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1.
Sci Rep ; 14(1): 21202, 2024 Sep 11.
Artículo en Inglés | MEDLINE | ID: mdl-39261606

RESUMEN

The blockage and the deformation and failure of the ore pass walls constitute two major problems in applying the ore passes in mines. These problems, which affect the normal operation of mine production, have attracted widespread attention worldwide. The labeled-particle layers method based on numerical simulation was used to investigate the flow characteristics of the ore-rock bulk in the ore pass under different eccentric distances of the ore-drawing port center and ore pass centerline. Moreover, the overpressure coefficient and overpressure number are used to evaluate the degree of damage to the ore-pass wall. The results show that: (1) During the ore drawing process under different eccentricities, the flow patterns of the topmost labeled-particle layers in the ore pass are always in a "-" shaped distribution, and the other layers in the ore pass gradually transition from a "-" shape to a "U" shaped distribution, and then gradually to a "V" shape closer to the drawing funnel; (2) in the range of the ore-drawing funnel, the flow pattern of the ore-rock bulk gradually changes from an upright "V" shape to an italic "V" shape with increasing eccentricity and tip slants to the drawing port, and is less affected in the shaft; and (3) the dynamic lateral pressure caused by the ore-rock flow mainly acts on the lower part of the storage section. When the eccentricity is 0.5 m, the maximum overpressure coefficient and overpressure times are the smallest, leading to the lowest damage degree of the ore pass wall.

2.
Front Bioeng Biotechnol ; 12: 1455324, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39280344

RESUMEN

Introduction: Shock wave overpressure exposures can result in blast-induced traumatic brain injury (bTBI) in warfighters. Although combat helmets provide protection against blunt impacts, the protection against blast waves is limited due to the observed high overpressures occurring underneath the helmet. One route to enhance these helmets is by incorporating viscoelastic materials into the helmet designs, reducing pressures imposed on the head. This study aims to further investigate this mitigation technique against under-helmet overpressures by adding a viscoelastic liner to the inside of a combat helmet. Methods: The liner's effectiveness was evaluated by exposing it to free-field blasts of Composition C-4 at overpressures ranging from 27.5 to 165 kPa (4 - 24 psi) and comparing shock waveform parameters to an unlined helmet. Blasts were conducted using an instrumented manikin equipped with and without a helmet and then with a helmet modified to incorporate a viscoelastic liner. Evaluation of blast exposure results focused on the waveform parameters of peak pressure, impulse and positive phase duration. Results: The results show that peak overpressure was higher when wearing a helmet compared to not wearing a helmet. However, the helmet with the viscoelastic liner reduced the average peak overpressures compared to the helmet alone. For the lowest overpressure tested, 27.5 kPa, the helmet liner decreased the overpressure on the top of the head by 37.6%, with reduction reaching 26% at the highest overpressure exposure of 165 kPa. Additionally, the inclusion of the viscoelastic material extended the shock waveforms' duration, reducing the rate the shock wave was applied to the head. The results of this study show the role a helmet and helmet design play in the level of blast exposure imposed on a wearer. The testing and evaluation of these materials hold promise for enhancing helmet design to better protect against bTBI.

3.
Sci Rep ; 14(1): 18671, 2024 08 12.
Artículo en Inglés | MEDLINE | ID: mdl-39134580

RESUMEN

Ventilation systems of operating rooms (ORs) are significantly important in preventing postoperative wound infections that can cause morbidity and mortality after surgery in or out of the hospital. This study aims to identify the optimum overpressure for efficient operation while reducing the risk of surgical site infections (SSIs) based on the actual OR with the help of computational fluid dynamics. The species transport model, Lagrangian discrete phase model, and turbulent standard k- ε model are mainly used for the transient numerical study to improve the performance of the OR and reduce SSI cases. Four OR schemes were initially calculated for the best location of the patient on the surgical table. The results revealed that the modified position 90˚ is the best location with the minimum CO2 and BCP concentrations. The investigated operating room could host up to ten surgical members with the optimum overpressure of 5.89 Pa and 0.56 m/s of supply velocity under the standard cleanliness level. Modifying the supply surface area will enhance the performance of the operating room by providing a cleaner zone and maintaining the desired room pressure, even with a low airflow rate. This optimization scheme could guide practical applications in all positively pressurized operating rooms to address issues related to overpressure effects.


