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Introducción. El manejo perioperatorio de las urgencias hepatobiliares por parte del cirujano general es una competencia esperada y se considera un reto por su relativa frecuencia, impacto en la salud del individuo y la economía, así como las implicaciones en el ejercicio clínico confiable y de alta calidad. Se desconocen los aspectos formales de la educación en cirugía hepatobiliar para el cirujano general en Colombia. El objetivo del presente estudio fue explorar la perspectiva de los cirujanos hepatobiliares sobre esta problemática. Métodos. Se realizó un estudio cualitativo, mediante entrevistas semiestructuradas con 14 especialistas en cirugía hepatobiliar colombianos, en donde se exploraron los desafíos del entrenamiento, el tiempo y las características de una rotación, la evaluación de la confiabilidad, el número de procedimientos y el rol de la simulación. Se hizo un análisis temático de la información. Resultados. Los expertos mencionaron la importancia de la rotación obligatoria por cirugía hepatobiliar para los cirujanos en formación. El tiempo ideal es de tres meses, en el último año de residencia, en centros especializados, con exposición activa y bajo supervisión. Conclusiones. Por las características epidemiológicas del país y la frecuencia de enfermedades hepatobiliares que requieren tratamiento quirúrgico, es necesario que el cirujano general cuente con una formación sólida en este campo durante la residencia. El presente estudio informa sobre las características ideales del entrenamiento en este campo desde la visión de los expertos colombianos.
Introduction. The perioperative management of hepatobiliary emergencies by the general surgeon is an expected competence and is considered a challenge due to its relative frequency, impact on the individual health and the economy, as well as the implications for reliable and high-quality clinical practice. The formal aspects of education in hepatobiliary surgery for the general surgeon in Colombia are unknown. The objective of the present study was to explore the perspective of hepatobiliary surgeons on this problem. Methods. A qualitative study was carried out through semi-structured interviews with 14 Colombian hepatobiliary surgery specialists, where the challenges of training, time and characteristics of the rotation, evaluation of reliability, number of procedures and role of simulation. A thematic analysis of the information was carried out. Results. The experts mentioned the importance of mandatory rotation for hepatobiliary surgery for surgeons in training. The ideal duration was three months, during the last year of residency, in specialized centers with active exposure and under supervision. Conclusions. Due to the epidemiological characteristics of the country and the frequency of hepatobiliary diseases that require surgical treatment, it is necessary for the general surgeon to have solid training in this field during residency. The present study reports on the ideal characteristics of training in this field from the perspective of Colombian experts.
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Humanos , Procedimientos Quirúrgicos del Sistema Biliar , Educación de Postgrado en Medicina , Cirugía General , Enfermedades de las Vías Biliares , Tratamiento de Urgencia , Entrenamiento SimuladoRESUMEN
Bariatric patients are at risk for developing biliary stones. Choledocholithiasis poses a significant challenge in Roux-en-Y gastric bypass patients due to anatomical changes, complicating the treatment. We present a case of a 71-year-old female with recurrent choledocholithiasis post-bariatric surgery. After failed endoscopic attempts, a biliodigestive bypass with choledocoduodenal anastomosis was performed successfully using the Da Vinci robotic platform. This technique offers a single anastomosis, excluding the duodenum from transit, preventing food reflux. The patient had an uneventful recovery with no recurrence after 1 year. The choledocoduodenal anastomosis is a viable option for biliary diversion in patients with challenging endoscopic access post-gastric bypass, offering favorable outcomes.
