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1.
Int J Life Cycle Assess ; 29(9): 1756-1763, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39220436

RESUMEN

Purpose: Marine vertebrate populations have halved in the past decades, and invasive species are a major driver for this loss. While many model the spread of invasive species, a model to assess impacts of marine invasions, after introduction, has hitherto been missing. We present the first regionalized effect factors for marine invasions. These factors gauge differences in biodiversity impacts after invasions, enabling life cycle impact assessments to highlight biodiversity impacts from invasive species. Methods: Alien species are species that are introduced by humans to ecosystems where they are not native. We combine data from the IUCN red list and the MarINvaders database to identify the potentially disappeared fraction of native species within each marine coastal ecoregion after alien introduction. The effect factors indicate the biodiversity impact from invasions per alien introduction. However, the IUCN red list has a performance bias between taxonomic groups, and both the IUCN and the harmonized citizen science data from MarINvaders have a geographic observer's bias. We address some of this bias by evaluating the number of threatened species per number of assessed species, as well as including machine-learning derived data for data deficient species. Results and discussion: The resulting regional effect factors demonstrate high effects of invasions at high latitudes, which is in line with other findings. Our approach is founded on continuously growing citizen science data and so reflects the biases and uncertainties that follow with this uneven way of data sampling. On the other hand, the continuous data collection by citizen scientists will improve data coverage and thus improve the model. Vice versa, the model itself may be motivation for citizens scientists to collect more data. Conclusion: The effect of marine invasions presented herein reflects current global information on the issue viewed in a perspective relevant for life cycle impact assessments. The developed effect factors can be used for further assessments that will aid decision-making for policies, industries, and consumers to work towards minimizing impacts of marine invasions and are developed to be compatible with different relevant fate factors. Supplementary Information: The online version contains supplementary material available at 10.1007/s11367-024-02325-7.

2.
Environ Sci Ecotechnol ; 22: 100453, 2024 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-39175512

RESUMEN

Marine protected areas (MPAs) across various countries have contributed to safeguarding coastal and marine environments. Despite these efforts, marine non-native species (NNS) continue to threaten biodiversity and ecosystems, even within MPAs. Currently, there is a lack of comprehensive studies on the inventories, distribution patterns, and effect factors of NNS within MPAs. Here we show a database containing over 15,000 occurrence records of 2714 marine NNS across 16,401 national or regional MPAs worldwide. To identify the primary mechanisms driving the occurrence of NNS, we utilize model selection with proxies representing colonization pressure, environmental variables, and MPA characteristics. Among the environmental predictors analyzed, sea surface temperature emerged as the sole factor strongly associated with NNS richness. Higher sea surface temperatures are linked to increased NNS richness, aligning with global marine biodiversity trends. Furthermore, human activities help species overcome geographical barriers and migration constraints. Consequently, this influences the distribution patterns of marine introduced species and associated environmental factors. As global climate change continues to alter sea temperatures, it is crucial to protect marine regions that are increasingly vulnerable to intense human activities and biological invasions.

3.
Stem Cells ; 42(7): 581-592, 2024 Jul 08.
Artículo en Inglés | MEDLINE | ID: mdl-38655883

RESUMEN

Fully grown oocytes have the natural ability to transform 2 terminally differentiated gametes into a totipotent zygote representing the acquisition of totipotency. This process wholly depends on maternal-effect factors (MFs). MFs stored in the eggs are therefore likely to be able to induce cellular reprogramming to a totipotency state. Here we report the generation of totipotent-like stem cells from mESCs using 4MFs Hsf1, Zar1, Padi6, and Npm2, designated as MFiTLSCs. MFiTLSCs exhibited a unique and inherent capability to differentiate into embryonic and extraembryonic derivatives. Transcriptomic analysis revealed that MFiTLSCs are enriched with 2-cell-specific genes that appear to synergistically induce a transcriptional repressive state, in that parental genomes are remodeled to a poised transcriptional repression state while totipotency is established following fertilization. This method to derive MFiTLSCs could help advance the understanding of fate determinations of totipotent stem cells in a physiological context and establish a foundation for the development of oocyte biology-based reprogramming technology.


