the patient's weight was under 300 lbs (below the rated weight limit). Additionally, we observed vertical deflection of the couch when extended/cantilevered with heavy patients. The purpose of this work was to implement immobilization methods and safety devices for radiation treatment management of heavy patients in order to increase patient/provider safety, prevent treatment couch damage, and reduce treatment disruptions. MATERIALS AND METHODS: We created three safety devices for treatment management of heavy patients. Wooden brace and Scissor jack were used to lock the couch longitudinal axis (while the couch longitudinal drive was floated) during the setup of a heavy patient and absorb the mechanical impulse applied to the couch longitudinal drive belt. Wooden brace was built in house and positioned in between the wall and treatment couch to lock the longitudinal axis. Commercially available 10 in × 10 in scissor jack lift with adjustable height 3 ½ in - 13 in was modified to increase effectiveness and safety. An additional stand was created with adjustable height and rolling rubber wheels to support the couch when extended/cantilevered with heavy patients. RESULTS: Using these devices prevented the longitudinal belt from breaking and improved the patient/therapist safety at eight treatment sites within our network. No farther couch belt failures were observed since devices were introduced for clinical use. All three devices can be used and removed without any modifications done to the treatment couch.


Asunto(s)
Aceleradores de Partículas , Radioterapia Conformacional , Humanos , Movimiento , Equipos de Seguridad , Planificación de la Radioterapia Asistida por Computador/métodos , Tomografía Computarizada por Rayos X/métodos
4.
J Appl Clin Med Phys ; 22(2): 77-84, 2021 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-33440075

RESUMEN

PURPOSE: The treatment couch position of a patient in external beam radiation therapy (EBRT) is usually acquired during initial treatment setup. This procedure has shown potential failure modes leading to near misses and adverse events in radiation treatment. This study aims to develop a method to automatically determine the couch position before setting up a patient for initial treatment. METHODS: The Qfix couch-tops (kVue and DoseMax) have embedded reference marks (BBs) indicating its index levels and couch centerline. With the ESAPI, a C# script was programmed to automatically find the couch-top and embedded BBs in the planning CT and derive the treatment couch position according to treatment isocenter of a plan. Couch positions of EBRT plans with the kVue couch-top and SBRT plans using the DoseMax were calculated using the script. The calculation was evaluated by comparing calculated positions with couch coordinates captured during the initial treatment setup after image guidance. The calculations were further compared with daily treatment couch positions post image-guided adjustment for each treatment fraction. RESULTS: For plans using the kVue couch-top for various treatment sites, the median (5-95 percentiles) differences between calculated and captured couch positions were 0.1 (-0.2 - 0.9), 0.5 (-1.1-2.0), 0.10 (-1.3-1.3) cm in the vertical, longitudinal, and lateral direction respectively. For the DoseMax couch-top, the median differences were 0.1 (-0.2-0.7), 0.2 (-0.3-1.1), and 0.2 (-0.7-0.9) cm in respective direction. The calculated positions were within 1 and 2 cm from the mean fraction positions for 95% patients on DoseMax and kVue couch-top respectively. CONCLUSIONS: A method that automatically and accurately calculates treatment couch position from simulation CT was implemented in Varian Eclipse for Qfix couch-tops. This technique increases the efficiency of patient setup and enhances patient safety by reducing the risks of positioning errors.


Asunto(s)
Planificación de la Radioterapia Asistida por Computador , Radioterapia de Intensidad Modulada , Simulación por Computador , Humanos , Posicionamiento del Paciente , Dosificación Radioterapéutica
5.
Radiol Phys Technol ; 13(2): 195-200, 2020 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-32078138