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Coledocolitiasis , Derivación Gástrica , Obesidad Mórbida , Recurrencia , Procedimientos Quirúrgicos Robotizados , Humanos , Femenino , Coledocolitiasis/cirugía , Derivación Gástrica/métodos , Anciano , Obesidad Mórbida/cirugía , Obesidad Mórbida/complicaciones , Procedimientos Quirúrgicos Robotizados/métodos , Resultado del TratamientoRESUMEN
Introducción: El Íleo biliar (IB) es una obstrucción intestinal mecánica muy poco frecuente, del 1 al 4 % de todas las obstrucciones intestinales, y es más común en pacientes de edad avanzada. Se produce a través de una fístula bilioentérica en el intestino delgado, sobre todo en el íleon distal. Luego de tener un enfoque diagnóstico mediante imagenología, en su gran mayoría, se opta por el tratamiento quirúrgico para eliminar el o los cálculos impactados. El éxito de esta intervención depende en gran medida del tamaño del cálculo biliar, de la ubicación de la obstrucción intestinal y comorbilidades preexistentes. Caso clínico: Mujer de 78 años con cuadro clínico de obstrucción intestinal, emesis de contenido fecaloide y sintomática respiratoria; se evidenció una masa concéntrica a nivel de íleon distal y proceso neumónico concomitante por tomografía toracoabdominal. Se realizó laparotomía exploratoria con enterolitotomía, extracción de cálculo y anastomosis íleo-ileal y fue trasladada a la UCI en donde presentó falla ventilatoria y requerimiento de ventilación mecánica; se confirmó infección viral por SARS-CoV-2 mediante RT - PCR. Discusión: El IB es una obstrucción intestinal que ocurre con mayor frecuencia en pacientes de edad avanzada. Se habla de la fisiopatología y mecanismo de producción de la fístula entérica y se presentan opciones diagnósticas, terapéuticas y quirúrgicas para dirigir el manejo clínico más apropiado. Conclusión: El IB es difícil de diagnosticar. Debido a su baja incidencia, no existe un consenso que paute el manejo a seguir en los pacientes con diagnóstico de IB. Aunque el tratamiento estándar es la intervención quirúrgica, hay diversas opiniones en cuanto al tipo de cirugía a realizar.
Introduction: Biliary ileus (BI) is a very rare mechanical intestinal obstruction, responsible for 1-4% of all intestinal obstructions and more frequent in elderly patients. It occurs through a bilioenteric fistula in the small bowel, mainly in the distal ileum. After a diagnostic imaging approach, the vast majority opt for surgical treatment to remove the impacted stone or stones. The success of this intervention depends largely on the size of the stone, the location of the bowel obstruction and pre-existing comorbidities. Case report: 78-year-old woman with clinical symptoms of intestinal obstruction, fecaloid emesis, respiratory symptoms, concentric mass at the level of the distal ileum and concomitant pneumonic process in the thoraco-abdominal CT scan. Exploratory laparotomy was performed, with total lithotomy, extraction of the calculus and ileo-ileal anastomosis, and she was transferred to the ICU, where she presented ventilatory failure and required mechanical ventilation. SARS-CoV-2 infection was confirmed with RT-PCR. Discussion: IB is an intestinal obstruction that occurs more frequently in elderly patients. The pathophysiology and the mechanism of production of enteric fistula are discussed and diagnostic, therapeutic and surgical options are presented to guide the most appropriate clinical management. Conclusion: Enteric fistula is difficult to diagnose. Due to its low incidence, there is no consensus on the management of patients diagnosed with IB. Although the standard treatment is surgical intervention, there are divergent opinions as to the type of surgery to be performed.
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Humanos , Femenino , Anciano , Sistema Biliar , Enfermedades de las Vías Biliares , Cálculos Biliares , SARS-CoV-2 , Íleon , Neumonía , Fístula Biliar , Obstrucción Intestinal , LaparotomíaRESUMEN
SpyGlass DS es un sistema de colangioscopia peroral, asociado a mejor calidad de imagen y conFiguración. Actualmente, existe diversidad en su uso y escasa información sobre su implementación, incluyendo resultados clínicos y eventos adversos. Describir la experiencia de uso del SpyGlass DS en varios centros de referencia en gastroenterología en Colombia, mencionando eficacia y posibles eventos adversos. Este es un estudio observacional (serie de casos). La principal indicación fue coledocolitiasis (n:204), seguida de estenosis biliar (n:40) y pancreatolitiasis (n:16). 49,2% fueron hombres, edad media de 58,6 años, clínicamente con predominio de dolor abdominal (80,5%) e ictericia (86,1%). Todos los casos presentaron diagnóstico por imagen previo (tomografía computarizada, resonancia magnética o ecografía), 98,07% colangiopancreatografía retrógrada endoscópica previa (n:255) y 75% stent plástico biliar. Se utilizó láser en 78/220 pacientes y litotricia electrohidráulica en 142/220 pacientes, con tasas de resolución en una sola sesión 96,15% y 95,07%, respectivamente. Siete casos requirieron segunda sesión de litotricia y 3 pacientes requirieron manejo quirúrgico, uno por pancreatolitiasis con páncreas divisum de base y 2 por hepatolitiasis. 40/260 pacientes presentaron estenosis biliar, 32/40 con hallazgos malignos (colangiocarcinoma) y 8/40 con patología benigna (colangitis esclerosante primaria, cambios inflamatorios inespecíficos) tras estudios histopatológicos. Como complicaciones, se registraron 6 casos de bacteriemia (2,5%), siendo más frecuentes en casos de estenosis. La estancia media postoperatoria fue 2,04 días. Concluimos que el uso del SpyGlass DS es factible en nuestro medio, siendo eficaz para diagnóstico y tratamiento de lesiones biliares, y con bajo riesgo de eventos adversos.