Asunto(s)
Quirófanos , Infección de la Herida Quirúrgica , Ventilación , Ventilación/métodos , Humanos , Infección de la Herida Quirúrgica/prevención & control , Presión , Modelos Teóricos , Hidrodinámica
4.
Environ Sci Pollut Res Int ; 31(25): 37835-37847, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38789706

RESUMEN

In a semi-closed visualization pipeline, this experiment studied the inhibitory effect of ultra-fine pure water mist, ultra-fine water mist containing inorganic salt and ultra-fine water mist containing bacteria-inorganic salt on 9.8% methane explosion under five different quality of spray volume. Combined with the methane explosion suppression experiment, the ability of methane-oxidizing bacteria to degrade 9.8% of methane was studied in a simulated pipeline. Experiments showed that the addition of inorganic salt and the degradation of methane-oxidizing bacteria could improve the suppression explosion effect of ultra-fine water mist, and the suppression explosion effect was related to the volume of water mist. Under the same ultra-fine water mist condition, with the increase of the volume of water mist, the explosion suppression effect was improved. Compared with pure methane, pure water ultra-fine water mist, and inorganic salt ultra-fine water mist, the maximum explosion overpressure and flame propagation speed under the condition of bacteria-inorganic salt ultra-fine water mist were significantly reduced. Compared with the explosion of pure methane, due to the degradation of methane by methane-oxidizing bacteria, when the degradation time was 10 h, and the volume of ultra-fine water mist containing bacteria-inorganic salt was 12.5 mL, the maximum explosion overpressure dropped significantly from 0.663 to 0.343 MPa, a decrease of 48.27%. The appearance time of the maximum explosion overpressure was delayed from 208.8 to 222.6 ms. The peak flame velocity was 4 m s-1, which was 83.3% lower than that of 9.8% pure methane explosion. This study will contribute to the development of efficient ultrafine water mist synergistic inhibitors for the prevention of methane explosion disasters.


Asunto(s)
Bacterias , Metano , Bacterias/metabolismo , Explosiones , Agua/química , Biodegradación Ambiental
5.
Proc Natl Acad Sci U S A ; 121(19): e2313568121, 2024 May 07.
Artículo en Inglés | MEDLINE | ID: mdl-38648470

RESUMEN

United States (US) Special Operations Forces (SOF) are frequently exposed to explosive blasts in training and combat, but the effects of repeated blast exposure (RBE) on SOF brain health are incompletely understood. Furthermore, there is no diagnostic test to detect brain injury from RBE. As a result, SOF personnel may experience cognitive, physical, and psychological symptoms for which the cause is never identified, and they may return to training or combat during a period of brain vulnerability. In 30 active-duty US SOF, we assessed the relationship between cumulative blast exposure and cognitive performance, psychological health, physical symptoms, blood proteomics, and neuroimaging measures (Connectome structural and diffusion MRI, 7 Tesla functional MRI, [11C]PBR28 translocator protein [TSPO] positron emission tomography [PET]-MRI, and [18F]MK6240 tau PET-MRI), adjusting for age, combat exposure, and blunt head trauma. Higher blast exposure was associated with increased cortical thickness in the left rostral anterior cingulate cortex (rACC), a finding that remained significant after multiple comparison correction. In uncorrected analyses, higher blast exposure was associated with worse health-related quality of life, decreased functional connectivity in the executive control network, decreased TSPO signal in the right rACC, and increased cortical thickness in the right rACC, right insula, and right medial orbitofrontal cortex-nodes of the executive control, salience, and default mode networks. These observations suggest that the rACC may be susceptible to blast overpressure and that a multimodal, network-based diagnostic approach has the potential to detect brain injury associated with RBE in active-duty SOF.


