Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 89
Filtrar
1.
JMIR Res Protoc ; 13: e53541, 2024 Jul 15.
Artículo en Inglés | MEDLINE | ID: mdl-39008345

RESUMEN

BACKGROUND: Mental health problems among workers cause enormous losses to companies in Japan. However, workers have been considered to have limited access to psychological support because of time constraints, which makes it difficult for them to engage in face-to-face psychological support interventions. OBJECTIVE: This study aimed to present an intervention protocol that describes a randomized controlled trial to examine whether brief guided mindfulness meditation (MM) or self-compassion meditation (SCM) provided by a smartphone app is effective for mental health and work-related outcomes among workers. METHODS: This is an open-label, 3-arm randomized controlled trial. The participants will be recruited through an open call on relevant websites with the following inclusion criteria: (1) employees who are working more than 20 hours per week, (2) between the ages of 18 and 54 years, (3) not on a leave of absence, (4) not business owners or students, and (5) not currently diagnosed with a mental disorder and have a Kessler Psychological Distress Scale-6 score below 13 points. We will include 200 participants and randomly assign them to an SCM course (n=67), an MM course (n=67), and a waitlist group (n=66). The intervention groups (SCM and MM) will be instructed to engage in daily guided self-help, self-compassion, and MMs lasting 6-12 minutes per day over 4 weeks. Primary outcomes will include psychological distress and job performance, and secondary outcomes will include somatic symptoms, cognitive flexibility, self-esteem, self-compassion, perceived stress, well-being, emotion regulation, work engagement, anger, psychological safety, and creativity. All procedures were approved by the ethics committee of the University of Tokyo (22-326). All participants will be informed of the study via the websites, and written informed consent will be collected via web-based forms. RESULTS: The recruitment of participants began in December 2022, and the intervention began in January 2023. As of September 2023, a total of 375 participants have been enrolled. The intervention and data collection were completed in late October 2023. CONCLUSIONS: This study will contribute to the development of effective self-care intervention content that will improve mental health, work performance, and related outcomes and promote mindful and self-compassionate attitudes when faced with distress. TRIAL REGISTRATION: University Hospital Medical Information Network Clinical Trials Registry UMIN000049466; https://tinyurl.com/23x8m8nf. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/53541.


Asunto(s)
Empatía , Salud Mental , Atención Plena , Teléfono Inteligente , Adolescente , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven , Japón , Meditación/métodos , Atención Plena/métodos , Ensayos Clínicos Controlados Aleatorios como Asunto
2.
J Oral Rehabil ; 51(9): 1730-1736, 2024 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-38873731

RESUMEN

OBJECTIVE: Temporomandibular disorders (TMD) may develop, especially among girls, during the adolescence period. The aim of this study was to study if information and advice in a school setting could prevent development of TMD symptoms and headaches during the early teenage period. METHODS: Thirteen-year-old girls, at 19 upper elementary schools were invited to participate in a study with structured information about the jaw system, TMD symptoms and risk factors, as well as advice how to manage risk factor and TMD. Six hundred and fifty-one girls enrolled, of which 507 girls were followed for 2-2.5 years. Half received information on three occasions (cases), and the other half served as controls. Included in the analysis of incidence of TMD symptoms were those without frequently occurring TMD symptoms (not including headaches) at baseline (n = 396) and included in the analysis of incidence of headaches were those without frequent headaches at baseline (n = 297). RESULT: The 2-year incidence of TMD symptoms was significantly lower in the information cohort (19%) compared to the controls (28%) (p = .03). The 2-year incidence of headaches was lower among those who were allocated to information (30%) compared to controls (40%), but the difference was not statistically significant (p = .099). Cases who had headaches at baseline reported a significantly lower prevalence at follow-up compared to controls (p = .03). CONCLUSION: Standardized information in school settings can prevent development of TMD symptoms and headaches among young girls.


