RESUMEN

Bromotryptophan is a nonstandard amino acid that is rarely incorporated in ribosomally synthesized and post-translationally modified peptides (ribosomal peptides). Bromotryptophan and its analogs sometimes occur in non-ribosomal peptides. This paper presents an overview of ribosomal and non-ribosomal peptides that are known to contain bromotryptophan and its analogs. This work further covers the biological activities and therapeutic potential of some of these peptides.

Asunto(s)

Mezclas Complejas/química , Péptidos/química , Triptófano/análogos & derivados , Triptófano/química , Secuencia de Aminoácidos , Aminoácidos/química , Animales , Conotoxinas/química , Biología Marina , Procesamiento Proteico-Postraduccional , Ribosomas/química