SpyGlass DS is a peroral cholangioscopy system, associated with improved image quality and conFiguration. Currently, there is diversity in its use and little information on its implementation, including clinical outcomes and adverse events. To describe the experience of using SpyGlass DS in several gastroenterology reference centres in Colombia, mentioning efficacy and possible adverse events. This is an observational study (case series). The main indication was choledocholithiasis (n:204), followed by biliary stricture (n:40) and pancreatolithiasis (n:16). 49.2% were male, mean age 58.6 years, clinically with predominance of abdominal pain (80.5%) and jaundice (86.1%). All cases had previous imaging (CT scan, MRI or ultrasound), 98.07% previous endoscopic retrograde cholangiopancreatography (n:255) and 75% biliary plastic stent. Laser was used in 78/220 patients and electrohydraulic lithotripsy in 142/220 patients, with single-session resolution rates of 96.15% and 95.07%, respectively. Seven cases required a second lithotripsy session and 3 patients required surgical management, one for pancreatolithiasis with basal pancreas divisum and 2 for hepatolithiasis. 40/260 patients presented with biliary stricture, 32/40 with malignant findings (cholangiocarcinoma) and 8/40 with benign pathology (primary sclerosing cholangitis, non-specific inflammatory changes) after histopathological studies. As complications, 6 cases of bacteraemia (2.5%) were recorded, being more frequent in cases of stenosis. The mean postoperative stay was 2.04 days. We concluded that the use of SpyGlass DS is feasible in our setting, being effective for diagnosis and treatment of biliary lesions, and with low risk of adverse events.
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Congenital biliary tree malformations are rarely described in the veterinary field. A congenital umbilicobiliary fistula associated with gallbladder agenesis was reported here for the first time in a 1-year-old male French bulldog. After contrast study, abdominal ultrasound, and histopathology, we concluded that the umbilicobiliary fistula was an aberrant duct that originated directly from the expected location of the cystic duct and gallbladder. The clinical case was treated surgically through ligation and excision of the aberrant duct before entering the common bile duct. The recovery and long-term follow-up were uneventful. The pathophysiology of biliary congenital malformations is discussed, along with clinical considerations that should be considered in similar future cases.
As malformações congênitas da árvore biliar são raramente descritas na veterinária. Uma fístula umbilicobiliar congênita associada à agenesia da vesícula biliar foi relatada aqui pela primeira vez em um buldogue francês macho de 1 ano de idade. Após estudo contrastado, ultrassonografia abdominal e histopatologia, concluímos que a fístula umbilicobiliar era um ducto aberrante que se originava diretamente da localização esperada do ducto cístico e da vesícula biliar. O caso clínico foi tratado cirurgicamente através da ligadura e excisão do ducto aberrante antes de entrar no ducto colédoco. A recuperação e o acompanhamento a longo prazo transcorreram sem intercorrências. A fisiopatologia das malformações congênitas biliares é discutida, juntamente com considerações clínicas que devem ser consideradas em casos futuros semelhantes.
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RESUMEN Introducción: Las complicaciones relacionadas con la anastomosis biliar son reconocidas como la primera causa de morbilidad postrasplante hepático y pueden repercutir de manera negativa en la supervivencia de los pacientes. Objetivo: Evaluar el comportamiento de la supervivencia a largo plazo en los pacientes con complicaciones biliares postrasplante. Métodos: Se realizó un estudio observacional, longitudinal y retrospectivo en 152 pacientes con trasplante hepático entre 1999 y 2019. Se excluyeron: pacientes con supervivencia menor de 72 horas, retrasplantes y pacientes con trombosis de la arteria hepática. Las variables estudiadas fueron edad y sexo de los receptores, causa pretrasplante, escala Model for End Stage Liver Desease, usada a nivel mundial para determinar el estado de la enfermedad hepática y asignar órganos a los candidatos a trasplante, técnica de anastomosis biliar, tipo de complicación biliar, tiempo de aparición y terapéutica empleada. Las variables categóricas se relacionaron mediante la prueba estadística chi cuadrado y prueba exacta de Fisher, con diferencias significativas cuando p< 0,05; en el estudio de las variables cuantitativas se aplicó la prueba t - Student y para el análisis de la supervivencia se utilizaron curvas de Kaplan-Meier. Resultados: Se relacionaron de forma significativa con la presencia de complicación biliar, una puntuación mayor de la escala de valores de Model for End Stage Liver Desease (p=0,008) y la técnica de anastomosis término-terminal (p=0,039). Predominaron las complicaciones biliares precoces y la estenosis anastomótica. El tratamiento por colangiopancreatografía retrógrada endoscópica fue el más empleado. Los pacientes con complicación biliar tuvieron una media de supervivencia de 10,9 años (IC del 95 % 8,75-13,19), mientras que los pacientes sin ésta, tuvieron una media de nueve años (IC del 95 % 7,03-10,98); no existió diferencia significativa (p=0,24). Conclusiones: Las complicaciones biliares constituyeron una causa importante de morbilidad postrasplante, pero sin afectar la supervivencia de los pacientes.
