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1.
Lett Appl Microbiol ; 54(6): 564-7, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-22414147

RESUMEN

AIMS: The objective of this study was to assess the antimicrobial efficacy of alcohol-based hand gels according to European Norm 1500 (EN 1500). METHODS AND RESULTS: We assessed the antimicrobial efficacy of 12 alcohol-based hand gels produced in Brazil, containing 70% w/w or v/v ethyl alcohol as the active ingredient, according to EN 1500, with a 30-s application. In addition, 70% w/w ethyl alcohol and three alcohol-based hand rubs commonly used in Europe and effective according to EN 1500 were also tested. Eight of 12 (67%) alcohol-based hand gels produced in Brazil failed by EN 1500. In contrast, 70% w/w ethyl alcohol and European alcohol-based hand rubs were approved by EN 1500. CONCLUSIONS: In this study, the majority of Brazilian alcohol-based hand gels showed limited efficacy on hand hygiene within 30 s. SIGNIFICANCE AND IMPACT OF THE STUDY: The findings of this study may be used as an important argument to motivate Brazilian manufacturers to improve the antimicrobial efficacy of alcohol-based hand gels, because it is prudent to suppose that alcohol-based hand gels can be recommended for use in healthcare settings only if they show antimicrobial activity at least similar to that of alcohol-based liquid preparations, including the traditional 70% w/w ethyl alcohol.


Asunto(s)
Alcoholes/farmacología , Antiinfecciosos Locales/farmacología , Desinfección de las Manos/métodos , Antiinfecciosos Locales/normas , Brasil , Enterococcus faecalis/efectos de los fármacos , Etanol/farmacología , Europa (Continente) , Geles , Mano/microbiología , Humanos , Pseudomonas aeruginosa/efectos de los fármacos , Staphylococcus aureus/efectos de los fármacos , Factores de Tiempo
2.
Acta Biomater ; 6(3): 1069-78, 2010 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-19788943

RESUMEN

This study reports on the performance of electrospun hyperbranched polyglycerol nanofibers capable of providing an active agent delivery for wound dressing applications. The aim of this work was to prepare electrospun HPGL nanofibers containing Calendula officinalis as a wound-healing and anti-inflammatory agent. The morphology of the electrospun HPGL-C. officinalis nanofibers was analyzed using a scanning electron microscope. The results showed that the diameters of the fibers were in nanoscales. The release of C. officinalis from the electrospun HPGL fibers was determined by HPLC at a physiological temperature (37 degrees C). Rapid release of the C. officinalis from the electrospun HPGL-C. officinalis nanofibers was exhibited as result of the high swelling ability as well as the high porosity of the electrospun HPGL-C. officinalis membranes. The degree of swelling, and the mechanical and biocompatible properties of the electrospun HPGL fibers were determined. The results showed that, in physiological conditions, the water absorption into the HPGL electrospun fibers slowed down, governed by the rate at which the electrospun HPGL-C. officinalis membranes interacted with the physiological fluid. The rate of release of C. officinalis seemed to depend on the C. officinalis content in the HPGL nanofibers. From the elastic modulus, it could be seen that elastic electrospun HPGL fibers were obtained with increments of C. officinalis content in the HPGL-C. officinalis membranes. The results of in vivo experiments in rats suggested that HPGL-C. officinalis might be an interesting bioactive wound dressing material for clinical applications.


Asunto(s)
Vendajes , Electroquímica/métodos , Glicerol/química , Nanoestructuras/química , Nanoestructuras/uso terapéutico , Polímeros/química , Piel/citología , Piel/efectos de los fármacos , Absorción , Animales , Cristalización/métodos , Diseño de Equipo , Análisis de Falla de Equipo , Glicerol/efectos adversos , Ensayo de Materiales , Nanoestructuras/efectos adversos , Polímeros/efectos adversos , Porosidad , Conejos , Rotación
3.
Cad Saude Publica ; 16(1): 195-204, 2000.
Artículo en Portugués | MEDLINE | ID: mdl-10738164

RESUMEN

This article analyzes the issue of workers' health in the context of productive reorganization, based on the sexual division of labor and gender relations. The author begins with a discussion of cross-cutting issues and moves on to analyze current trends: the increase in female labor, its incorporation by multinational companies in the so-called Third World countries, an increase in differences and greater vulnerability vis-à-vis the process involving underemployment and suspension of social labor clauses. Finally, two examples of female labor (in industry and the school system) foster reflection on the effect of productive reorganization on working women's health, highlighting the issue of excessive workloads for women.


Asunto(s)
Empleo/tendencias , Salud Laboral , Salud de la Mujer , Mujeres Trabajadoras , Países en Desarrollo , Femenino , Humanos , Masculino , Factores Sexuales
4.
Cad Saude Publica ; 11(4): 543-51, 1995.
Artículo en Portugués | MEDLINE | ID: mdl-12973589

RESUMEN

This article presents a case study on working and health conditions of female workers and former workers in the laundry at a sodium chlorate plant. The women's main function was to wash uniforms of workmen who handled metallic mercury during production and maintenance. The aim of this study is to show the health effects of this work process by analyzing workplace conditions, evaluating clinical aspects in the women, and performing individual interviews in order to obtain more precise information based on their personal experience. The authors demonstrate how harmful this type of work is to the women workers' health, posing a serious risk for them in particular and workers' conditions in general in the factory. They also point out that most of what is known about women's occupational activity (in terms of its contents and risks), in addition to their specific problems and different diseases, may be disguised by gender relationships.

5.
Cad Saude Publica ; 7(2): 201-14, 1991.
Artículo en Portugués | MEDLINE | ID: mdl-15830042

RESUMEN

The present paper aims at showing the importance of the gender approach in the theoretical construction of the field of worker's health since men and women are exposed to different work conditions within the productive process. In the case of female workers, we point to the liaison of capitalism and patriarchy as determinants of women's oppression in the hierarchical relationships of labor as well as to the hidden social responsibility of the housework, which is carried out in the private sphere thus keeping women distant from the social and political world and generating strong impacts on their health. According to the sexual division of labor, female work in industry is restricted to rather repetitive tasks that require a great nervous resistance - not especially healthy conditions that lead to a specific consuming pattern. We concluded that changes should occur in the social life schemes, besides breaking with the myths that support the sexual division of labor, so that the aggressive conditions imposed on men and women's health in the work process can be altered.

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