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A escolha da plataforma protética em implantodontia é fundamental para garantir o sucesso a longo prazo dos procedimentos. Todos os tipos de conexão protética apresentam vantagens e desvantagens, cabendo ao cirurgião-dentista optar pelo o que melhor se adepta ao seu caso. Uma revisão de literatura foi realizada, abrangendo estudos relevantes que compararam essas duas plataformas protéticas em termos de biomecânica e estética. Foram analisadas revisões de literatura e estudos in vitro, sob as palavras-chave "cone morse", "biomechanics", "abuptment". As pesquisas foram feitas nas bases de dados Scielo e PubMed, e os artigos escolhidos deveriam abordar a estabilidade das conexões, a preservação óssea e a estética peri-implantar. Os resultados da revisão demonstram que a plataforma Cone Morse oferece uma interface mais estável, reduz o afrouxamento de parafusos e minimiza a infiltração bacteriana. Com isso, o Cone Morse contribui para a preservação das estruturas ósseas e gengivais ao redor do implante, tornando-se uma escolha valiosa, especialmente em procedimentos de reabilitação estética.

A choice of the prosthetic platform in implant dentistry is fundamental to ensure long-term success of procedures. All types of prosthetic connections have their advantages and disadvantages, and it's up to the dentist to choose what best suits their case. A literature review was conducted, encompassing relevant studies comparing these two prosthetic platforms in terms of biomechanics and aesthetics. Literature reviews and in vitro studies were analyzed using keywords such as "Cone Morse," "biomechanics," and "abutment." The research was conducted on Scielo and PubMed databases, and the selected articles should address connection stability, bone preservation, and peri-implant aesthetics. The review results demonstrate that the Cone Morse platform offers a more stable interface, reduces screw loosening, and minimizes bacterial infiltration. As a result, Cone Morse contributes to the preservation of bone and gingival structures around the implant, making it a valuable choice, especially in aesthetic rehabilitation procedures.

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OBJECTIVES: To reveal the force profiles recorded by haptic autonomous robotic force feedback during the transcrestal sinus floor elevation (TSFE) process, providing a reference for the surgery strategy during TSFE. MATERIALS AND METHODS: A total of 42 maxillary sinus models with different angles of the sinus floor (30°, 40°, 50°, 60°, 70°, 80°, and 90°, compared to vertical plane) were 3D printed. Implant site preparation was performed using a robotic system, and the total force (Ft) and axial force along the drill (Fz) during the surgery were recorded by the haptic robotic arm. The actual initial breakthrough point (drill contacting sinus floor) and complete breakthrough point (drill penetrating the sinus floor) were defined visually (the actual IBP and the actual CBP). The theoretical initial breakthrough point (the theoretical IBP) and the theoretical complete breakthrough point (the theoretical CBP) defined by the robot-guided system and the CBCT were determined by real-time force feedback and imaging distance measurement, respectively. The distance from the bottom of the resin model to the actual IBP and the actual CBP was defined as Di and Dt, respectively. RESULTS: The difference in Fz began to increase significantly at 70°, while the difference in Ft became significant at 60°. When the angle was greater than 70°, there was no significant difference in the discrepancy between the actual and theoretical perforation points. Compared to judging the breakthrough point by CBCT, real-time force feedback TSFE under robotic surgery achieved more accurate initial breakthrough point detection. CONCLUSIONS: The smaller the angle, the larger the breakthrough force for the drill. The real-time force feedback of haptic robotic system during TSFE could provide reliable reference for dentists. More clinical studies are needed to further validate the application of robotic surgery assisted TSFE.