ABSTRACT Introduction: Complications related to biliary anastomosis are recognized as the first cause of post-liver transplantation morbidity and can negatively affect patient survival. Objective: To evaluate the behavior of long-term survival in patients with post-transplant biliary complications. Methods: An observational, longitudinal, and retrospective study was carried out in 152 patients with liver transplantation between 1999-2019, the following were excluded: patients with survival less than 72 hours, retransplants and patients with hepatic artery thrombosis. The variables studied were age and sex of the recipients, pre-transplant etiology, MELD index (Model for End Stage Liver Desease), biliary anastomosis technique, type of biliary complication, time of onset and treatment used. The categorical variables were related using the Chi square statistical test and Fisher's exact test, with significant differences when p <0.05; In the study of quantitative variables, the T-Student test was applied and Kaplan - Meier curves were used for survival analysis. Results: They were significantly related to the presence of biliary complication, a higher MELD index score (p = 0.008) and the end-to-end anastomosis technique (p = 0.039). Early biliary complications (66.7%) and anastomotic stenosis (58.7%) predominated. Treatment by endoscopic retrograde cholangiopancreatography (ERCP) was the most used (68.2%). Patients with biliary complications had a mean survival of 10.9 years (95% CI 8.75-13.19), while patients without it had a mean of 9 years (95% CI 7.03 -10.98); there was no significant difference (p = 0.24). Conclusions: Biliary complications were an important cause of post-transplant morbidity, but without affecting patient survival.
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La colecistitis xantogranulomatosa (CXG) y la adenomiomatosis (AV) son infrecuentes, con escasos reportes en nuestro medio. La diferenciación preoperatoria e intraoperatoria es difícil, porque presenta características radiológicas y macroscópicas similares al cáncer. Frecuentemente se presenta como una colecistitis aguda. Y el diagnóstico se establece por la presencia de fibrosis, histiocitos espumosos, y de los senos de Rokitansky-Aschoff, respectivamente. Presentamos el caso de una mujer que acudió por dolor abdominal, náuseas y vómitos. La tomografía reveló una colección hepática subcapsular. Se interviene quirúrgicamente y se evidencia absceso hepático bloqueado por epiplón, con múltiples adherencias; y vesícula de paredes engrosadas perforada en bacinete. La paciente recibe antibioticoterapia, cursa con buena evolución, y la histopatología concluye una CXG y AV. La CXG y la AV son enfermedades raras, asociadas a colelitiasis. En nuestro caso, su asociación y su complicación con absceso hepático hacen que sea particularmente excepcional. Requiriendo ambas, cirugía e histopatología para confirmarlas.
Xanthogranulomatous cholecystitis (CXG) and Adenomyomatosis (VA) are rare, with few reports in our setting. The preoperative and intraoperative differentiation is difficult because it presents radiological and macroscopic characteristics, similar to cancer. It often presents as acute cholecystitis. And the diagnosis is established by the presence of fibrosis, foamy histiocytes, and Rokitansky-Aschoff sinuses, respectively. We present the case of a woman who came in for abdominal pain, nausea and vomiting. The tomography revealed a subcapsular liver collection. Surgery was performed and a hepatic abscess blocked by the omentum was evidenced, with multiple adhesions; and thickened-walled vesicle perforated in bacinete. Patient receives antibiotic therapy, progresses well, and histopathology concludes CXG and VA. CXG and VA are rare diseases associated with cholelithiasis. In our case, its association, and its complication with liver abscess, make it particularly exceptional. Requiring both surgery and histopathology to confirm them.