Asunto(s)
Células Madre Totipotentes , Animales , Ratones , Células Madre Totipotentes/metabolismo , Células Madre Totipotentes/citología , Diferenciación Celular/genética , Femenino , Reprogramación Celular/genética , Oocitos/metabolismo , Oocitos/citología
4.
Molecules ; 29(5)2024 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-38474623

RESUMEN

Extra virgin olive oil (EVOO) is recognized for its numerous health benefits, attributed to its rich phenolic components. NMR has emerged as a prevalent technique for precisely identifying these compounds. Among Mediterranean countries, Greece stands as the third-largest producer of olives, with the Epirus region notably advancing in olive cultivation, contributing significantly to the dynamic growth of the region. In this study, an NMR method was employed based on the acquisition of a 1H NMR spectrum along with multiple resonant suppression in order to increase the sensitivity. Using the above method, 198 samples of extra virgin olive oil, primarily sourced from the Epirus region, were analyzed, and both the qualitative and quantitative aspects of the phenolic compounds were obtained. In addition, we examined the effects of various factors such as variety, harvest month, and region origin on the phenolic compounds' concentration. The results revealed an average total phenolic content of 246 mg/kg, closely approaching the EU health claim limit of 250 mg/kg. Approximately 15% of the samples were confidently characterized as high-phenolic olive oil. The highest concentrations were observed in the Thesprotia samples, with several Lianolia varieties exceeding the total phenolic content of 400 mg/kg. Statistical tests demonstrated a significant influence of the olive variety and the month of fruit harvest on phenolic component concentration, followed by the region of origin. A very strong correlation was noted between the total phenolics content and the levels of oleocanthal and oleacein, with a correlation coefficient (r) of 0.924. Upon optimization of all factors affecting olive oil quality, the majority of the EVOOs from the Epirus region have the potential to be characterized as high in phenolic content.


Asunto(s)
Olea , Aceite de Oliva/química , Grecia , Olea/química , Espectroscopía de Resonancia Magnética , Imagen por Resonancia Magnética
5.
Saudi J Med Med Sci ; 11(2): 135-142, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37252021

RESUMEN

Background: Feeding intolerance (FI) is a prevalent cause of enteral nutrition (EN) disruption. Factors that can prevent FI are poorly described. Objectives: To determine the prevalence and risk factors associated with FI in critically ill patients and the effectiveness of preventive treatments. Patients and Methods: This prospective observational study included critically ill patients admitted to the ICU of a general hospital who received EN through a nasogastric or nasointestinal tube from March 2020 to October 2021. Independent sample t-test, repeated measurement analysis of variance, and multivariate analysis were used to explore independent risk factors and the efficacy of preventive treatments. Results: The study included 200 critically ill patients (mean age: 59.1 ± 17.8 years), of whom 131 were male. Most patients (58.50%) developed FI after a median EN duration of 2 days. The independent risk factors for FI were fasting for >3 days, high APACHE II score, and acute gastrointestinal injury (AGI) grade I before EN (P < 0.05). During EN, whole protein was found to be an independent preventive treatment that significantly decreased FI (P < 0.05), while before EN, early use of enema and gastric motility drugs in patients with abdominal distention/constipation significantly decreased FI (for both, P < 0.05). The preventive treatment group had significantly higher intake of the nutrient solution and significantly shorter invasive mechanical ventilation duration than the without preventive treatment group (for both, P < 0.05). Conclusion: In ICU patients receiving nasogastric or nasointestinal tube feeding, FI was frequent, occurred early, and was more frequent in patients with fasting >3 days, a high APACHE II score, and an AGI grade before EN. Preventive treatments can reduce FI prevalence and result in patients consuming more nutrient solutions and having shorter invasive mechanical ventilation duration. Chinese Clinical Trial Registry Registration no: ChiCTR-DOD-16008532.