Asunto(s)
Cefalea , Trastornos de la Articulación Temporomandibular , Humanos , Femenino , Cefalea/prevención & control , Cefalea/epidemiología , Adolescente , Trastornos de la Articulación Temporomandibular/epidemiología , Trastornos de la Articulación Temporomandibular/prevención & control , Incidencia , Factores de Riesgo , Servicios de Salud Escolar , Instituciones Académicas , Dolor Facial/prevención & control , Dolor Facial/epidemiología
3.
Zhongguo Dang Dai Er Ke Za Zhi ; 26(3): 297-301, 2024 Mar 15.
Artículo en Chino | MEDLINE | ID: mdl-38557383

RESUMEN

Neurodevelopmental disorders in children have become a significant global public health concern, impacting child health worldwide. In China, the current intervention model for high-risk infants involves early diagnosis and early treatment. However, in recent years, overseas studies have explored novel preventive early intervention strategies for neurodevelopmental disorders in high-risk infants, achieving promising results. This article provides a comprehensive review of the optimal timing, methods, and intervention models of the preventive early intervention strategies for neurodevelopmental disorders in high-risk infants. The aim is to enhance the awareness and knowledge of healthcare professionals regarding preventive early intervention strategies for neurodevelopmental disorders in high-risk infants, facilitate clinical research and application of such interventions in China, and ultimately reduce the incidence of neurodevelopmental disorders in this high-risk population.


Asunto(s)
Trastornos del Neurodesarrollo , Lactante , Niño , Humanos , Trastornos del Neurodesarrollo/prevención & control , Trastornos del Neurodesarrollo/epidemiología , Intervención Educativa Precoz , Factores de Riesgo , China
4.
Implement Res Pract ; 5: 26334895231226193, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38322804

RESUMEN

Background: As the opioid crisis continues to affect communities across the United States, new interventions for screening and prevention are needed to mitigate its impact. Mental health diagnoses have been identified as a risk factor for opioid misuse, and surgical populations and injury survivors are at high risk for prolonged opioid use and misuse. This study investigated the implementation of a novel opioid risk screening tool that incorporated putative risk factors from a recent study in four trauma units across Wisconsin. Method: The screening tool was implemented across a 6-month period at four sites. Data was collected via monthly meeting notes and "Plan, Do, Study, Act" (PDSA) forms. Following implementation, focus groups reflected on the facilitators and barriers to implementation. Meeting notes, PDSA forms, and focus group data were analyzed using the consolidated framework for implementation research, followed by thematic analyses, to generate themes surrounding the facilitators and barriers to implementing an opioid misuse screener. Results: Implementation facilitators included ensuring patient understanding of the screener, minimizing staff burden from screening, and educating staff to encourage engagement. Barriers included infrastructure limitations that prevented seamless administration of the screener within current workflows, overlap of the screener with existing measures, and lack of guidance surrounding treatment options corresponding to risk. Recommended solutions to address barriers include careful timing of screener administration, accommodating workflows, integration of the screening tool within the electronic health record, and evidence-based interventions guided by screener results. Conclusion: Four trauma centers across Wisconsin successfully implemented a pilot opioid misuse screening tool. Trauma providers and unit staff members believe that this tool would be a beneficial addition to their repertoire if their recommendations were adopted. Future research should refine opioid misuse risk factors and ensure screening items are well-validated with psychometric research supporting treatment responses to screener-indicated risk categories.


As the opioid crisis continues to affect communities across the United States, new interventions for early screening and prevention are needed to minimize the related harms. Prior research has identified risk factors associated with opioid misuse among a trauma surgical patient population, with the highest risk associated with distress-related posttraumatic stress disorder symptoms. A pilot screening tool was created based on this prior research, which was then administered at four trauma surgical units across the state of Wisconsin. Each of the four trauma units successfully implemented the pilot screening tool, and each identified a number of facilitators and barriers to the implementation process. Recommendations for improvement of the implementation process were also gathered. If their recommended changes were to be adopted, trauma providers and trauma unit staff members believed that such a screener for opioid misuse would be a beneficial addition to their current workflow among traumatic injury patients. Future research should refine opioid misuse risk factors and develop a psychometrically sound, validated screener to detect varying levels of risk and tailor treatment approaches based on a patient's risk score. Additionally, future research in the field of opioid misuse prevention should prioritize the recruitment of a more diverse population to support the translation of study findings across populations.

