RESUMEN

Since the official release as a KNIME Community Contribution in June 2013, the Vernalis KNIME nodes have increased from a single node (the 'PDB Connector' node) to around 126 nodes (November 2017; Version 1.12.0); furthermore, a number of nodes have been adopted into the core KNIME product. In this review, we provide a brief timeline of the development of the current public release and an overview of the current nodes. We will focus in more detail on three particular areas: nodes accessing publicly available information via web services, nodes providing cheminformatics functionality without recourse to a cheminformatics toolkit, and nodes using one of the cheminformatics toolkits present in KNIME. We will conclude with a number of case studies demonstrating the use of KNIME at Vernalis.

Asunto(s)

Quimioinformática , Programas Informáticos

RESUMEN

Positive future expectations can facilitate optimal development and contribute to healthier outcomes for youth. Researchers suggest that internal resources and community-level factors may influence adolescent future expectations, yet little is known about the processes through which these benefits are conferred. The present study examined the relationship between contribution to community, neighborhood collective efficacy, purpose, hope and future expectations, and tested a mediation model that linked contribution to community and collective efficacy with future expectations through purpose and hope in a sample of 7th grade youth (N = 196; Mage = 12.39; 60 % female; 40 % African American; 71 % economically disadvantaged). Greater collective efficacy and contribution to community predicted higher levels of hope and purpose. Higher levels of hope and purpose predicted more positive future expectations. Contribution to community and neighborhood collective efficacy indirectly predicted future expectations via hope. Implications of the findings and suggestions for future research are discussed.

Asunto(s)

Conducta del Adolescente/psicología , Satisfacción Personal , Autoeficacia , Cambio Social , Adolescente , Negro o Afroamericano , Niño , Femenino , Esperanza , Humanos , Relaciones Interpersonales , Masculino , Medio Oeste de Estados Unidos , Pobreza , Psicología del Adolescente , Instituciones Académicas , Estudiantes , Encuestas y Cuestionarios

RESUMEN

This article discusses the results of a study done in England that examined the activity involvement of people >60 years of age. Data were gathered through surveying two local newspapers, face- to face contacts, telephone calls, and letters. Areas examined included health and community welfare, education, politics, legal matters, religious affairs, businesses, environmental issues, and creative activity. Results found that many of the community's older people are productively occupied in these various areas. Positive and negative influences on their involvement are discussed, us well as ways of increasing older people's involvement in the future.