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OBJECTIVE: To investigate long-term results of biliary biopsy performed with transluminal forceps in the setting of metastatic biliary involvement. MATERIALS AND METHODS: Between September 2014 and June 2019, 25 patients-18 males (72%)-with a mean age of 65 ± 15 years, underwent 26 biliary biopsy procedures with a dedicated forceps system. All patients presented with obstructive jaundice that was suspected of being malignant and underwent pre-procedural magnetic resonance cholangiopancreatography. The biopsies were performed during percutaneous placement of an internal-external biliary drainage catheter, under fluoroscopic guidance. RESULTS: The technical success rate was 96% (corresponding to 25 of the 26 procedures). The histological diagnosis was inflammatory biliary stricture in five cases, pancreatic adenocarcinoma in six, liver metastases from colorectal cancer in eight, and hepatocellular carcinoma in three, the biliary mucosa being categorized as normal in three cases. In one case, the sample was considered insufficient and the procedure was successfully repeated, after which a diagnosis of pancreatic adenocarcinoma was made. Over a follow-up period of 6-48 months, there were five false-negative results: two findings of inflammatory biliary stricture were later identified as liver metastases from breast and gastric cancer, respectively; and all three patients in which the biliary mucosa was categorized as normal were subsequently diagnosed with metastatic hilar lymph nodes. The procedure was found to have a sensitivity of 77%, a specificity of 100%, and an overall accuracy of 80%. The complication rate was 11.5% (mild, transient hemobilia occurring in three cases). CONCLUSION: Percutaneous transluminal forceps biopsy is a safe, effective, minimally invasive procedure for histological characterization in patients presenting with obstructive jaundice due to a non-primary biliary tumor.
OBJETIVO: Investigar os resultados a longo prazo da biópsia endobiliar realizada com um pinça tipo fórceps transluminal no diagnóstico de neoplasia biliar metastática. MATERIAIS E MÉTODOS: Entre setembro de 2014 e junho de 2019, 25 pacientes - 18 homens (72%), com idade média de 65 ± 15 anos) - foram submetidos a 26 procedimentos de biópsia endobiliar com um conjunto dedicado. Todos os pacientes apresentaram icterícia obstrutiva, suspeita de malignidade e colangiorressonância pré-procedimento. Os procedimentos foram realizados durante o posicionamento percutâneo da drenagem biliar interna-externa, sob orientação fluoroscópica. RESULTADOS: A taxa de sucesso técnico foi de 96% (25 casos), com diagnóstico histológico de estenose benigna (inflamatória) em cinco casos, adenocarcinoma pancreático em seis casos, metástases hepáticas retais no cólon em oito casos, carcinoma hepatocelular em três casos e de mucosa biliar normal em três casos. Em um caso a amostra foi considerada insuficiente pelo patologista (um adenocarcinoma pancreático) e o procedimento foi repetido com sucesso. O seguimento de 6 a 48 meses mostrou cinco casos falso-negativos, em particular dois casos de metástases hepáticas retais sem cólon (câncer de mama e gástrico) e três linfonodos hilares metastáticos. A análise estatística revelou sensibilidade de 77%, especificidade de 100% e precisão geral de 80%. A taxa de complicações foi de 11,5% (três casos com hemobilia transitória). CONCLUSÃO: A biópsia biliar transluminal realizada com pinça tipo fórceps é um procedimento minimamente invasivo, seguro e eficaz para caracterização histológica em pacientes que apresentam icterícia obstrutiva no diagnóstico de neoplasia biliar metastática.
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Abstract Objective: To investigate long-term results of biliary biopsy performed with transluminal forceps in the setting of metastatic biliary involvement. Materials and Methods: Between September 2014 and June 2019, 25 patients-18 males (72%)-with a mean age of 65 ± 15 years, underwent 26 biliary biopsy procedures with a dedicated forceps system. All patients presented with obstructive jaundice that was suspected of being malignant and underwent pre-procedural magnetic resonance cholangiopancreatography. The biopsies were performed during percutaneous placement of an internal-external biliary drainage catheter, under fluoroscopic guidance. Results: The technical success rate was 96% (corresponding to 25 of the 26 procedures). The histological diagnosis was inflammatory biliary stricture in five cases, pancreatic adenocarcinoma in six, liver metastases from colorectal cancer in eight, and hepatocellular carcinoma in three, the biliary mucosa being categorized as normal in three cases. In one case, the sample was considered insufficient and the procedure was successfully repeated, after which a diagnosis of pancreatic adenocarcinoma was made. Over a follow-up period of 6-48 months, there were five false-negative results: two findings of inflammatory biliary stricture were later identified as liver metastases from breast and gastric cancer, respectively; and all three patients in which the biliary mucosa was categorized as normal were subsequently diagnosed with metastatic hilar lymph nodes. The procedure was found to have a sensitivity of 77%, a specificity of 100%, and an overall accuracy of 80%. The complication rate was 11.5% (mild, transient hemobilia occurring in three cases). Conclusion: Percutaneous transluminal forceps biopsy is a safe, effective, minimally invasive procedure for histological characterization in patients presenting with obstructive jaundice due to a non-primary biliary tumor.
