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PURPOSE: This trial evaluated clinical outcomes of fixed and removable implant-supported prostheses for rehabilitation of atrophied distal extension maxillary ridges. MATERIALS AND METHODS: A total of 54 participants with atrophied distal extension maxillary ridges were randomly assigned into three groups (n = 18/group). Group I (SLF); participants treated with fixed restoration supported by three long implants after sinus augmentation, Group II (SF); participants treated with fixed restoration supported by one long and two short implants, and Group III (OD): participants treated with removable partial denture assisted by one long implant that was placed mesial to maxillary sinus (IARPD). Modified plaque index (MPI), modified gingival index (MGI), pocket depth (PD), implant stability (IS), and crestal bone loss (CBL) were measured after prosthesis insertion (T0), 6 (T6), and 12 months (T12) after insertion. Patient satisfaction was measured at T12 using a visual analog scale (VAS). RESULTS: The implant survival rates were 96.8%, 92.4%, and 84.6% for SLF, SF, and OD groups respectively. The SLF recorded the highest MPI, MGI, PD, and IS values, followed by the SF, and the OD showed the lowest values. The OD recorded the highest CBL followed by the SF and the SLF showed the lowest CBL. With exception of satisfaction with surgery and cleaning, SLF and SF groups recorded significantly higher patient satisfaction than the OD for all VAS questions. CONCLUSION: Fixed restorations supported with either long or short implants were associated with improved implant stability, reduced bone loss, and increased patient satisfaction compared to implant-assisted RPDs. However, implant-assisted RPDs were associated with more favorable peri-implant soft tissue health and increased satisfaction with surgery, healing, and cleaning.

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Over the past decade, emerging evidence indicates a strong relationship between prosthetic design and peri-implant tissue health. The objective of this narrative review was to evaluate the evidence for the corresponding implant prosthodontic design factors on the risk to peri-implant tissue health. One of the most important factors to achieve an acceptable implant restorative design is the ideal implant position. Malpositioned implants often result in a restorative emergence profile at the implant-abutment junction that can restrict the access for patients to perform adequate oral hygiene. Inadequate cleansability and poor oral hygiene has been reported as a precipitating factors to induce the peri-implant mucositis and peri-implantitis and are influenced by restorative contours. The implant-abutment connection, restorative material selection and restoration design are also reported in the literature as having the potential to influence peri-implant sort tissue health.

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BACKGROUND: Strong evidence suggests the infectious nature of peri-implant diseases occurring in susceptible hosts. Epidemiological reports, though, indicate that peri-implantitis is a site-specific entity. Hence, the significance of local factors that may predispose/precipitate plaque accumulation and the impact of systemic drivers that alter the immune response are relevant in the prevention and management of peri-implant disorders. PURPOSE: The purpose of the present review is to shed light on the significance of local and systemic factors on peri-implant diseases, making special emphasis on the associations with peri-implantitis. METHODS: The biologic plausibility and supporting evidence aiming at providing a concluding remark were explored in the recent scientific literature for local predisposing/precipitating factors and systemic drivers related to peri-implant diseases. RESULTS: Local predisposing factors such as soft tissue characteristics, implant position and prosthetic design proved being strongly associated with the occurrence of peri-implant diseases. Hard tissue characteristics, however, failed to demonstrate having a direct association with peri-implant diseases. Robust data points toward the strong link between residual sub-mucosal cement and peri-implant diseases, while limited data suggests the impact of residual sub-mucosal floss and peri-implantitis. Systemic drivers/habits such as hyperglycemia and smoking showed a strong negative impact on peri-implantitis. However, there is insufficient evidence to claim for any link between metabolic syndrome, atherosclerotic cardiovascular disease, and obesity and peri-implant diseases. CONCLUSION: Local predisposing/precipitating factors and systemic drivers may increase the risk of peri-implant diseases. Therefore, comprehensive anamnesis of the patients, educational/motivational programs and exhaustive prosthetically-driven treatment planning must be fostered aiming at reducing the rate of biological complications in implant dentistry.