Asunto(s)
Traumatismos por Explosión , Personal Militar , Humanos , Traumatismos por Explosión/diagnóstico por imagen , Adulto , Masculino , Estados Unidos , Imagen por Resonancia Magnética , Femenino , Tomografía de Emisión de Positrones , Cognición/fisiología , Encéfalo/diagnóstico por imagen , Encéfalo/metabolismo , Adulto Joven
6.
Sensors (Basel) ; 24(6)2024 Mar 14.
Artículo en Inglés | MEDLINE | ID: mdl-38544124

RESUMEN

The measurement process of ground shock wave overpressure is influenced by complex field conditions, leading to notable errors in peak measurements. This study introduces a novel pressure measurement model that utilizes the Rankine-Hugoniot relation and an equilateral ternary array. The research delves into examining the influence of three key parameters (array size, shock wave incidence angle, and velocity) on the precision of pressure measurement through detailed simulations. The accuracy is compared with that of a dual-sensor array under the same conditions. Static explosion tests were conducted using bare charges of 0.3 kg and 3 kg TNT to verify the numerical simulation results. The findings indicate that the equilateral ternary array shock wave pressure measurement method demonstrates a strong anti-interference capability. It effectively reduces the peak overpressure error measured directly by the shock wave pressure sensor from 17.73% to 1.25% in the test environment. Furthermore, this method allows for velocity-based measurement of shock wave overpressure peaks in all propagation direction, with a maximum measurement error of 3.59% for shock wave overpressure peaks ≤ 9.08 MPa.

7.
Proc Natl Acad Sci U S A ; 121(8): e2312152121, 2024 Feb 20.
Artículo en Inglés | MEDLINE | ID: mdl-38346195

RESUMEN

Subsurface sandstone reservoirs sealed by overlying, low-permeability layers provide capacity for long-term sequestration of anthropogenic waste. Leakage can occur if reservoir pressures rise sufficiently to fracture the seal. Such pressures can be generated within the reservoir by vigorous injection of waste or, over thousands of years, by natural processes. In either case, the precise role of intercalated mudstones in the long-term evolution of reservoir pressure remains unclear; these layers have variously been viewed as seals, as pressure sinks, or as pressure sources. Here, we use the geological record of episodic fluid venting in the Levant Basin to provide striking evidence for the pressure-source hypothesis. We use a Bayesian framework to combine recently published venting data, which record critical subsurface pressures since ∼2 Ma, with a stochastic model of pressure evolution to infer a pressure-recharge rate of ∼30 MPa/Myr. To explain this large rate, we quantify and compare a range of candidate mechanisms. We find that poroelastic pressure diffusion from mudstones provides the most plausible explanation for these observations, amplifying the ∼3 MPa/Myr recharge caused primarily by tectonic compression. Since pressurized mudstones are ubiquitous in sedimentary basins, pressure diffusion from mudstones is likely to promote seal failure globally.

