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1.
Eur Arch Otorhinolaryngol ; 280(4): 1671-1676, 2023 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-36115871

RESUMEN

PURPOSE: Our objective is to evaluate the effect of habituation on the altered ear canal acoustics after canal wall down mastoidectomy. METHODS: A total of 11 participants with single sided dry cavities and normal contralateral ear canals with normal hearing thresholds were included in the study. Filtered sound fragments were created that simulate the different acoustic properties based on the participants Real Ear to Coupler Difference (RECD) of the cavity ear and the contralateral normal ear canal. These filtered sound fragments are presented to the cavity ear canal and the contralateral normal ear canal using inserts earphones. Participants performed a subjective quality assessment of the sound fragments using paired comparison with a seven-point scale (- 3 till + 3). RESULTS: Mean assessment of sound quality revealed the following results; naturalness of sounds of the cavity ear canal is 0.29 (± 1.41; ns) in favour of the filtered sound fragment of the normal ear canal. Mean assessment of sharpness of sounds in the cavity ear canal is 1.55 (± 1.21, p = 0.55) in favour of the filtered sound fragment of the normal ear canal. Overall preference in the cavity ear canal was in favour of the normal ear canal acoustics 0.72 (SD ± 1.54 p = 0.224). CONCLUSIONS: Patients with cavity ear canals seem to habituate to their altered ear canal acoustics. Transforming the ear canal acoustics of the cavity ear to normal ear canal acoustics seem to sharpen the incoming sounds. Overall assessment of quality of sound of the normal ear canal acoustics is better than the cavity acoustics.


Asunto(s)
Habituación Psicofisiológica , Mastoidectomía , Humanos , Acústica , Audición , Sonido , Conducto Auditivo Externo/cirugía
3.
J Laryngol Otol ; 135(5): 410-414, 2021 May.
Artículo en Inglés | MEDLINE | ID: mdl-33883045

RESUMEN

OBJECTIVE: This study aimed to compare the necessary scutum defect for transmeatal visualisation of middle-ear landmarks between an endoscopic and microscopic approach. METHOD: Human cadaveric heads were used. In group 1, middle-ear landmarks were visualised by endoscope (group 1 endoscopic approach) and subsequently by microscope (group 1 microscopic approach following endoscopy). In group 2, landmarks were visualised solely microscopically (group 2 microscopic approach). The amount of resected bone was evaluated via computed tomography scans. RESULTS: In the group 1 endoscopic approach, a median of 6.84 mm3 bone was resected. No statistically significant difference (Mann-Whitney U test, p = 0.163, U = 49.000) was found between the group 1 microscopic approach following endoscopy (median 17.84 mm3) and the group 2 microscopic approach (median 20.08 mm3), so these were combined. The difference between the group 1 endoscopic approach and the group 1 microscopic approach following endoscopy plus group 2 microscopic approach (median 18.16 mm3) was statistically significant (Mann-Whitney U test, p < 0.001, U = 18.000). CONCLUSION: This study showed that endoscopic transmeatal visualisation of middle-ear landmarks preserves more of the bony scutum than a microscopic transmeatal approach.


Asunto(s)
Oído Medio/diagnóstico por imagen , Oído Medio/cirugía , Endoscopía , Microcirugia , Procedimientos Quirúrgicos Otológicos , Cadáver , Humanos , Imagenología Tridimensional , Tomografía Computarizada por Rayos X
4.
Tijdschr Psychiatr ; 63(4): 283-286, 2021.
Artículo en Holandés | MEDLINE | ID: mdl-33913144

RESUMEN

BACKGROUND: In the last decade, regulations regarding the fitness to drive in The Netherlands have been changed extensively. AIM: To describe the changes in the regulations, and to evaluate the consequences for daily practice. METHOD: Overview of changes in the regulations concerning the fitness to drive as published in the Dutch legislation announcements in the past 10 years. RESULTS: Important changes have been implemented regarding the regulations on fitness to drive in patients with affective disorders, psychotic disorders, dementia, ADHD and pervasive developmental disorders. CONCLUSION: Compared to 2010, the regulations concerning the fitness to drive in psychiatric disorders are less rigid, more balanced, and more evidence based. Therefore, it has become easier to inform and advise the patient on this topic.