6.
Environ Sci Technol ; 57(22): 8347-8354, 2023 06 06.
Artículo en Inglés | MEDLINE | ID: mdl-37216582

RESUMEN

The increasing application of synthetic fertilizer has tripled nitrogen (N) inputs over the 20th century. N enrichment decreases water quality and threatens aquatic species such as fish through eutrophication and toxicity. However, the impacts of N on freshwater ecosystems are typically neglected in life cycle assessment (LCA). Due to the variety of environmental conditions and species compositions, the response of species to N emissions differs among ecoregions, requiring a regionalized effect assessment. Our study tackled this issue by establishing regionalized species sensitivity distributions (SSDs) of freshwater fish against N concentrations for 367 ecoregions and 48 combinations of realms and major habitat types globally. Subsequently, effect factors (EFs) were derived for LCA to assess the effects of N on fish species richness at a 0.5 degree × 0.5 degree resolution. Results show good SSD fits for all of the ecoregions that contain sufficient data and similar patterns for average and marginal EFs. The SSDs highlight strong effects on species richness due to high N concentrations in the tropical zone and the vulnerability of cold regions. Our study revealed the regional differences in sensitivities of freshwater ecosystems against N content in great spatial detail and can be used to assess more precisely and comprehensively nutrient-induced impacts in LCA.


Asunto(s)
Ecosistema , Nitrógeno , Animales , Peces/fisiología , Agua Dulce , Calidad del Agua , Biodiversidad
7.
J Environ Manage ; 339: 117760, 2023 Aug 01.
Artículo en Inglés | MEDLINE | ID: mdl-37031601

RESUMEN

Sewage in wastewater treatment plants (WWTPs) can produce fugitive bioaerosols that pose a health risk to employees and residents. This study aimed to fugitive bioaerosols from two WWTPs with anaerobic-anoxic-oxic (AAO) processes, and bioaerosols control measures were proposed based on the results of these studies. It was found that the bioaerosols were mainly composed of microorganisms from dominant genera such as Romboutsia, Rubellimicrobium, Sphingomonas, Acidea, Cryptotrichosporon and water-soluble ions dominated by SO42-. Moreover, total suspended particulate (TSP), relative humidity (RH), wind speed (WS), Ca2+, NH4+, Na+, Cl-, NO3-, and K+ had positive effects on most dominant genera, while temperature (T) and SO42- had negative effects on most dominant genera. The source analysis showed that the bioaerosols in the indoor treatment facility's fine screen room and sludge dewatering plant mainly originated from sewage or sludge, and those in the aeration tank of the outdoor treatment facility mainly originated from the background air of WWTPs . By combining the characteristics of bioaerosols and the results of source analysis, targeted control measures were proposed from three aspects: source reduction of bioaerosol fugitives, control of bioaerosol propagation, and collection and treatment systems. This study provides the theoretical basis and ideas for controlling bioaerosols in WWTPs with AAO processes.


Asunto(s)
Aguas del Alcantarillado , Purificación del Agua , Humanos , Aguas Residuales , Anaerobiosis , Aerosoles
8.
Aust Crit Care ; 36(4): 464-469, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-36104256

RESUMEN

BACKGROUND: Patients transferred from the respiratory intensive care unit (ICU) can experience post-intensive care syndrome (PICS), which comprises cognitive, psychological, and physical disorders that seriously affect the quality of life. Therefore, it was necessary to explore the incidence of and the risk factors for PICS among respiratory ICU patients. OBJECTIVES: This study evaluated PICS among respiratory ICU patients and explored the risk factors for PICS. METHODS: This cross-sectional, prospective study was performed at one hospital in China. Using convenience sampling, 125 respiratory ICU patients from August 2018 to June 2019 were recruited for the study. The Mini-Mental State Examination, Confusion Assessment Method for the Intensive Care Unit, Hospital Anxiety and Depression Scale, Medical Research Council Scale, activities of daily living scale, Pittsburgh Sleep Quality Index, and the 14-item fatigue scale were used to comprehensively assess the patients' cognitive status, psychological status, and physiological status when entering the ICU and 2 weeks after leaving the ICU. Factors affecting PICS were measured using researcher-created questionnaires of patients' general information and disease-related information. RESULTS: Fifteen patients were lost to follow-up. Fifty-nine patients had PICS (incidence rate, 53.6%). Logistic regression showed that risk factors for PICS were age, invasive mechanical ventilation, noninvasive ventilator-assisted ventilation, and coronary heart disease (P < 0.05). CONCLUSION: The PICS incidence was high. Older age, longer invasive mechanical ventilation times, longer noninvasive ventilator times, and coronary heart disease were risk factors for PICS. ICU medical workers in China should pay more attention on PICS, know the risk factors, and implement preventive measures.