8.
Int J Mol Sci ; 25(1)2024 Jan 04.
Artículo en Inglés | MEDLINE | ID: mdl-38203813

RESUMEN

Low-level blast (LLB) exposure can lead to alterations in neurological health, cerebral vasculature, and cerebral blood flow (CBF). The development of cognitive issues and behavioral abnormalities after LLB, or subconcussive blast exposure, is insidious due to the lack of acute symptoms. One major hallmark of LLB exposure is the initiation of neurovascular damage followed by the development of neurovascular dysfunction. Preclinical studies of LLB exposure demonstrate impairment to cerebral vasculature and the blood-brain barrier (BBB) at both early and long-term stages following LLB. Neuroimaging techniques, such as arterial spin labeling (ASL) using magnetic resonance imaging (MRI), have been utilized in clinical investigations to understand brain perfusion and CBF changes in response to cumulative LLB exposure. In this review, we summarize neuroimaging techniques that can further our understanding of the underlying mechanisms of blast-related neurotrauma, specifically after LLB. Neuroimaging related to cerebrovascular function can contribute to improved diagnostic and therapeutic strategies for LLB. As these same imaging modalities can capture the effects of LLB exposure in animal models, neuroimaging can serve as a gap-bridging diagnostic tool that permits a more extensive exploration of potential relationships between blast-induced changes in CBF and neurovascular health. Future research directions are suggested, including investigating chronic LLB effects on cerebral perfusion, exploring mechanisms of dysautoregulation after LLB, and measuring cerebrovascular reactivity (CVR) in preclinical LLB models.


Asunto(s)
Circulación Cerebrovascular , Neuroimagen , Animales , Arterias , Barrera Hematoencefálica/diagnóstico por imagen , Encéfalo/diagnóstico por imagen
9.
Materials (Basel) ; 16(24)2023 Dec 11.
Artículo en Inglés | MEDLINE | ID: mdl-38138744

RESUMEN

A self-built gas explosion testing platform was used to explore the quenching effect of flame-retardant polyurethane foam on a gas explosion. The effect of the foam's filling position and length on the explosion suppression performance was explored. The results demonstrate that polyurethane foam exhibits an excellent flame-quenching performance, with a minimum of a 5 cm length of porous material being sufficient to completely quench the flame during propagation. Furthermore, the attenuation function of this porous material on the pressure wave is insignificantly affected by the change in ignition energy. Compared with the explosive state of the empty pipeline, the best suppression effect is obtained when the polyurethane foam is 20 cm in length with a filling position at 1.8 m, and the maximum explosion pressure and maximum rise rate are attenuated by 86.2% and 84.7%, respectively. This work has practical significance for the application of porous materials in explosion suppression and explosion-proof technologies in the chemical industrial processing and oil (gas) storage fields.

10.
J Spec Oper Med ; 23(4): 47-56, 2023 Dec 29.
Artículo en Inglés | MEDLINE | ID: mdl-37851859

RESUMEN

United States Special Operations Forces (SOF) personnel are frequently exposed to explosive blasts in training and combat. However, the effects of repeated blast exposure on the human brain are incompletely understood. Moreover, there is currently no diagnostic test to detect repeated blast brain injury (rBBI). In this "Human Performance Optimization" article, we discuss how the development and implementation of a reliable diagnostic test for rBBI has the potential to promote SOF brain health, combat readiness, and quality of life.


Asunto(s)
Traumatismos por Explosión , Personal Militar , Humanos , Estados Unidos , Calidad de Vida , Encéfalo/diagnóstico por imagen , Traumatismos por Explosión/diagnóstico , Traumatismos por Explosión/terapia , Explosiones
11.
Medicina (Kaunas) ; 59(9)2023 Sep 18.
Artículo en Inglés | MEDLINE | ID: mdl-37763802