RESUMEN

Short and semi-automated quality assurance (QA) programs are becoming one of the most popular and highly demanding tasks in radiotherapy. The current research investigates the accuracy of a four degrees of freedom (4DoF) medical linear accelerator couch positioning with a fast and accurate method based on images acquired using an electronic portal imaging device (EPID). An accurate EPID QA phantom and a proper in-house code were used. A Siemens medical linear accelerator equipped with an a-Si EPID was used to acquire portal images. For verifying the mechanical performance of the EPID positioning, EPID sensitivity, and accuracy of the code response from the image processing point of view were investigated. To characterize the results, three deviations in the phantom positioning were deliberately created. The translational and rotational displacements of the treatment couch were then evaluated. The loading effect on the treatment couch was then investigated. The results of prerequisite tests, including the mechanical performance of the EPID, and the sensitivity and accuracy of the recognition codes, were assessed. The results were found to be within the tolerance range reported at AAPM TG-142. The mean deviations of the tests between expected and measured displacements by 4DoF treatment couch were found to be 0.13° ± 0.11°, 0.12 ± 0.17 mm, 0.17 ± 0.13 mm, and 0.04 ± 0.09 mm for rotational, longitudinal, lateral, and vertical shifts, respectively. The results showed that the proposed method is a reliable and fast approach to find the uncertainties occurring intreatment couch positioning.


Asunto(s)
Equipos y Suministros Eléctricos , Aceleradores de Partículas
6.
J Appl Clin Med Phys ; 20(10): 152-159, 2019 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-31535782

RESUMEN

INTRODUCTION: Intrafractional motion can cause substantial uncertainty in precision radiotherapy. Traditionally, the target volume is defined to be sufficiently large to cover the tumor in every position. With the robotic treatment couch, a real-time motion compensation can improve tumor coverage and organ at risk sparing. However, this approach poses additional requirements, which are systematically developed and which allow the ideal robotic couch to be specified. METHODS AND MATERIALS: Data of intrafractional tumor motion were collected and analyzed regarding motion range, frequency, speed, and acceleration. Using this data, ideal couch requirements were formulated. The four robotic couches Protura, Perfect Pitch, RoboCouch, and RPSbase were tested with respect to these requirements. RESULTS: The data collected resulted in maximum speed requirements of 60 mm/s in all directions and maximum accelerations of 80 mm/s2 in the longitudinal, 60 mm/s2 in the lateral, and 30 mm/s2 in the vertical direction. While the two robotic couches RoboCouch and RPSbase completely met the requirements, even these two showed a substantial residual motion (40% of input amplitude), arguably due to their time delays. CONCLUSION: The requirements for the motion compensation by an ideal couch are formulated and found to be feasible for currently available robotic couches. However, the performance these couches can be improved further regarding the position control if the demanded speed and acceleration are taken into account as well.


Asunto(s)
Movimiento , Neoplasias/fisiopatología , Posicionamiento del Paciente , Planificación de la Radioterapia Asistida por Computador/métodos , Radioterapia Asistida por Computador/instrumentación , Robótica/métodos , Algoritmos , Humanos , Neoplasias/radioterapia , Dosificación Radioterapéutica , Radioterapia Asistida por Computador/métodos
7.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-734322

RESUMEN

Objective To retrospectively analyze the setup error in radiotherapy of somal tumors and body metastases using the ExacTrac X-ray portal image,and to evaluate the feasibility and effectiveness of 6D setup error correction in body radiotherapy.Methods The translational and rotational setup errors were calculated by registering the bony structures on the ExacTrac X-setup images to that of the digitally reconstructed setup images,and the corresponding residual errors were calculated together.Results The translational and rotational setup errors in the x (left-right),y (superior-inferior),z (anterior-posterior) and Rx (sagittal),Ry (transverse),Rz (coronal) directions were(2.27±2.02) mm,(4.49±2.52) mm,(2.27± 1.37) mm and (1.02 ± 0.73) °,(0.67 ± 0.68) °,(0.76 ± 0.84) °,respectively.The residual translational and rotational setup errors in the x(r),y(r),z(r) and Rx(r),Ry(r),Rz(r) directions were(0.27±0.48)mm,(0.37±0.45)mm,(0.22±0.30)mm and (0.17±0.33)°,(0.14±0.34)°,(0.16± 0.28) ° respectively.Conclusions Besides the translational setup errors,a certain amount of rotational setup errors exist in radiotherapy of somal tumors and body metastases.By using the 6D setup error correction of the ExacTrac system,a translational less than 0.4 mm and rotational setup errors less than 0.2° could be achieved.

