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1.
J Pers Med ; 14(8)2024 Jul 25.
Artículo en Inglés | MEDLINE | ID: mdl-39201980

RESUMEN

(1) Background: Burn injuries in children present a significant public health concern due to their potential for severe physical and psychological impact. (2) Methods: This study investigates the determinants of pediatric burn severity by analyzing the interplay of demographic and environmental factors. Through a retrospective analysis of pediatric burn cases over five years, encompassing patient demographics, burn causative agents, and clinical outcomes, this research aims to identify significant predictors of burn severity. (3) Results: This study presents a comprehensive analysis of pediatric burn injuries, focusing on the severity, clinical outcomes, and multifactorial aspects influencing recovery. We reviewed 1498 pediatric burn cases from January 2015 to December 2020. The mean age of patients was 5.8 years, with a slight male predominance (54%). Scalds (45%), flame burns (30%), and contact burns (15%) were the most common burn types. Our findings indicate significant differences in burn severity based on TBSA, with 32.5% of cases having TBSA greater than 20%. Multivariate logistic regression identified rural residence, male gender, flame burns, and lower socioeconomic status as significant predictors of severe burn outcomes. The overall mortality rate was 2.5%, with higher rates among patients with TBSA greater than 40%. These results highlight the need for targeted prevention strategies and improved access to specialized burn care. (4) Conclusions: Understanding these factors can inform targeted prevention strategies and improve treatment protocols.

2.
Front Public Health ; 12: 1413986, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38989128

RESUMEN

Background: Burns are a prevalent form of unintentional injury and a significant public health concern in developing countries. We aimed to investigate the epidemiological and clinical characteristics of adult burn patients at a major center in Eastern China. Methods: This 6-year retrospective study analyzed patients with varying degrees of burns between January 2017 and December 2022 at the Suzhou Burns and Trauma Center. The study extracted demographic, clinical, and epidemiological data from electronic medical records for analysis. Results: The study included 3,258 adult patients, of which 64.3% were male. The largest age group affected 30-59-year-old adults (63.04%). Scalds were the leading cause of burns (1,346, 41.31%), followed by flames (1,271, 39.01%). The majority of burn hospitalizations were those with moderate burns (1791, 54.97%). The morbidity rate was low at 0.68%, while mortality was strongly associated with age, etiology, and total body surface area. Patients with certain types of burns, such as explosions, hot crush injuries, and electric burns had more operations, longer lengths of hospital stay, and higher costs compared to those with scalds and flame injuries. Conclusion: Different prevention strategies should be formulated according to different etiologies, ages, and genders.


Asunto(s)
Unidades de Quemados , Quemaduras , Humanos , Masculino , Estudios Retrospectivos , Quemaduras/epidemiología , China/epidemiología , Adulto , Femenino , Persona de Mediana Edad , Unidades de Quemados/estadística & datos numéricos , Anciano , Adulto Joven , Hospitalización/estadística & datos numéricos , Adolescente , Tiempo de Internación/estadística & datos numéricos
3.
J Plast Reconstr Aesthet Surg ; 94: 160-168, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38805847

RESUMEN

BACKGROUND: The Abbreviated Burn Severity Index (ABSI) is a five-variable scale to help evaluate burn severity upon initial assessment. As other studies have been conducted with comparatively small patient populations, the purpose of this study is to revalidate the prognostic relevance of the ABSI in our selected population (N = 1193) 4 decades after its introduction, considering the progress in the treatment of severe burn injuries over the past decades. In addition, we evaluate whether comorbidities influence the survival probability of severely burned patients. METHODS: This retrospective study presents data from the Center for Severely Burned Patients of the General Hospital in Vienna. We included 1193 patients for over 20 years. Regression models were used to describe the prognostic accuracy of the ABSI. RESULTS: The ABSI can still be used as a prognostic factor for the probability of survival of severely burned patients. The odds of passing increases by a factor of 2.059 for each unit increase in the ABSI with an area under the curve value of 0.909. Over time, the likelihood of survival increased. The existence of chronic kidney disease negatively impacts the survival probability of severely burned patients. CONCLUSION: The ABSI can still be used to provide accurate information about the chances of survival of severely burned patients; however, further exploration of the impact of chronic kidney disease on the survival probability and adding variables to the ABSI scale should be considered. The probability of survival has increased over the last 20 years.


