RESUMEN

Colorectal and glioblastoma cancer stem-like cells (CSCs) are essential for translational research. Cell line authentication by short tandem repeat (STR) profiling ensures reproducibility of results in oncology research. This technique enables to identify mislabeling or cross-contamination of cell lines. In our study, we provide a reference dataset for a panel of colorectal and glioblastoma CSCs that allows authentication. Each cell line was entered into the cell Line Integrated Molecular Authentication database 2.1 to be compared to the STR profiles of 4485 tumor cell lines. This article also provides clinical data of patients from whom CSCs arose and data on the parent tumor stage and mutations. STR profiles and information of our CSCs are also available in the Cellosaurus database (ExPASy) as identified by unique research resource identifier codes.

Asunto(s)

Autenticación de Línea Celular/métodos , Autenticación de Línea Celular/normas , Línea Celular Tumoral , Repeticiones de Microsatélite , Células Madre Neoplásicas , Adulto , Anciano , Anciano de 80 o más Años , Neoplasias Colorrectales/genética , Conjuntos de Datos como Asunto , Femenino , Perfilación de la Expresión Génica/métodos , Perfilación de la Expresión Génica/normas , Glioblastoma/genética , Humanos , Masculino , Persona de Mediana Edad