5.
Artículo en Inglés | MEDLINE | ID: mdl-38397653

RESUMEN

Falls and fall-related injuries among older adults are associated with decreased health. Therefore, fall prevention programs (FPPs) are increasingly important. However, the translation of such complex programs into clinical practice lacks insight into factors that influence implementation. Therefore, the aim of this study was to identify how to optimize and further implement a widely used group-based FPP in the Netherlands among participants, therapists and stakeholders using a mixed methods study. FPP participants and therapists filled out a questionnaire about their experiences with the FPP. Moreover, three focus groups were conducted with FPP participants, one with therapists and one with other stakeholders. Data were analysed according to the thematic analysis approach of Braun and Clarke. Overall, 93% of the 104 FPP participants were satisfied with the FPP and 86% (n = 12) of the therapists would recommend the FPP to older adults with balance or mobility difficulties. Moreover, six themes were identified regarding further implementation: (1) recruiting and motivating older adults to participate; (2) structure and content of the program; (3) awareness, confidence and physical effects; (4) training with peers; (5) funding and costs; and (6) long-term continuation. This study resulted in practical recommendations for optimizing and further implementing FPPs in practice.


Asunto(s)
Accidentes por Caídas , Humanos , Anciano , Accidentes por Caídas/prevención & control , Grupos Focales , Costos y Análisis de Costo , Países Bajos
6.
Violence Against Women ; 30(3-4): 953-980, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-37475456

RESUMEN

Intimate partner violence (IPV) remains a global health and human rights problem. This systematic review assesses the effects of preventive interventions on the occurrence of IPV experience or perpetration. Twenty-six studies published between January 1, 2008 and March 31, 2022 were included, contributing 91 effect sizes. Multilevel meta-analysis showed a protective pooled effect (risk ratio = 0.85, 95% CI [0.77, 0.99]). Interventions (also) including men were more effective than interventions for women only. No other moderators were found. Findings underscore that various IPV prevention interventions are now available that can improve the health and rights of women in diverse settings.


Asunto(s)
Violencia de Pareja , Masculino , Humanos , Femenino , Violencia de Pareja/prevención & control , Oportunidad Relativa , Salud Global , Factores de Riesgo
7.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-1017010

RESUMEN

Objective To explore the prevalence rate and related factors of urban and rural residents with hyperuricemia (HUA). Methods A total of 360 subjects in physical examination department of Sanliusan Hospital from January 2020 to January 2023 were selected and divided into urban residents and rural residents according to their permanent residence addresses, and the demographic information, living habits and underlying diseases were collected. Fasting blood glucose (FBG), serum uric acid (SUA), body mass index (BMI) and triglyceride (TG) were measured. The risk factors of HUA were analyzed by logistics regression analysis. Results The incidence rates of HUA in urban and rural residents were 12.18% and 12.88%. There were statistically significant differences in education level, occupation, BMI, sleep time, alcohol drinking, FBG and TG between urban and rural residents (all P24 kg/m2, alcohol drinking and chronic kidney disease were independent risk factors for HUA occurrence among urban residents (all P<0.05). Chronic kidney disease, FBG≥7.0 mmol/L and TG≥2.3 mmol/L were independent risk factors for hyperuricemia occurrence among rural residents (all P<0.05). Conclusion Rural residents should strengthen health education and blood glucose and lipid control, and urban residents should pay more attention to reasonable exercise, control alcohol consumption and reduce HUA occurrence.

8.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-1017048

RESUMEN

Occupational exposure to ionizing radiation represents a critical factor contributing to health risks in workplaces. Previous experimental and clinical studies have demonstrated that ionizing radiation affects human health. Therefore, scientific assessment of health risk caused by ionizing radiation and effective protection against ionizing radiation are of great importance to formulate the preventive interventions against occupational exposure to ionizing radiation. This review summarizes the advances in the research on health effects, health risk assessment methods, and protective interventions of ionizing radiation. We call for research on the health effects of low-dose radiation, individual difference, and optimization of preventive strategies. In addition, improved mechanisms of health monitoring, periodical healthy examinations, and monitoring of radiation doses should be implemented. Moreover, strict compliance to operating procedures and occupational preventive interventions are recommended. These measures aim to minimize the potential harmlessness of occupational exposure to ionizing radiation, thereby safeguarding the health and safety of individuals exposed to ionizing radiation.