Asunto(s)
Quemaduras , Humanos , Quemaduras/terapia , Quemaduras/mortalidad , Austria/epidemiología , Estudios Retrospectivos , Pronóstico , Masculino , Femenino , Persona de Mediana Edad , Adulto , Anciano , Índices de Gravedad del Trauma , Adulto Joven , Adolescente
4.
Sensors (Basel) ; 24(7)2024 Apr 03.
Artículo en Inglés | MEDLINE | ID: mdl-38610493

RESUMEN

Wildfires are pivotal to the functioning of many ecosystems globally, including the magnitude of surface erosion rates. This study aims to investigate the relationships between surface erosion rates and wildfire intensity in the tropical north savanna of Australia. The occurrence of fires in western Arnhem Land, Northern Territory, Australia was determined with remotely sensed digital datasets as well as analogue erosion measurement methods. Analysis was performed using satellite imagery to quantify burn severity via a monthly delta normalised burn ratio (dNBR). This was compared and correlated against on-ground erosion measurements (erosion pins) for 13 years. The dNBR for each year (up to +0.4) displayed no relationship with subsequent erosion (up to ±4 mm of erosion/deposition per year). Poor correlation was attributed to low fire severity, patchy burning, significant time between fires and erosion-inducing rainfall. Other influences included surface roughness from disturbances from feral pigs and cyclone impacts. The findings here oppose many other studies that have found that fires increase surface erosion. This accentuates the unique ecosystem characteristics and fire regime properties found in the tropical Northern Territory. Scenarios of late dry season fires with high severity were not observed in this study and require more investigations. Ecosystems such as the one examined here require specialised management practices acknowledging the specific ecosystem functions and processes. The methods employed here combine both analogue and digital sensors to improve understandings of a unique environmental system.

5.
Sci Total Environ ; 931: 172746, 2024 Jun 25.
Artículo en Inglés | MEDLINE | ID: mdl-38679103

RESUMEN

Temperate heathlands and blanket bogs are globally rare and face growing wildfire threats. Ecosystem impacts differ between low and high severity fires, where severity reflects immediate fuel consumption. This study assessed factors influencing fire severity in Scottish heathlands and blanket bogs, including the efficacy of the Canadian Fire Weather Index System (CFWIS). Using remote sensing, we measured the differenced Normalised Burn Ratio at 92 wildfire sites from 2015 to 2021. We used Generalised Additive Mixed Models to investigate the impact of topography, habitat wetness, CFWIS components and 30-day weather on severity. Dry heath exhibited higher severity than wet heath and blanket bog, and slope, elevation and south facing aspect were positively correlated to severity. Weather effects were less clear due to data scale differences, yet still indicated weather's significant role in severity. Rainfall had an increasingly negative effect from approximately 15 days before the fire, whilst temperature had an increasingly positive effect. Vapour Pressure Deficit (VPD) was the weather variable with highest explanatory value, and predicted severity better than any CFWIS component. The best-explained fire severity model (R2 = 0.25) incorporated topography, habitat wetness wind and VPD on the day of the fire. The Drought Code (DC), predicting organic matter flammability at ≥10 cm soil depth, was the CFWIS component with the highest predictive effect across habitats. Our findings suggest that wildfires in wet heath and blanket bogs are typically characterised by low severity, but that warmer, drier weather may increase the risk of severe, smouldering fires which threaten peatland carbon stores.