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Introduction Impairment of the inferior alveolar/dental nerve (IAN) is a relatively uncommon complication after lower wisdom tooth removal. Studies report varying incidences of IAN injury, with dysesthesia being noted as particularly distressing and 0-0.9% cases extending for a long duration. Neurosensory disruptions can severely impact speech, chewing, swallowing, and social interactions, leading to chronic pain and a lower quality of life. It also poses a risk of inadvertent injuries during meals. Although orthopantomogram (OPG) is primarily used for diagnosis, but when the lower wisdom tooth and nerve are in close approximation, cone beam computed tomography (CBCT) is recommended, despite its higher cost and radiation exposure. A white paper on third molar management necessitates further research on CBCT's role, citing conflicting evidence. Further in a multicentric trial, the difference between the OPG versus CBCT group was not statistically significant due to the low incidence of IAN injuries. They have emphasized the need for more well-designed studies to reach a statistically significant conclusion by meta-analyses. Hence, this study aims to provide additional evidence. Methods It is a two-arm, parallel, diagnostic study design involving individuals between the ages of 18 and 50 years, requiring lower wisdom tooth removal that is closely approximated with the nerve. Eligible adults, based on the specified inclusion/exclusion criteria, will be recruited into the study; informed consent will be obtained; then assigned randomly to the OPG or CBCT group using a random computer-generated sequence. Extractions will be done under local anesthesia using a standard surgical protocol with odontectomy. Surgical variables will include the experience of the surgeon, amongst others. The outcome variables will be recorded using patient interviews (subjective) and objective examinations from day one up to six months after surgery. The primary outcome will comprise the number of patients reporting abnormal sensations post-surgery. Secondary outcomes will include objectively confirmed IAN injuries and permanent IAN injuries (>6 months). Results will be analyzed statistically to look for significance and possible risk factors associated with it. Results If a statistically significant result is obtained, then we can deliberately reduce CBCT referrals and reserve them only for high-risk cases, wherein the risk of IAN injury cannot be predicted by OPG alone. If the experience of the surgeon proves to be an important risk factor, then it can also help refer high-risk patients to surgeons with more experience. Conclusion If CBCT proves to be statistically superior to OPG in the prediction of nerve injury, then we will be able to avoid significant morbidity and improve the quality of life of such patients by either modifying the surgical steps or by choosing other conservative treatment modalities. Further, this may reduce unnecessary CBCT referrals, thus reducing radiation exposure, the cost to patients, and, in turn, national healthcare expenditure. Besides, CBCT is not available at all centers, so a lot of low-risk patients can be managed safely at primary health centers, thus reducing the urban patient load.

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Background: Cone beam computed tomography (CBCT) and megavoltage computed tomography (MVCT)-based images demonstrate measurable radiomics features that are potentially prognostic. This study aims to systematically synthesize the current research applying radiomics in head and neck cancers for outcome prediction and to assess the radiomics quality score (RQS) of the studies. Methods: A systematic search was performed to identify available studies on PubMed, Web of Science, and Scopus databases. Studies related to radiomics in oncology/radiotherapy fields and based on predefined Patient, Intervention, Comparator, Outcome, and Study design (PICOS) criteria were included. The methodological quality of the included study was evaluated independently by two reviewers according to the RQS. The Mann-Whitney U test was performed according to subgroups. The P values <0.05 were considered statistically significant. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 reporting guidelines were adhered to. Results: From a total of 743 identified studies, six original studies were eligible for inclusion in the systematic review (median =97 patients). The intraclass correlation coefficient (ICC) for inter-reviewer on total RQS was excellent with 0.99 [95% confidence interval (CI) of 0.946< ICC <0.999]. There were no significant differences in the analyses between each RQS domain and subgroup components (P always >0.05). Numerically higher RQS domains score for publication year ≤2022 than 2023 and number of patients > median than ≤ median but not statistically significant. Conclusions: The number of radiomics studies involving CBCT and MVCT is still very limited. Self-reported RQS assessments should be encouraged for all radiomics studies.