9.
Oral Health Prev Dent ; 21(1): 397-406, 2023 Nov 02.
Artículo en Inglés | MEDLINE | ID: mdl-38047638

RESUMEN

PURPOSE: To compare the long-term effects of the Ministry of Public Health's (MOPH) caries preventive interventions for 6- to 12-year-olds (supervised toothbrushing [STB], dental sealant, and combined STB+sealant) to the base case (no intervention) using the System Dynamics Model. MATERIALS AND METHODS: The System Dynamics Model was used to evaluate the intervention scenarios of supervised toothbrushing (STB), sealant, and combined STB+sealant with the base-case scenario. The effectiveness data for the model's interventions were obtained from systematic reviews and meta-analyses. RESULTS: The model determined that the caries-free population increased by 36.2%, 25.5%, and 14.5%, while the caries-affected population decreased by 8.1%, 5.5%, and 3.1% in the combined STB+sealant, sealant, and supervised toothbrushing scenarios compared to the base case at 15 years of age. CONCLUSION: Combined STB+sealant is the most efficacious intervention among those administered to children between the ages of 6 and 12 with permanent teeth. In addition, the System Dynamics Model could be helpful in comparing interventions or policies to determine the optimal intervention for a given population.


Asunto(s)
Susceptibilidad a Caries Dentarias , Caries Dental , Niño , Humanos , Tailandia , Selladores de Fosas y Fisuras/uso terapéutico , Caries Dental/prevención & control , Dentición Permanente
10.
Implement Res Pract ; 4: 26334895231187906, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37790171

RESUMEN

Background: Evidence-based parenting programs effectively prevent the onset and escalation of child and adolescent behavioral health problems. When programs have been taken to scale, declines in the quality of implementation diminish intervention effects. Gold-standard methods of implementation monitoring are cost-prohibitive and impractical in resource-scarce delivery systems. Technological developments using computational linguistics and machine learning offer an opportunity to assess fidelity in a low burden, timely, and comprehensive manner. Methods: In this study, we test two natural language processing (NLP) methods [i.e., Term Frequency-Inverse Document Frequency (TF-IDF) and Bidirectional Encoder Representations from Transformers (BERT)] to assess the delivery of the Family Check-Up 4 Health (FCU4Health) program in a type 2 hybrid effectiveness-implementation trial conducted in primary care settings that serve primarily Latino families. We trained and evaluated models using 116 English and 81 Spanish-language transcripts from the 113 families who initiated FCU4Health services. We evaluated the concurrent validity of the TF-IDF and BERT models using observer ratings of program sessions using the COACH measure of competent adherence. Following the Implementation Cascade model, we assessed predictive validity using multiple indicators of parent engagement, which have been demonstrated to predict improvements in parenting and child outcomes. Results: Both TF-IDF and BERT ratings were significantly associated with observer ratings and engagement outcomes. Using mean squared error, results demonstrated improvement over baseline for observer ratings from a range of 0.83-1.02 to 0.62-0.76, resulting in an average improvement of 24%. Similarly, results demonstrated improvement over baseline for parent engagement indicators from a range of 0.81-27.3 to 0.62-19.50, resulting in an approximate average improvement of 18%. Conclusions: These results demonstrate the potential for NLP methods to assess implementation in evidence-based parenting programs delivered at scale. Future directions are presented. Trial registration: NCT03013309 ClinicalTrials.gov.


Research has shown that evidence-based parenting programs effectively prevent the onset and escalation of child and adolescent behavioral health problems. However, if they are not implemented with fidelity, there is a potential that they will not produce the same effects. Gold-standard methods of implementation monitoring include observations of program sessions. This is expensive and difficult to implement in delivery settings with limited resources. Using data from a trial of the Family Check-Up 4 Health program in primary care settings that served Latino families, we investigated the potential to make use of a form of machine learning called natural language processing (NLP) to monitor program delivery. NLP-based ratings were significantly associated with independent observer ratings of fidelity and participant engagement outcomes. These results demonstrate the potential for NLP methods to monitor implementation in evidence-based parenting programs delivered at scale.

