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1.
Animal ; 18(9): 101262, 2024 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-39121722

RESUMEN

Intrauterine growth restriction (IUGR) is defined as inadequate foetal growth during gestation. In response to placenta insufficiency, IUGR piglets prioritise brain development as a survival mechanism. This adaptation leads to a higher brain-to-liver weight ratio (BrW/LW) at birth. This study assessed the potential of using morphometric traits to estimate brain (BrW) and liver (LW) weights, enabling non-invasive diagnosis of IUGR in newborn piglets. At birth, body weight (BtW) of individual piglets (n = 144) was recorded. One day (± 1) after birth, BrW and LW were measured with computed tomography (n = 94) or by weighing the organs after natural death or euthanasia (n = 50). Additionally, 20 morphometric traits were captured from images of each piglet and correlated with the BrW and LW. The morphometric traits that showed a r ≥ 0.70 in linear correlation with the BrW or LW were selected. Each selected trait was combined as an independent variable with BtW to develop multiple linear regression models to predict the BrW and LW. Six models were chosen based on the highest adjusted R2 value: three for estimating BrW and three for LW. The dataset was then randomly divided into a training (75% of the data) and a testing (remaining 25%) subsets. Within the training subset, three equations to predict the BrW and three to predict the LW were extrapolated from the six selected models. The equations were then applied to the testing subset. The accuracy of the equations in predicting organ weight was assessed by calculating mean absolute and mean absolute percentage error (MAE and MAPE) between predicted and actual BrW and LW. To predict the BrW/LW, an equation including BtW and the two morphometric traits which better predicted BrW and LW was used. In the testing dataset, the equation combining ear distance and BtW better estimated the BrW. The equation performed with a MAE of 1.95 and a MAPE of 0.06 between the true and estimated weight of the brain. For the liver, the equation combining the abdominal area delimited by a square and BtW displayed the best performance, with a MAE of 9.29 and a MAPE of 0.17 between the true and estimated weight. Finally, the MAE and MAPE between the actual and estimated BrW/LW were 0.14 and 0.17, respectively. These findings suggest that specific morphometric traits can be used to estimate brain and liver weights, facilitating accurate and non-invasive identification of IUGR in newborn piglets.


Asunto(s)
Animales Recién Nacidos , Encéfalo , Retardo del Crecimiento Fetal , Hígado , Animales , Retardo del Crecimiento Fetal/veterinaria , Retardo del Crecimiento Fetal/diagnóstico , Hígado/diagnóstico por imagen , Hígado/anatomía & histología , Tamaño de los Órganos , Femenino , Encéfalo/diagnóstico por imagen , Porcinos , Embarazo , Enfermedades de los Porcinos/patología , Enfermedades de los Porcinos/diagnóstico , Enfermedades de los Porcinos/diagnóstico por imagen , Peso Corporal
2.
Heliyon ; 9(11): e21730, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-38027752

RESUMEN

Several experiments of Fe3O4-SiO2/water hybrid nanofluids with volumetric concentrations ranging from 0.2 % to 1.0 % circulating in the cold-side of a plate heat exchanger at flow rates ranging from 0.05 kg/s to 0.1166 kg/s are performed. Under these ranges of flow rates and volumetric concentrations, the flow of Fe3O4-SiO2/water hybrid nanofluids remains laminar. The results of these experiments are predicted with support vector machine (SVM) algorithm to determine hybrid nanofluid entropy generation thermal, entropy generation frictional, and efficiency of exergy. Fe3O4-SiO2 nanomaterials was synthesized with reduction of chemicals and insitu development techniques, with XRD, FTIR and VSM instruments, characterizations were done. The SVM model gives large precision predictions of the measured data with correlations coefficients of 0.9944, 0.99798, and 0.99428 for frictional entropy generation, thermal entropy generation and exergy efficiency. At a flow rate of 0.1166 kg/s in the cold-side of PHE, the exergy efficiency is found to be 77.96 % for water (Reynolds number of 935.4) and with 1.0 vol% of Fe3O4-SiO2/water hybrid nanofluid in the cold-side of PHE, the efficiency is increased to 82.97 %, respectively. Under similar conditions of 0.1166 kg/s of flow circulation and 1.0 % vol. concentration of hybrid nanofluid, the thermal entropy generation is dropped off to 18.37 %, but the frictional entropy generation is increased by 20.97 %, compared to water, with the results that the total entropy generation drops off by 15.91 %, compared to water data. Preliminary curve-fitting correlations have been developed for the frictional entropy generation, thermal entropy generation, and exergy efficiency.

