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1.
Drug Discov Today ; 29(4): 103937, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38430964

RESUMEN

Pharmaceutical managers have been encouraged to look to acquisitions and alliances for innovation. However, the literature warns that the capacity of a company to 'absorb' new knowledge is limited. Here, we introduce corporate divestitures as a tool for freeing up managerial attention. We build a sample of 349 companies, which announced 1784 divestitures and filed 63523 patents, over a 15-year period. We show that innovating companies that divest more produce more and improved patents, and those that divest to create corporate focus also produce more breakthroughs. In doing so, we introduce divestitures as an innovation tool, highlight the importance of the absorptive capacity of a company when discussing innovation, and add nuance to the discussion on external tools for innovation.


Asunto(s)
Preparaciones Farmacéuticas
2.
Front Psychol ; 14: 1097936, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-36874849

RESUMEN

Compared with incremental innovation, breakthrough innovation is essential to sustaining competitive advantage, but breakthrough innovation has the characteristics of high standards and strict requirements. As the main body and foundation of enterprises, the attitude and behavior of employees play a vital role in enterprise innovation. Based on the positive organizational behavior theory and knowledge management theory, the purpose of this paper is to investigate the relationship between psychological capital and breakthrough innovation, and we also integrate tacit knowledge sharing and task interdependence into the research framework, so as to further explore the influence mechanism of employees' psychological capital on breakthrough innovation. Utilizing a quantitative method, this study takes employees of Yunnan coffee enterprises as investigation objects, the data was analyzed using regression analysis through SPSS 24.0, and the existence of mediation was further verified by Bootstrap test. The results showed that the psychological capital of employees have a positive impact on breakthrough innovation; tacit knowledge sharing partially mediates the relationship between psychological capital and breakthrough innovation; and task interdependence plays a moderating role, that is, the stronger the task interdependence, the stronger the influence of employee psychological capital on breakthrough innovation. This study enriches the research on the influencing factors of breakthrough innovation of Yunnan coffee industry, expands the application scenarios of the related theory, emphasizes that the importance of psychological capital and the breakthrough innovation is the result of the interaction and value-added linkage of various internal and external resources.

3.
Front Psychol ; 13: 974569, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36148128

RESUMEN

Purpose: As a new human resource management practice, idiosyncratic deals are personalized employment arrangements negotiated between employees and employers and intended to benefit them both. It plays an important role in attracting, retaining and motivating employees to promote breakthrough innovation. Based on the input-process-output (I-P-O) model, this paper examines the relationship between team idiosyncratic deals and team breakthrough innovation, the mediating role of team exploratory-exploitative knowledge sharing, and the moderating roles of team transactive memory systems and team cognitive flexibility. Participants and methods: In order to reduce the effects of common method biases and causal lag effect, this study is divided into three stages for data collection, with a time interval of 1 month. Eighty teams (406 employees) from six enterprises in Shanghai and Hangzhou were selected as samples, and the hypothesis test was carried out by hierarchical regression analysis, bootstrap, and Johnson-Neyman method. Results: The results show that higher team idiosyncratic deals are associated with higher team breakthrough innovation through higher team exploratory-exploitative knowledge sharing, and that team transactive memory systems and team cognitive flexibility positively moderate the mediating effect of team exploratory-exploitative knowledge sharing in the relationship between team idiosyncratic deals and team breakthrough innovation in the first stage and the second stage, respectively. Under the joint effect of high team transactive memory systems and high team cognitive flexibility, the mediating effect of team exploratory-exploitative knowledge sharing is stronger. Conclusion: The research results break through the previous research framework of social exchange theory, and I-P-O model to explore the influence mechanism of team idiosyncratic deals, in order to promote the sustainable growth of team breakthrough innovation through this non-standard work arrangement. It is hoped that this research can inspire modern enterprises to create team idiosyncratic deals for valuable teams engaged in breakthrough innovation, which are more conducive to give full play to their heterogeneous talents, and finally help enterprises break through the industry bottleneck and win the market competition.

4.
J Technol Transf ; 47(6): 1948-1973, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-34611378

RESUMEN

The purpose of this paper is to examine biopharma innovation ecosystems (IEs) through the lenses of a stakeholder model. In doing so, this work aims to answer the following research question: which stakeholders are required in an IE within biopharma industry and what are their main roles in the IE value creation. The research strategy was designed according to the grounded theory methodology. By applying this methodology, data were collected through verbatim interviews with several stakeholders. Both data collection and data analysis phases were carried out concurrently up to saturation where all data were identified and their consistency across the many forms was reached. The thesis of the paper intends to prove that biopharma IEs consist of a multilevel and longitudinal set of key stakeholders. Furthermore, by investigating the Lombardy case study, it explains the role of each stakeholder with regards to the comparative advantages required in the engagement with the IE. In addition, arising from a holistic view of the biopharma IEs, this research traces the biopharma IE dynamics through the analysis of the IE's driving forces. This paper represents one of the first heuristic attempts to analyze in-depth biopharma IE from a holistic perspective. The paper findings can be considered to be an impactful extension to biopharma IEs world-wide. This broader scope is well supported by expert interviews as a central part of the methodology and by the investigated scientific literature.

5.
Front Psychol ; 13: 1084090, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36726493

RESUMEN

Breakthrough innovation is the focus of the society in the era of knowledge economy. Employee innovation of the enterprises is the starting point of enterprise innovation behavior, and it is the result of the combination of complex psychological capital. Meanwhile, breakthrough innovation often comes from the result of knowledge sharing brought by teamwork. At present, existing studies mainly reveal the influence of knowledge and knowledge structure on the performance of radical innovation. However, the relationship between psychological capital, knowledge sharing and the breakthrough innovation performance needs to be systematically studied. Therefore, this study adopted a research approach, that is, statistical analyses were performed by using SPSS Version 18 and AMOS version 26 (Statistical analyses performed by using SPSS Version 18 and AMOS version 26).This study collected data on employees of 345 different new high-tech enterprises to explore the mechanism by which psychological capital and knowledge sharing affects the breakthrough innovation performance. The research results respond to a positive correlation between psychological capital and knowledge sharing affects the breakthrough innovation performance. Moreover, knowledge sharing has a mediating effect on the effect of psychological capital on breakthrough innovation performance, and the effect is weakened. which is of great theoretical significance for exploring the relationship between psychological capital and knowledge sharing affects the breakthrough innovation performance.

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