11.
J Family Med Prim Care ; 12(5): 917-924, 2023 May.
Artículo en Inglés | MEDLINE | ID: mdl-37448923

RESUMEN

Aims: Suicide is a major public health problem around the world. The present study aimed to design and determine the effectiveness of a suicide intervention package for psychologists working in the primary health care system in Hormozgan Province. Materials and Methods: This study was conducted in two phases: qualitative and quantitative phases. In the qualitative phase, it was a thematic analysis type, and in the quantitative phase, it was quasi-experimental type with pretest-posttest in two groups of intervention and comparison. To standardize the suicide intervention package, Delphi method was used, and for quantitative content validity, content validity index (CVI) and content validity ratio (CVR) were used. In the quantitative phase of the study, the statistical population of the study included 270 people who had suicidal ideations and had no history of suicide attempt. Among them, 135 people were included in the intervention group and 135 people were included in the comparison group using a convenience sampling method. They were selected among those referred to eight comprehensive rural and urban health service centers in eight cities of Hormozgan Province. The results were analyzed by MANCOVA statistical test. Results: CVR was more than 0.75 and CVI was more than 0.87. In the quantitative phase, the results showed a significant difference between the means before and after the intervention for the variables of psychological distress, suicidal ideation, and hopelessness (P < 0.01). Conclusion: It seems that psychological suicide preventive interventions in the primary health care system are effective in reducing psychological distress,suicidal thoughts and hopelessness.

12.
Trials ; 24(1): 291, 2023 Apr 22.
Artículo en Inglés | MEDLINE | ID: mdl-37087437

RESUMEN

BACKGROUND: Children of parents with mental illness have an increased risk of developing mental illness themselves throughout their lifespan. This is due to genetic factors but also environmental disadvantages during childhood associated with parental mental illness. Selective primary preventive interventions for the children are recommended to mitigate risk factors and strengthen protective factors, but large-scale, longitudinal studies are needed. This study aims to investigate the effect of the Family Talk Preventive Intervention in a cohort of children and their parents with mental illness. METHODS: The study is a randomized controlled trial with 286 planned families with at least one parent with any mental illness and at least one child aged 7 to 17 years. It will be carried out in the mental healthcare system in the Capital Region of Denmark. Families will be referred from hospitals and municipalities. The children and parents will be assessed at baseline and then randomized and allocated to either the Family Talk Preventive Intervention or service as usual. The intervention group will be assigned to Family Talk Preventive Intervention, a manualized programme consisting of ~ seven sessions for the family, including psychoeducation about parental mental illness and resilience in children, stimulating dialogue between family members and creating a common family narrative. The study period for both groups will be 12 months. Follow-up assessments will be conducted after 4 months and 12 months. The primary outcomes are the children's level of functioning, parental sense of competence and family functioning. DISCUSSION: Given the prevalence of transgenerational transmission of mental illness, a systematic approach to prevention is needed in the mental healthcare setting. This study provides valuable knowledge on the Family Talk Preventive Intervention with a large sample size, inclusion of any parental mental illness and examination of the primary outcomes. TRIAL REGISTRATION: ClinicalTrials.gov NCT05615324. Registered on 26 October 2022. Retrospectively registered.


Asunto(s)
Trastornos Mentales , Responsabilidad Parental , Niño , Humanos , Padres , Trastornos Mentales/diagnóstico , Trastornos Mentales/prevención & control , Conducta Infantil , Factores de Riesgo , Ensayos Clínicos Controlados Aleatorios como Asunto
13.
Public Health ; 218: 53-59, 2023 May.
Artículo en Inglés | MEDLINE | ID: mdl-36965464

RESUMEN

INTRODUCTION: Emotional education programmes are universal preventive strategies for health promotion, especially mental health. The aim of this study is to evaluate the effectiveness and implementation of '1,2,3, emoció!': a preschool-based programme designed to improve emotional competence and targeted to 3-5-year-old children in Barcelona during three academic years. STUDY DESIGN: Cluster randomised trial, using schools as clusters. METHODS: The study's population included preschoolers 3-5 years old from Barcelona. Teachers offered the programme during one or three academic years in the intervention groups. We evaluated the emotional competence of each child at the beginning and the end of the academic year with the Emotional Competence Assessment Questionnaire (30-180 scale). We studied the implementation process and analysed the outcomes with nested linear regression models. Considering sociodemographic variables and implementation outcomes, we obtained the individual differences in emotional competence at the end of the school year-segregated by sex-for intervention and comparison groups. RESULTS: 1586 children participated in the study. The emotional competence level increased significantly after one year (4.1 in boys; 5.6 in girls; P < 0.05) and after three years of intervention (5.5 in boys; 8.0 in girls; P < 0.01), compared to comparison group. The level of emotional competence was the highest for the 3-year intervention group: we obtained an average ECAQ score of 131.1 (95% CI 126.9-135.2) for boys and 141 (95% CI 137.2-144.9) for girls. We observed that an accurate implementation improved its results. CONCLUSIONS: The programme '1,2,3, emoció!' effectively increases preschool children's emotional competence, especially when the programme is rigorously implemented for three years.