3.
Int Biomech ; 10(1): 18-28, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38014806

RESUMEN

There is a lack of knowledge in the literature concerning Body Segment Inertial Parameters (BSIP) for children aged 4 to 15 years. Nevertheless, these data are fundamental for studying the dynamics of the healthy and pathological musculoskeletal system. One common method for obtaining BSIP is to use regression equations derived from anthropometric tables. However, the majority of these equations are based on adult data. In this study, we compared certain BSIP (segment mass, center of mass position, and transverse moment of inertia) derived from adult anthropometric tables with the corresponding BSIP extracted from a pediatric anthropometric table. The goal of this study was to determine the accuracy of using adult anthropometric tables to calculate pediatric BSIP. For this comparison, we assessed the proximity of several adult anthropometric tables to a pediatric anthropometric table by Jensen (1986) for each BSIP. Our results revealed differences between the BSIP obtained using adult tables and the BSIP obtained with the pediatric table used as a reference. When considering all the tables, the mean relative difference was 12% for segment mass, 12% for center of mass position, and 25% for transverse moment of inertia. Notably, the greatest relative differences were observed for the head, hand, and foot segments. Additionally, the relative difference in female data was higher compared to males. This result could be attributed to the predominant use of male subjects in the adult tables considered in this study. Finally, the adult anthropometric tables by Dumas and Wojtsuch (2018) and De Leva (1996) provided results that were closer in comparison to Jensen (1986).


Asunto(s)
Extremidad Inferior , Movimiento , Humanos , Masculino , Adulto , Niño , Femenino , Fenómenos Biomecánicos , Antropometría , Pie
4.
Artículo en Inglés | MEDLINE | ID: mdl-37837205

RESUMEN

Childbirth is a complex physiological process in which a foetal neuromusculoskeletal model is of great importance to develop realistic delivery simulations and associated complication analyses. However, the estimation of hip joint centre (HJC) in foetuses remains a challenging issue. Thus, this paper aims to propose and evaluate a new approach to locate the HJC in foetuses. Hip CT-scans from 25 children (F = 11, age = 5.5 ± 2.6 years, height = 117 ± 21 cm, mass = 26 kg ± 9.5 kg) were used to propose and evaluate the novel acetabulum sphere fitting process to locate the HJC. This new approach using the acetabulum surface was applied to a population of 57 post-mortem foetal CT scans to locate the HJC as well as to determine associated regression equations using multiple linear regression. As results, the average distance between the HJC located using acetabulum sphere fitting and femoral head sphere fitting in children was 1.5 ± 0.7 mm. The average prediction error using our developed foetal HJC regression equations was 3.0 ± 1.5 mm, even though the equation for the x coordinate had a poor value of R2 (R2 for the x coordinate = 0.488). The present study suggests that the use of the acetabulum sphere fitting approach is a valid and accurate method to locate the HJC in children, and then can be extrapolated to get an estimation of the HJC in foetuses with incomplete bone ossification. Therefore, the present paper can be used as a guideline for foetus specific neuromusculoskeletal modelling.