RESUMEN

Background and Objectives: Epidemiological data indicate that blast exposure is the most common morbidity responsible for mild TBI among Service Members (SMs) during recent military operations. Blast-induced tinnitus is a comorbidity frequently reported by veterans, and despite its wide prevalence, it is also one of the least understood. Tinnitus arising from blast exposure is usually associated with direct structural damage that results in a conductive and sensorineural impairment in the auditory system. Tinnitus is also believed to be initiated by abnormal neuronal activities and temporal changes in neuroplasticity. Clinically, it is observed that tinnitus is frequently accompanied by sleep disruption as well as increased anxiety. In this study, we elucidated some of the mechanistic aspects of sensorineural injury caused by exposure to both shock waves and impulsive noise. The isolated conductive auditory damage hypothesis was minimized by employing an animal model wherein both ears were protected. Materials and Methods: After the exposure, the animals' hearing circuitry status was evaluated via acoustic startle response (ASR) to distinguish between hearing loss and tinnitus. We also compared the blast-induced tinnitus against the well-established sodium salicylate-induced tinnitus model as the positive control. The state of the sensorineural auditory system was evaluated by auditory brainstem response (ABR), and this test helped examine the neuronal circuits between the cochlea and inferior colliculus. We then further evaluated the role of the excitatory and inhibitory neurotransmitter receptors and neuronal synapses in the auditory cortex (AC) injury after blast exposure. Results: We observed sustained elevated ABR thresholds in animals exposed to blast shock waves, while only transient ABR threshold shifts were observed in the impulsive noise group solely at the acute time point. These changes were in concert with the increased expression of ribbon synapses, which is suggestive of neuroinflammation and cellular energy metabolic disorder. It was also found that the onset of tinnitus was accompanied by anxiety, depression-like symptoms, and altered sleep patterns. By comparing the effects of shock wave exposure and impulsive noise exposure, we unveiled that the shock wave exerted more significant effects on tinnitus induction and sensorineural impairments when compared to impulsive noise. Conclusions: In this study, we systematically studied the auditory system structural and functional changes after blast injury, providing more significant insights into the pathophysiology of blast-induced tinnitus.


Asunto(s)
Sordera , Acúfeno , Animales , Acúfeno/etiología , Reflejo de Sobresalto , Ansiedad , Trastornos de Ansiedad
12.
Comput Methods Programs Biomed ; 242: 107786, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-37716221

RESUMEN

The intense impulse noise may damage the soldiers' hearing organs during a weapon's firing. It is essential to find out the generation mechanism of the overpressure at the bottom of the ear. The experiments of measuring the overpressure at the bottom of the ear were conducted through a rotating human head model at a recoilless weapon firing platform. The results showed that the overpressure peak at the bottom of the ear decreases with the increasing incident angle. A simulation of the test condition was developed based on the plane shock wave method. The finite element model was verified reasonably compared to the test results. The Friedlander wave propagating to the ear canal was implemented at different incident angles. The generation of the overpressure at the bottom of the ear was analyzed. According to the pressure nephograms, the impulse noise stagnated at the bottom of the ear, so the overpressure was the total pressure of impulse noise. Two parts of impulse noise entered the canal successively due to the influence of the pinna. The overpressure and Mach number at the entrance of the ear canal both decreased with increasing incident angles, resulting in impulse noise superimposed at the bottom of the ear. Investigating the generation of overpressure at the bottom of the ear under varying incident angles may have important reference value for analyzing and preventing auditory organ damage caused by impulse noise.


Asunto(s)
Audición , Humanos , Análisis de Elementos Finitos
13.
Heliyon ; 9(8): e18803, 2023 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-37609431

RESUMEN

The effect of flexible obstacles with varying thicknesses on the explosion characteristics of combustible gas in a simulated confined duct (cross section 80 mm × 80 mm, length 3 m) was experimentally investigated, aiming to reduce the huge losses caused by gas explosion accidents in the process industries and mining industries. In this paper, plant fiber membranes with an opening area of 0 and thicknesses of 0.105 mm, 0.210 mm, 0.315 mm, 0.420 mm, 0.525 mm, and 0.630 mm were selected as flexible obstacles. The thickness of the flexible obstacle determines the strength of its compressive resistance. The characteristics of overpressure and flame during methane explosions are analyzed and conclusions are drawn. Results indicate that several shock wave reflection processes occur before the diaphragm ruptures, resulting in turbulent flames. In addition, the explosion wave generated numerous shock reflections during the rupture process of the diaphragm, which was gradually discharged downstream of the pipe by ejection as the pressure wave accumulated in front of the diaphragm. It should be noted that the thickness of the flexible obstacle determines the pressure accumulation in front of the membrane. Generally, the thinner the flexible obstacle, the less intense the turbulent flame is induced by the flexible obstacle, decreasing the contact area between the unignited gas downstream of the pipeline and the turbulent flame area. In conclusion, with an increase in the thickness of the flexible barrier, it exhibits a mechanism of initially suppressing and subsequently enhancing the impact on methane explosions. The increase of the thickness of the flexible obstacle motivates the flame propagation speed, which leads to an increase of turbulence intensity and explosion intensity.