Asunto(s)
Actividades Cotidianas , Calidad de Vida , Humanos , Estudios Prospectivos , Incidencia , Estudios Transversales , Pueblos del Este de Asia , Unidades de Cuidados Intensivos , Factores de Riesgo
9.
J Colloid Interface Sci ; 633: 1012-1021, 2023 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-36516677

RESUMEN

HYPOTHESIS: Classical (solid particles stabilized) Pickering emulsions have been widely studied due to the irreversible adsorption of solid particles at the oil-water interface. Mesoporous hollow silica microspheres (MHSMs) are promising stabilizers for Pickering emulsion owing to its larger specific surface area and lower apparent density. However, this type of Pickering emulsion has not attracted enough attention. The stabilization mechanism of Pickering emulsion by MHSMs has not been studied in detail yet. EXPERIMENTS: Herein, stable Pickering emulsions were prepared using only MHSMs as stabilizers. In order to investigate its stabilization mechanism, the effect factors of size, shell thickness, wettability and concentration of MHSMs, and oil/water ratio on the stability of Pickering emulsions were analyzed deeply. FINDINGS: As a result, the stability of Pickering emulsion can be improved by MHSMs with smaller particle size and shell thickness. Also, MHSMs with the intermediate hydrophobicity and suitable oil/water ratio actually do favour for the stability of Pickering emulsion. As expected, the stability of Pickering emulsion can be enhanced by increasing the concentration of MHSMs in a certain range. The Pickering emulsions tend to achieve excellent stable state when the concentration of MHSMs is 1.25 mg/mL. All those results suggested that the stability of Pickering emulsions correlates directly to particle size, shell thickness, wettability and concentration of MHSMs, and oil/water ratio. This research paves a way for the fabrication of functional materials via Pickering emulsions.


Asunto(s)
Dióxido de Silicio , Emulsiones , Microesferas , Humectabilidad , Interacciones Hidrofóbicas e Hidrofílicas , Tamaño de la Partícula
10.
Front Public Health ; 11: 1219199, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-38186709

RESUMEN

Non-communicable diseases (NCDs) are the leading cause of death worldwide. NCDs affect the health status and the quality of life. In addition, continuous NCDs treatment expenses place a heavy economic burden on families and cause huge economic losses to the society. The prevention and treatment of NCDs and reduction of their economic burden are key public health issues. Considering middle-aged and older adult people as the focus, their basic socio-demographic characteristics and health behavior status of this group, and a pooled cross-sections regression model was then used to analyze the main factors affecting the direct economic burden. The results showed that from 2013 to 2018, the prevalence of NCDs among the middle-aged and older adult people in Shaanxi province as well as the direct economic burden of NCDs increased. The effect factors primarily included sex, age, employment status, income level, type of medical insurance, urban or rural residency, level of the health care-providing institutions, visiting times of 2-week, and length of hospital stay. Several measures can be taken to control the onset of NCDs and reduce their direct economic burden.


Asunto(s)
Estrés Financiero , Enfermedades no Transmisibles , Persona de Mediana Edad , Humanos , Anciano , Recién Nacido , Enfermedades no Transmisibles/epidemiología , Enfermedades no Transmisibles/terapia , Calidad de Vida , Conductas Relacionadas con la Salud , Estado de Salud
11.
Ecol Inform ; 69: 101674, 2022 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-36568861