5.
Heliyon ; 9(4): e15181, 2023 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-37113775

RESUMEN

The important process of aerosol dusting is of economic, environmental and heath significance. The objective was to investigate the climatic parameters including rainfall (R), wind speed (WS), temperature (T), and relative humidity (RH), as well as soil mineralogical and chemical properties affecting dust deposition rate (DDR), in a unique and rarely studied area, the Kuhdasht watershed (456 km2) of Lorestan province, Iran. Data were collected seasonally using glass-traps inserted in ten research stations to indicate DDR seasonal and spatial variations using ARC-GIS. The spatial distribution of organic matter (OM), clay and CaCO3, and the mineralogical properties (using diffractograms obtained by XRD) of the dust and soil samples were determined. The city had the highest DDR decreasing toward the mountains. Spring (3.28-4.18 ton/km2) and autumn (1.82-2.52 ton/km2) resulted in the highest and the least DDR, respectively. The diffractograms indicated the sources of dust were local or from out of the borders. The clay minerals (kaolinite and illite) and the evaporating minerlas (gypsum, calcite, dolomite, and halite), detected in the soil and dust samples indicated their contribution to the process of DDR. According to the regression models and the correlation coefficients, DDR was highly and significantly correlated with R (R2= 0.691), WS (0.685) and RH (0.463) indicating such parameters can importantly affect DDR in the semi-arid areas.

6.
Iran J Public Health ; 52(12): 2663-2672, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38435782

RESUMEN

Background: Cardio-respiratory fitness (CRF) is a strong predictor of overall health and is considered a key physiological measure in health care settings. Maximal oxygen uptake (VO2max) is considered the gold standard for measuring CRF. Non-exercise VO2max regression equations provide a safe, simple and relatively accurate means of measuring CRF in the general population. This study aimed to develop first native regression equations to predict of CRF without exercise test in Iranian healthy boys. Methods: Laboratory gold standard CRF and anthropometric variables were measured in 597 healthy boys (8-17 yr) in Hmadan City, Iran in 2019. Multiple regression analysis was used to generate CRF regression equations. Cross validation of the CRF regression equations was assessed using PRESS statistics, Pearson correlation, Bland-Althman plot and paired t-test. Results: CRF regression equations based on age, body mass index, body fat and resting heart rate were developed (R2=0.602 - 0.639, SEE = 3.42 - 3.73 ml/kg/min). PRESS statistics show that, shrinkage of the R2 (0.04 - 0.06) and the increment of SEE (0.18 - 0.25 ml/kg/min) is minor. There was strong correlation (R =0.847-0.883, P<0.001) and no significant difference (min diff= 0.09-0.18 ml/kg/min, P>0.05) between measured and predicted CRF. The Bland-Altman plot illustrates the strong agreement between the two values. Conclusion: We introduced simple and satisfactorily accurate CRF regression equations based in healthy boys. Prediction of CRF of the boys by regression equations would provide a simple tool for assessing cardiorespiratory fitness in large studies including Iranian boys.

7.
Nutrients ; 14(19)2022 Sep 29.
Artículo en Inglés | MEDLINE | ID: mdl-36235712

RESUMEN

The estimation of body fat percentage (%BF) from anthropometry-related data requires population-specific equations to avoid incorrect interpretations in young athletes. Waist girth (WG) has been described as potential predictor of fat mass (FM) in several populations; however, there are no valid WG-based equations to estimate body composition in young Colombian athletes. The aim of this STandardisierte BerichtsROutine für Sekundärdaten Analysen STROSA-based study was twofold: i) to validate the relative fat mass (RFM) and its pediatric version (RFMp) compared to dual-energy x-ray absorptiometry (DXA) and ii) to develop a new equation (F20CA) to estimate the fat mass in Colombian children and adolescent elite athletes. A total of 114 young athletes that belong to the 'Team Medellín' program (58F, 56M; 51 children, 63 adolescents; 14.85 [2.38] years; 55.09 [12.16] kg; 162.38 [11.53] cm) participated in this cross-sectional study. The statistical analysis revealed a poor correlation, agreement and concordance of RFMp and RFM estimations with DXA measurements. After model specification using both Ordinary Least Square method and Bayesian analysis, the regression output revealed that sex, body mass-to-waist ratio, and waist-to-stature ratio were the statistically significant predictor variables that account for variability in FM. The new F20CA equation is expressed as FM (kg) = 5.46 ∗ (Sex) + 0.21 ∗ (BM/W [kg/m]) + 81.7 ∗ (W/Stature [cm/cm]) - 41.8 (R2 = 0.683; SEE = 2.468 kg), where sex is 0 for males and 1 for females. A moderate-to-high correlation and agreement of the F20CA was confirmed within the internal validation data set (R2 = 0.689; ICC [95%CI] = 0.805 [0.615, 0.904]; RMSE = 2.613 kg). The Bland-Altman analysis corroborated the high concordance between the reference method (DXA) and the F20CA-estimated FM (bias [95% LoA] = 1.02 [-3.77, 5.81] kg), indicating the two methods could be considered interchangeable. Even though external validation is needed, practitioners are advised to use the F20CA in young Colombian athletes with similar characteristics to those who participated in this study.