Asunto(s)
Promoción de la Salud , Instituciones Académicas , Masculino , Femenino , Humanos , Preescolar , Escolaridad , Cognición , Salud Mental
14.
BMC Psychiatry ; 23(1): 102, 2023 02 10.
Artículo en Inglés | MEDLINE | ID: mdl-36765312

RESUMEN

BACKGROUND: Children of parents with post-traumatic stress disorder (PTSD) are at increased risk of adverse psychological outcomes. An important risk mechanism is impaired parental functioning, including negative parenting behavior, perceived incompetence, and lack of social support. Several parenting interventions for trauma-exposed parents and parents with psychiatric disorders exist, but none have specifically targeted parents with PTSD. Our objective is to evaluate the effectiveness of a blended care preventive parenting intervention for parents with PTSD. METHODS: The intervention was adapted from an existing online intervention, KopOpOuders Self-Help. In co-creation with parents with PTSD and partners, the intervention was adapted into KopOpOuders-PTSD, by adding PTSD-specific content and three in-person-sessions with a mental health prevention professional. Effectiveness will be tested in a randomized controlled trial among N = 142 parents being treated for PTSD at Arkin Mental Health Care (control condition: treatment as usual, n = 71; intervention condition: treatment as usual + intervention, n = 71). Online questionnaires at pretest, posttest, and three-month follow-up and ecological momentary assessment at pretest and posttest will be used. Intervention effects on primary (parenting behavior) and secondary outcomes (perceived parenting competence, parental social support, parenting stress, child overall psychological problems and PTSD symptoms) will be analyzed using generalized linear mixed modeling. We will also analyze possible moderation effects of parental PTSD symptoms at pretest on primary and secondary outcomes. DISCUSSION: This study protocol describes the randomized controlled trial of KopOpOuders-PTSD, a blended care preventive parenting intervention for parents with PTSD. Findings can contribute to understanding of the effectiveness of parenting support in clinical practice for PTSD. TRIAL REGISTRATION: This protocol (Version 1) was registered on 11-02-2022 at ClinicalTrials.gov under identification number NCT05237999.


Asunto(s)
Responsabilidad Parental , Trastornos por Estrés Postraumático , Niño , Humanos , Responsabilidad Parental/psicología , Trastornos por Estrés Postraumático/prevención & control , Relaciones Padres-Hijo , Padres/psicología , Salud Mental , Ensayos Clínicos Controlados Aleatorios como Asunto
15.
Prog Retin Eye Res ; 97: 101158, 2023 11.
Artículo en Inglés | MEDLINE | ID: mdl-36621380

RESUMEN

Rhegmatogenous retinal detachment (RRD) is a sight threatening condition that warrants immediate surgical intervention. To date, 29 genes have been associated with monogenic disorders involving RRD. In addition, RRD can occur as a multifactorial disease through a combined effect of multiple genetic variants and non-genetic risk factors. In this review, we provide a comprehensive overview of the spectrum of hereditary disorders involving RRD. We discuss genotype-phenotype correlations of these monogenic disorders, and describe genetic variants associated with RRD through multifactorial inheritance. Furthermore, we evaluate our current understanding of the molecular disease mechanisms of RRD-associated genetic variants on collagen proteins, proteoglycan versican, and the TGF-ß pathway. Finally, we review the role of genetics in patient management and prevention of RRD. We provide recommendations for genetic testing and prophylaxis of at-risk patients, and hypothesize on novel therapeutic approaches beyond surgical intervention.