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AIM: The study aimed to evaluate the effect of implant-supported prosthesis in completely edentulous participants in terms of osseoperception ability, neural activity, and stereognostic ability in comparison to removable prosthetic options. MATERIALS AND METHODS: A total sample of 18 patients, irrespective of gender and age were allocated into three groups according to the three-treatment protocol (upper and lower complete denture, upper complete denture opposing lower implant-retained overdenture, implant-supported fixed prosthesis in both arches). Four weeks after completion of the treatment procedure active tactile sensibility (ATS) was checked by using varying thicknesses (12, 40, 80, 100, 200 µ) of articulating foils and papers. Functional magnetic resonance imaging (fMRI) was performed to record neurophysiological activity in cerebral cortex in all the participants. Various forms of test pieces (heat cure acrylic resin) were used to evaluate stereognostic ability. Data regarding the neurophysiological activity were analyzed by using Krushkal-Wallis test and p ≤ 0.05 was considered to be statistically significant. Data from stereognostic ability test procedure and ATS were compared by using chi-squared test and p ≤ 0.05 was considered to be statistically significant. RESULTS: Statistically significant difference was found in between the articulating foils in terms of true negative responses as the foil thickness increased in participants wearing complete denture in both the arches (p = 0.004) and implant-supported fixed prosthesis in both the arches (p = 0.010). Participants in implant-supported fixed prosthesis group showed significantly more activation in primary motor cortex (right side), somatosensory cortex (left side), angular gyrus (both sides), temporal lobe (left) compared to other groups. No significant difference found in thalamus and premotor cortex region in between the participants of different groups. No statistically significant difference found in between the groups in terms of true responses identifying correct shapes. Mean number of correct responses in stereognostic ability test were 4.16 (83.33%), 3.5 (70%), 3.83 (76.66%) for participants of complete denture group, upper complete denture opposing lower implant retained overdenture group, and implant-supported fixed prosthesis group, respectively. CONCLUSION: Primary motor cortex, somatosensory cortex, and other regions of brain were diffusely activated in participants wearing implant-supported fixed prosthesis in both the arches. Less number of false responses were recorded in participants of implant-supported fixed prosthesis group and upper complete denture opposing lower implant-retained overdenture group in ATS test compared to participants wearing complete denture in both the arches.

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For most of the last century, conventional complete dentures have been the standard of care and the most common treatment for edentulous patients. Technological advancements in fabrication techniques may significantly reduce the number of office visits required to fabricate complete dentures. Immediate occlusal loading with mandibular full arch prostheses has been extensively researched and is now one of the standards of care for edentulous patients. A clinical technique for converting a mandibular immediate complete denture to an interim full arch, screw-retained fixed prosthesis with novel implant restorative components for immediate loading on four implants is described.

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BACKGROUND: Dental implant is widely used as a treatment for missing teeth. However, proximal contact loss (PCL) between implant-supported fixed dental prostheses (FDP) and adjacent teeth has been reported as one of the common and adverse complications. PURPOSE: We aimed to evaluate the prevalence of PCL up to 18 years after implant prosthesis delivery and to analyze associated factors. MATERIALS AND METHODS: A total of 317 patients who had received implant FDP at the posterior regions were included in this study. Nineteen factors were assessed, including degrees of proximal contact tightness, oral hygiene, periodontal conditions, and food impaction. Chi-square test, univariate generalized estimating equation (GEE), and multivariate GEE were utilized to identify factors influencing PCL. RESULTS: Proximal contacts at both the mesial and distal (if present) sides were evaluated. The mesial contact loss rate (27%) was significantly higher than that of the distal contact loss (5%). Increased PCL rates over functional time were observed at both the mesial and distal sides. Six factors, including patient age, implant functional years, frequent use of interdental brushes, splinting or single implant, plunger cusp, and food impaction, were revealed to be associated with the mesial PCL using the chi-square test and univariate GEE analysis. However, only functional years (>5 years), frequent use of interdental brushes and food impaction showed significance in the multivariate GEE. CONCLUSIONS: Mesial PCL was frequent and increased over functional years. An occlusal retainer and routine follow-up may help prevent PCL. Although oral hygiene conditions contribute little to PCL, food impaction and frequent use of interdental brushes were influential factors.

