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1.
Dermatol Clin ; 41(3): 491-507, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37236717

RESUMEN

Pediatric dermatoses can present at birth or develop over time. When managing dermatology conditions in children, caregiver involvement is important. Patients may have lesions that need to be monitored or need assistance with therapeutic administration. The following section provides a subset of pediatric dermatoses and notable points for presentation in skin of color patients. Providers need to be able to recognize dermatology conditions in patients of varying skin tones and provide therapies that address the condition and any associated pigmentary alterations.


Asunto(s)
Hiperpigmentación , Recién Nacido , Humanos , Niño , Piel/patología , Pigmentación de la Piel
2.
Biol Rev Camb Philos Soc ; 97(3): 874-895, 2022 06.
Artículo en Inglés | MEDLINE | ID: mdl-34913582

RESUMEN

Skin is a key organ maintaining internal homeostasis by performing many functions such as water loss prevention, body temperature regulation and protection from noxious substance absorption, microorganism intrusion and physical trauma. Skin ageing has been well studied and it is well known that physiological changes in the elderly result in higher skin fragility favouring the onset of skin diseases. For example, prolonged and/or high-intensity pressure may suppress local blood flow more easily, disturbing cell metabolism and inducing pressure injury (PI) formation. Pressure injuries (PIs) represent a significant problem worldwide and their prevalence remains too high. A higher PI prevalence is correlated with an elderly population. Newborn skin evolution has been less studied, but some data also report a higher PI prevalence in this population compared to older children, and several authors also consider this skin as physiologically fragile. In this review, we compare the characteristics of newborn and elderly skin in order to determine common features that may explain their fragility, especially regarding PI risk. We show that, despite differences in appearance, they share many common features leading to higher fragility to shear and pressure forces, not only at the structural level but also at the cellular and molecular level and in terms of physiology. Both newborn and elderly skin have: (i) a thinner epidermis; (ii) a thinner dermis containing a less-resistant collagen network, a higher collagen III:collagen I ratio and less elastin; (iii) a flatter dermal-epidermal junction (DEJ) with lower anchoring systems; and (iv) a thinner hypodermis, resulting in lower mechanical resistance to skin damage when pressure or shear forces are applied. At the molecular level, reduced expression of transforming growth factor ß (TGFß) and its receptor TGFß receptor II (TßRII) is involved in the decreased production and/or increased degradation of various dermal extracellular matrix (ECM) components. Epidermal fragility also involves a higher skin pH which decreases the activity of key enzymes inducing ceramide deficiency and reduced barrier protection. This seems to be correlated with higher PI prevalence in some situations. Some data also suggest that stratum corneum (SC) dryness, which may disturb cell metabolism, also increases the risk of PI formation. Besides this structural fragility, several skin functions are also less efficient. Low applied pressures induce skin vessel vasodilation via a mechanism called pressure-induced vasodilation (PIV). Individuals lacking a normal PIV response show an early decrease in cutaneous blood flow in response to the application of very low pressures, reflecting vascular fragility of the skin that increases the risk of ulceration. Due to changes in endothelial function, skin PIV ability decreases during skin ageing, putting it at higher risk of PI formation. In newborns, some data lead us to hypothesize that the nitric oxide (NO) pathway is not fully functional at birth, which may partly explain the higher risk of PI formation in newborns. In the elderly, a lower PIV ability results from impaired functionality of skin innervation, in particular that of C-fibres which are involved in both touch and pain sensation and the PIV mechanism. In newborns, skin sensitivity differs from adults due to nerve system immaturity, but the role of this in PIV remains to be determined.


Asunto(s)
Úlcera por Presión , Factor de Crecimiento Transformador beta , Enfermedades Vasculares , Adolescente , Adulto , Anciano , Niño , Humanos , Recién Nacido , Colágeno , Matriz Extracelular , Fenómenos Fisiológicos de la Piel , Factor de Crecimiento Transformador beta/metabolismo
3.
Glob Pediatr Health ; 6: 2333794X19835668, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-30956996

RESUMEN

The majority of neonatal cutaneous conditions are benign and self-limited. However, some skin infections and specific birthmarks are serious and require proper management approaches. This study was a prospective survey of 1000 consecutive newborns at a tertiary care center in Northeast Thailand from September 2015 to 2016, which aimed to identify various cutaneous findings in newborns during their first 5 days of life. The authors found that Mongolian spots (66.7%) and sebaceous gland hyperplasia (60.9%) were the 2 most common cutaneous conditions found in the Thai population. Salmon patches were the most frequent vascular birthmarks (36%), followed by infantile hemangiomas (1.1%) and port wine stains (0.7%). Although majority of the neonatal cutaneous conditions are benign and self-limited, there were 8 cases (0.8%) of bullous impetigo in which both systemic and topical antibiotics were promptly prescribed.

