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In order to study the relationship between China's safety production indicators and economic and social indicators, the development trend of indicator data in the past 20 years was statistically analyzed, and qualitative and quantitative research was conducted using grey relational analysis and multiple linear regression analysis methods. In the past two decades, there has been a significant improvement in the number of deaths, work-related injuries, and occupational patients in China's safety production, and the country's three categories of 14 economic and social indicators have achieved rapid development. Using the grey relation analysis method, the grey correlation degree between the number of deaths, work-related injuries, and occupational patients in China over the past twenty years and 14 economic and social indicators was obtained. The ranking of economic and social indicators that affect the number of deaths, work-related injuries, and occupational patients varies greatly. A multiple linear regression model was established for the number of deaths, work-related injuries, occupational diseases, and 14 economic and social indicators. The rationality of the model was verified from four aspects: R2, F-value, P-value, and deviation between actual and fitted values. Provide guidance for the development of safety production indicators and economic and social indicators in China through research.

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Biochar, as a soil amendment, can be applied to remediate heavy metal (HM) contaminated farmland. However, there is little research on the effect of tobacco biochar (TB) derived from tobacco waste on HM controlling in edible parts of vegetables. In this study, the impact of two TB levels on the plant growth, copper (Cu) and cadmium (Cd) accumulation in the edible parts of lettuce and chrysanthemum, and on Cu and Cd bioavailability of rhizosphere soil was investigated through in-situ field experiments. The results showed that TB has rich oxygen containing functional groups, high porosity, high nitrogen adsorption capacity. The addition of 5 t ha-1 and 10 t ha-1 TB significantly increased the shoot biomass of chrysanthemum, but had no effect on the growth of lettuce. Two levels of TB significantly increased the pH value, but decreased the available Cu and Cd concentrations of rhizosphere soil, thereby reducing the Cu and Cd accumulations in the edible parts of lettuce and chrysanthemum. The findings provided effective evidences that TB derived from tobacco waste is an efficient strategy for controlling Cu and Cd accumulation in the edible parts of vegetables to ensure agri-product safety production in HM-polluted farmland.

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"How to realize farmers to actively produce quality and safety agricultural products" has become a common problem faced by researchers and practitioners. Based on the Triadic Reciprocal Determinism theory and Behavior-motivation theory, the study tries to answer this question from the perspective of standardized farmer professional cooperatives in China, and then solve relevant international problems. The empirical results of 767 sample data using SPSS-AMOS methods show that the restraint factors of standardized farmer professional cooperative have positive effects on safety negative behavior and negative impact on safety positive behavior, and the motivation factors of standardized farmer professional cooperatives have positive effects on safety positive behavior. The restraint factors of farmer professional cooperatives have a positive impact on safety controlled motivation and negative impact on safety autonomous motivation, and the motivation factors of farmer professional cooperatives positively affect the safety autonomous motivation. The safety controlled motivation positively affects safety negative behavior and safety autonomous motivation negatively affects safety negative behavior and positively impacts on safety positive behavior. The above findings theoretically make a useful supplement to the study of farmers' safety production behavior, and have guiding significance to the construction of standardized farmer professional cooperatives in the world.