Asunto(s)
Ecosistema , Monitoreo del Ambiente , Incendios Forestales , Escocia , Humedales , Tiempo (Meteorología)
6.
Burns ; 50(6): 1662-1670, 2024 08.
Artículo en Inglés | MEDLINE | ID: mdl-38637258

RESUMEN

OBJECTIVES: The aim of this study was to investigate the moderating role of gender in the relationship between burn severity, perceived stigmatization and depressive symptoms at multiple time points postburn. MATERIALS AND METHODS: This multi-center study included data from two cohorts. Cohort 1 consisted of 215 burn survivors, participating in a longitudinal study with measures at 3 and 12 months postburn. Cohort 2 consisted of 180 burn survivors cross-sectionally assessed at 5 - 7 years postburn. Both cohorts completed self-reported measures of perceived stigmatization and depressive symptoms. The number of acute surgeries (i.e., no surgery, 1 surgery or 2 or more surgeries) was used as indicator of burn severity. Relations between number of surgeries, depressive symptoms, and perceived stigmatization, including possible indirect effects, were evaluated with gender-specific path models. RESULTS: In both men and women, number of surgical operations was related to higher levels of depressive symptoms and perceived stigmatization at 3 months after burn. In women, number of operations was still directly related to both constructs at 12 months after burn, which was cross-sectionally confirmed in the 5-7 years after burn cohort. In men, from 3 to 12 months after burn, depressive symptoms and perceived stigmatization were bidirectionally related, and, through these effects, number of surgeries was indirectly related to both outcomes. In the cross-sectional 5-7 years after burn cohort, number of operations was related to stigma but not to depressive symptoms of men. CONCLUSION: Number of operations had a different effect on psychosocial adaptation of male and female burn survivors. In women, a persistent direct link from number of operations to both depressive symptoms and perceived stigmatization was found over time. In men, the effect of number of operations was most evident in the short-term, after which perceived stigmatization and depressive symptoms became interrelated. This indicates that burn severity remains a factor of significance in psychological adjustment in women, whereas in men, this significance seems to decrease over time.


Asunto(s)
Quemaduras , Depresión , Estereotipo , Humanos , Quemaduras/psicología , Quemaduras/cirugía , Femenino , Masculino , Depresión/psicología , Adulto , Factores Sexuales , Persona de Mediana Edad , Estudios Transversales , Estudios Longitudinales , Sobrevivientes/psicología , Estigma Social , Adulto Joven , Anciano , Procedimientos Quirúrgicos Operativos/psicología
7.
Int J Appl Basic Med Res ; 14(1): 7-11, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38504838

RESUMEN

Background: Burns is one of the leading causes of mortality in developing countries like India. Most of the major burns requiring hospital care are not triaged adequately for the use of medical resources. An efficient mortality predicting scale would not only help in better care to those who will benefit the most but also make it easy to explain to patient's attendants. Among the various tools, revised Baux (rBaux) and modified Abbreviated Burn Severity Index (ABSI) are two most commonly used scales in developed nations. We proposed this study to analyze the reliability of these two scoring scales in our burn population. Aim: This study aimed to retrospectively study the two scoring systems and analyze them for their reliability in predicting mortality compared to actual observed mortality in each case. Materials and Methods: This study was conducted on all burn patients admitted to the intensive care unit of our hospital. Data on their demographic profile, total burn surface area, thickness of burns, inhalational injury, and other comorbidities were collected from files. rBaux and modified ABSI (mABSI) were calculated. The end result in the form of survival or nonsurvival was also recorded. Appropriate statistical analysis using Mann-Whitney U-test, Chi-square test, and receiver operator characteristic curve was done to look for a better scoring system out of the two. Results: A total of 504 patients were included in the study, out of which 337 were survivors. Female gender was not a risk factor for mortality in our study. The median rBaux score in the survivor group was 100 (80-110) and in nonsurvivor group was 111 (103-123). The median mABSI score in the survivor group was 8 (7-9) and in nonsurvivor group was 10 (9-11). The area under the receiver operating characteristic curve shows mABSI having better specificity for predicting mortality. rBAUX, though more sensitive, overestimates mortality than actual observed mortality. Conclusion: mABSI predicts mortality better than rBaux. A multicentric prospective study is recommended for mABSI to be used as a standard mortality predictor in burns in India.