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Background: With the widespread adoption of computed tomography (CT) technology, the number of detected pulmonary nodules has gradually increased. CT-guided percutaneous needle biopsy has become the primary method for qualitative diagnosis of pulmonary nodules. Benefiting from its three-dimensional (3D) reconstruction capability, cone-beam CT (CBCT) technology has also been widely adopted. Nevertheless, pneumothorax remains the most common complication of these diagnostic and therapeutic procedures. This study assessed the diagnostic accuracy of conventional CT (CCT)- and CBCT-guided coaxial core needle biopsy (CCNB) and the effectiveness of gelfoam particle suspension in reducing complications through tract embolization. Methods: A retrospective analysis was conducted on 320 patients who had undergone CCNB for nodules ≤3 cm from January 2020 to June 2022 at Zhongshan People's Hospital, comprising 325 biopsies (145 CCT-guided and 180 CBCT-guided). Gelfoam tract embolization was specifically used in biopsies of patients identified with a high risk of complications. Comparative statistics involved diagnostic outcomes (sensitivity, specificity, accuracy), procedural lengths, complication occurrences, and radiation doses. Results: Diagnostically, both CCT (sensitivity 93.3%, specificity 100%, accuracy 94.1%) and CBCT (sensitivity 92.8%, specificity 100%, accuracy 93.8%) offered a similarly high performance. The CCT technique was preferable in terms of shorter median operational times (19 vs. 24 minutes; P<0.001) and greater radiation exposure (13.9 vs. 10.1 mSv; P<0.001). The complication rates of CBCT and CCT, such as those of pneumothorax (18.9% vs. 20.7%; P=0.69) and hemorrhage (23.9% vs. 18.6%; P=0.25), were comparable. Of note, the comparison of biopsies with and without gelfoam embolization revealed a marked reduction in postoperative pneumothorax incidence (1.24% vs. 7.9%; P=0.004) and the requirement for drainage (0% vs. 4.27%; P=0.02), indicating the effectiveness of this procedure. Conclusions: CCT- and CBCT-guided lung biopsies demonstrate equivalent diagnostic capacities, with CCT providing shorter median operational times. Importantly, gelfoam embolization substantially diminishes the risk of postoperative pneumothorax, underscoring its value in high-risk patients.

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BACKGROUND: The aim of the present study was to determine the presence, frequency, and characteristics of the accessory maxillary ostium (AMO) in a specific Turkish population using cone beam computed tomography (CBCT) and to evaluate the frequency of pathologies and anatomical variations in the nasal cavity and maxillary sinus and to assess their relationship with the AMO. MATERIALS AND METHODS: This study retrospectively evaluated the presence of AMO in CBCT images of 543 patients, the patients' age, gender, and dentition status, the presence of nasal cavity variations and maxillary sinus pathologies, and their relationship to the presence of AMO. Descriptive values of the data and comparative results were included. RESULTS: 249 males and 294 females participated in the study. The majority of right and left sinus pathologies were irregular type mucosal thickenings (right/left; 14%, 14.9%). The majority of nasal variations were concha bullosa (right/left; 37.9%, 39.2%). There were 148 (27.3%) and 138 (25.4%) AMOs on the right and left sides, respectively, with the majority in the middle position (right/left; 21.2%/17.5%). The frequency of right and left AMOs was significantly higher in men (P = 0.019 and P = 0.020, respectively). The left AMO frequency was significantly higher in patients with left-sided sinus pathology (P = 0.003). AMO diameters were larger in men (right/left P = 0.010 and P = 0.021, respectively), and left AMO diameter was significantly larger in patients with left sinus pathology (P = 0.006). CONCLUSIONS: Before any surgical intervention in the maxillary sinus and osteomeatal region, the presence and location of the AMO, existing pathologies, and variations in the region should be carefully checked to avoid complications.