Asunto(s)
Atletas , Composición Corporal , Absorciometría de Fotón/métodos , Adolescente , Antropometría/métodos , Teorema de Bayes , Índice de Masa Corporal , Niño , Colombia , Estudios Transversales , Femenino , Humanos , Masculino
8.
Artículo en Inglés | MEDLINE | ID: mdl-36078407

RESUMEN

Waist girth (WG) represents a quick, simple, and inexpensive tool that correlates with excess of fat mass in humans; however, this measurement does not provide information on body composition. The evaluation of body composition is one of the main components in the assessment of nutritional status. Indeed, the use of anthropometry-based equations to estimate body fat and fat-free mass is a frequent strategy. Considering the lack of validation in the Colombian population, the aim of this research study (the F20 Project) is to externally validate WG-based equations (e.g., relative fat mass), and also to develop and validate new models that include WG to estimate body composition in Colombian adults compared to DXA. This cross-sectional study will be carried out following the guidelines for Strengthening the Reporting of Observational Studies in Epidemiology-Nutritional Epidemiology (STROBE-nut). Using stratified probabilistic sampling, the study population will be adults with different levels of physical activity residing in Medellín and its metropolitan area. The results of this study will not only validate the estimation performance of the current WG-based equations, but they will also develop new equations to estimate body composition in the Colombian population. This will improve professional practice in health, exercise, and sports sciences (ClinicalTrials.gov ID #NCT05450588).


Asunto(s)
Composición Corporal , Nueces , Absorciometría de Fotón , Adulto , Antropometría/métodos , Índice de Masa Corporal , Colombia , Estudios Transversales , Humanos
9.
Biology (Basel) ; 11(9)2022 Sep 16.
Artículo en Inglés | MEDLINE | ID: mdl-36138835

RESUMEN

This study aimed (i) to verify if using and carrying a portable gas analyzer (PGA) constrained the performance of school children on the multistage 20-m shuttle run test (20mSRT), (ii) to verify which peak oxygen consumption (VO2peak) predictive equations have greater agreement with VO2peak values measured by direct oximetry using the 20mSRT. The study participants were 130 children ((67 boys (age 7.76 ± 0.97 years) and 63 girls (age 7.59 ± 0.91 years)), who performed two randomized trials of the 20mSRT with and without a PGA. Twenty-two predictive equations predicted the VO2peak values through the performance of the test with and without a PGA. Without a PGA, lower values of maximal speed (MS), total laps (TL), and total time (TT) were found for girls than for boys with a PGA. Only six equations were considered to correctly predict VO2peak. In general, higher MS, TL, and TT values were found with the use of a PGA. The predicted VO2peak values from the 20mSRT varied significantly among the published predictive equations. Therefore, we suggest that the six equations that presented satisfactory accuracy could be practically used to examine cardiorespiratory fitness in schools and in research with large populations when direct measurement of VO2peak is not feasible.

