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1.
Case Rep Surg ; 2016: 1858461, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27872785

RESUMEN

Background. Splenic artery aneurysm (SAA) is an uncommon and difficult diagnosis. SAA is more common in females. Only 20% of SAA is symptomatic and may present as a rupture. A ruptured SAA is associated with a 25% mortality rate. Case Presentation. We present a case of a male patient with a bleeding SAA that rapidly increased in size. Distal coiling was technically impossible and despite proximal coil embolisation the SAA continued to bleed. A laparotomy including splenectomy and partial pancreatectomy was performed with an uneventful patient recovery. Discussion. Endovascular management is currently considered the optimal treatment of SAA. However, careful monitoring and follow-up is needed after embolisation as rapid recanalization of the SAA may possibly occur, especially when distal coiling of the aneurysm is unsuccessful. Conclusion. Endovascular treatment of an SAA is not necessarily effective. Surgeons must be prepared to perform open procedures to further reduce mortality rates.

2.
Eur J Endocrinol ; 151(6): 765-9, 2004 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-15588244

RESUMEN

We report a case of spinal epidural lipomatosis (SEL) caused by ectopic Cushing's syndrome and give a review of the literature. The most common cause of SEL is prolonged therapy with glucocorticoids, only a very few cases are related to endogenous Cushing's syndrome. The pathophysiological mechanism is not clear but there is a possible role for the autonomic nervous system in the stimulation of growth of epidural fat. Severe neurological symptoms which indicate myelopathy and radiculopathy can occur, but there is often a delay in diagnosis because the non-specific initial symptoms are not recognized. The epidural fat is mostly located in the thoracic and lumbar region. Magnetic resonance imaging can establish the diagnosis rapidly. In patients with severe neurological symptoms, surgical decompression of the myelum and removal of the epidural fat is the treatment of choice. Most patients have partial or complete recovery of neurological deficits after surgical treatment or after discontinuing glucocorticoid therapy; mild cases can also be treated conservatively. Routine imaging for the detection of epidural-located lipomatosis in patients at risk is probably useful.


Asunto(s)
Síndrome de Cushing/complicaciones , Espacio Epidural/metabolismo , Lipomatosis/etiología , Síndromes Paraneoplásicos Endocrinos/etiología , Enfermedades de la Columna Vertebral/etiología , Hormona Adrenocorticotrópica/metabolismo , Adulto , Síndrome de Cushing/patología , Espacio Epidural/patología , Humanos , Lipomatosis/patología , Imagen por Resonancia Magnética , Masculino , Síndromes Paraneoplásicos Endocrinos/patología , Receptores de Somatostatina/metabolismo , Enfermedades de la Columna Vertebral/patología , Columna Vertebral/patología
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