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1.
J Technol Pers Disabil ; 12: 58-75, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39286467

RESUMEN

Interest in the benefits of braille for people who are blind is high among professionals in the blindness field, but we know little about how braille is used in the workplace. The broad purpose of this study was to learn how employed people who are blind use braille on the job. Specific topics investigated included: work tasks refreshable braille technology (RBT) is used for, personal and job characteristics of RBT users compared to non-users, and factors associated with RBT use among workers with at least moderate braille skills. This study utilized data from 304 participants in a longitudinal research project investigating assistive technology use in the workplace by people who are blind. Two-thirds of our participants used braille on the job, and more than half utilized RBT. Workers who used RBT did not necessarily use it for all computer-related tasks they performed. RBT use was generally not significantly related to job characteristics, except for working for a blindness organization. RBT use was not significantly related to general personal characteristics but it was significantly different based on disability-related characteristics. Only older age and higher braille skills were significantly associated with RBT use on the job in a multivariate logistic regression model.

2.
Neuroimage ; : 120852, 2024 Sep 10.
Artículo en Inglés | MEDLINE | ID: mdl-39265958

RESUMEN

Natural Braille reading presents significant challenges to the brain networks of late blind individuals, yet its underlying neural mechanisms remain largely unexplored. Using natural Braille texts in behavioral assessments and functional MRI, we sought to pinpoint the neural pathway and information flow crucial for Braille reading performance in late blind individuals. In the resting state, we discovered a unique neural connection between the higher-order 'visual' cortex, the lateral occipital cortex (LOC), and the inferior frontal cortex (IFC) in late blind individuals, but not in sighted controls. The left-lateralized LOC-IFC connectivity was correlated with individual Braille reading proficiency. Prolonged Braille reading practice led to increased strength of this connectivity. During a natural Braille reading task, bidirectional information flow between the LOC and the IFC was positively modulated, with a predominantly stronger top-down modulation from the IFC to the LOC. This stronger top-down modulation contributed to higher Braille reading proficiency. We thus proposed a two-predictor multiple regression model to predict individual Braille reading proficiency, incorporating both static connectivity and dynamic top-down communication between the LOC-IFC link. This work highlights the dual contributions of the occipito-frontal neural pathway and top-down cognitive strategy to superior natural Braille reading performance, offering guidance for training late blind individuals.

3.
Cureus ; 16(8): e66708, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-39262514

RESUMEN

The aim of this study was to compare the effectiveness of audio-tactile performance (ATP) versus other oral health education methods in improving the oral health status of visually challenged children and adolescents. The review was carried out based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A systematic search was performed on the effectiveness of ATP in improving the oral health of visually impaired children. The search was conducted in Scopus, Google Scholar, PubMed, Embase, Lilacs, Web of Science, and Cochrane until December 2022. The risk-of-bias tool for randomized trials (RoB-2) was used to analyze the risk of bias. Meta-analysis was carried out for included studies that made similar comparisons and reported the same outcome measures. The initial search retrieved 368 records, of which nine studies were included for qualitative synthesis. Out of the nine included studies, five studies were included for quantitative synthesis. Two studies evaluating plaque index at 180 days (MD = -0.10; p = 0.0009; CI = -0.17 to -0.02) and five studies evaluating gingival index at 90 days (MD = -0.15; p < 0.00001; CI= -0.21 to -0.09) exhibited a significant mean difference favoring ATP. Three studies that evaluated gingival index at 30 days and 180 days showed significant mean differences (MD = -0.27; p < 0.000; CI = -0.40 to -0.15 and MD = -0.09; p = 0.01; CI= -0.15 to -0.02) favoring ATP. The ATP technique produced significant improvements in oral health when compared with other conventional techniques. However, the studies had high heterogeneity, and hence, the result must be inferred with caution.