RESUMEN

In this study, mean monthly and diurnal variations in fine particulate matters (PM2.5), nitrate, sulfate, and gaseous precursors were investigated during the Level 3 COVID-19 alert from May 19 to July 27 in 2021. For comparison, the historical data during the identical period in 2019 and 2020 were also provided to determine the effect of the Level 3 COVID-19 alert on aerosols and gaseous pollutants concentrations in Taichung City. A machine learning model using the artificial neural network technique coupled with a kinetic model was applied to predict NOx, O3, nitrate (NO3 -), and sulfate (SO4 2-) to investigate potential emission sources and chemical reaction mechanism. D during the Level 3 COVID-19 alert, a decrease in NOx concentration due to a decrease in traffic flow under the NOx-saturated regime was observed to enhance the secondary NO3 - and O3 formation. The present models were shown to predict 80.1, 77.0, 72.6, and 67.2% concentrations of NOx, O3, NO3 -, and SO4 2-, respectively, which could help decision-makers for pollutant emissions reduction policies development and air pollution control strategies. It is recommended that more long-term datasets, including water soluble inorganic salts (WIS), precursors including OH radicals, NH3, HNO3, and H2SO4, be provided by regulatory air quality monitoring stations to further improve the prediction model accuracy.

12.
Sci Total Environ ; 850: 157843, 2022 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-35934027

RESUMEN

Freshwater biodiversity and ecosystem services may decline because of toxicant input, and other environmental variables often co-occur with contaminants to jeopardize the freshwater ecosystem. In this study, Danjiangkou Reservoir (DJKR) in central China was selected as the target research area to investigate the impact of multiple categories of micropollutants coupled with other stressors on the reservoir ecosystem. A total of 140 samples were collected from 28 sites in DJKR, and 124 micropollutants, including pesticides, organophosphate esters (OPEs), psychoactive substances, antiviral drugs, and pharmaceutical and personal care products, were quantified. A total of 108 micropollutants were detected in the water samples, with sum concentrations ranging from 82.35 ng·L-1 to 1436.57 ng·L-1, and 71 of them had a detection frequency above 50 %, indicating the prevailing micropollutant contamination in the reservoir. The most severe pollution and risks were observed in the tributaries of DJKR. Pesticides (neonicotinoid and triazine) and OPEs were the major contributors to the ecological risk in the reservoir. Insecticides, herbicides, and OPEs accounted for the majority of the risks to fish, algae, and invertebrates, respectively. The determined priority pollutants should be paid increased attention. Environmental variables and human activities, such as human land use, induced the potential aquatic threats of micropollutants in DJKR. Results demonstrated that micropollutant pollution was one of the dominant pressures faced by aquatic organisms and human beings, and human activities played important roles as well.


Asunto(s)
Contaminantes Ambientales , Herbicidas , Insecticidas , Plaguicidas , Contaminantes Químicos del Agua , Animales , Antivirales , Ecosistema , Monitoreo del Ambiente/métodos , Ésteres , Actividades Humanas , Humanos , Lagos , Neonicotinoides , Organofosfatos , Plaguicidas/análisis , Preparaciones Farmacéuticas , Triazinas , Agua , Contaminantes Químicos del Agua/análisis
13.
J Hazard Mater ; 410: 124686, 2021 05 15.
Artículo en Inglés | MEDLINE | ID: mdl-33309139

RESUMEN

Wastewater treatment plants (WWTPs) associated bioaerosols have emerged as one of the critical sustainability indicators, ensuring health and well-being of societies and cities. In this context, this review summarizes the various wastewater treatment technologies which have been studied with a focus of bioaerosols emissions, potential emission stages, available sampling strategies, survival and dispersion factors, dominant microbial species in bioaerosols, and possible control approaches. Literature review revealed that most of the studies were devoted to sampling, enumerating and identifying cultivable microbial species of bioaerosols, as well as measuring their concentrations. However, the role of treatment technologies and their operational factors are investigated in limited studies only. Moreover, few studies have been reported to investigate the presence and concentrations of air borne virus and fungi in WWTP, as compared to bacterial species. The common environmental factors, affecting the survival and dispersion of bioaerosols, are observed as relative humidity, temperature, wind speed, and solar illumination. Further, research studies on recent episodes of COVID-19 (SARS-CoV-2 virus) pandemic also revealed that continuous and effective surveillance on WWTPs associated bioaerosols may led to early sign for future pandemics. The evaluation of reported data is bit complicated, due to the variation in sampling approaches, ambient conditions, and site activities of each study. Therefore, such studies need a standardized methodology and improved guidance to help informed future policies, contextual research, and support a robust health-based risk assessment process. Based on this review, an integrated sampling and analysis framework is suggested for future WWTPs to ensure their sustainability at social and/or health associated aspects.


