1.
Int J Immunogenet
; 38(6): 519-23, 2011 Dec.
Artículo
en Inglés
| MEDLINE
| ID: mdl-21902816
RESUMEN
Type 2 diabetes (T2D) is characterized by a chronic low-grade inflammatory state. SNP in Toll-like receptor (TLR) genes has been associated with impaired inflammatory response. We genotyped the TLR4/D299G, TLR4/T399I and TLR2/R753Q polymorphisms. Low frequency was found with no association with T2D, nevertheless the TLR2 SNP was associated with lower levels in HDL-cholesterol values.