4.
Pharmaceuticals (Basel) ; 17(8)2024 Aug 01.
Artículo en Inglés | MEDLINE | ID: mdl-39204122

RESUMEN

An innovative approach for creating customized dosage forms and supporting patient populations with specific requirements who need additional support to improve drug adherence is 3D printing. This work introduces liquid crystal display (LCD) 3D printing as a means of developing melatonin (MLT) tablets. For patients who are blind or visually challenged, Braille patterns were displayed on the tablet surface in addition to the optimization of printing hydrogel inks. Owing to the great printing accuracy, blind patients could validate the Braille patterns that provided the required information. Upon further examination MLT was found to be present in the photopolymerized resins in an amorphous state. The choice of poly(ethylene glycol)-diacrylate (PEGDA) with varying molecular weights and the inclusion of surfactants or solubilizers interfered with the photopolymerization of the resin, hence controlling the rates of MLT dissolution towards the sought sustained release. Nuclear magnetic resonance (NMR) analysis showed that photopolymerization of the PEGDA resins in the printed dosage forms has taken place. A small batch scale-up investigation showed that LCDs could print a significant number of tablets quickly-about twenty-four minutes.

5.
Int J Pharm ; 663: 124594, 2024 Sep 30.
Artículo en Inglés | MEDLINE | ID: mdl-39154920

RESUMEN

3D printing has been introduced as a novel approach for the design of personalized dosage forms and support patient groups with special needs that require additional assistance for enhanced medication adherence. In this study liquid crystal display (LCD) is introduced for the development of sustained release bupropion.HCl printed tablets. The optimization of printing hydrogel inks was combined with the display of Braille patterns on the tablet surface for blind or visually impaired patients. Due to the high printing accuracy, the Braille patterns could be verified by blind patients and provide the required information. Further characterization revealed the presence of BUP in amorphous state within the photopolymerized resins. The selection of poly(ethylene glycol) (PEG)-diacrylate (PEGDA) of different molecular weights and the presence of surfactants or solubilizers disrupted the resin photopolymerization, thus controlling the BUP dissolution rates. A small batch scale-up study demonstrated the capacity of LCD to print rapidly a notable number of tablets within 24 min.


Asunto(s)
Bupropión , Preparaciones de Acción Retardada , Liberación de Fármacos , Polietilenglicoles , Impresión Tridimensional , Comprimidos , Bupropión/química , Bupropión/administración & dosificación , Polietilenglicoles/química , Humanos , Cristales Líquidos/química , Solubilidad
6.
J Pharm Bioallied Sci ; 16(Suppl 2): S1721-S1725, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38882738

RESUMEN

To compare the effectiveness of various modes of oral health education in visually impaired children. A total of 100 students aged 8-15 years were included. The children were divided randomly into four groups. Children in Group I received oral hygiene instructions through Braille pamphlets. In Group II, children received instructions through nonvisual desktop access (NVDA). For children in Group III, both Braille and NVDA were used to deliver the instructions. Children included in Group IV served as controls, who did not receive any information in any form for the study period. After oral examination to record plaque and OHI-S scores, a questionnaire was given to the children to assess their knowledge scores. The same questionnaire was repeated after 1 month to reassess the knowledge score in different groups. Chi-square test, Wilcoxon test, and post hoc analysis tests were used. The mean plaque scores among the control group children at the follow-up were significantly higher (2.5 ± 0.64) than any other group. Similarly, the control group had higher mean oral hygiene simplified scores (1.75 ± 1.32) than the Braille (1.12 ± 0.65), NVDA (0.85 ± 1.38), and Braille + NVDA (0.2 ± 0.64) groups at follow-up. With regards to the mean total knowledge score, the control group scored the least (2.16 ± 1.46), while the Braille, NVDA, and Braille + NVDA groups scored 3.16 ± 1.43, 4.52 ± 1.12, and 6.36 ± 0.52, respectively. Combination of Braille and NVDA was found to be effective in educating and motivating visually impaired children regarding maintenance of oral hygiene.