14.
Sensors (Basel) ; 23(10)2023 May 14.
Artículo en Inglés | MEDLINE | ID: mdl-37430656

RESUMEN

Shock tubes can carry out dynamic mechanical impact tests on civil engineering structures. The current shock tubes mostly use an explosion with aggregate charge to obtain shock waves. Limited effort has been made to study the overpressure field in shock tubes with multi-point initiation. In this paper, the overpressure fields in a shock tube under the conditions of single-point initiation, multi-point simultaneous initiation, and multi-point delayed initiation have been analyzed by combining experiments and numerical simulations. The numerical results match well with the experimental data, which indicates that the computational model and method used can accurately simulate the blast flow field in a shock tube. For the same charge mass, the peak overpressure at the exit of the shock tube with the multi-point simultaneous initiation is smaller than that with single-point initiation. As the shock waves are focused on the wall, the maximum overpressure on the wall of the explosion chamber near the explosion zone is not reduced. The maximum overpressure on the wall of the explosion chamber can be effectively reduced by a six-point delayed initiation. When the interval time is less than 10 ms, the peak overpressure at the nozzle outlet decreases linearly with the interval of the explosion. When the interval time is greater than 10 ms, the overpressure peak remains unchanged.

15.
Front Neurol ; 14: 1175671, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37305738

RESUMEN

CONQUER is a pilot blast monitoring program that monitors, quantifies, and reports to military units the training-related blast overpressure exposure of their service members. Overpressure exposure data are collected using the BlackBox Biometrics (B3) Blast Gauge System (BGS, generation 7) sensors mounted on the body during training. To date, the CONQUER program has recorded 450,000 gauge triggers on monitored service members. The subset of data presented here has been collected from 202 service members undergoing training with explosive breaching charges, shoulder-fired weapons, artillery, mortars, and 0.50 caliber guns. Over 12,000 waveforms were recorded by the sensors worn by these subjects. A maximum peak overpressure of 90.3 kPa (13.1 psi) was recorded during shoulder-fired weapon training. The largest overpressure impulse (a measure of blast energy) was 82.0 kPa-ms (11.9 psi-ms) and it was recorded during explosive breaching with a large wall charge. Operators of 0.50 caliber machine guns have the lowest peak overpressure impulse (as low as 0.62 kPa-ms or 0.09 psi-ms) of the blast sources considered. The data provides information on the accumulation of blast overpressure on service members over an extended period of time. The cumulative peak overpressure, peak overpressure impulse, or timing between exposures is all available in the exposure data.