Asunto(s)
Conducción de Automóvil/legislación & jurisprudencia , Conducción de Automóvil/psicología , Trastornos Mentales/complicaciones , Accidentes de Tránsito/prevención & control , Guías como Asunto , Humanos , Competencia Mental , Trastornos Mentales/psicología , Países Bajos , Población Blanca
5.
J Laryngol Otol ; 134(5): 431-433, 2020 May.
Artículo en Inglés | MEDLINE | ID: mdl-32308165

RESUMEN

OBJECTIVE: This study aimed to assess whether increasing operative experience results in better surgical outcomes in endoscopic middle-ear surgery. METHODS: A retrospective single-institution cohort study was performed. Patients underwent endoscopic tympanoplasty between May 2013 and April 2019 performed by the senior surgeon or a trainee surgeon under direct supervision from the senior surgeon. Following data collection, statistical analysis compared success rates between early (learning curve) surgical procedures and later (experienced) tympanoplasties. RESULTS: In total, 157 patients (86 male, 71 female), with a mean age of 41.6 years, were included. The patients were followed up for an average of 43.2 weeks. The overall primary closure rate was 90.0 per cent. CONCLUSION: This study demonstrates an early learning curve for endoscopic ear surgery that improves with surgical experience. Adoption of the endoscopic technique did not impair the success rates of tympanoplasty.


Asunto(s)
Competencia Clínica/normas , Endoscopía/educación , Curva de Aprendizaje , Otolaringología/educación , Timpanoplastia/educación , Adulto , Endoscopía/normas , Endoscopía/estadística & datos numéricos , Femenino , Trastornos de la Audición/cirugía , Humanos , Masculino , Auditoría Médica , Otolaringología/normas , Estudios Retrospectivos , Resultado del Tratamiento , Timpanoplastia/normas , Timpanoplastia/estadística & datos numéricos
6.
Eur Arch Otorhinolaryngol ; 277(9): 2455-2462, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-32335711

RESUMEN

PURPOSE: To correlate the subjective quality assessment of ear canal acoustics of the participants to the objective measurement of the ear canal acoustics. The objective ear canal acoustics is the frequency-dependent modulation of soundwaves through the ear canal. Our second objective is to design a model to predict the subjective quality of sound based on the altered objective ear canal acoustics. METHODS: To determine the frequency-dependent modulation of the soundwaves the real-ear unaided gain (REUG) of the ear canal is measured. 40 participants with normal hearing were presented six simulated sound fragments representing the acoustic properties of six different ear canals (REUG). These six sound fragments were built based on the difference between these six REUGs and the average REUG of a normal adult ear canal. Subjective sound quality was evaluated using a VAS score and a paired comparison score. RESULTS: We found a strong correlation between the objective ear canal acoustics and the subjective assessment of the quality of sound (Spearman's rho-0.89). Our linear mixed VAS model for individual participants has an intercept of 95.6 and a slope of - 4.2 (p < 0.001). The paired comparison analysis endorsed our findings that an increased difference in REUG is predictive for a decreased quality assessment of ear canal acoustics. CONCLUSION: There is a strong correlation between the subjective evaluation of ear canal acoustics and the objective quality assessment of ear canal acoustics. Our models show that an increased difference in REUG predicts a decreased quality of ear canal acoustics.


Asunto(s)
Conducto Auditivo Externo , Procedimientos Quirúrgicos Otológicos , Acústica , Adulto , Pruebas Auditivas , Humanos , Sonido
8.
Health Qual Life Outcomes ; 17(1): 105, 2019 Jun 18.
Artículo en Inglés | MEDLINE | ID: mdl-31215443

RESUMEN

BACKGROUND: To validate and evaluate the reliability of the Dutch version of the Chronic Ear Survey (CES) in patients suffering from Chronic Suppurative Otitis Media (CSOM) and to evaluate clinical outcomes of surgery using this questionnaire. METHODS: We developed the Dutch version of the CES (D-CES) using forward-backward translation of the original CES into the Dutch language. Next, patients with CSOM and controls completed the D-CES pre- and postoperatively. Internal consistency, test-retest reliability, known-group validity and convergent validity were evaluated. In addition to the D-CES, the Short Form 36 (SF-36) was administered to all participants to correlate D-CES data to quality of life. RESULTS: A total of 29 patients with CSOM scheduled for ear surgery were included. Our control group consisted of 26 patients scheduled for eye surgery, all without signs and symptoms of CSOM. Cronbachs' α of the complete questionnaire was 0.69. The Intraclass Correlation Coefficients (ICCs), reflecting test-retest reliability, ranged between 0.69 and 0.82. Scores differed significantly between CSOM patients and controls with substantial lower (more impaired) D-CES scores in the CSOM group. Duration of complaints preoperatively and the presence of a dry ear and/or improvement of hearing postoperatively all had a significant impact on D-CES improvement scores. Small to moderate correlations were found between D-CES subscales and matching subscales of the SF-36. CONCLUSION: The D-CES is an appropriate disease specific questionnaire to assess a patient's perceived functional health in CSOM.