7.
Adv Sci (Weinh) ; 11(26): e2400479, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38696643

RESUMEN

Electronic skins are expected to replicate a human-like tactile sense, which significantly detects surface information, including geometry, material, and temperature. Although most texture features can be sensed in the horizontal direction, the lack of effective approaches for detecting vertical properties limits the development of artificial skin based on tactile sensors. In this study, an all-printed finger-inspired tactile sensor array is developed to realize the 3D detection and reconstruction of microscale structures. A beam structure with a suspended multilayer membrane is proposed, and a tactile sensor array of 12 units arranged in a dual-column layout is developed. This architecture enables the tactile sensor array to obtain comprehensive geometric information of micro-textures, including 3D morphology and clearance characteristics, and optimizes the 3D reconstruction patterns by self-calibration. Moreover, an innovative screen-printing technology incorporating multilayer printing and sacrificial-layer techniques is adopted to print the entire device. In additon, a Braille recognition system utilizing this tactile sensor array is developed to interpret Shakespeare's quotes printed in Grade 2 Braille. The abovementioned demonstrations reveal an attractive future vision for endowing bioinspired robots with the unique capability of touching and feeling the microscale real world and reconstructing it in the cyber world.

8.
J Pharm Bioallied Sci ; 16(Suppl 1): S97-S101, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38595616

RESUMEN

To assess how oral health education (OHE) techniques using braille affect visually impaired children's awareness of oral health, oral hygiene status and practices, plaque, gingival health, and dental caries status. From 2010 to 2020, a thorough literature search will be conducted for studies in the English language using PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, Google Scholar, and Open Grey. Data extraction will be done after two reviewers extensively evaluate the papers for qualifying requirements. In accordance with the research designs, a quality evaluation of the chosen studies will be conducted. With the use of the program Review Manager 5.3, a meta-analysis will be completed.

9.
IEEE Open J Eng Med Biol ; 5: 205-209, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38606396

RESUMEN

Braille is often proposed by the uninformed as the optimal solution to providing an alternative to visual information to the visually impaired. The purpose of this article is to highlight the complexity of the braille user population and discuss the importance of understanding the use of braille as a solution for equal access of information. As part of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) Rapid Acceleration of Diagnostics (RADx) Tech program and its goal to make home tests accessible to people with disabilities, a series of interviews with industry experts was conducted to better understand braille technologies and the braille user space. Published literature findings provided additional context and support to these interviews. It was found that expert consensus and data from published literature vary. The braille user population is complex and lacks consistent characterization. Visually printed media should not be solely relied on to communicate information. In conclusion, braille is one solution for improving access to information. Understanding the unique needs of braille users and how they engage with information in a world that is heavily reliant on visual content, is a critical step in developing and implementing non-visual alternatives that will collectively address information access.

10.
Adv Mater ; 36(24): e2313518, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38502121

RESUMEN

A wearable Braille-to-speech translation system is of great importance for providing auditory feedback in assisting blind people and people with speech impairment. However, previous reported Braille-to-speech translation systems still need to be improved in terms of comfortability or integration. Here, a Braille-to-speech translation system that uses dual-functional electrostatic transducers which are made of fabric-based materials and can be integrated into textiles is reported. Based on electrostatic induction, the electrostatic transducer can either serve as a tactile sensor or a loudspeaker with the same design. The proposed electrostatic transducers have excellent output performances, mechanical robustness, and working stability. By combining the devices with machine learning algorithms, it is possible to translate the Braille alphabet and 40 commonly used words (extensible) into speech with an accuracy of 99.09% and 97.08%, respectively. This work demonstrates a new approach for further developments of advanced assistive technology toward improving the lives of disabled people.


Asunto(s)
Electricidad Estática , Textiles , Humanos , Dispositivos Electrónicos Vestibles , Habla , Diseño de Equipo , Auxiliares Sensoriales , Aprendizaje Automático
11.
Heliyon ; 10(4): e26155, 2024 Feb 29.
Artículo en Inglés | MEDLINE | ID: mdl-38390067