8.
J Biomed Opt ; 29(2): 020901, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38361506

RESUMEN

Significance: Over the past decade, machine learning (ML) algorithms have rapidly become much more widespread for numerous biomedical applications, including the diagnosis and categorization of disease and injury. Aim: Here, we seek to characterize the recent growth of ML techniques that use imaging data to classify burn wound severity and report on the accuracies of different approaches. Approach: To this end, we present a comprehensive literature review of preclinical and clinical studies using ML techniques to classify the severity of burn wounds. Results: The majority of these reports used digital color photographs as input data to the classification algorithms, but recently there has been an increasing prevalence of the use of ML approaches using input data from more advanced optical imaging modalities (e.g., multispectral and hyperspectral imaging, optical coherence tomography), in addition to multimodal techniques. The classification accuracy of the different methods is reported; it typically ranges from ∼70% to 90% relative to the current gold standard of clinical judgment. Conclusions: The field would benefit from systematic analysis of the effects of different input data modalities, training/testing sets, and ML classifiers on the reported accuracy. Despite this current limitation, ML-based algorithms show significant promise for assisting in objectively classifying burn wound severity.


Asunto(s)
Quemaduras , Piel , Humanos , Imagen Óptica/métodos , Aprendizaje Automático , Algoritmos , Quemaduras/diagnóstico por imagen
9.
J Environ Manage ; 351: 119733, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38061103

RESUMEN

Understanding the landscape patterns of burn severity is vital for managing fire-prone ecosystems. Relatively limited research has been done about fire and burn severity patterns in subtropical forests. Here, we derived the pre-fire forest type data from a global land-cover product at 30 m resolution based on time-series Landsat imageries. Using Landsat 8 OLI remote sensing imagery and field-based composite burn index (CBI), this study spatially mapped the burn severity of 27 forest fires in the subtropical forest ecosystems in southern China from 2017 to 2021. The landscape pattern of patches with different burn severity was quantified using landscape indices. In addition, factors influencing the patterns of burn severity across the landscape were determined using the Geodetector model. Burn severity of patches varied significantly over space. High burn severity was common in forest patches with low fragmentation, low patch density, and regular shape. In contrast, moderate and low burn severity was prevalent in patches with smaller patch size, high patch density, and complex shapes. Extensively burned forest patches were located at higher elevations, while more fragmented patches were located in gently sloping areas. Topographic factors were the most significant factors influencing variances in burn severity across the forest patches, followed by weather conditions. Compared to low elevation areas, vegetation types at the high elevation areas (dominated by Masson pine) are more singular, with higher fuel loads, thus resulting in a more regularly-shaped distribution of highly severe burning patches. A detailed understanding of burn severity patterns and driving factors in a landscape can help develop sustainable forest management and restoration strategies. Practically, fire managers should conduct mechanical fuel treatments or thinning of forests at high-elevation areas to reduce the potential of severe fire behavior and the continuity of fire spread.


Asunto(s)
Incendios , China , Ecosistema , Bosques , Tiempo (Meteorología)
10.
Ecol Evol ; 13(12): e10761, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38107425

RESUMEN

Many fire-prone forests are experiencing wildfires that burn outside the historical range of variation in extent and severity. These fires impact pollinators and the ecosystem services they provide, but how the effects of fire are mediated by burn severity in different habitats is not well understood. We used generalized linear mixed models in a Bayesian framework to model the abundance of pollinators as a function of burn severity, habitat, and floral resources in post-fire, mid-elevation, conifer forest, and meadow in the Sierra Nevada, California. Although most species-level effects were not significant, we found highly consistent negative impacts of burn severity in meadows where pollinators were most abundant, with only hummingbirds and some butterfly families responding positively to burn severity in meadows. Moderate-severity fire tended to increase the abundance of most pollinator taxa in upland forest habitat, indicating that even in large fires that burn primarily at high- and moderate-severity patches may be associated with improved habitat conditions for pollinator species in upland forest. Nearly all pollinator taxa responded positively to floral richness but not necessarily to floral abundance. Given that much of the Sierra Nevada is predicted to burn at high severity, limiting high-severity effects in meadow and upland habitats may help conserve pollinator communities whereas low- to moderate-severity fire may be needed in both systems.