Asunto(s)
Otitis Media Supurativa/psicología , Calidad de Vida , Encuestas y Cuestionarios/normas , Adulto , Anciano , Anciano de 80 o más Años , Estudios de Casos y Controles , Femenino , Humanos , Masculino , Persona de Mediana Edad , Países Bajos , Otitis Media Supurativa/cirugía , Reproducibilidad de los Resultados , Traducciones , Adulto Joven
9.
Acta Anaesthesiol Scand ; 62(3): 328-335, 2018 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-29119549

RESUMEN

BACKGROUND: Ventilation through small-diameter tubes typically precludes use of a cuff as this will impede the necessary passive outflow of gas alongside the tube's outer surface. Ventrain assists expiration and enables oxygenation and normoventilation through small-bore cannulas or catheters, particularly in obstructed airways. A small-bore ventilation catheter (SBVC; 40 cm long, 2.2 mm inner diameter) with a separate pressure monitoring lumen and a cuff was developed. Efficacy of oxygenation and ventilation with Ventrain through this catheter was investigated in sealed and open airways in a porcine cross-over study. METHODS: Six pigs were ventilated with Ventrain (15 l/min oxygen, frequency 30 breaths per min, I : E-ratio 1 : 1) through the SBVC, both with the cuff inflated and deflated. Prior to each test they were ventilated conventionally until steady state was achieved. RESULTS: With an inflated cuff, PaO2 rose instantly and remained elevated (median [range] PaO2 61 [52-69] kPa after 30 min; P = 0.027 compared to baseline). PaCO2 remained stable at 4.9 [4.2-6.2] kPa. After cuff deflation, PaO2 was significantly lower (9 [5-28] kPa at 10 min, P = 0.028) and interventional ventilation had to be stopped prematurely in five pigs as PaCO2 exceeded 10.6 kPa. Pulmonary artery pressures increased markedly in these pigs. Intratracheal pressures were kept between 5 and 20 cmH2 O with the cuff inflated, but never exceeded 2 cmH2 O after cuff deflation. CONCLUSION: The SBVC combines the benefits of a small diameter airway and a cuff. Cuff inflation optimizes oxygenation and ventilation with Ventrain.


Asunto(s)
Catéteres , Respiración Artificial/instrumentación , Animales , Dióxido de Carbono/sangre , Femenino , Hemodinámica , Intubación Intratraqueal/instrumentación , Oxígeno/sangre , Presión , Porcinos
10.
Eur J Vasc Endovasc Surg ; 54(4): 495-503, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28778457

RESUMEN

OBJECTIVE/BACKGROUND: Deep venous obstruction is relatively prevalent in patients with chronic venous disease. Endovascular treatments and hybrid interventions can be used to relieve venous outflow obstructions. This paper assesses mid-term clinical outcomes and patency rates in a large cohort after percutaneous and hybrid interventions. METHODS: This was a prospectively analysed cohort study. Patients with symptomatic deep venous obstruction who presented at a tertiary referral hospital were divided into three groups: patients who underwent percutaneous stenting for non-thrombotic iliac vein compression syndrome (IVCS group); patients with post-thrombotic syndrome (PTS) treated by percutaneous stent placement (P-PTS group); and PTS patients with obstruction involving the veins below the saphenofemoral junction in which a hybrid procedure was performed, combining stenting with open surgical disobliteration (H-PTS group). Patency rates, complications, and clinical outcomes were analysed. RESULTS: A total of 425 lower extremities in 369 patients were treated. At 60 months, primary patency, assisted primary patency, and secondary patency rates were 90%, 100%, and 100% for IVCS, and 64%, 81%, and 89% for the P-PTS group, respectively. The H-PTS group, showed patency rates of 37%, 62%, and 72%, respectively, at 36 months. Venous claudication subsided in 90%, 82%, and 83%, respectively. At the 24 month follow-up, mean Venous Clinical Severity Score decreased for all patients and improvement in Villalta score was seen in post-thrombotic patients. The number of complications was related to the extent of deep venous obstruction in which patients in the H-PTS group showed the highest complication rates (81%) and re-interventions (59%). CONCLUSION: Percutaneous stent placement to treat non-thrombotic iliac vein lesions, and post-thrombotic ilio-femoral obstructions are safe, effective, and showed patency rates comparable with previous research. Patients with advanced disease needing a hybrid procedure showed a lower patency rate and more complications. However, when successful, the clinical outcome was favourable at mid-term follow-up and the procedure may be offered to selected patients.