16.
J Neurotrauma ; 2023 Jul 21.
Artículo en Inglés | MEDLINE | ID: mdl-37279302

RESUMEN

Blast-induced traumatic brain injury (bTBI) has been identified as the signature injury of Operation Iraqi Freedom and Operation Enduring Freedom. Although the incidence of bTBI increased significantly after the introduction of improvised explosive devices, the mechanism of the injury is still uncertain, which is negatively impacting the development of suitable countermeasures. Identification of suitable biomarkers that could aid in the proper diagnosis of and prognosis for both acute and chronic bTBI is essential since bTBI frequently is occult and may not be associated with overtly detectable injuries to the head. Lysophosphatidic acid (LPA) is a bioactive phospholipid generated by activated platelets, astrocytes, choroidal plexus cells and microglia and is reported to play major roles in stimulating inflammatory processes. The levels of LPA in the cerebrospinal fluid (CSF) have been reported to increase acutely after non-blast related brain injuries. In the present study, we have evaluated the utility of LPA levels measured in the CSF and plasma of laboratory rats as an acute and chronic biomarker of brain injury resulting from single and tightly coupled repeated blast overpressure exposures. In the CSF, many LPA species increased at acute time-points, returned to normal levels at 1 month, and increased again at 6 months and 1 year post-blast overpressure exposures. In the plasma, several LPA species increased acutely, returned to normal levels by 24 h, and were significantly decreased at 1 year post-blast overpressure exposures. These decreases in LPA species in the plasma were associated with decreased levels of lysophosphatidyl choline, suggesting a defective upstream biosynthetic pathway of LPAs in the plasma. Notably, the changes in LPA levels in the CSF (but not plasma) negatively correlated with neurobehavioral functions in these rats, suggesting that CSF levels of LPAs may provide a suitable biomarker of bTBI that reflects severity of injury.

17.
Heliyon ; 9(5): e15616, 2023 May.
Artículo en Inglés | MEDLINE | ID: mdl-37159714

RESUMEN

Several catastrophic ammonium nitrate (AN) explosion accidents have been reported during the last decades. Previous studies have been mainly focused on investigating adverse effects caused by the AN explosion, while only a few systematically analyzed the consequences and impacts of AN explosions. This study collects data from three typical AN explosions (accidental explosion of the US fertilizer plant in 2013; an accidental explosion of China's Tianjin port in 2015, and a recent explosion (2020) of the Beirut port in Lebanon). The consequences of accidental explosions were analyzed by mathematical equations that further provide scientific explanations for AN explosions. Based on the explosives' properties on-site, these accidental explosions were caused by condensed phase explosives. Comparison with the conditions at the explosion site indicated that blast overpressure was the primary factor in the loss of life and damage to the building, while ground shock was a secondary factor. The severity of loss of life and building damage from explosions decreased with increasing distance. These distances could be calculated by the scaling law, which was replaced by the equivalent TNT mass of the explosive and the damage scale's overpressure boundary value. In addition, mapping the damaged area on a map helped in the visual presentation of the consequence assessment. The long-term environmental and ecological impact due to the explosions was also an important issue that could not be ignored. Overall, this study establishes a simple and easy-to-use method to rapidly predict and assess the consequences of an explosion, and provides technical guidance for future emergency response to similar large-scale accidents.

18.
Ann Biomed Eng ; 51(5): 1106-1118, 2023 May.
Artículo en Inglés | MEDLINE | ID: mdl-37036617

RESUMEN

Blast-induced auditory trauma is a common injury in military service members and veterans that leads to hearing loss. While the inner ear response to blast exposure is difficult to characterize experimentally, computational models have advanced to predict blast wave transmission from the ear canal to the cochlea; however, published models have either straight or spiral cochlea with fluid-filled two chambers. In this paper, we report the recently developed 3D finite element (FE) model of the human ear mimicking the anatomical structure of the 3-chambered cochlea. The model consists of the ear canal, middle ear, and two and a half turns of the cochlea with three chambers separated by the Reissner's membrane (RM) and the basilar membrane (BM). The blast overpressure measured from human temporal bone experiments was applied at the ear canal entrance and the Fluent/Mechanical coupled fluid-structure interaction analysis was conducted in ANSYS software. The FE model-derived results include the pressure in the canal near the tympanic membrane (TM) and the intracochlear pressure at scala vestibuli, the TM displacement, and the stapes footplate (SFP) displacement, which were compared with experimentally measured data in human temporal bones. The validated model was used to predict the biomechanical response of the ear to blast overpressure: distributions of the maximum strain and stress within the TM, the BM displacement variation from the base to apex, and the energy flux or total energy entering the cochlea. The comparison of intracochlear pressure and BM displacement with those from the FE model of 2-chambered cochlea indicated that the 3-chamber cochlea model with the RM and scala media chamber improved our understanding of cochlea mechanics. This most comprehensive FE model of the human ear has shown its capability to predict the middle ear and cochlea responses to blast overpressure which will advance our understanding of auditory blast injury.