8.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-708007

RESUMEN

Objective To investigate the dosimetric effect of carbon fiber couch through virtual simulation in the XiO treatment planning system (TPS).Methods A treatment couch model of iBEAM evo Extension 650 was scanned with a big bore spiral CT and its contour was stored in the XiO TPS.The attenuation coefficient of couch was obtained by measuring the attenuated dose with and without a solid water phantom on the couch at different gantry angles (100°-180°).The optimal relative electron density (RED) values of the carbon fiber (CF) cover and foam core (FC) were adjusted according to the comparison between measured and simulated attenuation dose.The effects of the couch in the TPS on pass rate were evaluated by Octavius 4D phantom with 10 cases with lung cancer.Results The optimal RED values of CF and FC were 0.75 and 0.10 g/cm3,respectively.The measured attenuation error was the maximal at gantry angle of 120° (4.84%) without the treatment couch in the TPS.The average measured attenuation errors without the couch in the TPS dropped significantly from (2.54 ± 1.48) % to (-0.04 ± 0.36) % after inclusion of the treatment couch during dose calculation (Z =-3.621,P < 0.05).The three-dimensional dose verification γ pass rate (3 mm/3%) without the couch increased significantly from (91.79± 1.25)% to (94.74± 1.69)% after inclusion of the couch in the dose calculation (t =6.027,P < 0.05).Conclusions The effect of couch on the attenuation dose is significant.Inclusion of a virtual model of couch in XiO TPS can simulate the attenuation effect properly and improve the accuracy of dose calculation.

9.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-708183

RESUMEN

Objective A self-made tiltable treatment couch was adopted for CT simulation positioning and radiotherapy to evaluate the feasibility and effectiveness to minimize the setup errors. Methods Twenty-two patients with thoracic and abdominal tumors receiving radiotherapy in Department of Radiation Oncology,Peking Union Medical College between March and September 2016 were recruited in this study. All patients were randomly divided into the experimental(n=11)and control groups(n=11).In the study group,the tiltable treatment couch was adopted to switch the patients from the standing position to the supine position,and conventional supine position was utilized in the control group. All patients received CT positioning under spontaneous breathing. Image registration was performed according to the standard recommendations of IGRT group. The image registration data for the translational and rotation errors of CBCT were recorded and analyzed. The setup errors were calculated by four-parameter model between two groups. Results In the experimental group,the translational error of the x direction was(-0.012±0.128)cm with a variation range of(0.29-0.70 cm),(0.272±0.123)cm for the y direction(0.23-0.70 cm)and(0.089± 0.105)cm for the z direction(0.14-0.53 cm),respectively. In the control group,the translational error of the x direction was(0.006±0.198)cm(0.27-0.75 cm),(-0.108±0.396)cm for the y direction(0.56-2.08 cm)and(- 0.096± 0.176)cm for the z direction(0.34-0.89 cm), respectively. Conclusions Application of the self-made tiltable treatment couch can enhance the setup reproducibility and reduce the setup errors,especially in the y direction during radiotherapy for the thoracic and abdominal tumors.

10.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi ; 34(2): 297-302, 2017 04 25.
Artículo en Chino | MEDLINE | ID: mdl-29745588

RESUMEN

In order to decrease the radiotherapy error caused by target motion, an adaptive radiation therapy system for target movement compensation has been designed and passed by simulation test. The real-time position of the target labelled by a mark was captured by the control system and compared with the reference point. Then the treatment couch was controlled to move in the opposite direction for compensation according to that position information. The three dimensional movement of the treatment bed relied on three independent stepping motors which were controlled by a control system. Experiments showed that the adaptive radiation therapy system was able to reduce the therapy error caused by target movement. It would be useful in radiotherapy clinical practice with high real-time position precision.

