RESUMEN
This paper aims to understand the origins of what is seen as a lack of understanding about the seriousness of our current times. The author's view is that this failure is due to a lack of awareness that our human species is destructive, arrogant, self-centred and ignorant of the laws of nature and the wonderful complexity of the environment that it destroys. Possible new values that could support a new civilizational framework are presented.
Cet article vise à comprendre les origines de ce qui est perçu comme un manque de compréhension de la gravité de notre époque actuelle. L'auteur suggère que cet échec provient d'un déficit de conscience en ce qui concerne le fait que notre espèce humaine est destructrice, arrogante, centrée sur elle-même et ignorante des lois de la nature et de la merveilleuse complexité de l'environnement qu'elle détruit. De nouvelles valeurs envisageables - qui pourraient soutenir une nouvelle structure pour la civilisation - sont présentées.
El presente trabajo intenta comprender los orígenes de aquello que es visto como una falta de comprensión sobre la seriedad de nuestros tiempos actuales. La perspectiva del autor es que esta falla se debe a una falta de conciencia sobre la destructividad, arrogancia, auto-centración e ignorancia de nuestra especie humana acerca de las leyes de la naturaleza y la maravillosa complejidad del medio ambiente al que destruye. Se presentan nuevos valores posibles que puedan apoyar un nuevo marco de referencia para nuestra civilización.
Este artigo tem como objetivo entender as origens do que é visto como uma falta de compreensão sobre a seriedade de nossos tempos atuais. A visão do autor é que esse fracasso se deve à falta de consciência de que nossa espécie humana é destrutiva, arrogante, egocêntrica e ignorante das leis da natureza e da maravilhosa complexidade do ambiente que ela destrói. Possíveis novos valores que possam apoiar um novo quadro civilizacional são apresentados.
Asunto(s)
Trastornos Mentales , HumanosRESUMEN
In this review, we present the environmental perspectives of the viruses and antiviral drugs related to SARS-CoV-2. The present review paper discusses occurrence, fate, transport, susceptibility, and inactivation mechanisms of viruses in the environment as well as environmental occurrence and fate of antiviral drugs, and prospects (prevalence and occurrence) of antiviral drug resistance (both antiviral drug resistant viruses and antiviral resistance in the human). During winter, the number of viral disease cases and environmental occurrence of antiviral drug surge due to various biotic and abiotic factors such as transmission pathways, human behaviour, susceptibility, and immunity as well as cold climatic conditions. Adsorption and persistence critically determine the fate and transport of viruses in the environment. Inactivation and disinfection of virus include UV, alcohol, and other chemical-base methods but the susceptibility of virus against these methods varies. Wastewater treatment plants (WWTPs) are major reserviors of antiviral drugs and their metabolites and transformation products. Ecotoxicity of antiviral drug residues against aquatic organisms have been reported, however more threatening is the development of antiviral resistance, both in humans and in wild animal reservoirs. In particular, emergence of antiviral drug-resistant viruses via exposure of wild animals to high loads of antiviral residues during the current pandemic needs further evaluation.
Asunto(s)
Antivirales , Farmacorresistencia Viral/efectos de los fármacos , Microbiología Ambiental , Contaminantes Ambientales , SARS-CoV-2 , Inactivación de Virus , Adsorción , Animales , Antivirales/química , Antivirales/uso terapéutico , Antivirales/toxicidad , Organismos Acuáticos/efectos de los fármacos , COVID-19/epidemiología , COVID-19/etiología , Ecotoxicología , Contaminantes Ambientales/química , Contaminantes Ambientales/uso terapéutico , Contaminantes Ambientales/toxicidad , Humanos , SARS-CoV-2/efectos de los fármacos , SARS-CoV-2/patogenicidad , Estaciones del Año , Inactivación de Virus/efectos de los fármacos , Inactivación de Virus/efectos de la radiación , Purificación del Agua , Tratamiento Farmacológico de COVID-19RESUMEN
When providing sleep medical services special aspects must be taken into account in the context of the coronavirus pandemic. Despite all prevention, due to the high number of unrecognized cases, SARS-CoV2 contacts in the sleep laboratory must be expected and appropriate precautions are necessary. Nevertheless, the continuation or resumption of sleep medical services under the appropriate hygiene measures is strongly recommended to avoid medical and psychosocial complications. There is no evidence for a deterioration of COVID-19 through CPAP therapy. In principle, the application of positive pressure therapy via various mask systems can be accompanied by the formation of infectious aerosols. In the case of confirmed infection with SARS-CoV2, a pre-existing PAP therapy should be continued in an outpatient setting in accordance with the local guidelines for home isolation, since discontinuation of PAP therapy is associated with additional cardiopulmonary complications due to the untreated sleep-related breathing disorder. According to the current state of knowledge inhalation therapy, nasal high-flow (NHF), and PAP therapy can be carried out without increased risk of infection for health care workers (HCW) as long as appropriate personal protective equipment (eye protection, FFP2 or FFP-3 mask, gown) is being used.This position paper of the German Society for Pneumology and Respiratory Medicine (DGP) and the German Society for Sleep Medicine (DGSM) offers detailed recommendations for the implementation of sleep medicine diagnostics and therapy in the context of the coronavirus pandemic.
RESUMEN
Objective:To analyze the clinical efficacy of traditional Chinese medicine（TCM） Toujie Quwen granules in the treatment of coronavirs disease-2019（COVID-19） in the early stage, and its effect on relevant inflammatory index expression of COVID-19. Method:A total of 65 COVID-19 cases were diagnosed and divided into 2 groups: the treatment group （n=32） and the control group （n=33）. Before and after treatment，TCM syndrome score，WBC，LYM，LYM%，NEU%，PCT，CRP and D-dimer were compared. Result:After 10 days of treatment，the TCM syndrome score of the treatment group was significantly reduced（P<0.05），while the absolute value of lymphocyte was up-regulated，with statistically significant differences（P<0.05）， according to the inter-group comparison, there were statistically significant differences in the absolute value of LYM and NEU%（P<0.05）. There was no significant difference in WBC count and LYM%. The levels of CRP，PCT and D-dimer in the two groups were reduced after treatment，with statistically significant differences between two groups （P<0.05）. After treatment，the differences of CRP and PCT was statistically significant between both groups（P<0.05），but the difference in D-dimer was not statistically significant. There was no difference in the effect of chest CT examination between the both groups. Conclusion:The clinical syndrome and inflammatory particles of COVID-19 can be alleviated by early and timely use of Toujie Quwen granules.