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Cadmium (Cd) accumulation in rice has become a serious public concern; thus, it is important to find an effective approach to reducing Cd accumulation in rice grains to ensure food safety. To investigate the effects of different amendments on Cd accumulation in rice in Cd-contaminated farmland under different flooding treatments, a field experiment with three amendments (jade powder, biochar, and fly ash) and two flooding treatments (intermittent flooding and flooding throughout the whole growth period) was conducted. The results showed that:① without amendment application, the soil pH significantly increased, whereas the soil available Cd concentration decreased by 3.81%-17.27% and 2.25%-6.74% with the treatments of flooding throughout the whole growth period and intermittent flooding, respectively. Additionally, the immobilizing efficiency of the treatment of flooding throughout the whole growth period was better than that of intermittent flooding; ② under different flooding treatments, amendment application improved soil pH, resulting in a decrease in the soil available Cd concentration along with an increase in the residual Cd concentration. Under the treatment of intermittent flooding, the soil pH increased by 0.19-2.20 units, and the soil available Cd concentration and Cd concentration in rice grains decreased by 4.72%-22.68% and 2.60%-75.75%, respectively, with the application of different amendments. Under the treatment of flooding throughout the whole growth period, the application of different amendments decreased the soil available Cd concentration and Cd concentration in rice grains by 5.06%-36.63% and 13.28%-77.01%, respectively. The immobilizing efficiency in both flooding treatments was jade powder > biochar > fly ash. ③ Under different flooding treatments, the application of amendments significantly reduced the soil available Cd concentration and Cd concentration in rice grains. Among the three amendments, jade powder showed the best capacity of immobilizing efficiency with the treatment of flooding throughout the whole growth period; the soil Cd reduction rates were 36.63% and 25.16%, and the Cd concentrations in rice grains were 0.058 and 0.170 mg·kg-1 in 2019 and 2020, respectively. The Cd concentrations in rice grains were within the limitation of the National Food Hygienic Standard of China. Therefore, combining flooding throughout the whole growth period with jade powder can be considered as an ideal strategy for ensuring rice safety in Cd-contaminated farmland.

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Phytoremediation potential of two oil crop rotations (oilseed sunflower-rape (O+Ra) and peanut-oilseed rape (P+Ra)) was compared with three conventional cropping patterns (rice-rape (R+Ra), rice-rice (R+R), single cropped rice (SR)) in experimental plots with cadmium (Cd)-contaminated soil. A new approach was used to evaluate phytoremediation potential based on the balance between annual input and output fluxes of Cd in farmland soil. In O+Ra and P+Ra rotations, 77.24 and 62.09 g/ha Cd were removed, respectively, whereas in R+Ra, R+R, and SR patterns, 41.79, 46.46, and 23.85 g/ha Cd were removed, respectively. The balance between inputs and outputs of Cd was - 40.72 and - 25.76 g/ha under O+Ra and P+Ra rotations, respectively. Available Cd content in topsoil was reduced by 5.58% and 3.91% under O+Ra and P+Ra rotations, respectively. Based on the balance between Cd inputs and outputs, phytoremediation efficiencies of O+Ra (1.23%) and P+Ra (0.78%) rotations were higher than those of R+R (0.29%), R+Ra (0.13%), and SR (-0.38%) systems. Because crop removal is the main Cd output pathway, selection of a suitable crop is particularly important in remediation of Cd-contaminated farmland.

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The evaluation index system of non-rigid demand service quality in safety production delineates the production safety-related services that are procured by enterprises from service organizations and are not mandatory by the state. Construction of the evaluation index system of non-rigid demand service quality in safety production is an effective way to improve the quality of the demand service. Based on the INDSERV model and on-site interviews, this study constructs a whole-process safety production non-rigid demand service quality evaluation model, clarifies the evaluation indicators and conducts on-site investigations to verify the effectiveness of the model, and further analyzes the data to determine each evaluation index weight. A safety production non-rigid demand service quality evaluation index and evaluation scale were constructed. Effective exploration was performed on the evaluation index system of non-rigid demand service quality in safety production, which provides a guarantee for promoting the development of the non-rigid demand service market.

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Cadmium (Cd) exposure is related to a multitude of adverse health outcomes because food crops grown on Cd-polluted soil are widely consumed by the public. The present study investigates the different application techniques of a combined amendment (lime + zeolite + biochar + compost, LZBC) for soil Cd immobilization effect on growth performance, Cd uptake by the second season crops, and soil quality in greenhouse vegetable production (GVP) under a rotation system. Five fruit vegetables were cultivated as the second season crop in the same plots which have been used for pakchoi as the first season crop (with or without LZBC application). The results indicated that LZBC with the consecutive application (T3) promoted crops biomass and fruit yield the most, followed by LZBC with the second crop application (T2) and LZBC with the first crop application (T1). LZBC application showed increasing rhizosphere soil pH and improvement in soil fertility of all crops including available nitrogen, available phosphorus, available potassium, organic matter, and cation exchange capacity. LZBC had positive influences on soluble sugar, soluble protein, and vitamin C in edible parts of 5 vegetables. Cd contents in fruit, shoot, and root of eggplant, pimento, cowpea, and tomato except cucumber were reduced by adding LZBC. As for the economic performance, T3 had the highest output/input ratio in general. Overall, these results demonstrated that T3 was dramatically more effective for minimizing health risk, increasing production, and facilitating sustainable utilization of soil under the Cd-contaminated GVP system.