Resumo Objetivo: Investigar os resultados a longo prazo da biópsia endobiliar realizada com um pinça tipo fórceps transluminal no diagnóstico de neoplasia biliar metastática. Materiais e Métodos: Entre setembro de 2014 e junho de 2019, 25 pacientes - 18 homens (72%), com idade média de 65 ± 15 anos) - foram submetidos a 26 procedimentos de biópsia endobiliar com um conjunto dedicado. Todos os pacientes apresentaram icterícia obstrutiva, suspeita de malignidade e colangiorressonância pré-procedimento. Os procedimentos foram realizados durante o posicionamento percutâneo da drenagem biliar interna-externa, sob orientação fluoroscópica. Resultados: A taxa de sucesso técnico foi de 96% (25 casos), com diagnóstico histológico de estenose benigna (inflamatória) em cinco casos, adenocarcinoma pancreático em seis casos, metástases hepáticas retais no cólon em oito casos, carcinoma hepatocelular em três casos e de mucosa biliar normal em três casos. Em um caso a amostra foi considerada insuficiente pelo patologista (um adenocarcinoma pancreático) e o procedimento foi repetido com sucesso. O seguimento de 6 a 48 meses mostrou cinco casos falso-negativos, em particular dois casos de metástases hepáticas retais sem cólon (câncer de mama e gástrico) e três linfonodos hilares metastáticos. A análise estatística revelou sensibilidade de 77%, especificidade de 100% e precisão geral de 80%. A taxa de complicações foi de 11,5% (três casos com hemobilia transitória). Conclusão: A biópsia biliar transluminal realizada com pinça tipo fórceps é um procedimento minimamente invasivo, seguro e eficaz para caracterização histológica em pacientes que apresentam icterícia obstrutiva no diagnóstico de neoplasia biliar metastática.
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Resumen La Ascariasis es la geohelminitiasis más común del mundo, catalogándose como una enfermedad tropical desatendida, que puede causar compromiso pulmonar, gastrointestinal, hepatobiliar y nutricional. Se presenta el caso inusual de una lactante procedente de una zona de extrema pobreza quien consultó por fiebre, vómito, ausencia de deposiciones, distensión y dolor abdominal. Fue diagnosticada con pseudoobstrucción intestinal, desnutrición severa, choque séptico de origen intraabdominal, retraso del neurodesarrollo y deprivación psicoafectiva, cuyas imágenes reportaron ascariasis hepatobiliar y granulomas hepáticos calcificados y abscedados, con infestación severa por Ascaris lumbricoides. Recibió manejo antibiótico y antiparasitario con recuperación exitosa. En nuestro medio, las infecciones por helmintos son causa frecuente de anemia, retraso cognitivo y del crecimiento en niños en edad escolar. Sin embargo, la infestación y complicaciones hepatobiliares como colangitis, colecistitis, pancreatitis, litiasis biliar y hepatitis abscedada son inusuales en menores de dos años. A través de este caso se pretende resaltar la presentación atípica de la enfermedad en lactantes e incitar al fortalecimiento de las intervenciones en salud pública. MÉD.UIS.2020;33(1):67-72.
Abstract Ascariasis is the most common geohelminitiasis in the world. It is categorized as an unattended tropical disease, which can cause pulmonary, gastrointestinal, hepatobiliary and nutritional compromise. We present the unusual case of an infant from an extreme poverty area presenting fever, vomiting, absence of bowel movements, bloating and abdominal pain. She was diagnosed with intestinal pseudoobstruction, severe malnutrition, abdominal septic shock, neurodevelopmental delay and emotional deprivation. The images reported hepatobiliary ascariasis and calcified and abscessed hepatic granulomas, with severe infestation by Ascaris lumbricoides and Trichuris trichiura. She was treated with antibiotics and antiparasitic agents with successful recovery. In our environment, helminth infections are a frequent cause of anemia, stunting and neurodevelopmental delay in school-age children. However, infestation and hepatobiliary complications such as cholangitis, cholecystitis, pancreatitis, biliary lithiasis and hepatic abscess are unusual in children under two years old. Through this case, it is intended to highlight the atypical presentation of this disease at the age of this patient and encourage the strengthening of public health interventions. MÉD.UIS.2020;33(1):67-72.