11.
Sci Total Environ ; 899: 165719, 2023 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-37482359

RESUMEN

Wildfires alter the structure and functioning of ecosystems through changes in their biotic and abiotic components. A deeper understanding recovery process concerning diverse communities and properties within these components can provide valuable insights into the ecological effects of wildfires. Therefore, it is appropriate to enhance our understanding of the resilience of bacterial communities after wildfires within Mediterranean ecosystems. In this research, soil bacterial community resilience was evaluated in three types of ecosystems for two fire severities, two years after a large wildfire in Mediterranean ecosystems. The resilience of the soil bacterial community refers to its ability to return to original state after disturbance. This capacity can be estimated by the study of its recovery over time. In this study we evaluated the resilience using the variables: alpha diversity, beta diversity and the changes in abundance of both OTUs (Operational Taxonomic Units) and principal bacterial taxa (phyla, classes or orders). Our results showed that resilience depends on fire severity and type of ecosystem. We studied three ecosystems with different stage in the secondary succession: low maturity shrublands and heathlands, and high maturity oak forests. In general, high resilience in the soil bacterial community was observed in heathlands under low and high fire severity conditions. The other two ecosystems were resilient only under low fire severity. Stochastic replacement of the abundance of the OTUs was observed in all three ecosystems, with a notable impact on oak forests, under during high-severity conditions.


Asunto(s)
Ecosistema , Incendios Forestales , Suelo/química , Bosques , Bacterias
12.
Sci Total Environ ; 893: 164832, 2023 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-37321501

RESUMEN

In the United States (US), forest ecosystems are the largest terrestrial carbon sink, offsetting the equivalent of >12 % of economy-wide greenhouse gas (GHG) emissions annually. In the Western US, wildfires have shaped much of the landscape by changing forest structure and composition, increasing tree mortality, impacting forest regeneration, and influencing forest carbon storage and sequestration capacity. Here, we used remeasurements of >25,000 plots from the US Department of Agriculture, Forest Service Forest Inventory and Analysis (FIA) program and auxiliary information (e.g., Monitoring Trends in Burn Severity) to characterize the role of fire along with other natural and anthropogenic drivers on estimates of carbon stocks, stock changes, and sequestration capacity on forest land in the Western US. Several biotic (e.g., tree size, species, and forest structure) and abiotic factors (e.g., warm climate, severe drought, compound disturbances, and anthropogenic interventions) influenced post-fire tree mortality and regeneration and had concomitant impacts on carbon stocks and sequestration capacity. Forest ecosystems in a high severity and low frequency wildfire regime had greater reductions in aboveground biomass carbon stocks and sequestration capacity compared to forests in a low severity and high frequency fire regime. Results from this study can improve our understanding of the role of wildfire along with other biotic and abiotic drivers on carbon dynamics in forest ecosystems in the Western US.


Asunto(s)
Incendios , Incendios Forestales , Estados Unidos , Ecosistema , Carbono/análisis , Secuestro de Carbono
13.
Sci Total Environ ; 894: 165000, 2023 Oct 10.
Artículo en Inglés | MEDLINE | ID: mdl-37343882

RESUMEN

Due to complex interactions between climate and land use changes, large forest fires have increased in frequency and severity over the last decades, impacting dramatically on biodiversity and society. In southern European countries affected by demographic challenges, fire risk and danger play special relevance at the wildland-urban interfaces (WUIs), where decision-making and land management have strong socio-ecological implications. WUIs have been historically typified according to both fire occurrence probability and settlement vulnerability, but those classifications lack generality regarding fire regime components. We aim to develop an integrated and comprehensive scheme for identifying the WUI typologies most at risk to fire severity across large territories. We selected fourteen large wildfires (over than 500 ha) occurred in Spain (2016-2021) containing different WUI scenarios. First, based on a building cartography and a multi-temporal series of Sentinel-2 imagery, each WUI was delimited and spatially characterized according to building density and pre-fire fuel characteristics (type, amount, and structure). Afterwards, a decision tree regression model was applied to identify the most relevant pre-fire vegetation parameters driving burn severity. The combined effect of the selected pre-fire vegetation drivers and the building density patterns on fire severity was evaluated using linear mixed models. Finally, the WUI typologies most prone to high burn severity were recognized using Tukey post-hoc tests. Results indicated that building density, land cover class and vegetation cover fraction determined fire severity in areas close to human settlements. Specifically, isolated, scattered and sparsely clustered buildings enclosed in a high-cover shrub matrix were the WUI typologies most susceptible to high-severity fires. These findings contribute to the development of appropriate strategies to minimize the risk of severe fires in WUIs and avoid potential losses of multiple ecosystem services valuable for society.