Asunto(s)
Angioplastia/métodos , Vena Femoral/cirugía , Síndrome de May-Thurner/cirugía , Síndrome Postrombótico/cirugía , Adolescente , Adulto , Anciano , Estudios de Cohortes , Femenino , Humanos , Masculino , Síndrome de May-Thurner/diagnóstico por imagen , Persona de Mediana Edad , Síndrome Postrombótico/diagnóstico por imagen , Stents , Resultado del Tratamiento , Grado de Desobstrucción Vascular , Adulto Joven
11.
Eur Arch Otorhinolaryngol ; 274(10): 3605-3612, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28799140

RESUMEN

The objective of the study was to evaluate postoperative hearing and disease control after cholesteatoma surgery for labyrinthine fistulas. In a retrospective cohort study, we evaluated a consecutive cohort comprising 44 patients (45 ears) with labyrinthine fistulas associated with chronic otitis media with cholesteatoma who underwent surgery between 2002 and 2015. We looked at patient characteristics, pre- and postoperative bone conduction thresholds (BCT), operative approach and findings, extent of disease and the occurrence of residual disease. All deaf ears (24%) presented preoperatively with a large fistula. Opening the membranous labyrinth resulted in significantly worse postoperative BCT (p = 0.01). Neither the present study nor a literature search revealed a significant positive effect of corticosteroids on postoperative hearing preservation. Large fistulas were correlated with poorer preoperative BCTs, but not with poorer postoperative BCTs. Opening the membranous labyrinth during surgery is correlated with poorer postoperative BCTs and can be seen as a predictive parameter. The use of corticosteroids in the perioperative management of labyrinthine fistula was not found to result in any improvement in postoperative BCTs.


Asunto(s)
Colesteatoma del Oído Medio/complicaciones , Fístula , Pérdida Auditiva , Enfermedades del Laberinto , Otitis Media/complicaciones , Complicaciones Posoperatorias , Conducción Ósea , Oído Interno/patología , Oído Interno/fisiopatología , Oído Interno/cirugía , Femenino , Fístula/etiología , Fístula/cirugía , Glucocorticoides/uso terapéutico , Audición , Pérdida Auditiva/diagnóstico , Pérdida Auditiva/etiología , Pérdida Auditiva/prevención & control , Pruebas Auditivas/métodos , Humanos , Enfermedades del Laberinto/etiología , Enfermedades del Laberinto/cirugía , Masculino , Persona de Mediana Edad , Evaluación de Resultado en la Atención de Salud , Complicaciones Posoperatorias/diagnóstico , Complicaciones Posoperatorias/fisiopatología , Complicaciones Posoperatorias/terapia , Estudios Retrospectivos
12.
Acta Anaesthesiol Scand ; 61(6): 580-589, 2017 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-28436022

RESUMEN

BACKGROUND: A small tube may facilitate tracheal intubation and improve surgical access. We describe our initial experience with the Tritube® that is a novel cuffed endotracheal tube with a 2.4 mm internal diameter. METHODS: The Tritube® was used in seven adult Ear-Nose-and Throat surgical patients with airway narrowing or whose surgical access was facilitated by this small-bore endotracheal tube. Ventilation through Tritube® is performed with the manually operated Ventrain® -ventilator that allows active suctioning during expiration, therefore facilitating normoventilation through small diameter airways. RESULTS: The small diameter of Tritube® seemed to improve glottis visualisation during intubations and gave excellent working conditions for surgery. Two patients were intubated awake with a flexible scope and a guide wire or with an angulated video laryngoscope. One patient had almost complete glottic occlusion that just allowed for passage of the Tritube® . Adequate ventilation was achieved in all patients and intratracheal pressure was kept between 5 and 20 cm H2 O. The tube was well tolerated after emergence from anaesthesia and kept intratracheally in five awake patients in the post-operative recovery unit, in one case for more than 1 h. Ventilating with Ventrain® through Tritube® demands meticulous breath by breath measurement and adjustment of the intratracheal pressure. CONCLUSION: The 2.4 mm internal diameter Tritube® seems to facilitate tracheal intubation and to provide unprecedented view of the intubated airway during oral, pharyngeal, laryngeal or tracheal procedures in adults. This technique has the potential to replace temporary tracheostomy, jet-ventilation or extra-corporal membrane oxygenation in selected patients.


