RESUMEN

Five new isoprenoids, 3,4,8,16-tetra-epi-lobocrasol (1), 1,15ß-epoxy-deoxysarcophine (2), 3,4-dihydro-4α,7ß,8α-trihydroxy-Δ²-sarcophine (3), ent-sarcophyolide E (4), and 16-deacetyl- halicrasterol B (5) and ten known compounds 6‒15, were characterized from the marine soft coral Sarcophyton glaucum, collected off Taitung coastline. Their structures were defined by analyzing spectra data, especially 2D NMR and electronic circular dichroism (ECD). The structure of the known compound lobocrasol (7) was revised. Cytotoxicity potential of the isolated compounds was reported, too.

Asunto(s)

Antozoos/química , Antineoplásicos/aislamiento & purificación , Terpenos/aislamiento & purificación , Animales , Antineoplásicos/química , Antineoplásicos/farmacología , Línea Celular Tumoral , Dicroismo Circular , Humanos , Espectroscopía de Resonancia Magnética , Terpenos/química , Terpenos/farmacología