14.
Environ Res ; 233: 116510, 2023 09 15.
Artículo en Inglés | MEDLINE | ID: mdl-37385415

RESUMEN

Fire regimes in mountain landscapes of southern Europe have been shifting from their baselines due to rural abandonment and fire exclusion policies. Understanding the effects of fire on biodiversity is paramount to implement adequate management. Herein, we evaluated the relative role of burn severity and heterogeneity on bird abundance in an abandoned mountain range located in the biogeographic transition between the Eurosiberian and Mediterranean region (the Natural Park 'Baixa Limia-Serra do Xurés'). We surveyed the bird community in 206 census plots distributed across the Natural Park, both inside and outside areas affected by wildfires over the last 11 years (from 2010 to 2020). We used satellite images of Sentinel 2 and Landsat missions to quantify the burn severity and heterogeneity of each fire within each surveyed plot. We also accounted for the past land use (forestry or agropastoral use) by using a land cover information for year 2010 derived from satellite image classification. We recorded 1735 contacts from 28 bird species. Our models, fitted by using GLMs with Poisson error distribution (pseudo-R2-average of 0.22 ± 0.13), showed that up to 71% of the modeled species were linearly correlated with at least one attribute of the fire regime. The spatiotemporal variation in burnt area and severity were relevant factors for explaining the local abundance of our target species (39% of the species; Akaike weights >0.75). We also found a quadratic effect of at least one fire regime attribute on bird abundance for 60% of the modeled species. The past land use, and its legacy after 10 years, was critical to understand the role of fire (Akaike weights >0.75). Our findings confirm the importance of incorporating remotely sensed indicators of burn severity into the toolkit of decision makers to accurately anticipate the response of birds to fire management.


Asunto(s)
Quemaduras , Incendios , Incendios Forestales , Animales , Bosques , Aves/fisiología , Ecosistema
15.
Ecology ; 104(6): e4042, 2023 06.
Artículo en Inglés | MEDLINE | ID: mdl-36976178

RESUMEN

As 21st-century climate and disturbance dynamics depart from historic baselines, ecosystem resilience is uncertain. Multiple drivers are changing simultaneously, and interactions among drivers could amplify ecosystem vulnerability to change. Subalpine forests in Greater Yellowstone (Northern Rocky Mountains, USA) were historically resilient to infrequent (100-300 year), severe fire. We sampled paired short-interval (<30-year) and long-interval (>125-year) post-fire plots most recently burned between 1988 and 2018 to address two questions: (1) How do short-interval fire, climate, topography, and distance to unburned live forest edge interact to affect post-fire forest regeneration? (2) How do forest biomass and fuels vary following short-interval versus long-interval severe fires? Mean post-fire live tree stem density was an order of magnitude lower following short-interval versus long-interval fires (3240 vs. 28,741 stems ha-1 , respectively). Differences between paired plots were amplified at longer distances to live forest edge. Surprisingly, warmer-drier climate was associated with higher seedling densities even after short-interval fire, likely relating to regional variation in serotiny of lodgepole pine (Pinus contorta var. latifolia). Unlike conifers, density of aspen (Populus tremuloides), a deciduous resprouter, increased with short-interval versus long-interval fires (mean 384 vs. 62 stems ha-1 , respectively). Live biomass and canopy fuels remained low nearly 30 years after short-interval fire, in contrast with rapid recovery after long-interval fire, suggesting that future burn severity may be reduced for several decades following reburns. Short-interval plots also had half as much dead woody biomass compared with long-interval plots (60 vs. 121 Mg ha-1 ), primarily due to the absence of large snags. Our results suggest differences in tree regeneration following short-interval versus long-interval fires will be especially pronounced where serotiny was high historically. Propagule limitation will also interact with short-interval fires to diminish tree regeneration but lessen subsequent burn severity. Amplifying driver interactions are likely to threaten forest resilience under expected trajectories of a future fire.