Asunto(s)
Manejo de la Vía Aérea/instrumentación , Respiración Artificial/instrumentación , Anciano , Presión del Aire , Manejo de la Vía Aérea/métodos , Resistencia de las Vías Respiratorias , Anestesia , Periodo de Recuperación de la Anestesia , Femenino , Glotis/anatomía & histología , Humanos , Intubación Intratraqueal , Laringoscopía , Masculino , Persona de Mediana Edad , Procedimientos Quirúrgicos Otorrinolaringológicos , Respiración Artificial/métodos , Succión
14.
Br J Surg ; 104(6): 718-725, 2017 May.
Artículo en Inglés | MEDLINE | ID: mdl-28221670

RESUMEN

BACKGROUND: Good results have been reported for angioplasty and stenting of post-thrombotic lesions of the iliac and proximal femoral veins. If lesions at the origin of the superficial femoral and profunda veins are stented, the intraluminal synechiae can be pushed against the orifices of inflow vessels, potentially decreasing stent inflow. Surgical disobliteration of the common femoral vein (endophlebectomy) has been suggested to mitigate this problem. Because of a temporary increase in thrombogenicity, this procedure may be accompanied by arteriovenous fistula creation. METHODS: Data on consecutive patients treated by hybrid venous reconstruction, between December 2010 and May 2015, were analysed. Standard recording consisted of clinical scoring systems (including Villalta scale) and imaging. Patency was assessed with duplex ultrasonography. RESULTS: Seventy-six legs (70 patients) were included. Median follow-up was 379 (range 73-1508) days. Primary, assisted primary and secondary patency rates at 12 months were 51, 70 and 83 per cent respectively. Sixty per cent of loss of primary patency (24 of 40 legs) was related to common femoral vein stenosis, and the rest to rethrombosis. Other complications included wound infection (29 per cent) and lymphatic leak (39 per cent). The Villalta score had decreased by a median of 7 points at 1-year follow-up. CONCLUSION: The combination of venous stenting, endophlebectomy and arteriovenous fistula creation for patients with extensive post-thrombotic vein damage and severe post-thrombotic syndrome is feasible.


Asunto(s)
Derivación Arteriovenosa Quirúrgica/métodos , Vena Femoral/cirugía , Flebotomía/métodos , Síndrome Postrombótico/cirugía , Adolescente , Adulto , Cuidados Posteriores , Anciano , Derivación Arteriovenosa Quirúrgica/efectos adversos , Estudios de Factibilidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Flebotomía/efectos adversos , Complicaciones Posoperatorias/etiología , Estudios Prospectivos , Recurrencia , Reoperación , Factores de Riesgo , Stents , Resultado del Tratamiento , Grado de Desobstrucción Vascular/fisiología , Adulto Joven
15.
J Laryngol Otol ; 131(2): 138-143, 2017 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-28069077

RESUMEN

OBJECTIVE: This study aimed to evaluate the results of revision radical cavity surgery with mastoid obliteration using a standardised grading scheme. METHODS: A retrospective study was performed of 121 patients (122 ears) with chronically draining ears who underwent revision radical cavity surgery with mastoid obliteration between 2007 and 2013. Surgical indications, patient characteristics, pre- and post-operative Merchant grade, and surgical outcomes were recorded. The main outcome measures were presence of a dry ear, time for complete re-epithelialisation, presence of residual or recurrent disease, and need for revision surgery. RESULTS: In the 5-year follow-up group (n = 31), dry ears were found in 97 per cent after 6 minor revisions and cholesteatoma-free ears were found in 97 per cent. In the total cohort, dry ears were found in 93 per cent after nine revisions and cholesteatoma-free ears were found in 98 per cent. The median time for complete re-epithelialisation was eight weeks. There were no major complications. CONCLUSION: In terms of the dry ear rate, residual cholesteatoma and time to complete epithelialisation, revision radical cavity surgery with mastoid obliteration produces very good results in concordance with published results, despite most patients suffering from very troublesome cavities prior to surgery.