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Phytoremediation coupled with co-cropping is assumed to be good for safety utilization and remediation of heavy metal contaminated farmland, which can ensure farmers' income without increasing health risks for human. In this study, the effects on plant cadmium (Cd) accumulation and health risk of consuming the vegetable plant were compared between monoculture and co-cropping of cauliflower (Brassica oleracea) with two ecotypes of Sedum alfredii in a moderately (0.82 mg kg-1) Cd contaminated greenhouse vegetable field. The results showed that co-cropping with S. alfredii raised Cd concentration in edible part of cauliflower with slightly growth promotion. The health risk of consuming cauliflower to different groups of people have been evaluated by calculating Hazard Quotient (HQ) and all HQ value were less than 1.0, which indicated that eating co-cropped cauliflower would not cause health risks to adults and children. Besides, the Cd concentration of hyperaccumulating ecotype (HE) of S. alfredii was 27.3 mg kg-1 in monoculture and it increased to 51.2 mg kg-1 after co-cropping with cauliflower, suggesting that the co-cropping system promoted HE Cd absorption capacity. Therefore, the "Phytoextraction Coupled with Agro-safe-production" (PCA) model of cauliflower and HE can serve as an alternative sustainable strategy in the Cd moderate polluted greenhouse.

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ABSTRACT Cosmetics have been used since the very first days of human life. This early and continuing consumption has resulted in the growth of the Cosmetic Industry (C.I.). The C.I. must continue to invest in the development of innovative products which are safe for the consumers. On the other hand, the Health Agency should issue laws regulating the development of products. Thus, the aim of this study was to evaluate the Brazilian Cosmetic Legislation before ANVISA and the challenges for the C.I. during the 20th century regarding the development of safe and effective cosmetics, and to show the importance of this legislation in the R&D. A Bibliographic and Documentary Exploratory Research was conducted based on safety and efficacy data contained in scientific studies and legal documents. The study showed that the creation of ANVISA was necessary because no resolution had been published about the safety and efficacy of cosmetics for the C.I. before ANVISA. However, the challenges faced by the C.I. may have had a negative impact on the health of consumers. Finally, it was concluded that the actions before ANVISA were insufficient to the C.I.. Thus, the creation of ANVISA was essential to have a regulatory basis fot the C.I.

RESUMO Os cosméticos são usados desde os primeiros dias de vida do ser humano. Consequentemente, esse consumo resulta no crescimento da Indústria Cosmética (I.C.). Com isso, a I.C. deve focar seus investimentos também no desenvolvimento de produtos inovadores, mas, acima de tudo, seguros para os consumidores. Por outro lado, a Agência Sanitária deve emitir leis que regulam o desenvolvimento desses produtos. Assim, o objetivo deste estudo foi avaliar a Legislação Cosmética Brasileira anterior à ANVISA e os desafios da I.C. no século XX no desenvolvimento de produtos cosméticos seguros e eficazes, bem como mostrar a importância dessa legislação na P&D. Para tal, realizou-se uma Pesquisa Exploratória Bibliográfica e Documental com base em estudos científicos e documentos legais. Dessa forma, o estudo mostrou que a criação da ANVISA foi necessária porque nenhuma resolução tinha sido publicada sobre a segurança e eficácia de cosméticos antes da ANVISA. Com isso, os desafios enfrentados pela I.C. poderiam ter um impacto negativo sobre a saúde dos consumidores. Por fim, concluiu-se que as ações anteriores à ANVISA foram insuficientes para a I.C. Assim, a criação da ANVISA foi essencial para ter uma base regulatória para a I.C..

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