Asunto(s)
Aerosoles/análisis , Microbiología del Aire , Bacterias/clasificación , Hongos/clasificación , Virus/clasificación , Humanos , Especificidad de la Especie , Purificación del Agua
14.
J Clin Lab Anal ; 34(2): e23057, 2020 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-31663630

RESUMEN

BACKGROUND: Renal failure is a severe complication of symptomatic myeloma, related to higher mortality. Recovery from dialysis dependence can lead to enormous survival benefits. We investigated the effect factors for probability of dialysis independence. METHODS: Retrospective data on 45 newly diagnosed MM (NDMM) patients with serious renal impairment and requiring hemodialysis were analyzed. The statistical methods including logistic regression analysis, Kaplan-Meier survival curves, the log-rank test and the Cox proportional hazards model for survival analysis were used in our study. RESULTS: Twenty-two of the 45 patients, who were on hemodialysis at diagnosis, became dialysis independence. In the logistic regression analysis, serum level of ß2-microglobulin, kidney disease history, involved free light chain, and achieving at least VGPR were significantly associated with reversibility from dialysis dependence. In addition, achieving hemodialysis discontinuation was related to better survival. The multivariate analyses demonstrated that reversibility from dialysis dependence, proteinuria < 3.5 g/24 h, and achieving at least VGPR were significantly associated with OS among NDMM patients requiring hemodialysis. CONCLUSION: Lower serum level of ß2-microglobulin and lower level of free light chain at diagnosis, achieving at least VGPR, and shorter kidney disease history are related to a high probability of dialysis independence in NDMM patients with serious renal failure requiring dialysis.


Asunto(s)
Mieloma Múltiple/mortalidad , Mieloma Múltiple/terapia , Diálisis Renal , Adulto , Anciano , Anciano de 80 o más Años , Protocolos de Quimioterapia Combinada Antineoplásica/efectos adversos , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Femenino , Tasa de Filtración Glomerular , Humanos , Estimación de Kaplan-Meier , Fallo Renal Crónico/terapia , Masculino , Persona de Mediana Edad , Mieloma Múltiple/fisiopatología , Modelos de Riesgos Proporcionales , Estudios Retrospectivos , Resultado del Tratamiento
15.
Sci Prog ; 103(1): 36850419881866, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-31829896

RESUMEN

The study of phase-change heat-transfer characteristics of crude oil has been one of the hot issues in the field of gathering and transportation. The process of phase-change heat transfer of crude oil involves many complicated problems such as natural convection treatment, latent heat treatment, phase-change interface determination and fluid characteristic change. A mathematical model based on the additional capacity heat method is proposed in this article, and the momentum equations of crude oil liquid phase are presented for Newtonian and non-Newtonian fluids. The aim of this study was to investigate the influence of different factors on the heat transfer performance during the shutdown process of an overhead pipe. Experiments were conducted to verify the model and the solution method; the experimental and model results showed good agreement with a maximum relative error of 4.57%. The temperature fields and solidification conditions of crude oil in pipelines under different shutdown conditions were determined, and the sensitivity of the main effect factors was determined through an orthogonal experiment. The results show that the order of influence was oil initial temperature >thickness of insulating layer >air temperature >thickness of wax layer. The results of the study have important guiding significance on the control of shutdown time and the determination of restarting schemes.