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PURPOSE: Many studies have demonstrated superior performance of Monte Carlo (MC) over type B algorithms in heterogeneous structures. However, even in homogeneous media, MC dose simulations should outperform type B algorithms in situations of electronic disequilibrium, such as small and highly modulated fields. Our study compares MC and Collapsed Cone (CC) dose algorithms in RayStation 12A. Under consideration are 6 MV and 6 MV flattening filter-free (FFF) photon beams, relevant for VMAT plans such as head-and-neck and stereotactic lung treatments with heterogeneities, as well as plans for multiple brain metastases in one isocenter, involving highly modulated small fields. We aim to investigate collimator angle dependence of small fields and performance differences between different combinations of ArcCHECK configuration and dose algorithm. METHODS: Several verification tests were performed, ranging from simple rectangular fields to highly modulated clinical plans. To evaluate and compare the performance of the models, the agreements between calculation and measurement are compared between MC and CC. Measurements include water tank measurements for test fields, ArcCHECK measurements for test fields and VMAT plans, and film dosimetry for small fields. RESULTS AND CONCLUSIONS: In very small or narrow fields, our measurements reveal a strong dependency of dose output to collimator angle for VersaHD with Agility MLC, reproduced by both dose algorithms. ArcCHECK results highlight a suboptimal agreement between measurements and MC calculations for simple rectangular fields when using inhomogeneous ArcCHECK images. Therefore, we advocate for the use of homogeneous phantom images, particularly for static fields, in ArcCHECK verification with MC. MC might offer performance benefits for more modulated treatment fields. In ArcCHECK results for clinical plans, MC performed comparable to CC for 6 MV. For 6 MV FFF and the preferred homogeneous phantom image, MC resulted in consistently better results (13%-64% lower mean gamma index) compared to CC.

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PURPOSE: The presence of metal implants can produce artifacts and distort Hounsfield units (HU) in patient computed tomography (CT) images. The purpose of this work was to characterize a novel metal artifact reduction (MAR) algorithm for reconstruction of CBCT images obtained by the HyperSight imaging system. METHODS: Three tissue-equivalent phantoms were fitted with materials commonly used in medical applications. The first consisted of a variety of metal samples centered within a solid water block, the second was an Advanced Electron Density phantom with metal rods, and the third consisted of hip prostheses positioned within a water tank. CBCT images of all phantoms were acquired and reconstructed using the MAR and iCBCT Acuros algorithms on the HyperSight system. The signal-to-noise ratio (SNR), artifact index (AI), structural similarity index measure (SSIM), peak signal-to-noise ratio (PSNR), and mean-square error (MSE) were computed to assess the image quality in comparison to artifact-free reference images. The mean HU at various VOI positions around the cavity was calculated to evaluate the artifact dependence on distance and angle from the center of the cavity. The artifact volume of the phantom (excluding the cavity) was estimated by summing the volume of all voxels with HU values outside the 5th and 95th percentiles of the phantom CBCT with no artifact. RESULTS: The SNR, AI, SSIM, PSNR, and MSE metrics demonstrated significantly higher similarity to baseline when using MAR compared to iCBCT Acuros for all high-density materials, except for aluminum. Mean HU returned to expected solid water background at a shorter distance from metal sample in the MAR images, and the standard deviation remained lower for the MAR images at all distances from the insert. The artifact volume decreased using the novel MAR algorithm for all metal samples excluding aluminum (p < 0.001) and all hip prostheses (p < 0.05). CONCLUSION: Varian's HyperSight MAR reconstruction algorithm shows a reduction in metal artifact metrics, motivating the use of MAR reconstruction for patients with metal implants.

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BACKGROUND AND PURPOSE: Our goal was to develop a workflow to automatically evaluate delivered dose on daily cone beam computed tomography (CBCT) in all breast cancer patients to assess dosimetric impact of anatomical changes and guide decision-making for offline plan adaptation. MATERIALS AND METHODS: The workflow automatically processes the daily CBCTs of all breast cancer patients receiving local and locoregional radiotherapy. The planning-CT is registered to the CBCT to create a synthetic CT and propagate contours. A forward dose calculation is performed, and DVH parameters are extracted and printed in a report. We evaluated the workflow on a group level and in a subset of 30 patients on a patient-specific level, including comparison to clinical evaluation on additional planning-CT in 10 patients. RESULTS: 7454 fractions in 647 patients were analyzed over a period of seven months. Median breast clinical target volume V95% was ≥95 % for 97 % of the patients. The workflow would have provided useful additional insights for decision-making for the requirement of plan adaptation, based on debatable disagreement with the clinical decision in half of the cases with an additional planning-CT. The workflow also identified cases with suboptimal coverage not identified in the clinical procedure. CONCLUSION: We developed a fully automated workflow for dose evaluation on daily CBCT for local and locoregional breast radiotherapy. We have demonstrated its potential for aiding decision-making for plan adaptation in patients with changing anatomy and its capability to highlight patients that may receive suboptimal treatment and require closer clinical evaluation of treatment quality.

