RESUMEN

The study describes the synthesis of new geminally disubstituted C-linked carbo-ß(2,2)-amino acids (ß(2,2)-Caas) with different carbohydrate side chains, and their use in the synthesis of ß(2,2)-peptides. The study infers that the side chain has an influence on the synthesis of peptides and their conformational behaviour.

Asunto(s)

Aminoácidos/síntesis química , Carbohidratos/química , Péptidos/síntesis química , Pliegue de Proteína , Estabilidad Proteica , Estructura Secundaria de Proteína , Estereoisomerismo