RESUMEN

Hip dysplasia is a common orthopaedic condition in dogs and stress radiography is the best diagnostic tool for early diagnosis. Objective force guidelines are lacking, leaving room for errors and fraud during screening. Our objective was to develop an accurate and validated measuring device that allows quantification of the applied force in vivo in real-time during stress radiographic imaging. A two-step approach was followed. First, four load cells were incorporated in the original Vezzoni Modified Badertscher Distension Device (VMBDD) and a dedicated computer program was developed. In vitro evaluations of the accuracy demonstrated a trueness of 0.19 N (0.1%FS) and precision of 0.26 N (0.2%FS) for the individual loadcells. The trueness and precision of the assembled VMBDmD were 0.02 N (0.02%FS) and 0.52 N (0.38%FS). Secondly, the modified device was tested on several cadavers. The device was similar in use as the VMBDD, did not interfere with radiographic acquisition, gave the operator real-time feedback, and linked the force with the radiograph. Altogether, we describe the accuracy of the VMBDmD and have evaluated its use in cadavers. We saw that the device successfully quantified and stored the applied force in real-time during stress radiography.

Asunto(s)

RESUMEN

Korean army dogs are raised for special purposes and have contributed much to society. However, several diseases occur in dogs. Canine hip dysplasia (CHD) is a musculoskeletal disorder that occurs frequently in Korean army dogs and interferes with their activities. If we could control CHD, this would have a positive effect on their performance. This study performed a genome-wide association study (GWAS) in 69 Korean army dogs to find significant loci for CHD using 170K single nucleotide polymorphisms (SNPs). CHD was classified according to the Norberg angle criterion. The control group comprised 62 dogs classified as relatively normal, and 7 dogs with severe CHD formed the case group. From the GWAS analysis, we concluded that SNPs present on chromosome 4 might have a significant impact on the overall expression of canine hip dysplasia.