11.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-496875

RESUMEN

Objective To construct the uniform electron density couch model (model A ED =0.25) and two components non uniform electron density couch model (model B FD =0.5and foam core=0.1) in the Monaco treatment planning system for the iBEAM(R) evo Extension 415,and to compare which model can better quantify the treatment couch influence on radiation dose.Methods Phantom was positioned in the center of the couch,the attenuation of the couch was evaluated with 6 MV for a field size of 10 cm× 10 cm.Dose measurements of couch attenuation were performed at gantry angles from 180.0° to 122.8°,using a 0.125cc semiflex ionization chamber (PTW),isocentrically placed in the center of a homogeneous cylindrical phantom.Each experimental setup was first measured on the linear accelerator and then reproduced in the TPS.By adjusting the relative-to water electron density (ED) values of the couch,the measured attenuation was replicated.The model accuracies of the model A and model B were evaluated by comparing the measured and calculated results at the minimum computational grid (2 mm) and maximum computing grid (5 mm),respectively.Results The maximum measured and calculated percentage deviation for the central phantom position was 4.01%.The couch model was included in the TPS with a uniform ED of 0.25 or a 2 component model with a fiber ED=0.5 and foam core ED=0.1.For model A and B under 2 and 5 mm voxel grid size,the mean absorbed dose with couch was reduced to 0.61%,0.84%,0.71% and 0.92%from 2.8% without couch.Conclusions Model A has a good agreement between measured and calculated dose distributions for all different voxel grid sizes and gantry angles.It can accurately describes the dose perturbations due to the presence of the couch and should therefore be used during treatment planning.

12.
Phys Med ; 31(8): 1080-1084, 2015 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-26431578

RESUMEN

PURPOSE: This study aims at the assessment of dose error in patients undergoing radiotherapy due to treatment couch of Co-60 teletherapy unit. MATERIALS AND METHODS: In this study beam attenuation due to treatment couch of Co-60 unit was measured in air for different gantry angles and field sizes. Polymethylmethacrylate (PMMA) phantom was used to estimate the effect of depth on attenuation. Impact of couch on surface dose was also evaluated. RESULTS: Beam attenuation due to couch was in the range of 0.5-28% for different gantry angles with standard field size of 10 × 10 cm(2) with optimum position of metallic cranks. Maximum attenuation (29%) was observed with smallest field size i.e. 5 × 5 cm(2). Beam attenuation has been found higher in phantom as compared to that in air However, no particular trend of attenuation has been noted with varying depth of phantom. A 6% increase in surface dose has also been observed due to couch insertion for normal beam incidence. Maximum error of 80% is also note-worthy for most unfavorable situation of irradiation at 180 degree through the metallic cranks. CONCLUSION: It has been determined that ignoring the treatment couch and its accessories can result in dose error of 0.5-80%, depending on gantry angle, field size and position of couch accessories. Therefore, consideration of dose error due to couch during treatment planning is recommended.


Asunto(s)
Nylons , Dosis de Radiación , Teleterapia por Radioisótopo/instrumentación , Errores de Configuración en Radioterapia , Dosificación Radioterapéutica , Piel/efectos de la radiación
13.
Med Dosim ; 40(4): 304-13, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-25934344