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The primary purpose of this study was to accurately assess linear, volumetric and morphological changes of maxillary teeth roots following multi-segments Le Fort I osteotomy. A secondary objective was to assess whether patient- and/or treatment-related factors might influence root remodeling. A total of 60 patients (590 teeth) who underwent combined orthodontic and orthognathic surgery were studied retrospectively. The multi-segments group included 30 patients who had either 2-segments or 3-segments Le Fort I osteotomy. The other 30 patients underwent one-segment Le Fort I osteotomy. Preoperative, 1 year, and 2 years postoperative cone beam computed tomography (CBCT) scans were obtained. A validated and fully automated method for evaluating root changes in three dimensions (3D) was applied. No statistical significant differences were found between multi-segments and one-segment Le Fort I for linear, volumetric and morphological measurements. The Spearman correlation coefficient revealed a positive relationship between maxillary advancement and root remodeling, with more advancement leading to more root remodeling. This research may allow surgeons to properly assess root remodeling after combined treatment of orthodontics and the different Le Fort I osteotomies.

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OBJECTIVES: In orthognatic surgery, one of the primary determinants for reliable three-dimensional virtual surgery planning (3D VSP) and an accurate transfer of 3D VSP to the patient in the operation room is the condylar seating. Incorrectly seated condyles would primarily affect the accuracy of maxillary-first bimaxillary osteotomies as the maxillary repositioning is dependent on the positioning of the mandible in the cone-beam computed tomography (CBCT) scan. This study aimed to develop and validate a novel tool by utilizing a deep learning algorithm that automatically evaluates the condylar seating based on CBCT images as a proof of concept. MATERIALS AND METHODS: As a reference, 60 CBCT scans (120 condyles) were labeled. The automatic assessment of condylar seating included three main parts: segmentation module, ray-casting, and feed-forward neural network (FFNN). The AI-based algorithm was trained and tested using fivefold cross validation. The method's performance was evaluated by comparing the labeled ground truth with the model predictions on the validation dataset. RESULTS: The model achieved an accuracy of 0.80, positive predictive value of 0.61, negative predictive value of 0.9 and F1-score of 0.71. The sensitivity and specificity of the model was 0.86 and 0.78, respectively. The mean AUC over all folds was 0.87. CONCLUSION: The innovative integration of multi-step segmentation, ray-casting and a FFNN demonstrated to be a viable approach for automating condylar seating assessment and have obtained encouraging results. CLINICAL RELEVANCE: Automated condylar seating assessment using deep learning may improve orthognathic surgery, preventing errors and enhancing patient outcomes in maxillary-first bimaxillary osteotomies.

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Achromatopsia is the most common cone dysfunction syndrome, affecting 1 in 30,000 people. It is an autosomal recessive disorder with a heterogeneous genetic background with variants reported in CNGA3, CNGB3, GNAT2, PDE6C, PDE6H, and ATF6. Up to 90% of achromatopsia patients harbour mutations in CNGA3 or CNB3, which encode for the alpha and beta subunits of the cone cyclic nucleotide-gated (CNG) channel in cone-specific phototransduction. The condition presents at birth or early infancy with poor visual acuity, nystagmus, photophobia, and colour vision loss in all axes. Multimodal retinal imaging has provided insightful information to characterise achromatopsia patients based on their genotype. There is no FDA-approved treatment for achromatopsia; however, studies have reported several preclinical gene therapies with anatomical and functional improvements reported in vivo. There are currently five gene therapy clinical trials registered for human patients at the phase I/II stage and for CNGA3 or CNGB3 causing achromatopsia. This review aims to discuss the genetics of achromatopsia, genotypic and phenotypic correlations in multimodal retinal imaging, and the developments and challenges in gene therapy clinical trials.

