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In the article, the authors identified the most attractive areas for investment in the Far Eastern Federal District based on statistical data on the agriculture and processing industry. The authors presented a set of secondary data from the Federal State Statistics Service and the Investment Projects Digital Platform, which reflect the cost of implementing projects in the Far Eastern Federal District. These data were presented to characterize the region as deeply diversified, with a predominance of the livestock and fishing sectors. The authors identified the most promising investment projects in various regions of the Far Eastern Federal District and assessed their attractiveness in terms of accessibility to transportation. The result was a map of the implementation of the main areas of investment activity, taking into account transport connectivity. In addition, recommendations have been drawn for the development of agriculture in the Far Eastern Federal District. These recommendations deserve the attention not only of government specialists but also of all stakeholders involved in agricultural production.

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The article provides a quantitative assessment of the socioeconomic potential of the territories of advanced development (TAD) of the regions of the Far Eastern Federal District (FEFD). The key indicators of the TAD of the Far Eastern Federal District are considered, their contribution to the dynamics of investments in fixed assets and employment of the regions of the Far Eastern Federal District is determined, groups of regions of the Far Eastern Federal District are identified according to the degree of influence of the TAD on the parameters of social, economic and investment development, the industry specialization of the TAD is analyzed, the contribution of the TAD to investment and employment is assessed in the economy of the Far Eastern Federal District until 2024.

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This article analyzes the main indicators of the incidence and life expectancy of the population of the Republic of Sakha (Yakutia) over a twenty-year period. An increase in the incidence rate of the population was revealed that exceeded the average for the country and the Far Eastern Federal District, including for oncological diseases, the level of which increased several times in the republic. The value of the indicator of life expectancy in the republic approached the average Russian level, while 20 years ago a much lower indicator was determined. In the dynamics of indicators of the morbidity of the population and life expectancy over a twenty-year period, a polynomial trend has been outlined. For example, the incidence of neoplasms and diseases of the circulatory system showed a sharp increase in 2004, followed by a decrease, for diseases of the digestive system - similarly, an increase in 2001 and a subsequent decrease. This aspect requires an additional detailed study of the causes of such changes in order to be able to predict them in the future.

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BACKGROUND: Diseases characterized by elevated blood pressure are the most frequently diagnosed pathology among socially significant diseases in the Russian Federation. According to clinical recommendations of the Russian Medical Society for Arterial Hypertension 2010-2019, the use of two and more component drugs improves the compliance of patients to treatment. The purpose of this study was a comparative analysis of preferences in the usage of combined antihypertensive drugs in ten regions of the Far Eastern Federal District (FSD). MATERIALS AND METHODS: Intra-group analysis of data on the sale of antihypertensive drugs in pharmacy organizations (162 drugstores) for the period 2018 was carried out in the 10 regions of the FSD. The sample is uneven due to the difference in total number of drugstores in the regions. The sample was random. Pharmacies were in urban and rural areas. The total purchase of all defined daily doses of all antihypertensive drugs was taken as 100%. Then, fixed-dose combinations were selected. The share of each drug in the sales structure was then calculated. Kruskal-Wallis criterion was used for determining the differences in the structure of acquisition of drugs between the regions. The Spearman's rank correlation and factor analysis were used for determining the correlation between the drug's acquisition structure and the FSD region. RESULTS: Two-component drugs are most in demand in the Amur region - 15.2% and Zabaykalsky Krai - 12.3%, and the lowest demand in the Sakhalin region - 5.25% and Magadan region - 6.5%. The largest sales indicators of three-component drugs were observed in the Zabaykalsky Krai - 1.2% and the Republic of Buryatia - 1.0%. The most acquired combinations were atenolol+chlorthalidone, valsartan+amlodipine, losartan+hydrochlorothiazide, perindopril/lisinopril/ramipril+amlodipine, perindopril+indapamide. CONCLUSION: Group leaders may vary depending on the region, which is due to the preferences of medical specialists. However, the differences are not significant, which proves the unity of approaches to combined drug therapy of arterial hypertension.