16.
J Orthop Surg Res ; 14(1): 161, 2019 May 28.
Artículo en Inglés | MEDLINE | ID: mdl-31138291

RESUMEN

OBJECTIVES: This study aimed to investigate the effect factors associated with the postoperative dissatisfaction of patients undergoing open-door laminoplasty for cervical OPLL. METHODS: In this study, 194 patients, who underwent open-door laminoplasty for cervical OPLL from January 2009 to January 2016, were retrospectively reviewed. The Patient Satisfaction Index (PSI) was collected at discharge, 6 months, 1 year, and the last follow-up. According to the PSI, patients were divided into satisfied group and dissatisfied group. The possible effect factors included demographic variables and surgery-related variables. RESULTS: At discharge, 42 (21.6%) patients were in the dissatisfied group, as compared to the satisfied group, the hospitalization cost, hospital stay, postoperative depression, the axial neck pain, delayed wound healing, and VAS-neck had significant statistical differences. At 6-month follow-up, 25 (12.9%) patients were in the dissatisfied group. The axial neck pain and JOA score had significant statistical differences between the two groups, and no significant differences were found between the two groups in other items. At 1 year with 18 (9.3%) dissatisfied patients and last follow-up with 14 (7.2%) dissatisfied patients, the JOA score and symptom recurrence had significant statistical differences. For further analysis, the dissatisfied patients with axial neck pain at 6 months were significantly higher than that at other terms and the JOA score of the two groups increased gradually with prolonging of restoration years but compared with the dissatisfied group, the JOA scores were obviously better in the satisfied group at the last follow-up. CONCLUSIONS: Overall, to patients undergoing open-door laminoplasty for cervical OPLL, hospitalization cost and neck pain might be mainly associated with patient dissatisfaction at the early and middle recovery. Patient dissatisfaction at the long-term treatment outcome might be mainly associated with the low improvement rate of JOA score and symptom recurrence.


Asunto(s)
Vértebras Cervicales/cirugía , Laminoplastia/tendencias , Osificación del Ligamento Longitudinal Posterior/cirugía , Satisfacción del Paciente , Complicaciones Posoperatorias/etiología , Anciano , Vértebras Cervicales/diagnóstico por imagen , Estudios de Cohortes , Femenino , Estudios de Seguimiento , Humanos , Laminoplastia/efectos adversos , Masculino , Persona de Mediana Edad , Osificación del Ligamento Longitudinal Posterior/diagnóstico por imagen , Complicaciones Posoperatorias/diagnóstico por imagen , Estudios Retrospectivos , Resultado del Tratamiento
17.
Aust Crit Care ; 32(3): 193-198, 2019 05.
Artículo en Inglés | MEDLINE | ID: mdl-30001953

RESUMEN

OBJECTIVE: In this study, we characterised the use of physical restraints in three intensive care units (ICUs) in a general hospital in Nantong, China. Additionally, we explored risk factors potentially related to physical restraint use. BACKGROUND: Despite their numerous harmful effects, physical restraints are frequently used in ICUs worldwide. Few studies have investigated the factors that contribute to physical restraint use in Chinese hospitals. METHODS: We conducted a prospective, cross-sectional, observational study of 312 patients in three ICUs at a general hospital in China. The quantitative data were collected during a 5-month period using a physical restraint observation form and patient records. The data obtained were analysed using descriptive statistics. The independent risk factors for physical restraint use were assessed using a logistic regression model. RESULTS: Of the 312 patients in the three ICUs, 191 (61.2%) were restrained, and physical restraints were used more than once for 46 (24.1%) patients during their ICU stay. The median length of physical restrain use was 20 shifts (interquartile range = 10-36 shifts). Physical restraints were applied in 6664 of 12374 (53.9%) nurse shifts. The most common time at which physical restraints were applied was the beginning of the evening shift. According to the forward stepwise logistic regression analysis, delirium (P < 0.001), mechanical ventilation (P < 0.001), and age (P < 0.001) were independent risk factors for physical restraint use. The use of analgesics (P = 0.001) exerted an independent protective effect against physical restraint use. CONCLUSIONS: The overall prevalence of physical restraint use in Chinese ICUs was higher than that reported in previous investigations. The patients' nursing notes lacked complete physical restraint records, reflecting a need for standard guidelines and policies for physical restraint use in hospital ICUs in China. In addition, in this study, we explored the risk factors related to physical restraint use and found that age, delirium, mechanical ventilation, and analgesic use are associated with physical restraint use.