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The influence of solvent properties on ion generation by swab spray ionization was investigated. The ability of a variety of solvents of different relative permittivity, surface tension, and viscosity to form a stable and reproducible electrospray was examined. It is demonstrated that in swab spray ionization, a crucial balance between solvent composition, applied potential, and the solvent flow fed to the swab head must be maintained. The solvent composition was found to significantly affect the shape of the Taylor cone and the emerging cone jet, which eventually have an impact on the resulting ion yield. The results indicate that the relative permittivity of solvents measured under standard conditions is the main factor governing jet shaping, and consequently, the ionization efficacy. Short jets, which are required for maximum ion yield, were observed for solvents with relative permittivity εr higher than 25. Solvents exhibiting lower relative permittivity required the addition of 20% to 60% methanol to limit the jet length and to avoid the ineffective dripping pulsation. The observed effects were compared to conventional electrospray ionization and paper spray ionization.

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Objectives: To analyse and document internal root morphological variations in permanent anterior teeth using conebeam computed tomography. METHODS: The cross-sectional, retrospective study was conducted from January 21 to June 19, 2021, at Jinnah Magnetic Resonance Imaging and Body Scan, and comprised data from July to December 2020 related to all the patients who had been referred to the centre for dental cone-beam computed tomography scan. The scans were evaluated at the Radiology Department of the School of Dentistry at Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan. The morphology of the roots and root canals in all permanent anterior teeth was examined. Root canal configuration was categorised using Vertucci's classification. Data was analysed using SPSS 20. RESULTS: Of the 211 patients, 116(55%) were females and 95(45%) were males. The overall mean age was 39.9±1.02 years (range: 15-65 years). All the permanent anterior teeth exhibited a single root, with the exception 2(0.9%) mandibular right and 4(1.9%) left canines which had double roots. Type I root canals were observed in all 211 (100%) maxillary right central incisors, maxillary left central incisors and maxillary left canines. Among maxillary right canines, 208(98.6%) had type-I root canals, and the corresponding value for maxillary right lateral incisors was 209(99.1%), and for maxillary left lateral incisors, the value was 210(99.5%). Root canal polymorphism had no significant association with gender (p>0.05). CONCLUSIONS: The presence of type-I root canal was common in permanent anterior teeth, and there was significant association of root canal polymorphism with gender.

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Introduction: Tooth cervical abrasion (CA) is a prevalent non-carious cervical lesion that poses challenges for accurate diagnosis from periapical radiographs due to difficulties in assessing the lesion's extent, associated bone loss, and pulpal involvement. The presence of overlying bone structures on the palatal side when lesions are located on the buccal side, or vice versa, further complicates radiographic interpretation. So it is important to define the lesions in all three dimensions. Objective: To provide a three-dimensional descriptive classification for cervical abrasion lesions using Cone Beam Computed Tomography (CBCT). Method: A total of 50 patients with cervical abrasion were selected for the study. From these patients, teeth (n = 10) from each of the four different quadrants were chosen. A CBCT scan with a 6 × 6 cm field of view (FOV) was performed, and the DICOM files of the cervical lesions were transferred to 3-D imaging software. The CBCT images of the cervical abrasion lesions were assessed at the level of the deepest point of the lesion along the long axis of the tooth in both axial and sagittal planes. The height (A), buccolingual dimension (B), circumferential spread (C), and remaining dentine thickness (D) were evaluated and classified using new scoring criteria for each dimension. The reliability and reproducibility of the classification were assessed to ensure its clinical applicability. Conclusion: CBCT can be utilized to classify tooth cervical abrasion in endodontics, enhancing diagnosis, analysis, and treatment outcomes. This three-dimensional view facilitates easier communication among clinicians, allows for tailored treatment approaches, and opens new avenues for research.