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PURPOSE: The behavior of implant-crowns fabricated from recently introduced CAD-CAM zirconia-reinforced lithium silicate ceramic (ZLS) or a hybrid ceramic containing resin-reinforced glass network (HC) for strains around the implant platform is not well-known. A force absorption capacity of the latter has been claimed by the manufacturer. The aim of this study was to measure and compare recently introduced ZLS and HC with commonly used CAD-CAM implant crown materials for strain distribution around the implant platform. METHODS: Four implants (Legacy 1; Implant Direct) were placed into a resin block. Zirconia abutments (Straight contoured stock abutment; Implant Direct) were torqued into the implant fixtures to support crowns that were milled from a virtual design using four different CAD-CAM materials (Vita Suprinity PC (ZLS), Vita Enamix (HC), IPS Emax, ZirCAD Zirkonzahn) (N = 20). The crowns were cemented with a resin cement, loaded and strain values were recorded. Three-dimensional digital image correlation (3D-DIC) was used to measure compressive and tensile strains around the implant platforms. The tensile and compressive strains were recorded for each test and first analyzed for equality of variance using Levene's test, and further tested using a 2-way ANOVA repeated measures analysis of variance (α = .05). RESULTS: The data analysis showed no statistically significant effect of crown material on the generated strains (P > .05). Compressive strains were significantly higher than the tensile strains (P < .05). One of the HC crowns fractured during loading. CONCLUSIONS: Strains generated around implant platform when new generation CAD-CAM crown materials were used was similar to strains observed when CAD-CAM zirconia and lithium disilicate crowns were used. New generation crown materials did not have a significant load absorption effect to change or minimize the strains generated around the implant platform.

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Complete arch fixed implant supported prosthesis made of monolithic zirconia is a popular treatment option with minimal complications, as documented in the literature over a 5-year period. One of the limitations of this material is its inability to be used when the span between adjacent implants is excessively long. A potential solution to mitigate this problem is to support the zirconia prosthesis with a metal substructure, which intrinsically has higher tensile strength. This clinical report describes the successful use of this prosthetic design in a male patient with bruxism and history of multiple implant failures in the maxilla. This resulted in a large anterior-posterior span between the anterior implants in the maxillary lateral incisor region and the distal implants in the pterygoid region. This article also describes the use of a split file digital workflow to scan the prototype prosthesis and then digitally design and mill the screw-retained cobalt chromium bar, as well as the overlaying of zirconia prosthesis which was retained by separate screws. This novel approach offers promise for management of the atrophic maxilla where implants with remote anchorage are used resulting in broader distribution of implants.

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BACKGROUND: The effect of the type of implant superstructure on oral health-related quality of life (OHRQoL) among edentulous patients remains controversial. PURPOSE: The purpose of this study is to investigate the association between the type of implant superstructure and OHRQoL. MATERIALS AND METHODS: Seventy-two completely edentulous patients who received implant fixed complete dentures (IFCDs) or implant overdentures (IODs) were administered the Oral Health Impact Profile (OHIP) questionnaire during the post-treatment maintenance period. The OHIP summary score, as well as the four dimension scores, were calculated to evaluate OHRQoL. RESULTS: The mean OHIP summary score for the IFCD group tended to be lower than that for the IOD group, but this difference was not statistically significant (19.9 ± 21.9, 22.8 ± 18.2, respectively; P = .57). However, a significant group difference was found in the four dimension scores (P < .01), with the OHIP item scores representing masticatory function being significantly lower in the IFCD group than in the IOD group (P < .05). CONCLUSIONS: Our results suggested that patients with an IOD exhibited comparable OHRQoL to those with an IFCD, with the exception of perceived masticatory function.

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Acromegaly is an adult endocrine disorder that results from excessive growth hormone after closure of the growth plates and is associated with significant morbidity and increased mortality. The orofacial features of patients with acromegaly are thick lips with a tendency towards mandibular overgrowth with prognathism, jaw thickening, maxillary widening, drifting of teeth, malocclusion, and increased gonial angle, all of which can challenge the prosthodontist in dental rehabilitation. Additionally, excessive secretion of growth hormone and insulin-like growth factors have been shown to increase bone turnover, which in turn leads to weakening of bone microarchitecture and high risk of fragility fractures. This clinical report describes the 4-year follow-up of a 59-year-old white male with acromegaly, who was managed successfully by using dental implants for replacing his missing teeth. Considerations related to treatment planning, implant surgery, bone remodeling, and management of dental occlusion are discussed. This is the first clinical report in the dental literature describing the use of dental implants in an acromegaly patient.