Asunto(s)
Unidades de Cuidados Intensivos/estadística & datos numéricos , Restricción Física/estadística & datos numéricos , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , China , Estudios Transversales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Factores de Riesgo
18.
Psychogeriatrics ; 18(5): 412-420, 2018 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-29761589

RESUMEN

BACKGROUND: China is an ageing society, with around 150 million people aged 60 years or older. The prevalence of dementia will increase by more than 100% in the coming 20 years. This study aimed to investigate the prevalence and effects of dementia among the community elderly in Chongqing, China. METHODS: Cluster sampling was adopted. A sample of elderly individuals aged 60 years and older was extracted as research subjects from three counties within Chongqing, China. One-on-one interviews were conducted through a general information questionnaire, and the Mini-Mental State Examination, Instrumental Activity of Daily Living Scale, and Geriatric Depression Scale were administered. The investigated data were tested by χ2 , and the effect factors of dementia were analyzed by multiple logistic regression analysis. Statistical significance was set at P < 0.05. RESULTS: We distributed 1850 questionnaire, and the response rate was 100%. However, only 1781 questionnaires were able to be used in the study. Of the 1781 elderly respondents, 186 (10.44%) presented with dementia. Our findings revealed that differences in regions, age, marital status, education level, occupation, tobacco consumption, alcohol consumption, freshwater fish consumption, exercise, intensive labour, mah-jong- and chess-playing habits, media consumption (i.e. watching TV, listening to the radio, or reading the newspaper), body mass index, hypertension, coronary heart disease, and depression were statistically significant in the prevalence of dementia (P < 0.05). CONCLUSIONS: According to multiple logistic regression analyses, living in a rural area, older age, being single, obesity, hypertension, coronary heart disease, and depression are risk factors for dementia. In contrast, cessation of smoking, freshwater fish consumption, moderate or frequent exercise, intensive labour, daily housework, outdoor activities, media consumption, and social activities are protective factors against dementia among community elderly in Chongqing, China.


Asunto(s)
Demencia/epidemiología , Estilo de Vida , Salud Rural , Población Rural/estadística & datos numéricos , Factores de Edad , Anciano , Anciano de 80 o más Años , Consumo de Bebidas Alcohólicas/epidemiología , China/epidemiología , Demencia/diagnóstico , Depresión/epidemiología , Depresión/psicología , Femenino , Humanos , Masculino , Tamizaje Masivo , Síndrome Metabólico/epidemiología , Persona de Mediana Edad , Prevalencia , Escalas de Valoración Psiquiátrica , Factores de Riesgo , Factores Socioeconómicos
19.
Hua Xi Kou Qiang Yi Xue Za Zhi ; 35(1): 93-98, 2017 Feb 01.
Artículo en Chino | MEDLINE | ID: mdl-28326735

RESUMEN

Digital technology is a new trend in implant dentistry and oral medical technology. Stereolithographic surgical guides, which are computer-guided implant placement, have been introduced gradually to the market. Surgeons are attracted to this approach because of it features visualized preoperative planning, simple surgical procedure, flapless implant, and immediate restoration. However, surgeons are concerned about the accuracy and complications of this approach. This review aims to introduce the classification of computer-guided implant placement. The advantages, disadvantages, and accuracy of this approach are also analyzed. Moreover, factors that may affect the outcomes of computer-guided implant placement are determined. Results will provide a reference to surgeons regarding the clinical application of this approach.


Asunto(s)
Implantación Dental Endoósea , Cirugía Asistida por Computador , Planificación de Atención al Paciente
20.
Artículo en Chino | WPRIM (Pacífico Occidental) | ID: wpr-309069

RESUMEN

Digital technology is a new trend in implant dentistry and oral medical technology. Stereolithographic surgical guides, which are computer-guided implant placement, have been introduced gradually to the market. Surgeons are attracted to this approach because of it features visualized preoperative planning, simple surgical procedure, flapless implant, and immediate restoration. However, surgeons are concerned about the accuracy and complications of this approach. This review aims to introduce the classification of computer-guided implant placement. The advantages, disadvantages, and accuracy of this approach are also analyzed. Moreover, factors that may affect the outcomes of computer-guided implant placement are determined. Results will provide a reference to surgeons regarding the clinical application of this approach.


Asunto(s)
Implantación Dental Endoósea , Planificación de Atención al Paciente , Cirugía Asistida por Computador
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