RESUMEN

For many years, braille-assistive technologies have aided blind individuals in reading, writing, learning, and communicating with sighted individuals. These technologies have been instrumental in promoting inclusivity and breaking down communication barriers in the lives of blind people. One of these technologies is the Optical Braille Recognition (OBR) system, which facilitates communication between sighted and blind individuals. However, current OBR systems have a gap in their ability to convert braille documents into multilingual texts, making it challenging for sighted individuals to learn braille for self-learning-based uses. To address this gap, we recommend a segmentation and deep learning-based approach named Fly-LeNet that converts braille images into multilingual texts. The approach includes image acquisition, preprocessing, and segmentation using the Mayfly optimization approach with a thresholding method and a braille multilingual mapping step. It uses a deep learning model, LeNet-5, that recognizes braille cells. We evaluated the performance of the Fly-LeNet through several experiments on two datasets of braille images. Dataset-1 consists of 1404 labeled samples of 27 braille signs demonstrating the alphabet letters, while Dataset-2 comprises 5420 labeled samples of 37 braille symbols representing alphabets, numbers, and punctuations, among which we used 2000 samples for cross-validation. The suggested model achieved a high classification accuracy of 99.77% and 99.80% on the test sets of the first and second datasets, respectively. The results demonstrate the potential of Fly-LeNet for multilingual braille transformation, enabling effective communication with sighted individuals.

12.
ACS Nano ; 18(1): 1157-1171, 2024 Jan 09.
Artículo en Inglés | MEDLINE | ID: mdl-38147575

RESUMEN

Exploring flexible tactile sensors capable of recognizing surface information is significant for the development of virtual reality, artificial intelligence, soft robotics, and human-machine interactions (HMI). However, it is still a challenge for current tactile sensors to efficiently recognize the surface pattern information while maintaining the simplicity of the overall system. In this study, cantilever beam-like magnetized micropillars (MMPs) with height gradients are assembled as a position-registered array for rapid recognition of surface pattern information. After crossing the surface location with convex patterns, the deformed MMPs undergo an intrinsic oscillating process to induce damped electrical signals, which can then be converted to a frequency domain for eigenfrequency extraction. Via precisely defining the specific eigenfrequencies of different MMPs, position mapping is realized in crosstalk-free behavior even though all signals are processed by one communication channel and a pair of electrodes. With a customized LabVIEW program, the surface information (e.g., letters, numbers, and Braille) can be accurately reconstructed by the frequency sequence produced in a single scanning procedure. We expect that the proposed interface can be a convenient and powerful platform for intelligent surface information perception and an HMI system in the future.

13.
Spec Care Dentist ; 2023 Nov 14.
Artículo en Inglés | MEDLINE | ID: mdl-37964052

RESUMEN

INTRODUCTION: Individuals with visual impairment (VI) are doubly disadvantaged by their lack of vision and poor oral hygiene (OH). Implementing oral health education (OHE) interventions should be set as goals to improve OH status and prevent oral diseases. However, few studies have examined the specific teaching method of OH skills. This study aimed to identify the most influential OHE interventions enabling individuals with VI worldwide, especially those in countries where VI is most frequent, to maintain OH and improve knowledge and practices. METHODS: An extensive literature review was conducted using the Preferred Reporting Items for Systematic Review and Meta-Analysis method. This study systematically searched electronic databases (PubMed via Medline, Cochrane, Embase, and Google Scholar) using expert-validated keywords, complemented by manual searches, to identify relevant articles published between April 1, 2012, and September 30, 2022. RESULT: PICOS criteria were formulated for study inclusion. The bibliographical search identified 1485 articles, which were subsequently filtered. Two researchers separately screened the articles for eligibility and to reduce the risk of bias in the included studies. Finally, the most pertinent 21 articles were scrutinized for data synthesis. CONCLUSION: Most studies identified combination methods, including customized educational demonstrations, as the best at improving OH status, knowledge, and practices. However, long-term, rigorously designed, and effective patient-centered communication trials, including those on innovative methods, are still needed for individuals with VI.

14.
Stud Health Technol Inform ; 306: 272-277, 2023 Aug 23.
Artículo en Inglés | MEDLINE | ID: mdl-37638925

RESUMEN

A blind student writes and submits reports in Braille word processor, which is difficult for teachers to read. This study's purpose is to make a translator from Braille into mixed Kana-Kanji sentences for such teachers. Because Kanji has homonyms, it is not always possible to get correct results when converting. To overcome this difficulty, we used deep learning for translation. We built a training dataset composed from 15,000 pairs of Braille codes and mixed Kana-Kanji sentences, and a validation dataset. In training, we got an accuracy of 0.906 and a good Bleu score of 0.600. In validation, we found 5 mistaken words in selecting homonymous Kanji by examining translation mistakes from 100 pairs of the verification sentences. The choice of homonymous Kanji depends on the context. For decreasing such type of errors, it is necessary to introduce of translation of paragraphs by increasing the scale of the network model in deep learning, and to expand the network structure.