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BACKGROUND: In modern Hybrid ORs, the synergies of navigation and robotics are assumed to contribute to the optimisation of the treatment in trauma, orthopaedic and spine surgery. Despite promising evidence in the area of navigation and robotics, previous publications have not definitively proven the potential benefits. Therefore, the aim of this retrospective study was to evaluate the potential benefit and clinical outcome of patients treated in a fully equipped 3D-Navigation Hybrid OR. METHODS: Prospective data was collected (March 2022- March 2024) after implementation of a fully equipped 3D-Navigation Hybrid OR ("Robotic Suite") in the authors level 1 trauma centre. The OR includes a navigation unit, a cone beam CT (CBCT), a robotic arm and mixed reality glasses. Surgeries with different indications of the spine, the pelvis (pelvic ring and acetabulum) and the extremities were performed. Spinal and non-spinal screws were inserted. The collected data was analysed retrospectively. Pedicle screw accuracy was graded according to the Gertzbein and Robbins (GR) classification. RESULTS: A total of n = 210 patients (118 m:92f) were treated in our 3D-Navigation Hybrid OR, with 1171 screws inserted. Among these patients, 23 patients (11.0%) arrived at the hospital via the trauma room with an average Injury Severity Score (ISS) of 25.7. There were 1035 (88.4%) spinal screws inserted at an accuracy rate of 98.7% (CI95%: 98.1-99.4%; 911 GR-A & 111 GR-B screws). The number of non-spinal screws were 136 (11.6%) with an accuracy rate of 99.3% (CI95%: 97.8-100.0%; 135 correctly placed screws). This resulted in an overall accuracy rate of 98.8% (CI95%: 98.2-99.4%). The robotic arm was used in 152 cases (72.4%), minimally invasive surgery (MIS) was performed in 139 cases (66.2%) and wound infection occurred in 4 cases (1,9%). Overall, no revisions were needed. CONCLUSION: By extending the scope of application, this study showed that interventions in a fully equipped 3D-Navigation Hybrid OR can be successfully performed not only on the spine, but also on the pelvis and extremities. In trauma, orthopaedics and spinal surgery, navigation and robotics can be used to perform operations with a high degree of precision, increased safety, reduced radiation exposure for the OR-team and a very low complication rate.

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BACKGROUND: Temporomandibular Disorders (TMD) is the dysfunction of group of muscles and bones in the joint area, the main symptoms of TMD are the pain of the chewing muscles and (or) the temporomandibular joints, mandibular movement disorders and joint noise. This study was designed to explore the therapeutic effects following Individual Musculoskeletally Stable (IMS) position stabilization splint therapy for TMD patients using Fricton index, cone beam computed tomography (CBCT) and surface-Electromyogram (sEMG). METHODS: In this study, we enrolled 31 TMD patients (ranging from 18 to 26 years old, including 7 males and 24 females), first Fricton index was used to evaluate the clinical curative effect of TMD with the treatment of IMS stabilization splint; then CBCT was used to observe the TMJ condylar position changes of TMD before and after the treatment of IMS stabilization splint; finally sEMG was used to observe the changes of electromyography of anterior temporalis (AT) and masseter muscles (MM) of TMD before and after the treatment of IMS stabilization splint. RESULTS: The course of treatment was 6-8 months, with an average of 7.6 months. After the IMS stabilization splint treatment, TMD symptoms relieved, especially in pain, mandibular movement disorder, but still slightly inferior in the treatment of joint noise. And there was a statistically significant difference in the anterior and inner joint space, the condyle had the tendency of moving forward and outward. AT presented reduction significantly of EMG value at rest position after treatment. CONCLUSIONS: IMS stabilization splint is a therapeutic reversible treatment for TMD, especially for pain and mandibular movement disorder; it produces effects of forward and outward condylar movement and elimination of the masticatory muscles antagonism.