10.
J Bioinform Comput Biol ; 20(4): 2250018, 2022 08.
Artículo en Inglés | MEDLINE | ID: mdl-35941839

RESUMEN

Whilst data on biochemical networks has increased several-fold, our comprehension of the underlying molecular biology is incomplete and inadequate. Simulation studies permit data collation from disparate time points and the imputed trajectories can provide valuable insights into the molecular biology of complex biochemical systems. Although, stochastic simulations are accurate, each run is an independent event and the data that is generated cannot be directly compared even with identical simulation times. This lack of robustness will preclude a biologically meaningful result for the metabolite(s) of concern and is a significant limitation of this approach. "TemporalGSSA" or temporal Gillespie Stochastic Simulation Algorithm is an R-wrapper which will collate and partition SSA-generated datasets with identical simulation times (trials) into finite sets of linear models (technical replicates). Each such model (time step of a single run, absolute number of molecules for a metabolite) computes several coefficients (slope, intercept, etc.). These coefficients are averaged (mean slope, mean intercept) across all trials of a technical replicate and along with an imputed time step (mean, median, random) is incorporated into a linear regression equation. The solution to this equation is the number of molecules of a metabolite which is used to compute the molar concentration of the metabolite per technical replicate. The summarized (mean, standard deviation) data of this vector of technical replicates is the outcome or numerical estimate of the molar concentration of a metabolite and is dependent on the duration of the simulation. If the SSA-generated dataset comprises runs with differing simulation times, "TemporalGSSA" can compute the time-dependent trajectory of a metabolite provided the trials-per technical replicate constraint is complied with. The algorithms deployed by "TemporalGSSA" are rigorous, have a sound theoretical basis and have contributed meaningfully to our comprehension of the mechanism(s) that drive complex biochemical systems. "TemporalGSSA", is robust, freely accessible and easy to use with several readily testable examples.


Asunto(s)
Algoritmos , Modelos Biológicos , Simulación por Computador , Modelos Lineales , Procesos Estocásticos
11.
Food Sci Nutr ; 9(9): 5006-5015, 2021 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-34532012

RESUMEN

This study investigates the influence of 24-hr marination (with different plant extracts and vinegar) at refrigerated conditions on commonly evaluated physicochemical and textural attributes, including pH, water-holding capacity (WHC), collagen solubility, moisture, drip loss, and shear force values of beef meat. The results reflected the appropriate correlation between each pair and indicated the efficiency of the household marination procedure to acquire more palatability and tender beef meat. Therefore, to predict beef meat tenderness by applying the Warner-Bratzler shear force (WBSF), a strong positive correlation with the drip loss (p < .01) and a notable negative correlation with the moisture content (p < .01) emphasized the importance of moisture improvement and shear force reduction in affecting tenderness of baked beef meat. The regression equations and R-squared values were revealed the favorable correlation between collagen solubility and WHC (y = 0.1035x-0.8431, R 2 = .98) as well as moisture and WBSF (y = -0.3297x + 102.58, R 2 = .99) in marinated beef meat. Electrophoresis patterns of isolated myofibrillar proteins disclosed remarkable degradation of myosin heavy chain (MHC), desmin, actin, and tropomyosin during the first day of aging. The noticeable ultrastructural destruction and connective tissue solubilization were observed by microscopy images. These outcomes were a good tenderness predictor be utilized in retailing and industrial scale.

12.
Exp Gerontol ; 151: 111391, 2021 08.
Artículo en Inglés | MEDLINE | ID: mdl-33984450

RESUMEN

This study analyzed the predictive ability of movement velocity to estimate the relative load (i.e., % of one-repetition maximum [1RM]) during the horizontal leg-press exercise in older women and men. Twenty-four women and fourteen men living in community-dwelling centers volunteered to participate in this study. All participants performed a progressive loading test up to 1RM in the horizontal leg-press. The fastest peak velocity (PV) and mean velocity (MV) attained with each weight were collected for analysis. Linear regression equations were modeled for women and men. We observed very strong linear relationships between both velocity variables and the relative load in the horizontal leg-press in women (PV: r2 = 0.93 and standard error of the estimate (SEE) = 5.96% 1RM; MV: r2 = 0.94 and SEE = 5.59% 1RM) and men (PV: r2 = 0.93 and SEE = 5.96% 1RM; MV: r2 = 0.94 and SEE = 5.97% 1RM). The actual 1RM and the estimated 1RM using both the PV and MV presented trivial differences and very strong relationships (r = 0.98-0.99) in both sexes. Men presented significantly higher (p < 0.001-0.05) estimated PV and MV against all relative loads compared to women (average PV = 0.81 vs. 0.69 m·s-1 and average MV = 0.44 vs. 0.38 m·s-1). Our data suggest that movement velocity accurately estimates the relative load during the horizontal leg-press in older women and men. Coaches and researchers can use the proposed sex-specific regression equations in the horizontal leg-press to implement velocity-monitored resistance training with older adults.