Asunto(s)
Desprendimiento de Retina , Humanos , Desprendimiento de Retina/genética , Agudeza Visual , Estudios de Asociación Genética
16.
Prev Sci ; 24(4): 715-727, 2023 05.
Artículo en Inglés | MEDLINE | ID: mdl-36595131

RESUMEN

The effect of the Adapted-Coping with Stress (A-CWS) intervention on social support coping was examined, using a randomized controlled trial design. The participants were 410 ninth-grade students (ages 14 to 16 years and mostly African American) living in low-resourced neighborhoods. Participants were randomly assigned 1:1 to either the A-CWS intervention or a standard care control condition. All participants were assessed at their schools before implementation of the intervention, at intervention completion, and again at 6- and 12-month post-intervention. Engagement in social support coping was examined in both intention-to-treat and treatment-as-received samples (i.e., intervention participants who attended at least 12 A-CWS treatment sessions and participants in the standard care control condition), using latent growth models. In intention-to-treat analyses, no significant treatment effects were identified. In treatment-as-received analyses, results revealed a significant association between social support coping and treatment condition; levels of social support coping decreased over time in the control condition, but they remained relatively stable in the treatment condition. The results indicate adequate intervention adherence and efficacy of the A-CWS to sustain social support coping within a sample of youth at high risk for stress exposure and associated disorders.Clinical Trial Registration: clinicaltrials.gov identifier: NCT0395445.


Asunto(s)
Negro o Afroamericano , Apoyo Social , Humanos , Adolescente , Adaptación Psicológica , Estudiantes
17.
Child Psychiatry Hum Dev ; 54(5): 1373-1385, 2023 10.
Artículo en Inglés | MEDLINE | ID: mdl-35303199

RESUMEN

Engagement in mental health-focused preventive interventions is understudied. Demographic, child, and system-level predictors of engagement were explored in a study with children in foster care (N = 222, Mage = 10.3) who participated in a 30-week intervention. Attendance and engagement in mentor visits and skills groups were rated weekly. Only 4 of 21 predictors showed bivariate associations with attendance/engagement: child sex, IQ, behavior problems, and trauma symptoms. SEM models with these three variables and a measure of adverse childhood experience (ACEs), were used to develop a model of engagement. Males had poorer mentor visit and group engagement. Group attendance was positively associated with trauma symptoms and negatively associated with ACEs. Group engagement was associated with higher IQ and fewer behavior problems. A contextually-sensitive intervention can result in high engagement for a vulnerable and diverse population, yet a few child factors still impacted engagement, and when identified could be ameliorated.Trial Registration ClinicalTrials.gov, Identifiers: NCT00809315 & NCT00810056.


Asunto(s)
Experiencias Adversas de la Infancia , Maltrato a los Niños , Niño , Humanos , Masculino , Cuidados en el Hogar de Adopción , Salud Mental
18.
Prev Sci ; 24(2): 299-303, 2023 02.
Artículo en Inglés | MEDLINE | ID: mdl-36418802

RESUMEN

Developing a better understanding of sources and mechanisms of heterogeneity is a key route to improving outcomes and targeting of preventive interventions. This commentary attempts to draw together findings from eight intervention trials in this special issue, each exploring baseline target moderation (BTM) or baseline target moderated mediation (BTMM). It considers their implications for prevention research and program design, particularly the question of whether they can help us to revise or adapt interventions. The studies cover a range of interventions, targets, and contexts, including parenting, couple, and CBT interventions, for depression, anxiety, conduct problems, or obesity. Some important findings stand out. Where studies found moderator effects, they tended to operate in a "compensatory" fashion, such that greater benefit was found in higher risk groups, suggesting that closer targeting might be warranted. It was rare for harmful effects to be detected for any subgroups. In other respects, patterns of BTM/BTMM findings were quite mixed across studies, suggesting it would be premature to change our interventions based on these trials. Implications of the findings for equity, for "slimming down" and scaling up interventions, and for research are discussed, including the need to combine BTMM with intervention component research, and to accumulate a more robust body of evidence by pooling data across trials.


Asunto(s)
Responsabilidad Parental , Problema de Conducta , Humanos , Proyectos de Investigación , Ansiedad , Trastornos de Ansiedad
19.
Contemp Clin Trials ; 125: 107049, 2023 02.
Artículo en Inglés | MEDLINE | ID: mdl-36521631