Asunto(s)
Quemaduras , Incendios , Pinus , Ecosistema , Bosques , Árboles
16.
Indian J Plast Surg ; 56(1): 39-43, 2023 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-36998930

RESUMEN

Background Several burn-specific mortality prediction models have been formulated and validated in the developed countries. There is a dearth of studies validating these models in the Indian population. Our objective was to validate three such models in the Indian burn patients. Methods A prospective observational study was performed after ethical clearance on consecutive eligible consenting burn patients. Patient demographics, vitals, and results of hematological workup were collected. Using these. the Abbreviated Burn Severity Index (ABSI), the revised Baux score (rBaux), and the Fatality by Longevity, APACHE II score, Measured extent of burn, and Sex score (FLAMES) were calculated. The discriminative ability of the ABSI, rBaux, and the FLAMES was tested using the receiver operating characteristic (ROC) curve at 30 days and the area under the ROC curve (AUROC) compared. A p -value ≤ 0.05 was considered significant. Probability of death was calculated using these models. Hosmer-Lemeshow goodness of fit test was run. Results The ABSI (AUROC 0.7497, 95% CI 0.67796-0.82141), rBaux (AUROC 0.7456, 95% CI 0.67059-0.82068) and FLAMES (AUROC 0.7119, 95% CI 0.63209-0.79172), had fair discriminative ability. The Hosmer-Lemeshow test reported that ABSI and rBaux were a good fit for the Indian population, while FLAMES was not a good fit. Conclusion The ABSI and rBaux had a fair discriminative ability and were a good fit for the adult patients with 30 to 60% thermal and scald burn patients. FLAMES despite having fair discriminative ability was not a good fit for the study population.

17.
Burns ; 49(4): 806-812, 2023 06.
Artículo en Inglés | MEDLINE | ID: mdl-35618514

RESUMEN

BACKGROUND: C-reactive protein (CRP) is an acute-phase protein produced in response to inflammation after traumatic injury. We posit that C-reactive protein (CRP) is reliable in predicting morbidity and mortality following severe burn. In this study, we explored the relationship between serum CRP values and clinical outcomes in the severely burned. METHODS: Using the Research Network within the TriNetX database, we queried de-identified burn patient data across the United States and enrolled 36,556 burn patients with reported CRP values from 2006 to 2020. RESULTS: Circulating CRP levels were elevated significantly in patients ≥60 years as well as in males and African Americans (p < 0.05). CRP levels reached the zenith on the first day after burn, and were highest when burn size reached 60% total body surface area (TBSA). After bisecting the data at 10 mg/L of CRP, we compared clinical findings between patient groups (n = 16,284/18,647 in high/low CRP levels). The risk of patient death doubled in the high CRP group from 4.687% to 9.313%, with higher incidences of sepsis, skin infection, and myocardial infarction (p < 0.05). Moreover, mortality increased from 0.9% to 1.926% in those younger than 20 years when comparing the low and high CRP groups, whereas mortality significantly increased from 8.84% to 15.818% in those ≥60 years old (p < 0.05). Both elderly and paediatric groups had significant increases in the diagnosis of sepsis-associated with increased CRP expression. However, incidences of skin infection, pneumonia, and acute kidney injury increased significantly only in the elderly group (p < 0.05). CONCLUSION: Elevated CRP expression is common in burn patients. The factor of age influenced the association of CRP expression to clinical outcomes.


Asunto(s)
Quemaduras , Sepsis , Masculino , Humanos , Niño , Anciano , Persona de Mediana Edad , Quemaduras/complicaciones , Proteína C-Reactiva/metabolismo , Inflamación , Sepsis/complicaciones , Morbilidad
18.
Ecology ; 104(3): e3968, 2023 03.
Artículo en Inglés | MEDLINE | ID: mdl-36571436