4.
Nurs Womens Health ; 21(6): 442-450, 2017 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-29223208

RESUMEN

There has been a recent trend toward delaying newborn baths because of mounting evidence that delayed bathing promotes breastfeeding, decreases hypothermia, and allows for more parental involvement with newborn care. A multidisciplinary team from a maternal-new-born unit at a military medical center designed and implemented an evidence-based practice change from infant sponge baths shortly after birth to delayed immersion baths. An analysis of newborn temperature data showed that newborns who received delayed immersion baths were less likely to be hypothermic than those who received a sponge bath shortly after birth. Furthermore, parents reported that they liked participating in bathing their newborns and that they felt prepared to bathe them at home.


Asunto(s)
Baños/métodos , Salud del Lactante/normas , Padres/educación , Cuidados de la Piel/métodos , Factores de Tiempo , Lactancia Materna/métodos , Lactancia Materna/tendencias , Femenino , Humanos , Hipotermia/prevención & control , Inmersión , Cuidado del Lactante/métodos , Cuidado del Lactante/tendencias , Recién Nacido , Estudios Retrospectivos , Cuidados de la Piel/tendencias , Encuestas y Cuestionarios , Estados Unidos
5.
Clin Pediatr (Phila) ; 56(5_suppl): 16S-22S, 2017 May.
Artículo en Inglés | MEDLINE | ID: mdl-28420251

RESUMEN

Mild diaper dermatitis often occurs in children before toilet training is complete, particularly from 9 to 12 months of age, and the most common presentation is an irritant contact dermatitis. Diaper dermatitis may account for up to 25% of dermatology visits to health care providers during the first year of life. Fortunately, since the introduction of hypoallergenic, superabsorbent modern disposable diapers, the incidence and severity of irritant and allergic contact dermatitis has decreased dramatically. Diaper dermatitis broadly refers to skin disorders that occur in the diaper area, such as skin eruptions triggered by diapers, rashes exacerbated by the diaper, and other events that occur in the diaper area. A number of skin conditions that can occur anywhere on the skin may present with distinctive findings in the diaper area. The following discussion will review the most common triggers of diaper dermatitis and contact irritant dermatitis, while focusing on the skin conditions that may be associated or overlap clinically with contact dermatitis.


Asunto(s)
Diagnóstico Diferencial , Dermatitis del Pañal/diagnóstico , Enfermedad Aguda , Candidiasis Cutánea/etiología , Dermatitis por Contacto/etiología , Dermatitis del Pañal/complicaciones , Dermatitis del Pañal/patología , Pañales Infantiles , Equipos Desechables , Femenino , Humanos , Lactante , Recién Nacido , Queratosis Seborreica/patología , Masculino , Infecciones Cutáneas Estafilocócicas/etiología
6.
Nurs Womens Health ; 19(5): 422-9, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26460914

RESUMEN

Diaper dermatitis in infants is commonly seen by clinicians in both primary care and acute care settings. The condition can cause significant discomfort for infants and distress for their parents and caregivers. Nursing for Women's Health convened a group of nursing clinicians who work in a variety of settings to discuss the issues and challenges related to preventing and treating diaper dermatitis in both healthy term newborns and premature newborns.


Asunto(s)
Dermatitis del Pañal/terapia , Lactancia Materna , Dermatitis del Pañal/enfermería , Dermatitis del Pañal/patología , Humanos , Recién Nacido , Recien Nacido Prematuro/metabolismo
7.
Nurs Womens Health ; 19(4): 324-36; quiz 337, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26264797

RESUMEN

Diaper dermatitis is a common cutaneous condition characterized by an acute inflammatory eruption of the skin in the diaper area of an infant. Although this condition is relatively common, it can cause considerable pain and stress for infants and can be troublesome for their caregivers. In the United States, the frequency of diaper dermatitis is substantial and accounts for a high number of visits to health care providers. The three most common types of diaper dermatitis are chafing dermatitis, irritant contact dermatitis and diaper candidiasis. This article reviews common causes, differential diagnosis, current prevention and treatment recommendations, nursing implications and practical tips for families to utilize while caring for their infants at home.


Asunto(s)
Dermatitis del Pañal/prevención & control , Dermatitis del Pañal/terapia , Educación Continua en Enfermería , Padres/educación , Humanos , Lactante , Recién Nacido
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