Asunto(s)
Pierna , Entrenamiento de Fuerza , Anciano , Fenómenos Biomecánicos , Femenino , Humanos , Masculino , Fuerza Muscular , Levantamiento de Peso
13.
J Back Musculoskelet Rehabil ; 34(5): 783-793, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33896811

RESUMEN

BACKGROUND: The 6-minute walk test (6-MWT) is commonly used to measure functional capacity in clinical and research settings. The reference equations for predicting the 6-minute walk distance (6-MWD) in different populations have been established; however, there is a lack of information regarding healthy Saudi individuals over 50 years old. OBJECTIVES: This study aimed to establish the reference values of 6-MWD in a sample of healthy Saudi adults aged 50-80 years, develop regression equations for the established 6-MWD, and compare the measured 6-MWD in the present study with the predicted 6-MWD derived from the previously published regression equations. METHODS: In total, 210 healthy Saudi volunteers aged 50-80 years participated in this cross-sectional study. The 6-MWT was performed according to the American Thoracic Society (ATS) guidelines. Lung function, physical activity, blood pressure, heart rate, oxygen saturation, exertion level of leg fatigue, and sensation of dyspnea were measured. RESULTS: The mean 6-MWD was 396.2 ± 69.4 m. It was significantly correlated with age, sex, height, body mass index (BMI), and physical activity. The predictors of 6-MWD were age and BMI for men, while they were age, BMI, and height for women. They accounted for 25% and 35% of the total variance of 6-MWD for men and women, respectively. The measured 6-MWD was significantly shorter than the predicted 6-MWD. CONCLUSION: Saudi populations have significantly shorter 6-MWDs than those reported in other ethnic groups. The sex-specific equations developed in this study are expected to provide a useful measure of 6-MWT for Saudi adults. However, further investigation is required to validate the application of these equations to individuals living in different regions of Saudi Arabia.


Asunto(s)
Prueba de Esfuerzo , Caminata , Adulto , Estudios Transversales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Valores de Referencia , Arabia Saudita
14.
Appl Neuropsychol Adult ; : 1-8, 2021 Mar 24.
Artículo en Inglés | MEDLINE | ID: mdl-33761301

RESUMEN

The Trail Making Test (TMT) is a popular measure of cognitive functioning, especially processing speed and cognitive flexibility. This study aims to provide normative data for the Slovak adult population. The secondary aim is to test the convergent validity by examining relationships of direct and derived indices to other neuropsychological measures. A sample of 487 healthy adults undertook neuropsychological testing. The relationships of TMT scores to demographic variables and other neuropsychological measures were tested. Age was positively correlated with TMT-A (r = 0.444, p < .01), TMT-B (r = 0.426, p < .01), and the B-A index (r = 0.317, p < .01). Years of education were negatively correlated with TMT-B (r = -0.183, p < .01), B-A difference (r = -0.188, p < .01) and B/A ratio (r = -0.119, p < .01). There were no statistically significant differences in performance based on gender. The test scores were correlated with other measures of processing speed and executive functions. Presented normative data are stratified into 7 age categories. For more accurate interpretation, regression equations were calculated to take years of education into account. TMT-A and B performance, as well as B-A difference score, must be interpreted in relation to age, while education can provide additional information. The B/A ratio is independent from age but should be also corrected for educational level.

15.
Anat Cell Biol ; 54(1): 51-58, 2021 Mar 31.
Artículo en Inglés | MEDLINE | ID: mdl-33558448

RESUMEN

Estimation of body length has been achieved from the measurements of the scapular with relative accuracy by researches in recent times. This research hypothesized that the landmarks on the scapular and on the x-ray radiographs could be used to predict scapular length and elucidated the landmarks that best estimate the scapular length. A total of 600 scapulae and 600 anterior-posterior x-ray radiographs were used for the study. Positive correlation was observed between the measured variables and the scapular length with the males showing significantly higher mean length compared to females. The length of axillary boarder of the scapula was the best predictor of the scapular length. No significant difference (P>0.05) existed in the mean length derived from the scapular and the x-ray radiographs of scapular. We therefore conclude that measurements from the radiographs of scapular were as reliable in estimating scapular length as those from the scapular bones.