RESUMEN

A key challenge in ecology is understanding how multiple drivers interact to precipitate persistent vegetation state changes. These state changes may be both precipitated and maintained by disturbances, but predicting whether the state change will be fleeting or persistent requires an understanding of the mechanisms by which disturbance affects the alternative communities. In the sagebrush shrublands of the western United States, widespread annual grass invasion has increased fuel connectivity, which increases the size and spatial contiguity of fires, leading to postfire monocultures of introduced annual grasses (IAG). The novel grassland state can be persistent and is more likely to promote large fires than the shrubland it replaced. But the mechanisms by which prefire invasion and fire occurrence are linked to higher postfire flammability are not fully understood. A natural experiment to explore these interactions presented itself when we arrived in northern Nevada immediately after a 50,000 ha wildfire was extinguished. We hypothesized that the novel grassland state is maintained via a reinforcing feedback where higher fuel connectivity increases burn severity, which subsequently increases postfire IAG dispersal, seed survivorship, and fuel connectivity. We used a Bayesian joint species distribution model and structural equation model framework to assess the strength of the support for each element in this feedback pathway. We found that prefire fuel connectivity increased burn severity and that higher burn severity had mostly positive effects on the occurrence of IAG and another nonnative species and mostly negative or neutral relationships with all other species. Finally, we found that the abundance of IAG seeds in the seed bank immediately after a fire had a positive effect on the fuel connectivity 3 years after the fire, completing a positive feedback promoting IAG. These results demonstrate that the strength of the positive feedback is controlled by measurable characteristics of ecosystem structure, composition, and disturbance. Further, each node in the loop is affected independently by multiple global change drivers. It is possible that these characteristics can be modeled to predict threshold behavior and inform management actions to mitigate or slow the establishment of the grass-fire cycle, perhaps via targeted restoration applications or prefire fuel treatments.


Asunto(s)
Quemaduras , Incendios , Ecosistema , Supervivencia , Teorema de Bayes , Banco de Semillas , Poaceae
19.
Glob Chang Biol ; 29(6): 1648-1659, 2023 03.
Artículo en Inglés | MEDLINE | ID: mdl-36517954

RESUMEN

Area burned has decreased across Europe in recent decades. This trend may, however, reverse under ongoing climate change, particularly in areas not limited by fuel availability (i.e. temperate and boreal forests). Investigating a novel remote sensing dataset of 64,448 fire events that occurred across Europe between 1986 and 2020, we find a power-law relationship between maximum fire size and area burned, indicating that large fires contribute disproportionally to fire activity in Europe. We further show a robust positive correlation between summer vapor pressure deficit and both maximum fire size (R2  = .19) and maximum burn severity (R2  = .12). Europe's fire regimes are thus highly sensitive to changes in future climate, with the probability for extreme fires more than doubling by the end of the century. Our results suggest that climate change will challenge current fire management approaches and could undermine the ability of Europe's forests to provide ecosystem services to society.


Asunto(s)
Incendios , Incendios Forestales , Ecosistema , Bosques , Europa (Continente)
20.
Cureus ; 14(6): e26161, 2022 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-35891871

RESUMEN

Background Burn injuries are highly variable and dynamic. The outcome of patients is influenced by various factors and requires prompt therapeutic interventions, including fluid resuscitation, for a favorable result. Although having varying shortcomings, many scoring indexes are developed and validated in Western countries to predict mortality in a burn patient. The Abbreviated Burn Severity Index (ABSI) estimates survival expectancy in a burn patient via various negative prognostic factors. This study describes the pattern of burn injuries to validate the ABSI as an outcome predictor in burnt patients. Methodology From January to December 2018, 100 patients participated in this observational research conducted in the Department of Surgery at Mahatma Gandhi Hospital's Burn Ward, a part of Dr. Sampurnanand Medical College, Jodhpur. Risk factors for death from a burn were patients' age and gender, the depth of the burn, the inhalation burn, and the total burned body surface area (TBSA). The area under the receiver operating curve (AUROC) was used to determine how well it could predict burn deaths. Results This study included 100 patients (69 men and 31 women, with a ratio of 2.22:1). In total, 73 patients survived, and 27 died (a mortality rate of 27%). The fatality rate increased with increased burn surface area, reaching 100% in patients with >80% burns (p < 0.0001). Additionally, those with an ABSI of >11 expressed 100% mortality rate (p < 0.0001). Conclusions In this study, older age, high burned surface area, concomitant inhalational burns, full-thickness burns, and a higher ABSI were found to be significant predictors of mortality.

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