Asunto(s)
Colesteatoma del Oído Medio/cirugía , Conducto Auditivo Externo/cirugía , Apófisis Mastoides/cirugía , Timpanoplastia/métodos , Adolescente , Adulto , Anciano , Niño , Enfermedad Crónica , Enfermedades del Oído/cirugía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Procedimientos Quirúrgicos Otológicos/métodos , Reoperación , Estudios Retrospectivos , Adulto Joven
17.
Gefasschirurgie ; 21(Suppl 2): 37-44, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27546987

RESUMEN

BACKGROUND: Postthrombotic syndrome (PTS) is the development of symptoms and signs of chronic venous insufficiency following deep vein thrombosis (DVT) and has a significant negative effect on the quality of life. The current understanding is that the clinical manifestation of PTS is related more to venous obstruction than it is to venous reflux. The use of interventional techniques for the treatment of venous obstruction and/or venous occlusion has rapidly increased in recent years. OBJECTIVE: This article summarizes the current concept of endovenous and hybrid interventions and presents the optimized treatment of choice in patients with chronic symptomatic venous obstruction. METHODS: We performed a systematic literature search in the Medline database to identify relevant studies on the treatment of patients with PTS. RESULTS: A meta-analysis of the relevant studies showed that this minimally invasive procedure is an effective treatment option with low morbidity and no mortality. Use of the newly developed dedicated venous stents showed promising results with good mid-term patency rates and a significant decrease in related symptoms. CONCLUSION: Interventional therapy for the treatment of symptomatic chronic venous obstruction has become the method of choice in recent years. More studies are needed to evaluate the long-term success rate of dedicated venous stents.

18.
J Thromb Haemost ; 14(6): 1163-70, 2016 06.
Artículo en Inglés | MEDLINE | ID: mdl-27061685

RESUMEN

UNLABELLED: Essentials Little is known about the hemodynamic consequences of deep venous obstructive disease. We investigated pressure changes in 22 patients with unilateral postthrombotic obstruction. Common femoral vein pressure significantly increased after walking, compared to control limbs. Common femoral vein hypertension could explain the debilitating effect of venous claudication. Click to hear Dr Ten Cate's perspective on postthrombotic syndrome SUMMARY: Background Little is known about the hemodynamic consequences of deep venous obstructive disease. Objectives The aim of this study was to investigate the hemodynamic effect of postthrombotic obstruction of the iliofemoral veins and to determine what pressure parameters differentiate best between limbs with post-thrombotic obstructive disease of the iliofemoral veins and those without obstruction. Methods Twenty-two participants with unilateral obstruction of the iliac and common femoral veins underwent a standardized treadmill test with simultaneous bilateral invasive pressure measurements in the common femoral vein and dorsal foot vein. Results Mean age was 42.8 ± 11.9 years and 86.4% of participants were female. Postthrombotic limbs showed a mean common femoral vein (CFV) pressure increase of 28.1 ± 21.0 mmHg after walking, compared with 2.1 ± 6.2 mmHg in control limbs (26.0 mmHg difference; 95% confidence interval [CI], 17.1-34.9). Less difference was observed in the dorsal foot vein (net drop of 36.8 ± 22.7 mmHg in affected limbs vs. 48.7 ± 23.1 mmHg in non-affected limbs, 11.9 mmHg difference; 95% CI, -1.3 to 25.0). Change in CFV pressure after walking yielded the best discrimination between affected and non-affected limbs (area under the receiver operated characteristic curve of 0.94 [95% CI, 0.85-1.00], compared with 0.57 [95% CI, 0.37-0.76] in the dorsal foot vein, P < 0.001). Conclusions Common femoral vein pressure significantly increases during ambulation in patients with iliofemoral postthrombotic obstruction, which could explain the debilitating effects of venous claudication. This is an indication that patients with an iliofemoral obstruction may benefit from further treatment that resolves the deep vein obstruction. CLINICAL TRIAL REGISTRATION: https://clinicaltrials.gov/show/NCT01846780.