RESUMEN

The effect of a treatment couch on dose perturbation is not always fully considered in intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT). In the course of inverse planning radiotherapy techniques, beam parameter optimization may change in the absence of the couch, causing errors in the calculated dose distributions. Although modern treatment planning systems (TPS) include data for the treatment couch components, they are not manufactured identically. Thus, variations in their Hounsfield unit (HU) values may exist. Moreover, a radiotherapy facility may wish to have a third-party custom tabletop installed that is not included by the TPS vendor. This study demonstrates a practical and simple method of acquiring reliable computed tomography (CT) data for the treatment couch and shows how the absorbed dose calculated with the modeled treatment couch can differ from that with the default treatment couch found in the TPS. We also experimentally verified that neglecting to incorporate the treatment couch completely in the treatment planning process might result in dose differences of up to 9.5% and 7.3% for 4-MV and 10-MV photon beams, respectively. Furthermore, 20 RapidArc and IMRT cases were used to quantify the change in calculated dose distributions caused by using either the default or modeled couch. From 2-dimensional (2D) ionization chamber array measurements, we observed large dose distribution differences between the measurements and calculations when the couch was omitted that varied according to the planning technique and anatomic site. Thus, incorporating the treatment couch in the dose calculation phase of treatment planning significantly decreases dose calculation errors.


Asunto(s)
Tomografía Computarizada de Haz Cónico , Modelos Teóricos , Planificación de la Radioterapia Asistida por Computador/métodos , Radioterapia de Intensidad Modulada/instrumentación , Humanos
14.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-469693

RESUMEN

Objective To evaluate the effect of carbon fiber couch on dose distribution of radiotherapy planning and verification pass rate.Methods Establishing the carbon fiber treatment couch model in Pinnacle8.0m Treatment Planning system (TPS),and then this model was used to correct dose calculations of oblique fields in the treatment plans of 10 cases of nasopharyngeal carcinoma,10 cases of breast cancer and 10 cases of lung cancer and evaluate the effect of carbon fiber couch on the whole dose distribution of the plans.Then these plans were measured by three-dimensional dose verification equipment Delta4 to confirm the improvement extent of Gamma pass rate after considering the carbon fiber treatment couch.Results For the majority of plans,when the carbon fiber couch was taken into consideration,the target doses was significantly reduced (4772 cGy-7266 cGy vs.4859 cGy-7347 cGy,P=0.000-0.002) and the relative deviation of D95 was 1% to 3%.Measurement results of Delta4 showed that Gamma pass rate (3 mm/3% criteria) increased in all plans (96.4%-98.8% vs.93.4%-97.3%,P =0.000),some of that were up to 5 percentage when the couch model was applied.Conclusions Target doses will be overestimated if the treatment couch is ignored in TPS measurement.,However it should arouse enough attention when the disease with smaller doses corresponding gradient.

15.
J Med Phys ; 31(2): 67-71, 2006 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-21206667

RESUMEN

Multiple fields in IMRT and optimization allow conformal dose to the target and reduced dose to the surroundings and the regions of interest. Thus we can escalate the dose to the target to achieve better tumor control with low morbidity. Orientation of multiple beams can be achieved by i) different gantry angles, ii) rotating patient's couch isocentrically. In doing so, one or more beam may pass through different materials like the treatment couch, immobilization cast fixation plate, head and neck rest or any other supportive device. Our observations for 6MV photon beam on PRIMUS-KXE2 with MED-TEC carbon fiber tabletop and 10 × 10 cm(2) field size reveals that the maximum dose attenuation by the couch was of the order of 2.96% from gantry angle 120-160°. Attenuation due to cast fixation base plate of PMMA alone was of the order of 5.8-10.55% at gantry angle between 0 and 90°. Attenuation due to carbon fiber base plate alone was 3.8-7.98%. Attenuation coefficient of carbon fiber and PMMA was evaluated and was of the order of 0.082 cm(-1) and 0.064 cm(-1) respectively. Most of the TPS are configured for direct beam incidence attenuation correction factors only. Whereas when the beam is obliquely incident on the couch, base plate, headrest and any other immobilization device get attenuated more than the direct beam incidence. The correction factors for oblique incidence beam attenuation are not configured in most of the commercially available treatment planning systems. Therefore, such high variations in dose delivery could lead to under-dosage to the target volume for treatments requiring multiple fields in IMRT and 3D-CRT and need to be corrected for monitor unit calculations.

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