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Humanos , Femenino , Lactante , Ascariasis , Enfermedades de las Vías Biliares , Ascaris lumbricoides , Pobreza , Eosinofilia Pulmonar , Medicina Tropical , Trichuris , Seudoobstrucción Intestinal , Trastornos de la Nutrición del Niño , Anemia Ferropénica , Desnutrición , Hepatomegalia , Anemia , Absceso Hepático , AntiparasitariosRESUMEN
INTRODUCTION: Orthotopic liver transplantation anastomotic biliary strictures (OLT ABS) are managed with endoscopic biliary stent therapy but the recurrence rate is substantial. Our aims were to retrospectively determine the recurrence rates of OLT ABS after initial successful stent therapy, characterize the management of recurrences and identify associated variables. MATERIALS AND METHODS: Clinical data from 943 patients receiving non-living donor OLT at our institution from 2005-2012 were reviewed, and 123 OLT ABS patients receiving stent therapy were identified. Features of their endoscopic stent therapy and other pertinent clinical information were evaluated. RESULTS: ABS recurred in 25.5% of patients (24/94) after an initial successful course of stent therapy. Recurrences were received a second course of endoscopic stent therapy and 67% of patients (16/24) achieved long-term remediation of ABS. Six patients underwent a third course of endoscopic stent therapy with 4 patients achieving remediation. Overall remediation rate among ABS recurrences was 83.3% (20/24). A bivariate comparison demonstrated HCV infection, age, median months of maximal stenting and a lower maximum cumulative stent diameter were risk factors for ABS recurrence. Using a Cox regression model, only HCV status proved to be a risk factor for recurrence. DISCUSSION: In conclusion repeat stent therapy achieved high stricture remediation rates. Recurrence after the first or even second course of stenting should not imply failure of endoscopic therapy. A positive HCV status may be associated with higher stricture recurrence rates and this association should be further investigated.
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Colangiopancreatografia Retrógrada Endoscópica , Colestasis/cirugía , Trasplante de Hígado/efectos adversos , Adulto , Anciano , Colangiopancreatografia Retrógrada Endoscópica/efectos adversos , Colangiopancreatografia Retrógrada Endoscópica/instrumentación , Colestasis/diagnóstico por imagen , Colestasis/etiología , Constricción Patológica , Femenino , Hepatitis C/complicaciones , Humanos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Modelos de Riesgos Proporcionales , Recurrencia , Estudios Retrospectivos , Factores de Riesgo , Stents , Factores de Tiempo , Resultado del Tratamiento , Adulto JovenRESUMEN
The pancreatic biliary maljunction is a rare anomaly that affects mainly females, defined as an anatomical maljunction of the pancreatic duct and the biliary duct confluence, and may be a rare cause of recurrent acute pancreatitis. In order to early diagnosis and prompt treatment, ERCP has an important role in it
La Malformación de la unión biliopancreática es una afección rara y ocurre más en mujeres jóvenes. Es una causa de pancreatitis aguda de causa no conocida. CPRE es una herramienta eficiente para el diagnóstico y también para ser de la terapéutica
Asunto(s)
Adulto , Femenino , Humanos , Conductos Pancreáticos/anomalías , Pancreatitis/etiología , Conductos Biliares/anomalías , Colangiopancreatografia Retrógrada Endoscópica , Anomalías del Sistema Digestivo/diagnóstico por imagen , Conductos Pancreáticos/diagnóstico por imagen , Recurrencia , Conductos Biliares/diagnóstico por imagen , Anomalías del Sistema Digestivo/complicacionesRESUMEN
In HIV-infected patients, liver and biliary tract may be affected by different entities, such as AIDS-cholangiopathy, which is usually associated with CD4+T lymphocytes count below 100 cells/mm³ along with non-specific symptoms. Although imaging studies play a major diagnostic role they should always be evaluated according to patients clinical context. While ultrasound and CT scans provide relevant diagnostic information, specialized studies such as MRI and MRCP have become increasingly valuable due to their ability to demonstrate parietal as well as stenotic biliary changes. Despite ERCP remains the gold-standard for diagnosis of AIDS-related cholangiopathy, currently it is usually reserved to clearly exclude the presence of malignancy, or as a specific invasive therapeutic procedure, when indicated.