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Mandibular complete-arch fixed implant-supported prostheses are recognized as one of the earliest and most popular prostheses in implant dentistry. This prosthesis was the main focus in the early era of osseointegration. Despite its widespread popularity, few clinical reports have described long-term follow-up greater than 10 years for this type of prosthesis. This report describes a 30-year follow-up of a patient who underwent treatment for a mandibular complete-arch fixed implant-supported prosthesis with 4 machined surfaced implants, opposing a maxillary complete denture. This report documents a variety of photographs and radiographs taken over a period of 30 years to compare bone levels at various stages of care and maintenance, including de novo bone formation underneath the distal cantilevers due to functional loading. The biologic and biomechanical response to this treatment protocol and long-term clinical observations and prosthodontic outcome and maintenance needs are also addressed.

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Oral lichen planus is associated with the Koebner phenomenon, and trauma may exacerbate oral lesions. Short dental implants, as alternatives to bony augmentation, would reduce the number of interventions and their morbidity. However, we know of no studies that have analysed the long-term outcomes of short implants in patients with oral lichen planus. We have therefore designed a retrospective study of such patients treated with short implants (≤8.5mm long), with survival of implants as the main outcome. The secondary outcomes were marginal bone loss and the development of complications. We calculated the implants' survival and compared the outcomes statistically between erosive and reticular oral lichen planus. Sixty-six short implants were placed in 23 patients with a mean (SD) age of 58 (7) years. The mean (SD) peri-implant bone loss was 0.96 (0.89) mm mesially and 0.99 (1.1) mm distally. Sixty-five of the 66 implants survived with a mean (SD) follow-up of 68 (32) months, and there were no significant differences between erosive and reticular disease. Stable long-term outcomes can be expected for short implants placed in patients with oral lichen planus, and graftless rehabilitation of missing teeth could be possible in these patients if short implants were used.

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BACKGROUND: The biomechanical behavior of implant-supported titanium and zirconia full-arch fixed dental prosthesis (FAFDP) frameworks require further investigation. PURPOSE: Strains transferred by implant-supported titanium (Ti) and zirconia (Zr) FAFDP frameworks were analyzed. MATERIALS AND METHODS: Maxillary 14-unit FAFDPs supported by 6 implants and 12-unit FAFDPs supported by 4 implants were tested. One-piece frameworks were fabricated by computer-aided design/computer-aided manufacturing. Four groups were divided (n = 3): G1, Ti-6 implants; G2, Zr-6 implants; G3, Ti-4 implants; G4, Zr-4 implants. A 250 N single-point load was applied on the second premolar. A three-dimensional digital image correlation system recorded framework and maxilla model surface deformation. RESULTS: The following strains (µS) averaged over the length of the second premolar were calculated: frameworks, G1 (321.82 ± 111.29), G2 (638.87 ± 108.64), G3 (377.77 ± 28.64), G4 (434.18 ± 132.21); model surface, G1 (473.99 ± 48.69), G2 (653.93 ± 45.26), G3 (1082.50 ± 71.14), G4 (1218.26 ± 230.37). Zirconia frameworks supported by 6 implants (G2) presented higher surface strains (P < .05). FAFDPs with titanium frameworks transferred significantly lower strains to the supporting maxilla when 6 implants were used (G1) (P < .05). Both framework materials transferred similar strains when supported by 4 implants (G3 and G4) (P > .05). CONCLUSIONS: Zirconia frameworks supported by 6 implants showed higher strains. FAFDPs supported by 6 implants transferred less strains to the supporting maxilla, irrespective of framework material.

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Successful rehabilitation of a patient should restore function, esthetic, and speech by prosthesis. Treatment modalities vary from patient to patient. Semi-precision attachments and implants offer several advantages over the traditional approach. The aim and objective of this report was to assess a case of a 55-year-old female patient who had lost all her teeth, except maxillary canines #13 and #23 and with severe bone loss in the mandible. Tooth-supported bar attachment was planned for maxilla, and a total of five dental implants were placed in the mandible using a flapless approach aided by radiographic gutta-percha surgical stents over panoramic two-dimensional imaging. Customized, radiographic stents help for the placement of implant in the view of paralleling and flapless surgery, completely. An immediate loading protocol is adopted as from day of the surgery to 6 weeks along with implant supported full arch fixed dentures after 4 months. The outcome of the treatment was impressive, and the patient gave a positive response with superb esthetics and functions.