16.
Trop Anim Health Prod ; 53(1): 44, 2020 Nov 24.
Artículo en Inglés | MEDLINE | ID: mdl-33231754

RESUMEN

Infrared thermography of the lateral side portion of the udder was taken from 38 lactating cows in a 6-day experiment. Thermograms were analyzed using specific software with the use of eight different methods. The experiment was aimed at correlating the different methods with each other and with rectal temperature (RT), in order to suggest a method to assess udder side temperature, and also at creating regression equations to enable RT calculation through the use of thermographic data. All methods of analyzing thermograms were highly correlated; correlations between thermograms and RT were significant (P < 0.01) and above 0.840. The highest correlation was between RT and the maximum temperature obtained using a horizontal rectangle placed within the lateral (side) portion of the udder (maximum temperature in a horizontal rectangle (MHR), 0.897). With the exception of the average temperature of a horizontal rectangle, linear regression coefficients were significant (P < 0.05) and coefficients of determination were higher than 75.51%. We suggest the use of MHR to evaluate udder side temperature. The ease of accessing the side of the udder, the welfare advantages of non-invasive observations, and the high correlation with RT suggest the use of thermograms in the lateral portion of the udder to assess animals' temperature.


Asunto(s)
Glándulas Mamarias Animales/fisiología , Temperatura Cutánea , Termografía/veterinaria , Animales , Temperatura Corporal , Bovinos , Femenino , Termografía/métodos
17.
J Biomech ; 102: 109550, 2020 03 26.
Artículo en Inglés | MEDLINE | ID: mdl-31932024

RESUMEN

Workplace safety assessment, personalized treatment design and back pain prevention programs require accurate subject-specific estimation of spinal loads. Since no noninvasive method can directly estimate spinal loads, easy-to-use regression equations that are constructed based on the results of complex musculoskeletal models appear as viable alternatives. Thus, we aim to develop subject-specific regression equations of L4-L5 and L5-S1 shear and compression forces during various symmetric/asymmetric tasks using a nonlinear personalized finite element musculoskeletal trunk model. Kinematics and electromyography (EMG) activities of 19 young healthy subjects were collected during 64 different symmetric/asymmetric tasks. To investigate the reliability and accuracy of the musculoskeletal model and regression equations, we compared estimated trunk muscle activities and L4-L5 intradiscal pressures (IDPs) respectively with our own electromyography data (EMGs) and reported in vivo pressure measurements. Although in general, six independent rotation components (three trunk T11 rotations and three pelvic S1 rotations) are required to determine kinematics along the spine, only two surrogate variables (trunk flexion and its asymmetric angles) satisfactorily predicted all six rotation components (R2 > 0.94). Regression equations, developed based on subject-specific inputs, predicted spinal loads in satisfactory agreement with IDP measurements (R2 = 0.85). Predicted muscle activities in the personalized musculoskeletal models were in moderate to weak agreements with our measured EMGs in 19 participants. Based on dominance analysis, trunk flexion and its asymmetry angle, hand-load weight, hand-load lever arm, and body weight were the most important variables while the effects of body height and sex on spinal loads remained small.


Asunto(s)
Elevación , Vértebras Lumbares/fisiología , Modelación Específica para el Paciente , Adulto , Fenómenos Biomecánicos , Estatura , Peso Corporal , Humanos , Masculino , Músculo Esquelético/fisiología , Dinámicas no Lineales , Presión , Análisis de Regresión , Reproducibilidad de los Resultados , Soporte de Peso , Adulto Joven
18.
Health Econ ; 29(1): 46-60, 2020 01.
Artículo en Inglés | MEDLINE | ID: mdl-31746059

RESUMEN

Neonatal units in the UK are organised into three levels, from highest Neonatal Intensive Care Unit (NICU), to Local Neonatal Unit (LNU) to lowest Special Care Unit (SCU). We model the endogenous treatment selection of neonatal care unit of birth to estimate the average and marginal treatment effects of different neonatal designations on infant mortality, length of stay and hospital costs. We use prognostic factors, survival and hospital care use data on all preterm births in England for 2014-2015, supplemented by national reimbursement tariffs and instrumental variables of travel time from a geographic information system. The data were consistent with a model of demand for preterm birth care driven by physical access. In-hospital mortality of infants born before 32 weeks was 8.5% overall, and 1.2 (95% CI: -0.7, 3.2) percentage points lower for live births in hospitals with NICU or SCU compared to those with an LNU according to instrumental variable estimates. We find imprecise differences in average total hospital costs by unit designation, with positive unobserved selection of those with higher unexplained absolute and incremental costs into NICU. Our results suggest a limited scope for improvement in infant mortality by increasing in-utero transfers based on unit designation alone.