Asunto(s)
Traumatismos por Explosión , Conducto Auditivo Externo , Humanos , Análisis de Elementos Finitos , Conducto Auditivo Externo/fisiología , Cóclea , Oído Medio/fisiología , Membrana Timpánica
19.
Front Neurol ; 14: 1110717, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37025202

RESUMEN

Introduction: Although previous research suggests that overpressure exposure from either high-level blast (HLB) or low-level blast (LLB) are harmful to health, to date no large-scale studies with representative samples of military personnel have utilized prospective designs and self-reported measures to examine the relationships between blast exposure and health conditions. To address these limitations, this analysis of data from the Millennium Cohort Study (MCS), the largest and longest running study of U.S. service members and veterans, examined (1) whether single or repeated HLB exposure is associated with self-reported diagnoses of illness and injury, (2) whether repeated HLB is associated with greater risk than single HLB, (3) potential adverse consequences of LLB exposure using military occupation as a proxy, and (4) the combined effects of single or repeated HLB and LLB exposure. Method: MCS participants who completed the 2011-2013 survey (N = 138,949) were classified as having been exposed to "no," "single," or "repeated" HLB exposure, and into low or high risk of exposure to LLB based on occupation. Participants self-reported diagnosis of 45 medical conditions; newly reported diagnoses were regressed on single and repeated (vs. no) HLB, occupational risk of LLB, and relevant interactions using logistic regression. Results: Single and repeated HLB were associated with new onset of 25 and 29 diagnoses, respectively; repeated HLB exposure was associated with greater risk than single HLB exposure for five diagnoses (e.g., PTSD, depression). Occupational risk of LLB was associated with 11 diagnoses (e.g., PTSD, significant hearing loss). Additionally, 14 significant interactions were detected across 11 diagnoses. Discussion: Findings suggest that overpressure exposure (including single HLB, repeated HLB, and occupational risk of LLB) may increase the risks of self-reporting clinical diagnoses of PTSD, hearing loss, chronic fatigue syndrome, neuropathy-caused reduced sensation in the hands and feet, depression, vision loss, sinusitis, reflux, and anemia. Furthermore, the combination of HLB and LLB exposure may be associated with greater risk of migraines, PTSD, and impaired fecundity. These findings provide further evidence of the potential adverse consequences associated with overpressure exposure and underscore the necessity of public health surveillance initiatives for blast exposure and/or safety recommendations for training and operational environments.

20.
Heliyon ; 9(3): e13873, 2023 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-36967925

RESUMEN

As a security protection system, the marine interdiction system can be set up outside the port to provide security protection for the ships and facilities there as well as to prevent explosions and ship collisions. This paper uses the Arbitrary Lagrangian Euler (ALE) method in ANSYS LS/DYNA to simulate a blast for an interdiction system close to the water's surface. The simulated shock wave overpressure is extracted and fitted, and when compared with the empirical formula, it is discovered that the trend and value are in good agreement. In the case of controlled calculation scale, closer to the real situation and only consider the explosion transient effect, analysis of the dynamic reaction of the interdiction system under various operating situations to test its anti-explosion performance would help to confirm the validity of the proportional burst distance as a criterion for near-water explosion damage. The safe distance for a 500 kg TNT charge is 4.62 m, and the safe distance for a 1500 kg TNT charge is 6.37 m, when the proportional burst distance reaches 0.5, some of the cable tension reaches the breaking tension level at this moment, and foam floating balls appear to fail for some elements, but the system as a whole is still in a safe state. The research will also provide support for the optimization of the interdiction system and also provide support for the optimization and development of the marine interdiction system.

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