Asunto(s)
Ceguera , Aprendizaje Profundo , Lenguaje , Lectura , Auxiliares Sensoriales , Humanos , Fonética , Traducciones , Japón , Enseñanza
15.
Neuroimage ; 278: 120296, 2023 09.
Artículo en Inglés | MEDLINE | ID: mdl-37495199

RESUMEN

Learning letter and speech sound (LS) associations is a major step in reading acquisition common for all alphabetic scripts, including Braille used by blind readers. The left superior temporal cortex (STC) plays an important role in audiovisual LS integration in sighted people, but it is still unknown what neural mechanisms are responsible for audiotactile LS integration in blind individuals. Here, we investigated the similarities and differences between LS integration in blind Braille (N = 42, age range: 9-60 y.o.) and sighted print (N = 47, age range: 9-60 y.o.) readers who acquired reading using different sensory modalities. In both groups, the STC responded to both isolated letters and isolated speech sounds, showed enhanced activation when they were presented together, and distinguished between congruent and incongruent letter and speech sound pairs. However, the direction of the congruency effect was different between the groups. Sighted subjects showed higher activity for incongruent LS pairs in the bilateral STC, similarly to previously studied typical readers of transparent orthographies. In the blind, congruent pairs resulted in an increased response in the right STC. These differences may be related to more sequential processing of Braille as compared to print reading. At the same time, behavioral efficiency in LS discrimination decisions and the congruency effect were found to be related to age and reading skill only in sighted participants, suggesting potential differences in the developmental trajectories of LS integration between blind and sighted readers.


Asunto(s)
Fonética , Percepción Visual , Humanos , Niño , Adolescente , Adulto Joven , Adulto , Persona de Mediana Edad , Percepción Visual/fisiología , Mapeo Encefálico , Ceguera , Aprendizaje , Lectura
16.
Spec Care Dentist ; 43(5): 656-665, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37415089

RESUMEN

INTRODUCTION: Young adults with Visual impairment (VI) challenge the dentists' skills and knowledge due to a higher risk of developing oral diseases due to difficulty in attaining good oral hygiene (OH). AIMS: To assess the effectiveness of ATP (Audio-Tactile Performance) technique and braille versus braille alone in improving OH status of young adults with VI. METHODS AND MATERIAL: A parallel arm, randomized controlled trial was conducted among 70 young adults with VI. Participants were randomly allocated to either test group (braille combined with ATP) or control group (braille alone). A pre-validated braille questionnaire was used to obtain the baseline data followed by clinical examination. OH status assessment was recorded through Gingival Index (GI) and Plaque Index (PI) proforma followed by a thorough ultrasonic oral prophylaxis. Periodic reinforcement was carried out on the 7th day, after 1 month and 3 months. The outcomes were assessed at the end of 3rd and 6th month. RESULTS: There was an increase in the knowledge scores after 3 and 6 months and attitude scores, GI scores and PI scores after 6 months in the test group compared to the control group and this difference was found to be statistically significant. CONCLUSIONS: The findings of this study showed that a combination of ATP and braille proved to be more effective than braille alone in improving the knowledge and OH status of young adults with VI.


Asunto(s)
Educación en Salud Dental , Higiene Bucal , Humanos , Adulto Joven , Educación en Salud Dental/métodos , Encuestas y Cuestionarios , Trastornos de la Visión , Adenosina Trifosfato
17.
Disabil Rehabil Assist Technol ; : 1-16, 2023 Jun 27.
Artículo en Inglés | MEDLINE | ID: mdl-37368974