Asunto(s)
Causalidad , Accesibilidad a los Servicios de Salud/estadística & datos numéricos , Unidades de Cuidado Intensivo Neonatal/estadística & datos numéricos , Modelos Económicos , Nacimiento Prematuro/terapia , Inglaterra , Femenino , Costos de Hospital/estadística & datos numéricos , Hospitales , Humanos , Lactante , Mortalidad Infantil/tendencias , Recién Nacido , Tiempo de Internación/estadística & datos numéricos , Embarazo
19.
Indian J Pediatr ; 87(3): 192-199, 2020 03.
Artículo en Inglés | MEDLINE | ID: mdl-31863388

RESUMEN

OBJECTIVE: To develop regression equations of within and whole-breath respiratory impedance for Indian children aged 5 to 17 y. METHODS: A prospective cross-sectional study was carried out in 5 to 17 y old school children of Bhopal, India. Healthy children were identified by physical examination and by administering questionnaire. The respiratory system resistance (Rrs) and reactance (Xrs) were measured at frequency of 5, 11, and 19 Hz by forced oscillation technique (FOT). The regression equations of within and whole-breath Rrs and Xrs were developed separately for boys and girls by multiple linear regression models. RESULTS: Total 336 children were recruited and data of 320 healthy children (boys - 159), standing height of 146.1 ± 16.6 cm and body mass index of 17.2 ± 2.9 kg/m2 were included in the analysis. The mean respiratory system resistance at 5 Hz (R5) and respiratory system reactance at 5 Hz (X5) of the children, irrespective of gender were 5.46 ± 2.10 cmH2O/L/s and - 1.43 ± 0.85 cmH2O/L/s respectively. Boys of age 16 y and older had significantly smaller Rrs as compared to girls of corresponding age (p < 0.05). The standing height of children had the highest predictive power, followed by age in the regression model. With an increase in standing height, the magnitude of both Rrs and Xrs values of children decrease. The bodyweight of children had a negligible contribution to the regression models. CONCLUSIONS: The regression equations of within- and whole-breath Rrs and Xrs of Indian children aged 5 to 17 y are presented for the first time. The R5 values of Indian children were comparable to children of other ethnicities.


Asunto(s)
Respiración , Pruebas de Función Respiratoria/métodos , Adolescente , Estatura , Índice de Masa Corporal , Peso Corporal , Niño , Preescolar , Estudios Transversales , Femenino , Humanos , India , Masculino , Estudios Prospectivos , Análisis de Regresión , Sistema Respiratorio , Encuestas y Cuestionarios
20.
Ir J Med Sci ; 189(1): 365-372, 2020 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-31230227

RESUMEN

BACKGROUND: Estimating human stature is a major concern to formulate a biological profile which provides effective data for forensic identification. This research was aimed to generate a formula for estimating stature from human foot anthropometry. METHODS: This study was conducted in selected 150 male and 150 female subjects within the range of 18 to 60 years randomly. From each subject, stature and seven-foot measurements were taken by applying the standard technique. Stature was estimated from foot measurements by using linear and multiple regression equations. RESULTS: The result showed that each foot measurement was significantly (p < 0.001) and positively correlated with stature. Bilateral difference among male and female was not significant (p < 0.05). Multiple regression models showed better accuracy in estimating stature than linear regression models. CONCLUSION: In conclusion, it can be said that human stature can be successfully estimated by using foot measurements which can be applied in forensic investigation.


Asunto(s)
Antropometría/métodos , Estatura/genética , Pie/anatomía & histología , Adolescente , Adulto , Bangladesh , Etnicidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven
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