RESUMEN
CT-guided percutaneous needle biopsy of the spine is a well-described technique for determining the nature of indeterminate vertebral lesions or establishing a diagnosis of spinal infection, the high diagnostic accuracy and the safety of the procedure having been extensively documented. The purpose of the current article is to review the literature to date on CT-guided spinal biopsy. Specifically, indications for spinal biopsy, techniques for optimising yield, detail of the approaches for various spinal levels which is dependent upon both the region within the spinal column and lesion location within the vertebra (body vs. neural arch), determinants of biopsy outcome and complications are covered. It is hoped that the review will be of particular benefit to junior radiologists who are required to perform this procedure.
Asunto(s)
Biopsia Guiada por Imagen , Columna Vertebral , Biopsia con Aguja , Humanos , Agujas , Estudios Retrospectivos , Columna Vertebral/diagnóstico por imagen , Tomografía Computarizada por Rayos XRESUMEN
Hyperparathyroidism jaw tumour syndrome is a rare autosomal dominant inherited endocrine neoplasia syndrome, which predisposes carriers to develop a triad of multiple ossifying fibromas of the maxilla and mandible, parathyroid adenomas and carcinomas (with consequent hyperparathyroidism) as well as renal and uterine tumours. The prevalence of this condition is unknown. Patients typically present initially with symptoms and signs of a jaw tumour. A high index of suspicion is required for the underlying diagnosis to be recognised, enabling appropriate management of jaw lesions, treatment of hyperparathyroidism, if present, as well as early detection of malignant disease and screening of family members. TEACHING POINTS: ⢠HPT-JT is a rare autosomal dominant inherited endocrine neoplasia syndrome. ⢠HPT-JT causes facial disfigurement, morbidity secondary to hyperparathyroidism and malignancy. ⢠Patients can present with ossifying fibromas of the jaw, hypercalcaemia or malignancy. ⢠A high index of suspicion is required for the underlying diagnosis to be recognised. ⢠Management involves screening of family members.
RESUMEN
Rheumatological manifestations complicate many benign and malignant blood disorders. Significant advances in haematology, with improved diagnostic techniques and newer musculoskeletal imaging, have occurred in the past two decades. This review focuses on the interrelationship between the major haematological diseases (haemochromatosis, haemophilia, sickle cell disease, thalassaemia, leukaemia, lymphoma, myelodysplastic syndromes, multiple myeloma and cryoglobulinaemia) and rheumatic manifestations.