RESUMEN

PURPOSE: Braille use has been linked to higher rates of employment, education, financial self-sufficiency, and self-esteem. One area of the world particularly impacted by braille illiteracy is the Philippines. In 2016, Digital Learning for Development and All Children Reading released a "Grand Challenge for Development" that challenged researchers to address the need for assistive technologies to help children with sensory disabilities learn to read in the Philippines. The purpose of this research was to identify technical specifications, and then co-design and test a device that could be used both in developed and developing countries, specifically Canada and the Philippines. METHODS: An iterative, co-design process was undertaken to develop a prototypical device, BrailleBunny. The extent to which the device fulfilled the design criteria and directions for future development were determined through a series of case studies with 25 end-users. RESULTS: The prototypical device requires improvement in financial accessibility, durability and reliability. All other criteria were met. CONCLUSIONS: Despite identified areas for improvement, the user feedback was positive, with the majority of users identifying that this device could provide transferrable learning to standard-size braille. With improvements, BrailleBunny, could be a valuable tool to increase the uptake of learning braille in the Philippines.Implications for RehabilitationAn inexpensive device, BrailleBunny was developed to promote transferable braille literacy skills including writing with a slate and stylus for children learning to read.The BrailleBunny provides real-time auditory and tactile feedback, and functions in either English or Tagalog (the languages which are taught in the Filipino curriculum).Feedback from 25 children and adults indicated the potential for use within schools in both Canada and the Philippines.

18.
Stud Health Technol Inform ; 303: 36-44, 2023 Jun 22.
Artículo en Inglés | MEDLINE | ID: mdl-37347602

RESUMEN

Since our PhD, we aim to rethink the transposition of universal design (UD) in museums for narratives, specifically on labels. We have conceptualised a model of universal label, adding inclusive and communicative writing: inclusive, by using universal design merging on the same device several forms of communication (sign language, Braille, easy to read); communicative, because it explains and learns how citizens perceived as disabled communicate. UD writing could initiate and encourage communication. In this paper, we applied our reflections on UD writing to the label of The Mona Lisa at the Louvre Museum.


Asunto(s)
Personas con Discapacidad , Museos , Humanos , Comunicación , Narración , Escritura
19.
J Cogn ; 6(1): 21, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37152833

RESUMEN

The sense of touch is underrepresented in cognitive psychology research. One of the reasons is that controlling the timing of stimulus presentation, which is a hallmark of cognitive research, is significantly more difficult for tactile stimuli than visual or auditory stimuli. In the present work, we present a system to display tactile stimuli (braille cells) and collect response time with the capability for static and dynamic (passive haptic) stimuli prsentation that will contribute to the development of tactile research. While the system requires some construction, it can be put together with commercially available materials. Here, we present the step-by-step instructions for constructing the tool, the code used to control it, and some basic experiments to validate it. The data from the experiments show that the device can be used for a variety of tactile perception experiments.

20.
Cortex ; 162: 65-80, 2023 05.
Artículo en Inglés | MEDLINE | ID: mdl-37003099

RESUMEN

The Triple-Code Model stipulates that numerical information from different formats and modalities converges on a common magnitude representation in the Intraparietal Sulcus (IPS). To what extent the representations of all numerosity forms overlap remains unsolved. It has been postulated that the representation of symbolic numerosities (for example, Arabic digits) is sparser and grounded in an existing representation that codes for non-symbolic numerosity information (i.e., sets of objects). Other theories argue that numerical symbols represent a separate number category that emerges only during education. Here, we tested a unique group of sighted tactile Braille readers with numerosities 2, 4, 6 and 8 in three number notations: Arabic digits, sets of dots, tactile Braille numbers. Using univariate methods, we showed a consistent overlap in activations evoked by these three number notations. This result shows that all three used notations are represented in the IPS, which may suggest at least a partial overlap between the representations of the three notations used in this experiment. Using MVPA, we found that only non-automatized number information (Braille and sets of dots) allowed successful number classification. However, the numerosity of one notation could not be predicted above chance from the brain activation patterns evoked by another notation (no cross-classification). These results show that the IPS may host independent number codes in overlapping cortical circuits. In addition, they suggest that the level of training in encoding a given type of number information is an important factor that determines the amount of exploitable information and needs to be controlled for in order to identify the neural code underlying numerical information per se.


Asunto(s)
Lenguaje , Imagen por Resonancia Magnética , Humanos , Imagen por Resonancia Magnética/métodos , Lóbulo Parietal/fisiología , Tacto , Mapeo Encefálico
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