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Background/Objectives: The aim of this study was to evaluate incidental findings in the mandible after the placement of dental implants using a new cone-beam computed tomography (CBCT) software. Methods: The initial sample consisted of 2872 CBCT scans of patients of both sexes. The parameters evaluated in this study were the location of the implants in the mandible, implant length, anatomical relationship of the implant with the mandibular canal, presence or absence of damage to the adjacent teeth, presence or absence of implant fractures, and presence or absence of bone support. Fisher's exact test was performed to compare the variables. The significance level was set at p = 0.05. Results: Out of 2872 CBCT scans, 214 images of patients with an average age of 44.5 years were included. The most frequent location of the implants was the posterior region (93.5%), with 54% of the implants having a length between 9 and 14 mm. It was found that 92% of the implants were positioned above the mandibular canal. Damage to adjacent teeth was observed, with no correlation with the implant positioning (p = 1.000). In 100% of cases of implants in the anterior region, there was bone support. Fracture was observed in 1.7% of implants with a length between 9 and 14 mm. Conclusions: The installation of implants in the mandible occurs more frequently in the posterior region, with a high presence of bone support and a low incidence of damage to adjacent teeth, anatomical structures, and fractures.

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Cone-beam computed tomography (CBCT) has emerged as a promising tool for the analysis of the upper airway, leveraging on its ability to provide three-dimensional information, minimal radiation exposure, affordability, and widespread accessibility. The integration of artificial intelligence (AI) in CBCT for airway analysis has shown improvements in the accuracy and efficiency of diagnosing and managing airway-related conditions. This review aims to explore the current applications of AI in CBCT for airway analysis, highlighting its components and processes, applications, benefits, challenges, and potential future directions. A comprehensive literature review was conducted, focusing on studies published in the last decade that discuss AI applications in CBCT airway analysis. Many studies reported the significant improvement in segmentation and measurement of airway volumes from CBCT using AI, thereby facilitating accurate diagnosis of airway-related conditions. In addition, these AI models demonstrated high accuracy and consistency in their application for airway analysis through automated segmentation tasks, volume measurement, and 3D reconstruction, which enhanced the diagnostic accuracy and allowed predictive treatment outcomes. Despite these advancements, challenges remain in the integration of AI into clinical workflows. Furthermore, variability in AI performance across different populations and imaging settings necessitates further validation studies. Continued research and development are essential to overcome current challenges and fully realize the potential of AI in airway analysis.

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This study aimed to evaluate the pathological factors and anatomical variations in the maxillary sinus in patients undergoing dental implant treatment using cone beam computed tomography (CBCT). CBCT, as a key imaging technique in dentistry, offers high-resolution images to assess bone morphology and quality, crucial for preoperative dental implant planning. MATERIAL AND METHODS: The study included a cohort of 200 patients recommended for CBCT as part of their preoperative evaluation. The methodology involved detailed CBCT image analysis to identify and document various anatomical variations due to pneumatization, exostosis, hypoplasia, polyps, cysts, foreign bodies, and anthroliths within the maxillary sinus. RESULTS: Pneumatization was the most common variation, present in 77.5% of subjects. Polypoid lesions were found in 17.5% of patients, with a higher prevalence in younger age groups (57.1% in ages 20-35). Cysts and polyps affected 17.5% of subjects, predominantly males (65.7%). Anthroliths were observed in a minimal percentage (2%), and foreign bodies were found in 1.5% of the patients. Positive correlations were observed between the patient's age and both mucosal thickness and polypoid lesions and between the patient's gender and bone thickening (p-values < 0.05). CONCLUSIONS: The study concluded that CBCT is essential in the preoperative assessment of the maxillary sinus in dental implant candidates due to its superior imaging capabilities, allowing for the identification of critical anatomical variations and pathologies. This thorough evaluation is imperative to ensure the success of implant placement and to mitigate potential complications. However, further research with larger, more diverse populations is recommended to confirm these findings.