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1.
Sci Rep ; 14(1): 16130, 2024 Jul 12.
Artículo en Inglés | MEDLINE | ID: mdl-38997398

RESUMEN

The mechanism of selectivity in ion channels is still an open question in biology. Recent studies suggest that the selectivity filter may exhibit quantum coherence, which could help explain how ions are selected and conducted. However, environmental noise causes decoherence and loss of quantum effects. It is hoped that the effect of classical noise on ion channels can be modeled using the framework provided by quantum decoherence theory. In this paper, the behavior of the ion channel system was simulated using two models: the Spin-Boson model and the stochastic Hamiltonian model under classical noise. Additionally, using a different approach, the system's evolution was modeled as a two-level Spin-Boson model with tunneling, interacting with a bath of harmonic oscillators, based on decoherence theory. We investigated under what conditions the decoherence model approaches and deviates from the noise model. Specifically, we examined Gaussian noise and Ornstein-Uhlenbeck noise in our model. Gaussian noise shows a very good agreement with the decoherence model. By examining the results, it was found that the Spin-Boson model at a high hopping rate of potassium ions can simulate the behavior of the system in the classical noise approach for Gaussian noise.

2.
Entropy (Basel) ; 25(10)2023 Oct 17.
Artículo en Inglés | MEDLINE | ID: mdl-37895579

RESUMEN

One of the main obstacles toward building efficient quantum computing systems is decoherence, where the inevitable interaction between the qubits and the surrounding environment leads to a vanishing entanglement. We consider a system of two interacting asymmetric two-level atoms (qubits) in the presence of pure and correlated dephasing environments. We study the dynamics of entanglement while varying the interaction strength between the two qubits, their relative frequencies, and their coupling strength to the environment starting from different initial states of practical interest. The impact of the asymmetry of the two qubits, reflected in their different frequencies and coupling strengths to the environment, varies significantly depending on the initial state of the system and its degree of anisotropy. For an initial disentangled, or a Werner, state, as the difference between the frequencies increases, the entanglement decay rate increases, with more persistence at the higher degrees of anisotropy in the former state. However, for an initial anti-correlated Bell state, the entanglement decays more rapidly in the symmetric case compared with the asymmetric one. The difference in the coupling strengths of the two qubits to the pure (uncorrelated) dephasing environment leads to higher entanglement decay in the different initial state cases, though the rate varies depending on the degree of anisotropy and the initial state. Interestingly, the correlated dephasing environment, within a certain range, was found to enhance the entanglement dynamics starting from certain initial states, such as the disentangled, anti-correlated Bell, and Werner, whereas it exhibits a decaying effect in other cases such as the initial correlated Bell state.

3.
Nanomaterials (Basel) ; 12(16)2022 Aug 15.
Artículo en Inglés | MEDLINE | ID: mdl-36014665

RESUMEN

Single photon sources (SPS) based on semiconductor quantum dot (QD) platforms are restricted to low temperature (T) operation due to the presence of strong dephasing processes. Although the integration of QD in optical cavities provides an enhancement of its emission properties, the technical requirements for maintaining high indistinguishability (I) at high T are still beyond the state of the art. Recently, new theoretical approaches have shown promising results by implementing two-dipole-coupled-emitter systems. Here, we propose a platform based on an optimized five-dipole-coupled-emitter system coupled to a cavity which enables perfect I at high T. Within our scheme the realization of perfect I single photon emission with dissipative QDs is possible using well established photonic platforms. For the optimization procedure we have developed a novel machine-learning approach which provides a significant computational-time reduction for high demanding optimization algorithms. Our strategy opens up interesting possibilities for the optimization of different photonic structures for quantum information applications, such as the reduction of quantum decoherence in clusters of coupled two-level quantum systems.

4.
Entropy (Basel) ; 20(8)2018 Jul 27.
Artículo en Inglés | MEDLINE | ID: mdl-33265647

RESUMEN

We present a comparison of a classical and a quantum mechanical calculation of the motion of K+ ions in the highly conserved KcsA selectivity filter motive of voltage gated ion channels. We first show that the de Broglie wavelength of thermal ions is not much smaller than the periodic structure of Coulomb potentials in the nano-pore model of the selectivity filter. This implies that an ion may no longer be viewed to be at one exact position at a given time but can better be described by a quantum mechanical wave function. Based on first principle methods, we demonstrate solutions of a non-linear Schrödinger model that provide insight into the role of short-lived (~1 ps) coherent ion transition states and attribute an important role to subsequent decoherence and the associated quantum to classical transition for permeating ions. It is found that short coherences are not just beneficial but also necessary to explain the fast-directed permeation of ions through the potential barriers of the filter. Certain aspects of quantum dynamics and non-local effects appear to be indispensable to resolve the discrepancy between potential barrier height, as reported from classical thermodynamics, and experimentally observed transition rates of ions through channel proteins.

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