Asunto(s)
Presión Sanguínea , Prueba de Esfuerzo , Vena Femoral/patología , Síndrome Postrombótico/fisiopatología , Adulto , Estudios de Casos y Controles , Femenino , Vena Femoral/fisiopatología , Hemodinámica , Humanos , Vena Ilíaca/fisiopatología , Masculino , Persona de Mediana Edad , Flebografía , Proyectos Piloto , Curva ROC , Stents , Enfermedades Vasculares , Insuficiencia Venosa
19.
Eur J Vasc Endovasc Surg ; 50(4): 518-26, 2015 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-26187656

RESUMEN

OBJECTIVE: Deep venous stenting has become the primary treatment option for chronic venous obstructive disease, both for iliac vein compression and post-thrombotic venous lesions. Until recently, only stents aimed at arterial pathology were used, because no dedicated venous stents were available. However, three such stents have now become available. These venous stents are characterized by increased length, diameter, flexibility, and radial force. This study reports an early experience with one of these devices; the sinus Venous stent (OptiMed GmbH, Ettlingen, Germany). METHODS: Between March 2012 and July 2014, 75 patients were treated with the sinus Venous stent: 35 cases of iliac vein compression syndrome and 40 cases of unilateral chronic obstruction in post-thrombotic syndrome (PTS). Diagnosis of relevant obstruction was made using clinical evaluation, duplex ultrasound, and magnetic resonance venography. Patency during follow up was assessed with duplex ultrasound. Clinical improvement was assessed by VCSS, Villalta score, rate of ulcer healing, and improvement of venous claudication. RESULTS: The cumulative patency rates at 3, 6, and 12 months were 99%, 96%, and 92%, respectively. The cumulative assisted primary patency rates were 99% at 3, 6, and 12 months. The cumulative secondary patency rate at 12 months was 100%. Differences exist in patency rate between the subgroups of non-thrombotic and post-thrombotic, with the first showing no re-occlusions. All re-thromboses in the PTS group were treated by ancillary treatment modalities. VCSS and Villalta score decreased significantly after stenting, as did venous claudication. Morbidity was low without clinically relevant pulmonary embolism, and mortality was nil. Although two out of seven ulcers healed temporarily, no ulcer remained healed at 12 months follow up. CONCLUSION: Short-term clinical results using the sinus Venous stent are excellent, with significant symptom reduction, low morbidity rates, and no mortality. Loss of stent patency is seen less often compared with arterial stents described in the literature.


Asunto(s)
Aleaciones , Angioplastia de Balón/instrumentación , Vena Ilíaca , Síndrome de May-Thurner/terapia , Síndrome Postrombótico/terapia , Stents , Adolescente , Adulto , Anciano , Angioplastia de Balón/efectos adversos , Enfermedad Crónica , Femenino , Humanos , Vena Ilíaca/diagnóstico por imagen , Vena Ilíaca/fisiopatología , Claudicación Intermitente/terapia , Estimación de Kaplan-Meier , Úlcera de la Pierna/terapia , Angiografía por Resonancia Magnética , Masculino , Síndrome de May-Thurner/diagnóstico , Síndrome de May-Thurner/fisiopatología , Persona de Mediana Edad , Países Bajos , Flebografía/métodos , Síndrome Postrombótico/diagnóstico , Síndrome Postrombótico/fisiopatología , Diseño de Prótesis , Recurrencia , Centros de Atención Terciaria , Factores de Tiempo , Resultado del Tratamiento , Ultrasonografía Doppler Dúplex , Grado de Desobstrucción Vascular , Cicatrización de Heridas , Adulto Joven
20.
Tijdschr Psychiatr ; 57(5): 361-6, 2015.
Artículo en Holandés | MEDLINE | ID: mdl-26028017

RESUMEN

Takotsubo cardiomyopathy is an acute, stress-induced, reversible cardiac syndrome and can occur as a rare complication in electroconvulsive therapy. We give further details of this complication by referring to the case of a 67-year-old female patient. In addition, we give a brief description of the background of the syndrome. If this syndrome is suspected, the patient should immediately be referred for cardiac diagnostic tests to rule out myocardial infarction. There is no absolute contra-indication to ECT for a patient who has experienced Takotsubo cardiomyopathy. However, to start ECT treatment again it is recommended that this should be performed in a general hospital and in combination with beta-blockers.


Asunto(s)
Terapia Electroconvulsiva/efectos adversos , Cardiomiopatía de Takotsubo/etiología , Anciano , Femenino , Humanos , Aturdimiento Miocárdico/etiología
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