En pacientes infectados con VIH, el hígado y las vías biliares pueden presentar compromiso de distinta índole. Dentro de éstos, la colangiopatía asociada al SIDA se presenta con una sintomatología más bien inespecífica y habitualmente con recuentos de linfocitos T CD4 <100/mm³. En este escenario, si bien los estudios de imagen juegan un rol muy relevante, éstos siempre deben ser evaluados en relación al contexto clínico del paciente. Si bien la ecografía y la TC aportan valiosa información en el diagnóstico, en la actualidad la resonancia magnética de abdomen combinada con colangioresonancia tienen gran utilidad, por ser capaces de demostrar tanto las alteraciones parietales, como los cambios morfológicos estenóticos biliares de esta patología. Si bien la ERCP aún conserva su valor de gold standard para el diagnóstico, actualmente la tendencia se dirige a reservarla para el descarte de neoplasias, en casos dudosos o como procedimiento terapéutico invasivo específico, cuando sea indicado.
Asunto(s)
Adulto Joven , Colangitis Esclerosante/diagnóstico , Colangitis Esclerosante/etiología , Enfermedades de las Vías Biliares/diagnóstico , Enfermedades de las Vías Biliares/etiología , Síndrome de Inmunodeficiencia Adquirida/complicaciones , Imagen por Resonancia Magnética , Infecciones Oportunistas Relacionadas con el SIDA , Colangiopancreatografia Retrógrada EndoscópicaRESUMEN
Background: Bile duct injury (BDI) is a complex problem, where adequate reconstruction has an impact on quality of life of patients. Aim: To describe the experience and results of bile duct reconstruction in BDI at reference center. Material and Methods: Retrospective review of 25 patients aged 44 +/- 14 (76 percent females) with BDI that were subjected to a surgical repair in a regional hospital between January 2000 and June 2009. The protocol, repair technique and postoperative morbidity and mortality are described. Results: In 40 percent of cases, the injury occurred during laparoscopic cholecystectomy. The repair was performed using a Roux-en-Y hepato-jejunostomy (RYHJ) in 20 patients. In 14 patients (70 percent), the modified Hepp-Couinaud technique was used. Thirty two percent of patients had postoperative complications and one patient died due to a sepsis and liver failure. One patient presented RYHJ stenosis that was managed with percutaneous dilatation. Conclusions: The majority of patients of this series were managed using a RYHJ with the Hepp-Couinaud technique, with acceptable results in terms of postoperative morbidity and stenosis.
Introducción: La lesión de vía biliar (LVB) es una complicación de enfrentamiento complejo, donde una adecuada reconstrucción tiene impacto en la calidad de vida de los pacientes. Objetivo: Describir la experiencia y resultados de la reconstrucción de via biliar por LVB en un centro de referencia. Material y Método: Diseño de estudio: Cohorte retrospectiva. Período de estudio: Enero de 2000 a Junio de 2009. Población: Pacientes mayores de 18 años con LVB que fueron sometidas a reconstrucción de vía biliar por el equipo de cirugía hepatopancreática y biliar del Hospital Regional de Temuco. Maniobra: Se describe el protocolo de evaluación y la técnica de reconstrucción. Resultados: La cohorte está constituida por 25 pacientes. La edad promedio es 44 +/- 13,7 años y el 76 por ciento género femenino. La lesión se produjo más frecuentemente en una colecistectomía laparoscópica (40 por ciento). La reparación se ha realizado con hepaticoyeyuno anastomosis en Y de Roux (HPYA) en 20 pacientes, utilizando la técnica de Hepp-Couinaud modificada en el 70 por ciento de ellos. Ocho pacientes presentaron alguna morbilidad asociada a la reparación y un paciente falleció en el postoperatorio. Un paciente presentó estenosis de HPYA cuya terapia fue dilataciones por vía percutanea. Conclusión: La HPYA con técnica de Hepp-Couinaud es la técnica más utilizada por nuestro equipo en la reconstrucción de vía biliar por LVB con resultados aceptables en términos de morbilidad postoperatoria y estenosis.
Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Colecistectomía Laparoscópica/efectos adversos , Conducto Colédoco/cirugía , Conducto Colédoco/lesiones , Procedimientos Quirúrgicos del Sistema Biliar/métodos , Anastomosis en-Y de Roux , Estudios de Cohortes , Enfermedades del Conducto Colédoco/cirugía , Estudios de Seguimiento , Enfermedad Iatrogénica , Morbilidad , Procedimientos de Cirugía Plástica , Resultado del TratamientoRESUMEN
Endoscopic ultrasonography has become an important diagnostic and therapeutic tool in endoscopy units. It has a great impact on biliary and pancreatic disease management and its application to retrograde cholangiopancreatography is appealing, although very challenging with current devices. In this article we describe our initial experience with this technique.