RESUMEN
AIMS: The aim of the present study was to investigate the presence of immunoglobulins (Ig) in whole saliva from patients affected by autoimmune hepatitis (AIH). DESIGN: Twelve individuals with AIH and 12 healthy individuals without (CON) autoimmune hepatitis, aged 8-18 years, participated in this study. Non-stimulated whole saliva was collected and centrifuged. Supernatants were separated and lyophilized. Salivary pH was measured and immunoglobulins were analyzed through ELISA technique. RESULTS: Salivary pH (CON, 7.17⯱â¯0.45; AIH, 6.92⯱â¯0.43) did not differ between groups (pâ¯=â¯0.183). Measurable levels of IgG, IgA, IgM and IgE were detected on all patients. IgG levels were higher in AIH individuals (CON, 1.058⯱â¯0.386; AIH, 1.635⯱â¯0.373; pâ¯=â¯0.001), whereas IgA (CON, 0.915⯱â¯0.187; AIH, 0.995⯱â¯0.235; pâ¯=â¯0.362), IgM (CON, 0.683⯱â¯0.147, AIH, 0.646⯱â¯0.161; pâ¯=â¯0.561) and IgE levels (CON, 1.241⯱â¯0.378; AIH, 1.312⯱â¯0.412; pâ¯=â¯0.664) did not present differences between groups. CONCLUSIONS: The results of the present study suggest differences in salivary IgG levels between individuals with and without AIH. Thus, saliva has the potential of becoming an important diagnostic tool for the assessment of AIH.
Asunto(s)
Hepatitis Autoinmune/inmunología , Hipergammaglobulinemia/inmunología , Inmunoglobulinas/análisis , Inmunoglobulinas/inmunología , Saliva/química , Adolescente , Niño , Ensayo de Inmunoadsorción Enzimática , Femenino , Humanos , Concentración de Iones de Hidrógeno , Inmunoglobulina G/análisis , Inmunoglobulina G/inmunología , MasculinoRESUMEN
This is a descriptive study developed in the outpatient unit of a university maternity hospital in the city of Natal/RN. It aimed at identifying the knowledge about and alterations found during breast self-examination as well as at describing how women examine themselves. The population was formed by patients sent by other health services and the sample consisted of 109 women with age varying from 15 to 83 years. In order to collect data, the authors used a form containing identification information as well as about breast self-examination. Based on the collected data, they identified that among the 109 participants, the age of 36 (33%) of them varied from 15 to 39 years; of 58 (53%) of them from 40 to 58 years and of 15 (14%) of them from 60 to 83 years. 75% reported that they examined themselves and that they attended a health care service for correct treatment in case any alterations were detected during self-examination.