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1.
BMJ Case Rep ; 14(10)2021 Oct 13.
Artículo en Inglés | MEDLINE | ID: mdl-34645629

RESUMEN

A 22-year-old pregnant woman was referred to our fetal medicine unit due to severe fetal growth restriction at 26 weeks of gestation. An extensive detailed ultrasound revealed signs of bilateral periventricular hyperechogenicity, suggesting fetal infection potentially due to cytomegalovirus (CMV). Doppler ultrasound showed a high peak systolic velocity in the middle cerebral artery. Percutaneous umbilical cord blood sampling confirmed fetal CMV infection and severe fetal anaemia. We present this case to highlight the importance of fetal anaemia, which can be fatal regardless of whether it is associated with generalised oedema or hydrops fetalis.


Asunto(s)
Anemia , Infecciones por Citomegalovirus , Adulto , Anemia/etiología , Infecciones por Citomegalovirus/complicaciones , Femenino , Retardo del Crecimiento Fetal/diagnóstico por imagen , Retardo del Crecimiento Fetal/etiología , Feto , Humanos , Hidropesía Fetal/diagnóstico por imagen , Hidropesía Fetal/etiología , Embarazo , Ultrasonografía Prenatal , Adulto Joven
2.
BMJ Case Rep ; 13(3)2020 Mar 25.
Artículo en Inglés | MEDLINE | ID: mdl-32213503

RESUMEN

The HIV/AIDS during pregnancy has high morbidity and mortality, without optimal prevention and treatment. The advanced stage cases are found in developing countries due to late detection, but, also in developed countries due to immigration; therefore, the professionals should know the management steps for these patients. The implementation of specific interventions can reduce vertical transmission incidence until 1%-8%. It is presented a case of a pregnant woman with AIDS detected during first hospitalisation, due to a ventilatory failure by opportunistic germs; at the delivery the specific interventions were implemented, being able to eliminate vertical transmission to the newborn. This article explains the four main aspects to be considered for reducing vertical transmission (detection of HIV, viral load levels-CD4 lymphocyte count, way and moment of childbirth and antiretroviral therapy) and shares experiences of the management of an advanced case, in order to help professionals to handle these cases and its complications.


Asunto(s)
Síndrome de Inmunodeficiencia Adquirida/transmisión , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Complicaciones Infecciosas del Embarazo/prevención & control , Síndrome de Inmunodeficiencia Adquirida/tratamiento farmacológico , Síndrome de Inmunodeficiencia Adquirida/prevención & control , Adulto , Fármacos Anti-VIH/uso terapéutico , Recuento de Linfocito CD4 , Cesárea , Resultado Fatal , Femenino , Humanos , Embarazo , Complicaciones Infecciosas del Embarazo/tratamiento farmacológico , Complicaciones Infecciosas del Embarazo/virología , Resultado del Embarazo , Carga Viral
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