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BACKGROUND: Implant esthetics may benefit from individualized zirconia abutments copying the emergence profile of the natural tooth and delivered within days after immediate implant insertion. PURPOSE: To investigate the esthetic outcome of the Copy-Abutment technique using the Pink Esthetic Score (PES). MATERIALS AND METHODS: A total of 77 patients with single-tooth implants in the anterior maxilla restored at the day of immediate implant placement using Copy-Abutments and provisional crowns were followed-up after 1 week, 1 month, 4 months, 6 months, 1, 2, 3, 4, and 5 years to assess implant esthetics. RESULTS: PES ranged between 7 and 14 (median: 13) and improved significantly between the 6 month and 1 year follow-up (p < .001), then remained stable up to the fifth year. Significant improvement was seen for the variables PES-6 soft tissue color (p = .002) and PES-7 soft tissue texture (p < .001) up to the 1 year follow-up, while PES-5 alveolar process deficiency deteriorated (p = .016). Mean mucosal recession was 0.26 ± 0.86 mm (range: 0-1.6) after 5 years and not related to gingival biotype. CONCLUSION: Copy-Abutments for immediate restoration of implants in the esthetic zone show satisfactory long-term esthetic outcomes.

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BACKGROUND: During archaeological excavation, carried out in the S. Francesco Monastery at Lucca (Tuscany, Italy), a golden dental appliance was discovered. The prosthesis was found, together with commingled human remains, in the collective tomb of the aristocratic family of the Guinigi, a powerful family who governed Lucca from 1392 until 1429. The exact archaeological dating of the prosthesis was not possible, but some elements suggest a dating to the beginning of the 17th century. PURPOSE: Aim of the paper is to study and describe the dental appliance trough a multidisciplinary approach. MATERIALS AND METHODS: Macroscopical and micro-CT examinations were performed to investigate the technics used for the realization of the dental prosthesis. SEM analysis was performed to study alloy composition of the metallic fixing lamina and microstructure of the deposits on the dental surface. RESULTS: The dental prosthesis consists in five mandibular teeth: three central incisors and two lateral canines linked together by a golden band inserted into the dental roots to replace the anterior arch of the jaw. Micro-CT scan revealed the presence of two small golden pins inserted into each tooth crossing the root and fixing the teeth to the internal gold band. SEM examination of the lamina indicated a homogeneous composition, with average contents of 73 wt% gold, 15.6 wt% Ag, and 11.4 wt% Cu. Apposition of dental calculus on the teeth indicated that the prosthesis had been worn for a long period. CONCLUSIONS: This dental prosthesis provides a unique finding of technologically advanced dentistry in this period. In fact, during the Early Modern Age, some authors described gold band technology for the replacement of missing teeth; nevertheless, no direct evidences of these devices have been brought to light up so far.

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Objective@#To evaluate the plaque distribution on the fitting surface of fixed implant prostheses which were supported by multi-unit abutment. @*Methods @# 21 patients with maxillary full-arch implant-supported fixed prostheses were collected. Plaque accumulation at the fitting surfaces were evaluated 3 months after restoration, by analyzing the digital photographs recorded by Imag e J 2.1.4.7.@*Results@#The average percentage of area covered with plaque was (46.13 ± 7.23)%. Plaque accumulation on the buccal and palatal area were (41.53 ± 3.08) and (53.76 ± 3.07)% respec⁃ tively, with a significant difference (t = 16.750, P < 0.001). The free area (71.86 ± 2.00) % was significantly higher than the anterior area (48.85 ± 2.09)% (t = 40.445, P < 0.001), andalso the middle area (49.33 ± 0.98)% (t = 47.124 , P < 0.001). The plaque percentage was higher when the distance between the implants was shorter.@*Conclusion@#To Minimize the palatal extension and free area of the prostheses, and to maximize the distances between the implants, were helpful to improve the oral hygiene control. It might be the key to keep a good outcome of the maxillary full-arch implant-supported fixed prostheses.