RESUMEN

BACKGROUND: Concerns about the rise in adolescent vaping and cannabis use suggest the need for effective substance use prevention programs. Botvin LifeSkills Training (LST) has a strong evidence base at the middle school level for preventing or reducing tobacco use and related problems. A high school (grades 9-10) version of the LST program was also developed and shows promising initial evidence for reducing tobacco use in a single pilot study. However, the high school version of LST has not been sufficiently tested in an experimental trial, despite being widely implemented in high schools across the U.S. This paper outlines the study protocol for a large-scale cluster randomized trial of Botvin High School LST, with objectives of documenting the design of prospective research and promoting transparency. METHODS: A total of 60 high schools in Colorado and Ohio were randomized to the 10-session, teacher-led intervention group (n = 33 schools) or business-as-usual control group (n = 27 schools). Across two cohorts of schools, 9th-grade students complete self-report surveys at pretest, immediate posttest, 1-year follow-up, and 21-month follow-up. Primary outcomes are tobacco (nicotine) use and cannabis use. Secondary outcomes are alcohol use, illicit drug use, psychosocial behaviors (e.g., violence and mental health), and academic achievement. Intent-to-treat analyses will use multilevel modeling to estimate intervention effects across assessment points. CONCLUSION: This independent evaluation will help to determine whether the intervention is appropriate for large-scale adoption. This trial is preregistered with the Open Science Framework (https://osf.io/dnz5q/).


Asunto(s)
Instituciones Académicas , Trastornos Relacionados con Sustancias , Humanos , Adolescente , Proyectos Piloto , Estudios Prospectivos , Trastornos Relacionados con Sustancias/prevención & control , Estudiantes/psicología , Servicios de Salud Escolar , Ensayos Clínicos Controlados Aleatorios como Asunto
20.
Interv. psicosoc. (Internet) ; 31(3): 177-184, septiembre 2022. tab, graf
Artículo en Inglés | IBECS | ID: ibc-210532

RESUMEN

Sexual abuse of adolescents by adults on the Internet is a severe risk with negative consequences for the victims. However, there is an important gap in the development of preventive interventions to address this problem. This study evaluated the efficacy of a brief (less than one hour) educational intervention on online grooming (less than one hour) in reducing adolescents’ sexual interaction behaviors with adults when they are sexually solicited. A sample of 856 Spanish adolescents (48% girls, ages 11-17 years) was randomized into two intervention conditions (educational intervention about online grooming and a resilience control intervention). Adolescents completed measures of online sexual solicitation by adults and sexualized interactions with adults at pretest and at three- and six-month follow-ups. Measures of their knowledge about online grooming were taken at pretest, postintervention, and at three- and six-month follow-ups. The results of multilevel analyses indicated that the intervention reduced sexualized interactions when adolescents were sexually solicited by adults (β = -.16, SD = .07, t = -2.44, p = .015). Moreover, the intervention increased adolescents’ knowledge about online grooming over time (β = 1.95, SD = .19, t = 10.52, p < .001). These findings suggest that a brief educational intervention about online grooming may be a promising, low-cost intervention to reduce the risks of sexual abuse on the Internet. (AU)


El abuso sexual de adolescentes por parte de adultos en Internet (grooming online) es un riesgo grave con consecuencias negativas para las víctimas. Sin embargo, existe un importante vacío en el desarrollo de intervenciones preventivas para abordar este problema. Este estudio evalúa la eficacia de una intervención educativa breve (menos de una hora) sobre el grooming online para disminuir las conductas de interacción sexual de los adolescentes con adultos cuando son solicitados sexualmente. Una muestra de 856 adolescentes españoles (48% chicas; edades entre 11 y 17 años) fue aleatorizada en dos condiciones de intervención (intervención educativa sobre el grooming online y una intervención control de resiliencia). A los adolescentes se les aplicaron medidas de solicitud sexual online por parte de adultos e interacciones sexualizadas con adultos en la línea base y en los seguimientos a tres y seis meses. Además, se tomaron medidas sobre conocimiento del grooming online en la línea base, después de la intervención y en los seguimientos a tres y seis meses. Los resultados de los análisis multinivel indicaron que la intervención redujo las interacciones sexualizadas cuando los adolescentes eran solicitados sexualmente por adultos (β = -.16, SD = .07, t = -2.44, p = .015). Por otra parte, la intervención aumentó los conocimientos de los adolescentes sobre grooming online a lo largo del tiempo (β = 1.95, SD = .19, t = 10.52, p < .001). Estos resultados sugieren que una breve intervención educativa sobre grooming online puede ser prometedora y de bajo coste para reducir los riesgos de abuso sexual en Internet. (AU)


Asunto(s)
Humanos , Delitos Sexuales , Internet , Análisis Multinivel , Adolescente
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA