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Objectives: Big data-based multicenter medical research is expected to bring significant advances to cancer treatment worldwide. However, there are concerns related to data sharing among multicenter networks. Clinical data can be shielded by firewalls using distributed research networks (DRNs). We attempted to develop DRNs for multicenter research that can be easily installed and used by any institution. Patients and Methods: We propose a DRN for multicenter cancer research called the cancer research line (CAREL) and present a data catalog based on a common data model (CDM). CAREL was validated using 1723 patients with prostate cancer and 14 990 patients with lung cancer in a retrospective study. We used the attribute-value pairs and array data type JavaScript object notation (JSON) format to interface third-party security solutions such as blockchain. Results: We developed visualized data catalogs of prostate and lung cancer based on the observational medical outcomes partnership (OMOP) CDM, from which researchers can easily browse and select relevant data. We made the CAREL source code readily available for download and application for relevant purposes. In addition, it is possible to realize a multicenter research network using CAREL development sources. Conclusion: CAREL source can enable medical institutions to participate in multicenter cancer research. Our technology is open source, so small institutions that cannot afford to spend high costs can use it to develop a platform for multicenter research.

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Investigar grupos de pesquisa (GPs) possibilita visualizar como está o desenvolvimento científico de uma área do conhecimento. Este estudo objetivou descrever a trajetória dos GPs da educação física no Brasil, caracterizando sua distribuição geográfica e vinculação nas linhas de pesquisa Escola, Saúde e Esporte. Foi realizada busca parametrizada no painel Lattes do Diretório de GPs. Desde 1993 houve crescimento no número de GP. Houve maior concentração nas regiões sudeste (n=250), sul (n=181) e nos estados de São Paulo (n=126) e Paraná (n=72). Alocou-se maior número de GPs na temática Esporte (n=247), seguido da Escola (n=122) e Saúde (n=113). Incentiva-se a nucleação de GPs nas regiões com menor número, de modo a promover o desenvolvimento científico em todo o país (AU).

o investigate research groups (RG) enable to visualize how is going the scientific development of a knowledge area. The aim of this study was to analyze the trajectory of physical education RG in Brazil, and characterize its geography distribution, and its distribution by research line (school, health and sports). A parameterized search at the DGOB Lattes was made. Since 1993 increase the number of RG. Higher concentration were found in southeast (n=250), South (n=181) and in São Paulo (n=126) and Paraná (72) state. Higher number of RG were found in Sport (n=247), follow by school (n=122) and health (n=113). Incentive is needed to increase the RG number in regions with lower numbers with the aim to develop the science in all country (AU).

Investigar grupos de investigación (GI) permite visualizar el desarrollo científico de un área de conocimiento. O el propósito de la investigación fue analizar la trayectoria de los GI de educación física en Brasil, caracterizando su distribución geográfica y lo vínculo con las líneas de investigación Escuela, Salud y Deporte. Se realizó una búsqueda paramétrica en el DGPB Lattes. Desde 1993, aumentado el número de GI. Mayor número en las regiones Sureste (n=250) y Sur (n=181) en los estados de São Paulo (n=126) y Paraná (72). Mayor número en los temas deporte (n=247), Escuela (n=122) y Salud (n=113). Se fomenta el aumento de GP en las regiones con menor número para promover el desarrollo científico en todo el país (AU).

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Investigar grupos de pesquisa (GPs) possibilita visualizar como está o desenvolvimento científico de uma área do conhecimento. Este estudo objetivou descrever a trajetória dos GPs da educação física no Brasil, caracterizando sua distribuição geográfica e vinculação nas linhas de pesquisa Escola, Saúde e Esporte. Foi realizada busca parametrizada no painel Lattes do Diretório de GPs. Desde 1993 houve crescimento no número de GP. Houve maior concentração nas regiões sudeste (n=250), sul (n=181) e nos estados de São Paulo (n=126) e Paraná (n=72). Alocou-se maior número de GPs na temática Esporte (n=247), seguido da Escola (n=122) e Saúde (n=113). Incentiva-se a nucleação de GPs nas regiões com menor número, de modo a promover o desenvolvimento científico em todo o país.

To investigate research groups (RG) enable to visualize how is going the scientific development of a knowledge area. The aim of this study was to analyze the trajectory of physical education RG in Brazil, and characterize its geography distribution, and its distribution by research line (school, health and sports). A parameterized search at the DGOB Lattes was made. Since 1993 increase the number of RG. Higher concentration were found in southeast (n=250), South (n=181) and in São Paulo (n=126) and Paraná (72) state. Higher number of RG were found in Sport (n=247), follow by school (n=122) and health (n=113). Incentive is needed to increase the RG number in regions with lower numbers with the aim to develop the science in all country.

Investigar grupos de investigación (GI) permite visualizar el desarrollo científico de un área de conocimiento. O el propósito de la investigación fue analizar la trayectoria de los GI de educación física en Brasil, caracterizando su distribución geográfica y lo vínculo con las líneas de investigación Escuela, Salud y Deporte. Se realizó una búsqueda paramétrica en el DGPB Lattes. Desde 1993, aumentado el número de GI. Mayor número en las regiones Sureste (n=250) y Sur (n=181) en los estados de São Paulo (n=126) y Paraná (72). Mayor número en los temas deporte (n=247), Escuela (n=122) y Salud (n=113). Se fomenta el aumento de GP en las regiones con menor número para promover el desarrollo científico en todo el país.

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Most epidemiologic studies fail to capture the impact of spatiotemporal fluctuations in traffic on exposure to traffic-related air pollutants in the near-road population. Using a case-crossover design and the Research LINE source (R-LINE) dispersion model with spatiotemporally resolved highway traffic data, we quantified associations between primary pollutants generated by highway traffic-particulate matter with an aerodynamic diameter less than or equal to 2.5 µm (PM2.5), oxides of nitrogen (NOx), and black carbon (BC)-and daily nonaccidental, respiratory, cardiovascular, and cerebrovascular mortality among persons who had resided within 1 km (0.6 mile) of major highways in the Puget Sound area of Washington State between 2009 and 2013. We estimated these associations using conditional logistic regression, adjusting for time-varying covariates. Although highly resolved modeled concentrations of PM2.5, NOx, and BC from highway traffic in the hours before death were used, we found no evidence of an association between mortality and the preceding 24-hour average PM2.5 exposure (odds ratio = 0.99, 95% confidence interval: 0.96, 1.02) or exposure during shorter averaging periods. This work did not support the hypothesis that mortality risk was meaningfully higher with greater exposures to PM2.5, NOx, and BC from highways in near-road populations, though we did incorporate a novel approach to estimate exposure to traffic-generated air pollution based on detailed traffic congestion data.

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OBJECTIVES: The Brazilian scientific production in the pediatrics field has been increasing significantly. It is important to identify the distribution and activity of these groups in the country and the main study areas, contributing with data for better resource allocation by institutions. METHODS: An active research was conducted in the National Council of Technological and Scientific Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico [CNPq]) website, using as filters the macro area of the research group (Health Sciences), the area (Medicine), and descriptors related to pediatrics. Research lines and main area of pediatric research groups were classified according to the subject predominantly studied by each group. The scientific production of the leader of the pediatric research group between 2011 and 2014 was also analyzed. RESULTS: Most pediatric research groups in Brazil have more than five years of activity and are concentrated in the Southeast and South regions of the country; São Paulo, Rio Grande do Sul, and Minas Gerais are the states with most groups. Of the 132 specific pediatric research groups analyzed, 14.4% have lines of research in multiple areas and 11.4% in child and adolescent health. Among the 585 lines of research of these groups, the most prevalent areas were: oncology, infectious diseases, epidemiology, and gastroenterology. CONCLUSIONS: The pediatric research groups in Brazil have relevant scientific production, including works published in international publications, and are concentrated in regions with higher socioeconomic index. Most groups registered in CNPq started their activity in the last five years (46%), reflecting the recent growth of scientific production in this area. .

OBJETIVOS: A produção científica brasileira na área da pediatria vem aumentando significativamente. Diante desse quadro, é importante identificar a distribuição e atividade desses grupos no país e as principais áreas estudadas para contribuir com dados para que as instituições possam alocar melhor seus recursos. MÉTODOS: Foi feita pesquisa ativa no site do Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), que teve como filtros a grande área do grupo - ciências da saúde - e área medicina e descritores relacionados à pediatria. Posteriormente foram classificadas as linhas de pesquisa e a área de atuação principal dos grupos de acordo com os temas prevalentemente estudados. Avaliou-se também a produção científica entre 2011 e 2014 dos coordenadores dos grupos de pesquisa pediátrica pelo currículo Lattes. RESULTADOS: A maioria dos grupos de pesquisa pediátrica do Brasil tem mais de cinco anos de atividade e está concentrada nas regiões Sudeste e Sul. São Paulo, Rio Grande do Sul e Minas Gerais, são os principais estados. Dos 132 grupos específicos de pesquisa pediátrica cadastrados, 14,4% têm linhas de pesquisa em múltiplas áreas e 11,4% em saúde da criança e do adolescente. Entre as 585 linhas de pesquisa desses grupos, são predominantes as áreas: oncologia, infectologia, epidemiologia e gastroenterologia. CONCLUSÕES: Os grupos de pesquisa pediátrica do Brasil têm produção relevante, até mesmo internacional, e estão concentrados nas regiões de maior índice socioeconômico. Grande parte dos grupos cadastrados no CNPq entrou em atividade nos últimos cinco anos (46%), o que evidencia crescimento recente da produção científica nessa área. .

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OBJECTIVES: The Brazilian scientific production in the pediatrics field has been increasing significantly. It is important to identify the distribution and activity of these groups in the country and the main study areas, contributing with data for better resource allocation by institutions. METHODS: An active research was conducted in the National Council of Technological and Scientific Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico [CNPq]) website, using as filters the macro area of the research group (Health Sciences), the area (Medicine), and descriptors related to pediatrics. Research lines and main area of pediatric research groups were classified according to the subject predominantly studied by each group. The scientific production of the leader of the pediatric research group between 2011 and 2014 was also analyzed. RESULTS: Most pediatric research groups in Brazil have more than five years of activity and are concentrated in the Southeast and South regions of the country; São Paulo, Rio Grande do Sul, and Minas Gerais are the states with most groups. Of the 132 specific pediatric research groups analyzed, 14.4% have lines of research in multiple areas and 11.4% in child and adolescent health. Among the 585 lines of research of these groups, the most prevalent areas were: oncology, infectious diseases, epidemiology, and gastroenterology. CONCLUSIONS: The pediatric research groups in Brazil have relevant scientific production, including works published in international publications, and are concentrated in regions with higher socioeconomic index. Most groups registered in CNPq started their activity in the last five years (46%), reflecting the recent growth of scientific production in this area.

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