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More studies evaluating the outcome of dental implant restorations in diabetics are needed. To investigate the outcome of immediate function implant rehabilitations in diabetic patients. This retrospective cohort study included 70 diabetic patients (type 1 = six patients; type 2 = 64 patients; 33 females and 37 males, mean age=59 years), rehabilitated with 352 implants. Primary outcome measure was implant survival estimated at 5 years through the Kaplan-Meier product limit estimator using the patient as unit of analysis (first implant failure as reference); secondary outcome measures were marginal bone loss and biological complications. Risk indicators associated with bone loss >2·0 mm were tested in a multivariate logistic regression model. The level of significance considered was 5%. Seven patients were lost to follow-up (10%). Seven patients lost ten implants rendering a global implant cumulative survival rate for diabetic patients of 89·8% (type 1 = 80·0%; type 2 = 90·5%). The average (95% confidence interval) marginal bone loss at 1 and 5 years was 1·64 mm (0·00;3·32) and 2·55 mm (1·38;3·72) for type 1 diabetic patients, 0·79 mm (0·59;1·00) and 1·45 mm (1·09;1·82) for type 2 diabetic patients and 0·88 mm (0·65;1·10) and 1·56 mm (1·21;1·91) overall. Biological complications occurred in seven patients. Female gender (OR = 28·1) and smoking habits (OR = 10·3) were risk indicators for marginal bone loss >2·0 mm at 5 years when controlled for other variables of interest. Implant rehabilitations represent a valid treatment for diabetic patients, with a good risk/benefit ratio. Female gender and smoking habits were risk indicators for a higher marginal bone resorption at 5 years.

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BACKGROUND: Achieving an optimal esthetic result using dental implants is challenging. Fixed implant-supported provisional crowns are often used to customize the emergence profile and to individualize the surrounding peri-implant soft tissue. PURPOSE: The objective of this study is to evaluate whether the use of a provisional implant-supported crown leads to an esthetic benefit on implants that are placed in the esthetic zone. The null hypothesis is that there is no-difference between the two study groups. MATERIAL AND METHODS: Twenty single implants (Bone Level, Straumann AG, Basel, Switzerland) were inserted in consecutive patients. After reopening, a randomization process assigned them to either cohort group 1: a provisional phase with soft tissue conditioning using the "dynamic compression technique" or cohort group 2: without a provisional. Implants were finally restored with an all-ceramic crown. Follow-up examinations were performed at 3 and 12 months including implant success and survival, clinical, and radiographic parameters. RESULTS: After 1 year all implants successfully integrated, mean values of combined modPES and WES were 16.7 for group 1 and 10.5 for Group 2. This was statistically significant. Mean bone loss after 1 year was -0.09 and -0.08 for groups 1 and 2, respectively, without being statistically significant. CONCLUSION: A provisional phase with soft tissue conditioning does improve the final esthetic result.

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BACKGROUND: Long-term data on clinical outcomes of restorations attached to implants via zinc oxide (ZnO) cement have been sparse. PURPOSE: The purpose of this study was to retrospectively investigate decementation rates and peri-implant tissue status of implant-supported fixed restorations retained by ZnO cement. MATERIALS AND METHODS: Between 1989 and 2003, 63 partially edentulous patients received 93 implants. Of these, 27 patients received 36 screwed single crowns (SC) and served as a control (C group). The other 36 patients had their restorations cemented using ZnO cement. They were subdivided into a SC group and a fixed dental prosthesis (FDP) group. After between 10 and 23 years (mean: 13.22 ± 3.21), all decementation events and peri-implant soft tissue status were evaluated using patient records. RESULTS: Decementation was assessed in 57 implants supporting 30 SCs and 16 FDPs. Five cases of decementation (8.77%) were recorded after a mean of 9.27 ± 7.05 years (range: 4.81-21.79). In the control group of vertically screwed SCs, five events of screw loosening (13.89%) were recorded in five patients (18.52%) after a mean of 5.84 ± 5.96 years (range: 0.56-15.05) within a 14.30 year observation period. No cases of peri-implantitis were observed in any group. The mean values of periodontal probing depths and bleeding on probing (BOP+) were 3.74 mm and 31.58%, respectively, for ZnO-cemented restorations, versus 3.76 mm and 25%, respectively, for the C group. No significant correlations regarding technical/biologic complications between the groups were detected. CONCLUSIONS: Within the limitations of this study, we conclude that the use of ZnO cement provides sufficient retention of implant-supported fixed restorations over long periods without biologic complications in form of peri-implantitis.

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