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Beilstein J Org Chem ; 9: 1432-6, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-23946839

RESUMEN

The cis- and trans-stereoselective radical additions to α-methylene-γ-alkyl- γ-lactams were investigated and the scope and limitation of the reaction were also revealed. This stereoselective radical reaction was used for synthesis of chiral pyroglutamic acid derivatives starting from a commercially available chiral amino acid.

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